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Matrix Metalloproteinase 9 (Gelatinase B or 92 kDa Type IV Collagenase or 92 kDa Gelatinase or MMP9 or EC 3.4.24.35) Drugs in Development by Therapy Areas and Indications, Stages, MoA, RoA, Molecule Type and Key Players, 2022 Update

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    Report

  • 56 Pages
  • August 2022
  • Region: Global
  • Global Markets Direct
  • ID: 5654070
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Matrix Metalloproteinase 9 (Gelatinase B or 92 kDa Type IV Collagenase or 92 kDa Gelatinase or MMP9 or EC 3.4.24.35) pipeline Target constitutes close to 19 molecules. Out of which approximately 14 molecules are developed by companies and remaining by the universities/institutes. The latest report Matrix Metalloproteinase 9 - Drugs In Development, 2022, outlays comprehensive information on the Matrix Metalloproteinase 9 (Gelatinase B or 92 kDa Type IV Collagenase or 92 kDa Gelatinase or MMP9 or EC 3.4.24.35) targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type.

Matrix Metalloproteinase 9 (Gelatinase B or 92 kDa Type IV Collagenase or 92 kDa Gelatinase or MMP9 or EC 3.4.24.35) - Matrix metallopeptidase 9 (MMP-9) is a matrixin that belong to the zinc-metalloproteinases family. It plays an essential role in local proteolysis of the extracellular matrix and in leukocyte migration and bone osteoclastic resorption. MMP9 along with elastase, appears to be a regulatory factor in neutrophil migration across the basement membrane. MMP9 may play an important role in wound repair, angiogenesis and neovascularization. The molecules developed by companies in Phase II, Phase I, Preclinical and Discovery stages are 1, 1, 11 and 1 respectively. Similarly, the universities portfolio in Preclinical stages comprises 5 molecules, respectively.

Report covers products from therapy areas Central Nervous System, Oncology, Dermatology, Gastrointestinal, Cardiovascular, Immunology, Musculoskeletal Disorders, Ophthalmology, Respiratory, Infectious Disease, Metabolic Disorders and Undisclosed which include indications Epilepsy, Neuropathic Pain (Neuralgia), Osteoarthritis Pain, Wounds, Acute Ischemic Stroke, Amyotrophic Lateral Sclerosis, Atopic Dermatitis (Atopic Eczema), Burns, Cancer Pain, Chemotherapy Induced Pain, Crohn's Disease (Regional Enteritis), Diabetic Neuropathy, Dupuytren Contracture, Fibrosis, Genital Herpes, Herpes Labialis (Oral Herpes), Herpes Zoster (Shingles), Herpetic Keratitis, Inflammation, Inflammatory Bowel Disease, Keratoconjunctivitis Sicca (Dry Eye), Liver Fibrosis, Melanoma, Metastatic Cancer, Metastatic Melanoma, Myocardial Infarction, Ocular Pain (Eye Pain), Opium (Opioid) Addiction, Pancreatic Islet Transplant Rejection, Pulmonary Fibrosis, Pulmonary Inflammation, Simplexvirus (HSV) Infections, Spinal Cord Injury and Unspecified.

Furthermore, this report also reviews key players involved in Matrix Metalloproteinase 9 (Gelatinase B or 92 kDa Type IV Collagenase or 92 kDa Gelatinase or MMP9 or EC 3.4.24.35) targeted therapeutics development with respective active and dormant or discontinued projects. Driven by data and information sourced from proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources.

Note: Certain content/sections in the pipeline guide may be removed or altered based on the availability and relevance of data.

Scope

  • The report provides a snapshot of the global therapeutic landscape for Matrix Metalloproteinase 9 (Gelatinase B or 92 kDa Type IV Collagenase or 92 kDa Gelatinase or MMP9 or EC 3.4.24.35)
  • The report reviews Matrix Metalloproteinase 9 (Gelatinase B or 92 kDa Type IV Collagenase or 92 kDa Gelatinase or MMP9 or EC 3.4.24.35) targeted therapeutics under development by companies and universities/research institutes based on information derived from company and industry-specific sources
  • The report covers pipeline products based on various stages of development ranging from pre-registration till discovery and undisclosed stages
  • The report features descriptive drug profiles for the pipeline products which includes, product description, descriptive MoA, R&D brief, licensing and collaboration details & other developmental activities
  • The report reviews key players involved in Matrix Metalloproteinase 9 (Gelatinase B or 92 kDa Type IV Collagenase or 92 kDa Gelatinase or MMP9 or EC 3.4.24.35) targeted therapeutics and enlists all their major and minor projects
  • The report assesses Matrix Metalloproteinase 9 (Gelatinase B or 92 kDa Type IV Collagenase or 92 kDa Gelatinase or MMP9 or EC 3.4.24.35) targeted therapeutics based on mechanism of action (MoA), route of administration (RoA) and molecule type
  • The report summarizes all the dormant and discontinued pipeline projects
  • The report reviews latest news and deals related to Matrix Metalloproteinase 9 (Gelatinase B or 92 kDa Type IV Collagenase or 92 kDa Gelatinase or MMP9 or EC 3.4.24.35) targeted therapeutics

Reasons to Buy

  • Gain strategically significant competitor information, analysis, and insights to formulate effective R&D strategies
  • Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
  • Identify and understand the targeted therapy areas and indications for Matrix Metalloproteinase 9 (Gelatinase B or 92 kDa Type IV Collagenase or 92 kDa Gelatinase or MMP9 or EC 3.4.24.35)
  • Identify the use of drugs for target identification and drug repurposing
  • Identify potential new clients or partners in the target demographic
  • Develop strategic initiatives by understanding the focus areas of leading companies
  • Plan mergers and acquisitions effectively by identifying key players and it’s most promising pipeline therapeutics
  • Devise corrective measures for pipeline projects by understanding Matrix Metalloproteinase 9 (Gelatinase B or 92 kDa Type IV Collagenase or 92 kDa Gelatinase or MMP9 or EC 3.4.24.35) development landscape
  • Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope

Table of Contents

  • Introduction
  • Report Coverage
  • Matrix Metalloproteinase 9 (Gelatinase B or 92 kDa Type IV Collagenase or 92 kDa Gelatinase or MMP9 or EC 3.4.24.35) - Overview
  • Matrix Metalloproteinase 9 (Gelatinase B or 92 kDa Type IV Collagenase or 92 kDa Gelatinase or MMP9 or EC 3.4.24.35) - Therapeutics Development
  • Products under Development by Stage of Development
  • Products under Development by Therapy Area
  • Products under Development by Indication
  • Products under Development by Companies
  • Products under Development by Universities/Institutes
  • Matrix Metalloproteinase 9 (Gelatinase B or 92 kDa Type IV Collagenase or 92 kDa Gelatinase or MMP9 or EC 3.4.24.35) - Therapeutics Assessment
  • Assessment by Mechanism of Action
  • Assessment by Route of Administration
  • Assessment by Molecule Type
  • Matrix Metalloproteinase 9 (Gelatinase B or 92 kDa Type IV Collagenase or 92 kDa Gelatinase or MMP9 or EC 3.4.24.35) - Companies Involved in Therapeutics Development
  • Accure Therapeutics SL
  • Aquilus Pharmaceuticals Inc
  • AstraZeneca Plc
  • EA Pharma Co Ltd
  • Elastomics AB
  • Iproteos SL
  • MabTrix Ltd
  • Pharmahungary Group
  • Pikralida Sp zoo
  • Proteris Biotech Inc
  • Releviate Therapeutics
  • Shulov Innovative Science Ltd
  • Translational Sciences Inc
  • Matrix Metalloproteinase 9 (Gelatinase B or 92 kDa Type IV Collagenase or 92 kDa Gelatinase or MMP9 or EC 3.4.24.35) - Drug Profiles
  • ACT-03 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • History of Events
  • AQU-010 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • History of Events
  • AQU-118 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • History of Events
  • AZD-1236 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • History of Events
  • CALY-001 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • History of Events
  • IPRO-003 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • History of Events
  • M-9i - Drug Profile
  • Product Description
  • Mechanism Of Action
  • History of Events
  • Monoclonal Antibody to Inhibit MMP9 for Inflammatory Bowel Disease - Drug Profile
  • Product Description
  • Mechanism Of Action
  • ND-336 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • PKL-021 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • Protearin - Drug Profile
  • Product Description
  • Mechanism Of Action
  • History of Events
  • Recombinant MMP-9 Replacement for Liver Fibrosis, Pulmonary Fibrosis, Peyronies Disease, Dupuytren Contracture and Pancreatic Islet Transplant Rejection - Drug Profile
  • Product Description
  • Mechanism Of Action
  • Recombinant Protein to Target MMP-9 for Wounds - Drug Profile
  • Product Description
  • Mechanism Of Action
  • RLVT-903 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • History of Events
  • Small Molecule to Inhibit Matrix Metalloproteinase 9 for Oncology - Drug Profile
  • Product Description
  • Mechanism Of Action
  • Small Molecules to Inhibit Carbonic Anhydrases and MMPs for Metastatic Melanoma - Drug Profile
  • Product Description
  • Mechanism Of Action
  • Small Molecules to Inhibit MMP 2,9 and 13 for Myocardial Infarction - Drug Profile
  • Product Description
  • Mechanism Of Action
  • Vaccine to Target MMP2 and MMP9 for Melanoma - Drug Profile
  • Product Description
  • Mechanism Of Action
  • History of Events
  • ZEP-3 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • History of Events
  • Matrix Metalloproteinase 9 (Gelatinase B or 92 kDa Type IV Collagenase or 92 kDa Gelatinase or MMP9 or EC 3.4.24.35) - Dormant Products
  • Matrix Metalloproteinase 9 (Gelatinase B or 92 kDa Type IV Collagenase or 92 kDa Gelatinase or MMP9 or EC 3.4.24.35) - Discontinued Products
  • Matrix Metalloproteinase 9 (Gelatinase B or 92 kDa Type IV Collagenase or 92 kDa Gelatinase or MMP9 or EC 3.4.24.35) - Product Development Milestones
  • Featured News & Press Releases
  • May 20, 2022: Birmingham research brings hope for spinal cord injury treatment
  • Jul 12, 2021: Co-financing from 3/1.1.1/2020 fast track for Mazovia competition
  • Nov 07, 2018: California research team publishes promising results from peptide based universal cancer vaccine
  • Appendix
  • Methodology
  • Coverage
  • Secondary Research
  • Primary Research
  • Expert Panel Validation
  • Contact the Publisher
  • Disclaimer
List of Tables
  • Number of Products under Development by Stage of Development, 2022
  • Number of Products under Development by Therapy Areas, 2022
  • Number of Products under Development by Indications, 2022
  • Number of Products under Development by Companies, 2022
  • Products under Development by Companies, 2022
  • Products under Development by Companies, 2022 (Contd..1)
  • Number of Products under Investigation by Universities/Institutes, 2022
  • Products under Investigation by Universities/Institutes, 2022
  • Number of Products by Stage and Mechanism of Actions, 2022
  • Number of Products by Stage and Route of Administration, 2022
  • Number of Products by Stage and Molecule Type, 2022
  • Pipeline by Accure Therapeutics SL, 2022
  • Pipeline by Aquilus Pharmaceuticals Inc, 2022
  • Pipeline by AstraZeneca Plc, 2022
  • Pipeline by EA Pharma Co Ltd, 2022
  • Pipeline by Elastomics AB, 2022
  • Pipeline by Iproteos SL, 2022
  • Pipeline by MabTrix Ltd, 2022
  • Pipeline by Pharmahungary Group, 2022
  • Pipeline by Pikralida Sp zoo, 2022
  • Pipeline by Proteris Biotech Inc, 2022
  • Pipeline by Releviate Therapeutics, 2022
  • Pipeline by Shulov Innovative Science Ltd, 2022
  • Pipeline by Translational Sciences Inc, 2022
  • Dormant Products, 2022
  • Dormant Products, 2022 (Contd..1)
  • Dormant Products, 2022 (Contd..2)
  • Dormant Products, 2022 (Contd..3)
  • Discontinued Products, 2022
List of Figures
  • Number of Products under Development by Stage of Development, 2022
  • Number of Products under Development by Therapy Areas, 2022
  • Number of Products under Development by Top 10 Indications, 2022
  • Number of Products by Stage and Mechanism of Actions, 2022
  • Number of Products by Routes of Administration, 2022
  • Number of Products by Stage and Routes of Administration, 2022
  • Number of Products by Molecule Types, 2022
  • Number of Products by Stage and Molecule Types, 2022

Companies Mentioned (Partial List)

A selection of companies mentioned in this report includes, but is not limited to:

  • Accure Therapeutics SL
  • Aquilus Pharmaceuticals Inc
  • AstraZeneca Plc
  • EA Pharma Co Ltd
  • Elastomics AB
  • Iproteos SL
  • MabTrix Ltd
  • Pharmahungary Group
  • Pikralida Sp zoo
  • Proteris Biotech Inc
  • Releviate Therapeutics
  • Shulov Innovative Science Ltd
  • Translational Sciences Inc