Coronavirus disease 2019 (COVID-19) has affected millions of people across the world. Clinicians and scientists across the globe need all the information of this pandemic on one platform. Today, it is also necessary to find out the association of COVID-19 with various medical comorbidities, and its effect on vulnerable populations that require special medical attention. This information will be helpful for the management of COVID-19.
COVID-19: Effects in Comorbidities and Special Populations is a concise and visual reference for information about this viral disease and its relationship with different medical conditions. The book provides comprehensive knowledge covering COVID-19 comorbidities (for example, CVD, Diabetes, lung diseases, etc.), and the incidence in specific groups (for example, children and the elderly). Chapters outline the features and the management of the disease in specific conditions.
Key Features:
- 12 chapters covering several aspects of COVID-19 management, making this a perfect text book for virologist and medical students
- Focused and structured description of different effects of COVID-19 in specific patient groups
- Multiple tables and figures which summarizes and highlight important points
- Multiple choice questions for learners
- Detailed list of references, abbreviations and symbols
This book is an essential reference for practicing and training virologists, pulmonologists, medical students and scientists working in research labs, pharmaceutical and biotechnology industries in connection with the control of COVID-19 infection.
Table of Contents
- Introduction
- COVID-19: General Characteristics, Susceptibility, and Association with the Immune System
- COVID-19 and Co-Morbidities
- Diabetes Mellitus
- Obesity and Metabolic Syndrome
- Chronic Kidney Disease
- Cardiovascular Diseases
- Cancer
- Sickle Cell
- Chronic Obstructive Pulmonary Disease
- Conclusion
- Multiple Choice Questions
- List of Abbreviations
- Consent for Publication
- Conflict of Interest
- Acknowledgements
- References
- Sanjay Kumar Bhadada and Rimesh Pal Highlights
- Introduction
- Epidemiology
- Pathophysiological Associations Between Diabetes Mellitus and COVID-19
- Advancing Age
- Comorbidities
- Obesity
- Dysregulated Immune System
- Angiotensin-Converting Enzyme 2 (Ace2) and Diabetes Mellitus
- Coagulation
- Two-Way Interactions Between Diabetes Mellitus and COVID-19
- Does Glycemic Control Before, At, and After Admission Predict Outcomes in COVID-19 Patients with Diabetes Mellitus?
- Glycemic Control Before Hospital Admission
- Plasma Glucose at Hospital Admission
- In-Hospital Glycemic Control
- Anti-Diabetic Medications in COVID-19
- Conclusion
- Multiple Choice Questions
- List of Abbreviations
- Consent for Publication
- Conflict of Interest
- Acknowledgements
- References
- Ashu Rastogi Highlights
- Introduction
- Foot Examination and COVID-19
- Foot Inspection
- Neurological Assessment
- Vascular Assessment
- Diabetic Foot Infections and COVID-19 Pandemic
- an Easy Guide to Antibiotic Therapy is as Follows
- Dfi, COVID-19 and Way Forward
- Charcot Foot and COVID-19
- Preventive Foot Care During COVID-19 Pandemic
- Foot Care in Patients with Pre-Existing Wounds During COVID-19 Pandemic
- Dressing of Foot Wound During COVID -19 Pandemic
- Foot Care for Dfi During COVID-19
- Who Should be Hospitalized for Foot Complications?
- Utilization of Tele-Health Services for Diabetic Foot During COVID-19
- Promote Self Care (Foot) During COVID-19
- Precautions for Health Care Providers
- Conclusion
- Multiple Choice Questions
- List of Abbreviations
- Consent for Publication
- Conflict of Interest
- Acknowledgements
- References
- Rohit Mehtani and Sunil Taneja Highlights
- Introduction
- Gi Tropism of Sars-Cov-2
- Gi Symptomatology
- Relation of Gi Symptoms with COVID-19 Severity
- Possibility of Feco-Oral Transmission of COVID 19?
- Gi Histopathology of Patients with COVID-19
- Management of Gi Symptoms in COVID-19
- Liver Injury with COVID-19
- Mechanisms of Liver Injury
- Role of Ace 2 and Serine Protease
- Direct Cytopathic Effects
- Cytokine Storm
- Ischaemic Hepatitis and Drug Toxicity
- Histopathological Findings in the Liver
- COVID-19 in Patients with Chronic Liver Disease
- Liver Failure due to COVID-19
- Liver Transplantation and COVID-19
- Gi Endoscopy Practices During COVID-19 Pandemic
- Conclusion
- Multiple Choice Questions
- List of Abbreviations
- Consent for Publication
- Conflict of Interest
- Acknowledgements
- References
- Ganesh Kasinadhuni, Vineela Chikkam, Parminder Singh and Rajesh Vijayvergiya Highlights
- Introduction
- Biology of Sars-Cov-2
- Pathophysiology of Sars-Cov-2 Related Tissue Injury
- Ace2 -A Link to Cardiovascular (Cv) Injury
- COVID-19 and Cardiovascular Disease (Cvd)
- COVID-19 and Cardiovascular (Cv) Effects
- Acute Cardiovascular (Cv) Manifestations
- Acute Cardiac Injury and Myocarditis
- Management
- Cardiac Arrhythmias
- Management
- Acute Coronary Syndromes (Acs)
- Management
- Venous Thromboembolism (Vte)
- Management
- Renin-Angiotensin-Aldosterone System (Raas) Inhibitors and Cardiovascular Outcomes in COVID-19 Illness
- Antiviral Drugs and Their Cardiovascular Effects
- Hydroxychloroquine (Hcq) and Azithromycin
- Lopinavir-Ritonavir
- Long-Term Cardiovascular Effects - Long COVID
- Conclusion
- Consent for Publication
- Conflict of Interest
- Acknowledgements
- References
- Niranjan Shiwaji Khaire, Nishant Jindal and Pankaj Malhotra Highlights
- Introduction
- COVID-19 and Hematological Manifestations
- Total Leukocyte Count and Differential Count
- A. Lymphopenia
- B. Neutrophilic Leukocytosis
- C. Thrombocytosis and Thrombocytopenia
- D. Composite Variables: Nlr and Plr Ratios
- E. What is the Clinical Utility of Following These Alterations in the Cbc?
- Coagulation System
- COVID-19 Coagulopathy
- Thrombosis and Thromboembolism
- the Large Vessel Thrombosis (Venous Thromboembolism and Pulmonary Thromboembolism)
- Large Vessel Thrombosis (Arterial, Extracorporeal Circuit Thrombosis)
- Microvascular Thrombosis and Autopsy Data on Thrombosis
- Pathophysiology of Vte and Immunothrombosis in COVID-19
- Acute Illness
- Patient-Related
- Sars-Cov2 Related
- COVID-19 Vs. Non-COVID-19 Illness
- Treatment Implications
- Conclusion
- Multiple Choice Questions
- List of Abbreviations
- Consent for Publication
- Conflict of Interest
- Acknowledgements
- References
- Vikas Makkar, Sudhir Mehta, Suman Sethi, Simran Kaur and P.M. Sohal Introduction: Aki/Acute on Ckd in COVID-19
- Prevalence of Aki in COVID-19
- Pathophysiology of Acute Kidney Injury in COVID-19
- Mechanisms
- Systemic Effects
- Fluid Imbalance
- Congestion of Renal Vein
- Rhabdomyolysis
- Superimposed Infections
- Cytokine Storm
- Pathogenesis of Aki in Crs
- Pro-Inflammatory Cytokines
- Activation-Induced Cell Death
- Activation of Procoagulation Pathways
- Complement System Activation
- Heme-Mediated Pathology
- Systemic Endothelial Injury
- Organ Crosstalk
- Lung-Kidney Axis and Crosstalk
- Mechanism of Lung-Kidney Crosstalk
- Renal Medullary Hypoxia
- Role of Ace2 in the Pathogenesis of Renal Injury
- Site of Ace2 in Lungs/Kidneys
- Entry of Virus into the Cell
- Priming and Role of Tmprss2
- Angiotensin Ii
Author
- Sanjay Kumar Bhadada
- Neeraj Mittal
- Om Prakash Katare
- Varun Garg
