In 1973, a group of scientists reported that individual genes can be cloned and isolated by cleaving DNA enzymatically into DNA fragments. Over time, gene and DNA cloning has proved to be an important tool for researchers in their studies focused on genetics. The evolution of genetic engineering and cloning techniques has allowed for alterations in the genome of microorganisms, thereby enabling the production of substances having various research and therapeutic applications. Further, cloning can be used to produce gene therapies for the treatment of serious disease indications, such as cystic fibrosis, cancer, AIDS and others. It is interesting to note that gene cloning can be a potential solution to organ scarcity. It also plays an important role in synthesis of antibiotics, vitamins and hormones. Given the various applications of DNA and gene cloning, scientists have taken initiatives for constructing gene libraries having a collection of cloned DNA. However, the process of successful DNA cloning and gene cloning is associated with several challenges and complications, such as gene toxicity, requirement of a specific insert size or large vector, unstable DNA elements, and the presence of DNA secondary structures. In order to overcome these challenges and obtain a high-quality and stable finished product, the outsourcing of DNA and gene cloning is considered as a preferable option, among other alternatives, by companies engaged in DNA and gene cloning.
Currently, several players offer services for DNA cloning and gene cloning. The DNA cloning and gene cloning services market is highly fragmented, featuring presence of various start-ups, mid-sized firms and well-established players. These players offer a wide range of services for DNA and gene cloning with different types of cloning methods. Further, it is worth mentioning that extensive research is being conducted for DNA cloning technologies; this is evident from more than 6,900 research articles that have been published for DNA cloning technologies in the past few years. In addition, more than 35 global events have been organized to discuss about the recent trends related to DNA and gene cloning. Driven by the growing demand for gene therapies, and the introduction and adoption of novel and advanced DNA cloning technologies, the DNA cloning and gene cloning services market is anticipated to witness steady growth in the coming years.
Scope of the Report
The ‘DNA and Gene Cloning Services Market - Distribution by Type of Service Offered (Gene Synthesis, Custom Cloning, Sub-cloning and Others), Type of Gene (Standard Gene, Complex Gene and Others), Company Size (Small, Mid-sized and Large), End-User Industry (Academic and R&D, Pharmaceutical and Biotechnology Companies, and Others) and Key Geographies (North America, Europe, Asia-Pacific, Latin America and MENA): Industry Trends and Global Forecasts, 2022-2035’ report features an extensive study of the current market landscape and future potential of the DNA and gene cloning services market. The study features an in-depth analysis, highlighting the capabilities of DNA cloning and gene cloning service providers.
Amongst other elements, the report features:
- A detailed overview of the overall market landscape of DNA cloning and gene cloning service providers, based on several relevant parameters, such as information on their year of establishment, company size (in terms of employee count), region of headquarters (North America, Europe, Asia-Pacific and rest of the world). In addition to this, the chapter also features information on type of service(s) offered (gene synthesis, custom cloning, sub-cloning and others), cloning method(s) used (Restriction Enzyme Based Cloning, PCR Cloning, Ligation Independent Cloning, TA Cloning, Blunt End Cloning, Seamless Cloning and Recombinational Cloning), type of gene(s) cloned (standard gene and complex gene), expression system(s) used (bacterial, mammalian, insect and yeast), cloning vector(s) used (plasmids, bacteriophages, bacterial artificial chromosomes, yeast artificial chromosomes and mammalian artificial chromosomes) and end-user industry (academic and R&D, pharmaceutical and biotechnology companies, and others).
- An insightful benchmark analysis of the DNA and gene cloning service providers, located in North America, Europe, and Asia-Pacific and Rest of the World. The analysis compares the service providers on the basis of various parameters, such as number of cloning method(s) used, number of expression system(s) used, number of cloning vector(s) used and number of end-user(s). It also highlights the top players in various geographies.
- Elaborate profiles of the key players involved in providing services for DNA and gene cloning. Each profile features a brief overview of the company, its financial information (if available), details on its service portfolio and recent developments with an informed future outlook.
- An in-depth analysis of patents related to DNA and gene cloning, filed / granted since 2017, based on several relevant parameters, such as patent type, publication year, application year, geographical location, Cooperative Patent Classification (CPC) symbols, emerging focus area, type of applicant, leading players (on the basis of number of patents), leading assignees (on the basis of number of patents) and patent benchmarking. In addition, it features a patent valuation analysis which evaluates the qualitative and quantitative aspects of the patents.
- An analysis of more than 6,900 peer-reviewed, scientific articles related to research on DNA and gene cloning, which have been published between 2017 and 2022, including analysis based on parameters, such as year of publication, type of cloning, key focus area, popular journals (in terms of number of articles published in this domain), leading authors (in terms of number of articles published in this domain) and leading first authors (in terms of number of articles published in this domain).
- An in-depth analysis of recent events (conferences / seminars / summits / trainings / webinars / workshops) related to DNA and gene cloning that were organized / planned. It features an analysis based on the year of occurrence of event, event platform, type of event, geographical distribution, emerging agendas / key focus areas, most active event speakers (in terms of number of events), seniority level of event speakers and geographical mapping of the upcoming events.
- A case study on the DNA cloning kits developers, providing information and detailed analysis on kit components, number of reactions, type of cloning method used, type of fragment(s) cloned, cloning time, efficacy and kit shelf life. Further, it also includes a study on the DNA cloning reagents developers, along with a detailed analysis based on reagents’ unit size, concentration, components of reagents, exonuclease activity, product overhangs, heat inactivation temperature and storage temperature. In addition to this, the chapter concludes with the overview of geographical distribution of DNA cloning kits and reagents developers, along with DNA and gene cloning service providers.
One of the key objectives of the report was to evaluate the current opportunity and future potential associated with the DNA and gene cloning services market, over the coming 13 years. We have provided informed estimates of the likely evolution of the market in the short to mid-term and long term, for the period 2022-2035. Our year-wise projections of the current and future opportunity have further been segmented based on relevant parameters, such as [A] type of service offered (gene synthesis, custom cloning, sub-cloning and others), [B] type of gene (standard gene, complex gene and others), [C] company size (small, mid-sized and large), [D] end-user industry (academic and R&D, pharmaceutical and biotechnology companies and others), [E] key geographical regions (North America, Europe, Asia-Pacific, Latin America and MENA). To account for future uncertainties in the market and to add robustness to our model, we have provided three forecast scenarios, portraying the conservative, base and optimistic tracks of the market’s evolution.
The opinions and insights presented in the report were also influenced by discussions held with senior stakeholders in the industry.
Key Questions Answered
- Who are the leading players offering DNA and gene cloning services?
- Which global regions are considered as the hub of DNA cloning kit and reagent developers?
- What is the relative competitiveness of different DNA and gene cloning service providers?
- How has the intellectual property landscape in this field evolved over the years?
- What is the focus of various publications related to DNA and gene cloning?
- What is the key agenda of various global events / conferences related to DNA and gene cloning?
- How is the current and future market opportunity, likely to be distributed across key market segments?
Please note: This report can be updated on request. Please contact our Customer Experience team using the Ask a Question widget on our website.
Table of Contents
Companies Mentioned (Partial List)
A selection of companies mentioned in this report includes, but is not limited to:
- Addgene
- America Diagnostics
- Amid Biosciences
- AMSBIO
- Antibody Research
- Apexigen
- Applied Biological Materials
- Aragen Life Sciences
- Asuragen
- ATUM
- Australian Institute for Bioengineering and Nanotechnology
- Bio Basic
- Biocrede
- Bio-Fab Research
- Biomyx Technology
- Bioneer
- Bionics
- Bio-Serv
- Bioss Antibodies
- Bio-Synthesis
- Bio-Techne
- Brigham and Women’s Hospital (BWH)
- Cambridge Bioscience
- Canvax Biotech
- CD BioSciences
- Cellomics Technology
- Charles River Laboratories
- Cheeky Scientist
- Chromous Biotech
- Cognate BioServices (acquired by Charles River Laboratories)
- Creative Biogene
- Creative Biolabs
- Credora Life Sciences
- Curia (formerly known as AMRI)
- Dana-Farber Cancer Institute
- DNA Cloning Service
- Duke University
- Epoch Life Science
- Blue Heron Biotech (acquired by Eurofins Genomics)
- Eurofins Scientific
- Exonbio
- GCC Biotech
- Gemini Biosciences
- Gene Universal
- GeneCopoeia
- GeneCust
- Genei Laboratories
- geneOmbio Technologies
- General Biosystems
- GENEWIZ (acquired by Azenta Life Sciences)
- Genmab
- Genosphere Biotechnologies
- GenScript
- GW Vitek
- Huazhong University of Science and Technology
- IBA Lifesciences
- Indian Institute of Technology (IIT) Delhi
- Innoprot
- Integrated DNA Technologies
- International Centre for Genetic Engineering and Biotechnology (ICGEB)
- INTOX (acquired by Aragen)
- Janssen Biotech
- Kyowa Kirin
- Labtoo
- LakePharma (acquired by Curia)
- Life Technologies (acquired by Thermo Fischer Scientific)
- LipExoGen Biotech
- Lofstrand Labs
- Luminous BioSciences
- Lundbeck
- Macrogen
- MCLAB
- MedGenome
- Molecular Diagnostic Services
- National Institute for Health and Medical Research (INSERM)
- NKMax
- Light Chain Bioscience (Formerly Novimmune)
- NZYTech
- OriGene Technologies
- Pfizer
- Pharma Explorer
- ProSpec
- Protein Ark
- PurMabiologics
- RD-Biotech
- Rx Biosciences
- Sentebiolab
- Shanghai PharmaExplorer
- Sino Biological
- Stony Brook University (SBU)
- Synbio Technologies
- Syngene
- System Biosciences
- Texas A&M University
- Trenzyme
- Twist Bioscience
- University College London
- University of Arizona
- University of Helsinki
- University of Minnesota
- University of the Philippines Manila
- University of Texas
- Vigene Biosciences (acquired by Charles River Laboratories)
- Virginia Tech Intellectual Properties
- Virovek
- WZ Biosciences
- Zhejiang University
Methodology
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