The digestive enzymes market was valued at $699.4 million in 2021, and is projected to reach $1,643.6 million by 2031, registering a CAGR of 8.7% from 2022 to 2031.
Digestive enzymes break down proteins, carbohydrates, and lipids and their supplementation play a role in management of digestive disorders, from lactose intolerance to cystic fibrosis. Several formulations of digestive enzymes are available in the market, being different from each other in terms of enzyme type, source & origin, and dosage. Animals-derived enzymes represent an established standard of care. However, the growing study of plants-based and microbe-derived enzymes offer great advancements of digestive enzyme therapy. Moreover, pancreatic enzyme supplementation is the therapy of choice for management of exocrine pancreatic insufficiency (EPI) in chronic pancreatitis, pancreatic cancer, cystic fibrosis (CF), or diabetes. Required daily dose of enzymes is variable, being related to etiology and severity of clinical features of patients, such as age & body weight and for cystic fibrosis, genotype and intestinal factors affect absorption.
The digestive enzymes market trends like increase in prevalence of digestive problems, increase in unhealthy lifestyle by population, and rise in geriatric population are key factors that fuel growth of the digestive enzyme market. Moreover, surge in number of fitness centers and gymnasiums has also increased demand for dietary supplements, increase in awareness about GI health, and focus on preventive disease management are other factors that contribute toward growth of the market. However, lack of knowledge regarding appropriate dosage amounts and presence of substitutes for digestive enzyme supplements are expected to hinder growth of the market. Conversely, development of customized digestive enzymes offer lucrative opportunities for growth of the market.
The digestive enzymes market is segmented into origin, enzyme type, application, and region. By origin, the market is categorized into animals, microbial, and plants. Further, the animals segment is categorized into prescription medicine, sports nutrition, and infant nutrition. The sports nutrition segment for animals is classified into sports drink and other sport supplements. Further, the microbial segment is categorized into prescription medicine, sports nutrition, and infant nutrition. In addition, the sports nutrition segment for microbial is classified into sports drink and other sport supplements. The plants segment is further categorized into prescription medicine, sports nutrition, and infant nutrition. The sports nutrition for plants is classified into sports drink and other sport supplements. By enzyme type, the market is divided into carbohydrase, protease, lipase, and others. By application, it is divided into prescription medicine, sports nutrition, and infant nutrition. Region wise, the market is analyzed across North America (U.S., Canada, and Mexico), Europe (Germany, France, UK, Italy, Spain, and rest of Europe), Asia-Pacific (Japan, China, Australia, India, South Korea and Rest of Asia-Pacific), and LAMEA (Brazil, South Africa, Saudi Arabia, and Rest of LAMEA).
Major companies profiled in the report include Abbott Laboratories, AbbVie Inc., Amway Corporation, Archer Daniels Midland Company, Biotics Research Corporation, Brain Group Co Ltd., Country Life, LLC, Douglas Laboratories, Garden of Life, International Flavors & Fragrances Inc, Johnson & Johnson, Metagenics Inc., Mimi's Rock Corporation, Otsuka Holding Co ltd, Soho Flordis International Health, The Enzymedica Group, Vox Nutrition.
Digestive enzymes break down proteins, carbohydrates, and lipids and their supplementation play a role in management of digestive disorders, from lactose intolerance to cystic fibrosis. Several formulations of digestive enzymes are available in the market, being different from each other in terms of enzyme type, source & origin, and dosage. Animals-derived enzymes represent an established standard of care. However, the growing study of plants-based and microbe-derived enzymes offer great advancements of digestive enzyme therapy. Moreover, pancreatic enzyme supplementation is the therapy of choice for management of exocrine pancreatic insufficiency (EPI) in chronic pancreatitis, pancreatic cancer, cystic fibrosis (CF), or diabetes. Required daily dose of enzymes is variable, being related to etiology and severity of clinical features of patients, such as age & body weight and for cystic fibrosis, genotype and intestinal factors affect absorption.
The digestive enzymes market trends like increase in prevalence of digestive problems, increase in unhealthy lifestyle by population, and rise in geriatric population are key factors that fuel growth of the digestive enzyme market. Moreover, surge in number of fitness centers and gymnasiums has also increased demand for dietary supplements, increase in awareness about GI health, and focus on preventive disease management are other factors that contribute toward growth of the market. However, lack of knowledge regarding appropriate dosage amounts and presence of substitutes for digestive enzyme supplements are expected to hinder growth of the market. Conversely, development of customized digestive enzymes offer lucrative opportunities for growth of the market.
The digestive enzymes market is segmented into origin, enzyme type, application, and region. By origin, the market is categorized into animals, microbial, and plants. Further, the animals segment is categorized into prescription medicine, sports nutrition, and infant nutrition. The sports nutrition segment for animals is classified into sports drink and other sport supplements. Further, the microbial segment is categorized into prescription medicine, sports nutrition, and infant nutrition. In addition, the sports nutrition segment for microbial is classified into sports drink and other sport supplements. The plants segment is further categorized into prescription medicine, sports nutrition, and infant nutrition. The sports nutrition for plants is classified into sports drink and other sport supplements. By enzyme type, the market is divided into carbohydrase, protease, lipase, and others. By application, it is divided into prescription medicine, sports nutrition, and infant nutrition. Region wise, the market is analyzed across North America (U.S., Canada, and Mexico), Europe (Germany, France, UK, Italy, Spain, and rest of Europe), Asia-Pacific (Japan, China, Australia, India, South Korea and Rest of Asia-Pacific), and LAMEA (Brazil, South Africa, Saudi Arabia, and Rest of LAMEA).
Major companies profiled in the report include Abbott Laboratories, AbbVie Inc., Amway Corporation, Archer Daniels Midland Company, Biotics Research Corporation, Brain Group Co Ltd., Country Life, LLC, Douglas Laboratories, Garden of Life, International Flavors & Fragrances Inc, Johnson & Johnson, Metagenics Inc., Mimi's Rock Corporation, Otsuka Holding Co ltd, Soho Flordis International Health, The Enzymedica Group, Vox Nutrition.
KEY BENEFITS FOR STAKEHOLDERS
- This report provides a quantitative analysis of the market segments, current trends, estimations, and dynamics of the digestive enzymes market analysis from 2021 to 2031 to identify the prevailing digestive enzymes market opportunities.
- The market research is offered along with information related to key drivers, restraints, and opportunities.
- Porter's five forces analysis highlights the potency of buyers and suppliers to enable stakeholders make profit-oriented business decisions and strengthen their supplier-buyer network.
- In-depth analysis of the digestive enzymes market segmentation assists to determine the prevailing market opportunities.
- Major countries in each region are mapped according to their revenue contribution to the global market.
- Market player positioning facilitates benchmarking and provides a clear understanding of the present position of the market players.
- The report includes the analysis of the regional as well as global digestive enzymes market trends, key players, market segments, application areas, and market growth strategies.
Key Market Segments
By Origin
- Animal
- Microbial
- Plant
By Enzyme Type
- Carbohydrase
- Protease
- Lipase
- Other Enzyme Types
By Applications
- Prescription Medicine
- Sports Nutrition
- Infant Nutrition
By Region
- North America
- U.S.
- Canada
- Mexico
- Europe
- Germany
- France
- U.K.
- Italy
- Spain
- Rest of Europe
- Asia-Pacific
- Japan
- China
- India
- Australia
- South Korea
- Rest of Asia-Pacific
- LAMEA
- Brazil
- Saudi Arabia
- South Africa
- Rest of LAMEA
Key Market Players
- Allergan PLC
- Abbvie Inc.
- Amway Corporation
- Country Life LLC.
- Garden Of Life Inc.
- Biotics Research Corporation
- Metagenics, Inc.
- Abbott Nutrition.
- Johnson & Johnson
- Archer Daniels Midland Company (DeerLand Enzymes)
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Table of Contents
CHAPTER 1: INTRODUCTION
CHAPTER 2: EXECUTIVE SUMMARY
CHAPTER 3: MARKET OVERVIEW
CHAPTER 4: DIGESTIVE ENZYMES MARKET, BY ORIGIN
CHAPTER 5: DIGESTIVE ENZYMES MARKET, BY ENZYME TYPE
CHAPTER 6: DIGESTIVE ENZYMES MARKET, BY APPLICATIONS
CHAPTER 7: DIGESTIVE ENZYMES MARKET, BY REGION
CHAPTER 8: COMPANY LANDSCAPE
CHAPTER 9: COMPANY PROFILES
List of Tables
List of Figures
Executive Summary
According to the report, titled, “Digestive Enzymes Market," the digestive enzymes market size was valued at $699.40 million in 2021, and is estimated to reach $1.64 billion by 2031, growing at a CAGR of 8.7% from 2022 to 2031.Digestive enzymes turn food taken into energy, which may be utilized by the body for various biological processes. Human bodies naturally produce both digestive and metabolic enzymes. Digestive enzymes are protein chemicals, which carry a vital energy factor needed for every chemical action and reaction that occurs in body. Digestive enzymes are secreted along the digestive tract to breakdown food into nutrients and waste. Most digestive enzymes are produced by pancreas. Liver, gallbladder, small intestine, stomach, and colon play pivotal roles in production of these enzymes. Digestive enzymes allow nutrients found in foods consumed to get absorbed into the blood stream and waste to be discarded. Some human digestive enzymes include lipase, protease, amylase, ptyalin, pepsin, and trypsin.
The digestive enzymes market share is expected to experience significant growth during the forecast period, owing to increase in prevalence of digestive problems, increase in unhealthy lifestyle by population, and rise in geriatric population. Moreover, surge in number of fitness centers and gymnasiums has also increased demand for dietary supplements, increase in awareness about GI health, and focus on preventive disease management are other digestive enzymes market trends. However, lack of knowledge about appropriate dosage amounts and presence of substitutes for digestive enzyme supplements are expected to hinder growth of the market. Conversely, development of customized digestive enzymes offer lucrative opportunities in digestive enzymes market growth.
Coronavirus (COVID-19) was discovered in late December in Hubei province of Wuhan city in China. The situation of COVID-19 has varied outcome when related to vaccinations. There is an emerging gap in the economic recovery between high-income and low and middle income countries. After the pandemic severely disrupted global trade, the world is witnessing a robust rebound, which is helping with the recovery in the year 2021. Trade contributes to speeding up economic recovery from the pandemic by providing sustained foreign demand for exports and ensuring the availability of imported intermediate products and services. The COVID-19 pandemic affected the digestive enzymes industry in a fairly negative way, like various other enzyme industries were affected. For instance, according to a review article by Wiley Online Library first published in June 2022, furin is a protease related to coronavirus cell entrance as it is responsible for cleavage of SARS-CoV-2 S protein in lung cells and primary human airway epithelial cells in a transmembrane serine protease-2 (TMPRSS2)-expression dependent manner. However, physiological consequences of inhibiting that enzyme are not known yet. Moreover, according to a study published in the American Journal of Gastroenterology in July 2020, as compared with non-severe COVID-19 patients, severe COVID-19 patients have higher levels of aspartate aminotransferase, alanine aminotransferase, and total bilirubin (TBL).
Overall, the COVID-19 pandemic had a fairly negative impact on the digestive enzymes industry owing to various restrictions imposed on the production and transport of products. However, this situation is expected to change during the forecast period after the pandemic is over.
By origin, the market is categorized into animals, microbial, and plants. The microbial segment dominated the market in 2021, and is anticipated to continue this trend during the forecast period owing to the trends such as rise in demand for microbial enzymes and surge in patient awareness toward effective & advanced technologies. In addition, the microbial segment is also expected to exhibit fastest growth during the forecast period owing to rise in number of cases of digestive disorders leading to the increase in demand of enzymes. Moreover, the launch of effective products, which are tested under clinical trials by the companies that ensure better therapeutic outcomes also contributes to the growth of the market.
By enzyme type, the market is segregated into carbohydrase, protease, lipase, and others. The carbohydrase segment accounted for majority of the market share in 2021, owing to rise in number of products available with carbohydrase enzyme and surge in geriatric population facing digestive problems. Moreover, the protease segment is expected to exhibit fastest growth rate, registering a CAGR of 9.4% from 2022 to 2030, owing to increase in demand for protease-based enzymes in the market.
By application, the market is segregated into prescription medicine, sports nutrition, and infant nutrition. The prescription medicine segment accounted for majority of the market share in 2021, owing to rise in prevalence of digestive disorders leading to rise in use of prescription medicines as supplemental aid and increase in focus on preventive disease management. Moreover, the sports nutrition segment is expected to exhibit fastest growth rate, registering a CAGR of 9.4% during the forecast period, owing to surge in number of fitness centers & gymnasium and increase in awareness about gastrointestinal (GI) health.
North America accounted for the highest revenue in the digestive enzyme market in 2021. The market growth in North America is supplemented by rapid advancements in enzyme products, increase in investments in research & development activities and rise in patient pool. However, Asia-Pacific is expected to emerge as the leading region by registering a CAGR of 9.9% during the forecast period. This is mainly attributed to rise in incidences of digestive disorders such as pancreatitis and pancreatic cancer leading the market growth.
Key Findings of the Study
- By origin, the microbial segment is expected to experience rapid growth in the market, and is projected to grow at a CAGR of 9.3% from 2022 to 2031.
- By enzyme type, the protease segment is projected to grow at a CAGR of 9.4% during the forecast period.
- By application, the sports nutrition segment is projected to grow at a CAGR of 9.4% during the forecast period.
- Region wise, Asia-Pacific is expected to experience growth at the highest rate, registering a CAGR of 9.9% during the forecast period.
Companies Mentioned
- Allergan plc
- Abbvie Inc.
- Amway Corporation
- Country Life LLC.
- Garden of Life Inc.
- Biotics Research Corporation
- Metagenics, Inc.
- Abbott Nutrition.
- Johnson & Johnson
- Archer Daniels Midland Company (Deerland Enzymes)
Methodology
The analyst offers exhaustive research and analysis based on a wide variety of factual inputs, which largely include interviews with industry participants, reliable statistics, and regional intelligence. The in-house industry experts play an instrumental role in designing analytic tools and models, tailored to the requirements of a particular industry segment. The primary research efforts include reaching out participants through mail, tele-conversations, referrals, professional networks, and face-to-face interactions.
They are also in professional corporate relations with various companies that allow them greater flexibility for reaching out to industry participants and commentators for interviews and discussions.
They also refer to a broad array of industry sources for their secondary research, which typically include; however, not limited to:
- Company SEC filings, annual reports, company websites, broker & financial reports, and investor presentations for competitive scenario and shape of the industry
- Scientific and technical writings for product information and related preemptions
- Regional government and statistical databases for macro analysis
- Authentic news articles and other related releases for market evaluation
- Internal and external proprietary databases, key market indicators, and relevant press releases for market estimates and forecast
Furthermore, the accuracy of the data will be analyzed and validated by conducting additional primaries with various industry experts and KOLs. They also provide robust post-sales support to clients.
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Table Information
| Report Attribute | Details |
|---|---|
| No. of Pages | 178 |
| Published | July 2022 |
| Forecast Period | 2021 - 2031 |
| Estimated Market Value ( USD | $ 699.4 million |
| Forecasted Market Value ( USD | $ 1643.6 million |
| Compound Annual Growth Rate | 8.9% |
| Regions Covered | Global |
| No. of Companies Mentioned | 10 |
