In this issue of Neurosurgery Clinics, guest editors Drs. David D. Limbrick and Jeffrey Leonard bring their considerable expertise to Chiari I Malformation. Top experts in the field cover key topics such as comorbidities associated with Chiari I malformation; orthostatic intolerance and Chiari I malformation; clinical manifestations of Chiari I malformation; imaging in Chiari I malformation; posterior fossa decompression for Chiari I malformation; and more.
Contains 21 relevant, practice-oriented topics sociodemographics of Chiari I malformation; Chiari I malformation and sleep disordered breathing; complex Chiari: diagnosis, evaluation, and treatment; new insights into craniovertebral junction instability in Chiari I malformation; spine deformity associated with Chiari I malformation and syringomyelia; and more.�
Provides in-depth clinical reviews on Chiari I malformation, offering actionable insights for clinical practice.�
Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.�
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Table of Contents
The Nomenclature of Chiari MalformationsEpidemiology of Chiari I Malformation and SyringomyeliaSociodemographics of Chiari I MalformationClinical Manifestations of Chiari I MalformationChiari I Malformation and Sleep-Disordered BreathingOrthostatic Intolerance and Chiari I MalformationElucidating the Genetic Basis of Chiari I MalformationChiari I Malformations and the Heritable Disorders of Connective TissueImaging in Chiari I MalformationCerebrospinal Fluid Hydrodynamics in Chiari I Malformation and Syringomyelia: Modeling PathophysiologyAdult Chiari Malformation Type I: Surgical Anatomy, Microsurgical Technique, and Patient OutcomesPosterior Fossa Decompression with or Without Duraplasty for Chiari I MalformationShort-Term and Long-Term Complications Associated with Posterior Fossa Decompression for Chiari MalformationManagement of Ventral Brainstem Compression in Chiari Malformation Type ICraniovertebral Junction Instability in the Setting of Chiari MalformationComplex Chiari Malformations: Diagnosis, Evaluation, and TreatmentSpine Deformity Associated with Chiari I Malformation and SyringomyeliaRole of Chiari Decompression in Managing Spinal Deformity Associated with Chiari I Malformation and SyringomyeliaAssessing Clinical Outcome Measures in Chiari I MalformationIdiopathic Intracranial Hypertension and Vascular Anomalies in Chiari I MalformationCerebrospinal Fluid Leaks, Spontaneous Intracranial Hypotension, and Chiari I Malformation
Authors
David D. Limbrick Executive Vice-Chair, Department of Neurosurgery, Chief, Division of Pediatric Neurosurgery, Professor of Neurologic Surgery and Pediatrics, Washington University School of Medicine in St. Louis, USA.
David D. Limbrick Jr., MD, PhD is Professor and Chair of Neurosurgery at Virginia Commonwealth University School of Medicine and VCU Health. He holds the James W. and Francis G. McGlothlin Chair in Neurosurgery. His clinical focus is on pediatric brain tumors and innovative surgical methods for brain tumors as they occur across the lifespan. Dr. Limbrick is internationally regarded for his expertise in neuro-endoscopic treatment of intracranial disease and for treating complex disorders of the craniovertebral junction, including the Chiari malformations. He has received the Public Service Citation from the American Association of Neurological Surgeons and Congress of Neurological Surgeons for international neurosurgical relief work, the Humanism in Medicine Award from Washington University School of Medicine, and the Innovator Award from the Hydrocephalus Association. Dr. Limbrick's primary research focus is on cerebrospinal fluid disorders, where he is active in basic, clinical, and translational research. He serves as Principal Investigator for two major multicenter randomized controlled trials: Posterior Fossa Decompression with or without Duraplasty for Chiari Type I Malformation and Syringomyelia and Endoscopic Versus Shunt Treatment of Hydrocephalus in Infants. He is Chair of Biospecimens and Neuro-Imaging for the Hydrocephalus Clinical Research Network and has been the Principal Investigator for the Park-Reeves Syringomyelia Research Consortium since its inception. His research has been continuously funded by NIH, PCORI, and other federal agencies since he joined the faculty in 2008. Most recently, he was the recipient of a program project award (PPG) and an R25 educational grant with a long-term goal of increasing the diversity of the pediatric neurosciences workforce. Dr. Limbrick has authored more than 270 peer-reviewed journal articles and 15 book chapters and has given more than 150 national/international presentations. He has edited two books and serves on the Editorial Board of Journal of Neurosurgery: Pediatrics, Fluids and Barriers of the CNS, and Neurosurgery Practice, where he is the section editor for Pediatric Neurosurgery. He serves as Treasurer of the American Association of Neurological Surgeons (AANS)/Congress of Neurological Surgeons (CNS) Joint Section for Pediatric Neurosurgery, Secretary of the Accreditation Council for Pediatric Neurosurgery Fellowships (ACPNF), and on the Executive Committee of the American Society of Pediatric Neurosurgeons (ASPN). He is a member of the Academy of Neurological Surgeons and the Society of Neurological Surgeons and serves on the National Advisory Committee of the Neurosurgeon Research Career Development Program (NRCDP). Nationally, he serves on the boards of Cure Hydrocephalus, Bobby Jones Chiari & Syringomyelia Foundation, Rudy Schulte Institute, and the Hydrocephalus Association, including the HA Washington Advocacy Committee. Edit
Jeffrey Leonard Chief of Neurosurgery, Nationwide Children's Hospital.
