The global bone void fillers market was valued at $3,228.4 million in 2021, and is projected to reach $7,330.9 million by 2031, registering a CAGR of 8.5% from 2022 to 2031. Bone void filler is a synthetic bone graft substitute, which is used as filler for bone voids in the bone structure and aims to maintain the stability of bone. A bone void is a complication caused due to failure of the bone’s self-healing process, thus developing cavity in bone. These bone voids or gaps may be surgically generated osseous defects or any bone defect from traumatic injury. Bone void fillers are absorbable, biocompatible, bioactive and osteoconductive biologic materials, which are used to fill gaps of skeletal system such as extremities, pelvis, and posterolateral spine. The biologic material increases cell proliferation and provides stability to bones, which result in enhancement of bone regeneration for multiple types of orthopedic operations.
The growth of the global bone void fillers market is majorly driven by increase in prevalence of bone diseases such as bone tumor & bone infection, rise in geriatric population, increase in number of orthopedic surgeries, and surge in cases of sports injuries & accidents. Moreover, increase in R&D activities in the healthcare sector and rise in demand for synthetic bone void filler drive the growth of the market. In addition, the widespread use of bone void fillers in the dentistry sector is anticipated to contribute toward the market growth. Increase in prevalence of bone diseases leads to increase in the number of orthopedic surgeries, which further fosters the market growth. For instance, according to the report shared by the International Osteoporosis Foundation (IOF), estimated change in the annual number of osteoporotic fractures from 2019 to 2034 is 24.8%, which will reach to 5.34 million in 2034 from 4.3 million in 2019.
Furthermore, increase in the number of spinal fusions, arthroplasty procedures, and oral surgeries boosts the growth of the bone void fillers market. Moreover, chronic orthopedic diseases require surgeries such as hip and knee replacements. In such surgeries, bone void fillers are used to fill the gaps in bone. Therefore, increase in number of knee replacement surgeries fuels the market growth. For instance, in Canada, the knee and hip replacement surgery is the second most common surgery, as per the report shared by the Canadian Joint Replacement Registry (CJRR). Approximately more than 75,000 knee replacement and 63,000 hip replacement surgeries were performed in Canada from 2019 to 2020. This report further states 2.4% increase in the hip replacement surgery from 2019 to 2020.
On the contrary, low penetration and clinical barriers of bone void fillers are anticipated to hinder the bone void fillers market growth. Moreover, high cost of surgery is anticipated to act as a major restraint of the global market.
Increase in number of key players that focus on launching different forms of bone void fillers and rise in medical tourism support the market growth. Furthermore, people are travelling across the world to get their treatment done at affordable prices. Despite the affordability, people tend to believe not to compromise on the quality of life. Thus, increase in number of specialized hospitals in countries such as Singapore, Japan, China, and India provide good treatment at affordable price, which encourage patients to travel across the world.
The global bone void fillers market is segmented into type, form, application, end user, and region. By type, the market is segregated into demineralized bone matrix, calcium phosphate bone graft substitute, collagen matrix, and others. The others segment includes magnesium bone graft substitution and calcium sulfate bone void filler. On the basis of form, the market is categorized into gel & putty, granules, and others. The others segment includes paste, powder, and liquid. Depending on application, the market is fragmented into spine fusion, bone fracture, and others. The others segment include pelvic surgery and oral surgery. As per end user, the market is differentiated into hospital, specialty clinics, and others. The others segment includes research centers and specialty clinics.
Region wise, is the market is analyzed across North America, Europe, Asia-Pacific, and LAMEA.
Some of the major companies that operate in the bone void fillers market are Arthrex Inc., Baxter International Companies, DePuy Synthes Companies, Medtronic Plc., NuVasive Inc. Orthofix Medical Inc., Smith and Nephew Plc., Stryker Corporation, Wright Medical Group Inc., and Zimmer Biomet.
The market research is offered along with information related to key drivers, restraints, and opportunities.
Porter's five forces analysis highlights the potency of buyers and suppliers to enable stakeholders make profit-oriented business decisions and strengthen their supplier-buyer network.
In-depth analysis of the bone void fillers market segmentation assists to determine the prevailing market opportunities.
Major countries in each region are mapped according to their revenue contribution to the global market.
Market player positioning facilitates benchmarking and provides a clear understanding of the present position of the market players.
The report includes the analysis of the regional as well as global bone void fillers market trends, key players, market segments, application areas, and market growth strategies.
The growth of the global bone void fillers market is majorly driven by increase in prevalence of bone diseases such as bone tumor & bone infection, rise in geriatric population, increase in number of orthopedic surgeries, and surge in cases of sports injuries & accidents. Moreover, increase in R&D activities in the healthcare sector and rise in demand for synthetic bone void filler drive the growth of the market. In addition, the widespread use of bone void fillers in the dentistry sector is anticipated to contribute toward the market growth. Increase in prevalence of bone diseases leads to increase in the number of orthopedic surgeries, which further fosters the market growth. For instance, according to the report shared by the International Osteoporosis Foundation (IOF), estimated change in the annual number of osteoporotic fractures from 2019 to 2034 is 24.8%, which will reach to 5.34 million in 2034 from 4.3 million in 2019.
Furthermore, increase in the number of spinal fusions, arthroplasty procedures, and oral surgeries boosts the growth of the bone void fillers market. Moreover, chronic orthopedic diseases require surgeries such as hip and knee replacements. In such surgeries, bone void fillers are used to fill the gaps in bone. Therefore, increase in number of knee replacement surgeries fuels the market growth. For instance, in Canada, the knee and hip replacement surgery is the second most common surgery, as per the report shared by the Canadian Joint Replacement Registry (CJRR). Approximately more than 75,000 knee replacement and 63,000 hip replacement surgeries were performed in Canada from 2019 to 2020. This report further states 2.4% increase in the hip replacement surgery from 2019 to 2020.
On the contrary, low penetration and clinical barriers of bone void fillers are anticipated to hinder the bone void fillers market growth. Moreover, high cost of surgery is anticipated to act as a major restraint of the global market.
Increase in number of key players that focus on launching different forms of bone void fillers and rise in medical tourism support the market growth. Furthermore, people are travelling across the world to get their treatment done at affordable prices. Despite the affordability, people tend to believe not to compromise on the quality of life. Thus, increase in number of specialized hospitals in countries such as Singapore, Japan, China, and India provide good treatment at affordable price, which encourage patients to travel across the world.
The global bone void fillers market is segmented into type, form, application, end user, and region. By type, the market is segregated into demineralized bone matrix, calcium phosphate bone graft substitute, collagen matrix, and others. The others segment includes magnesium bone graft substitution and calcium sulfate bone void filler. On the basis of form, the market is categorized into gel & putty, granules, and others. The others segment includes paste, powder, and liquid. Depending on application, the market is fragmented into spine fusion, bone fracture, and others. The others segment include pelvic surgery and oral surgery. As per end user, the market is differentiated into hospital, specialty clinics, and others. The others segment includes research centers and specialty clinics.
Region wise, is the market is analyzed across North America, Europe, Asia-Pacific, and LAMEA.
Some of the major companies that operate in the bone void fillers market are Arthrex Inc., Baxter International Companies, DePuy Synthes Companies, Medtronic Plc., NuVasive Inc. Orthofix Medical Inc., Smith and Nephew Plc., Stryker Corporation, Wright Medical Group Inc., and Zimmer Biomet.
KEY BENEFITS FOR STAKEHOLDERS
This report provides a quantitative analysis of the market segments, current trends, estimations, and dynamics of the bone void fillers market analysis from 2021 to 2031 to identify the prevailing bone void fillers market opportunities.The market research is offered along with information related to key drivers, restraints, and opportunities.
Porter's five forces analysis highlights the potency of buyers and suppliers to enable stakeholders make profit-oriented business decisions and strengthen their supplier-buyer network.
In-depth analysis of the bone void fillers market segmentation assists to determine the prevailing market opportunities.
Major countries in each region are mapped according to their revenue contribution to the global market.
Market player positioning facilitates benchmarking and provides a clear understanding of the present position of the market players.
The report includes the analysis of the regional as well as global bone void fillers market trends, key players, market segments, application areas, and market growth strategies.
Key Market Segments
By Type
- Demineralized bone matrix
- Calcium phosphate bone graft substitute
- Collagen Matrix
- Others
By Form
- Gel and Putty
- Granules
- Others
By Application
- Spine fusion
- Bone fracture
- Others
By End User
- Hospital
- Specialty Clinics
- Others
By Region
- North America
- U.S.
- Canada
- Mexico
- Europe
- Germany
- France
- U.K.
- Italy
- Spain
- Rest of Europe
- Asia-Pacific
- China
- Japan
- India
- Australia
- South Korea
- Rest of Asia-Pacific
- LAMEA
- Brazil
- Saudi Arabia
- South Africa
- Rest of LAMEA
Key Market Players
- Arthrex Inc
- Baxter International Inc.
- depuy synthes companies
- Medtronic plc
- NuVasive Inc
- Orthofix Medical Inc
- Smith and Nephew plc
- Stryker Corporation
- Wright Medical Group Inc
- Zimmer Biomet
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Table of Contents
CHAPTER 1: INTRODUCTION
CHAPTER 2: EXECUTIVE SUMMARY
CHAPTER 3: MARKET OVERVIEW
CHAPTER 4: BONE VOID FILLERS MARKET, BY TYPE
CHAPTER 5: BONE VOID FILLERS MARKET, BY FORM
CHAPTER 6: BONE VOID FILLERS MARKET, BY APPLICATION
CHAPTER 7: BONE VOID FILLERS MARKET, BY END USER
CHAPTER 8: BONE VOID FILLERS MARKET, BY REGION
CHAPTER 9: COMPANY LANDSCAPE
CHAPTER 10: COMPANY PROFILES
List of Tables
List of Figures
Executive Summary
According to the report, titled, “Bone Void Fillers Market," the bone void fillers market size was valued at $3.2 billion in 2021, and is estimated to reach $7.3 billion by 2031, growing at a CAGR of 8.5% from 2022 to 2031. Bone void is cavity or gap in the bone, which is caused due to failure of the bone’s self-healing process. Bone void fillers are used in a wide range of indications such as orthopedic surgery, spinal fusion, dental surgery, oral surgery, and interbody fusion. Bone void filler is a synthetic substitute, which is used to fill the gaps or void in the bones. It provides stability to bone structure. The bone void substitute is used for surgical procedures such as spine fusion, bone fracture, pelvic surgery, and oral surgery. Bone void fillers come in different types such as demineralized bone matrix, calcium phosphate bone graft substitute,and collagen matrix. These fillers are available in different forms such as powder, paste, gel, granules, and putty.Factors that drive growth of the bone void fillers market size are rise in incidence of fracture & accidents, rise in geriatric population, increase in inclination of patients toward minimally invasive & non-invasive surgical treatments, surge in demand for antibiotic eluting bone void fillers, rise in number of bone graft procedures, and surge in patient awareness toward use of bone void fillers among physicians & surgeons. In addition, increase in prevalence of bone & spinal diseases and procedural benefits provided by bone void fillers in bone fracture treatment and orthopedic diseases boost the bone void fillers market trends.
Furthermore, surge in number of aged individuals who are more prone to undergo orthopedic surgeries, as aged population is highly susceptible to fractures and bone injuries notably contributes toward the bone void fillers market analysis. For instance, according to the World Health Organization (WHO), in October 2021, by 2030, 1 in 6 people in the world will be aged 60 years or over. Moreover, according to the Journal of JAMA Network Open, in 2021, about 32% of surgical procedures in the U.S. were conducted among patients aged more than 65 years.
Increase in the number of anterior cervical discectomies and fusions procedures by bone void fillers industry further propels the market growth. For instance, according to a report published by World Neurosurgery, in 2020, there were 153,288 anterior cervical discectomy and fusions performed in the U.S. As per the same report, the number of surgeries is estimated to increase by 13.3% by 2040. Moreover, rise in in the number of bone void fillers industry launching bone void fillers products fuels the growth of bone void fillers market. For instance, in January 2022, Bone Solution Inc., an ortho-biologics technology company, announced the launch of Mg OSTEOINJECT, an injectable magnesium-based bone void filler.
The global bone void fillers market is segmented into type, form, application, end user, and region.
On the basis of type, the market is classified into demineralized bone matrix, calcium phosphate bone graft substitute, collagen matrix, and others segment. The demineralized bone matrix segment dominated the market in 2021, and is expected to continue this trend during the bone void fillers market forecast period, owing to increase in the use for dental implants and orthopedic surgery.
Depending on form, the market is segregated into gel & putty, granules, and others segment. The gel & putty segment exhibited the highest growth in 2021, and is anticipated to lead in the coming future, owing to increase in the number of non-invasive and minimally invasive surgeries.
By application, the market is fragmented into spine fusion, bone fracture, and others segment. Bone fracture was the prominent segment in 2021, and is expected to continue this trend during the forecast period, owing to increase in prevalence of osteoporosis, rise in geriatric population, and surge in cases of sport injuries & accidents.
As per end user, the market is differentiated into hospital, specialty clinics, and others. The hospital segment led the market in 2021, and is expected to continue this trend during the forecast period, owing to increase in initiatives taken by government to develop healthcare infrastructure and rise in number of hospitals & clinics.
North America accounted for a majority of the global bone void fillers market share in 2021, and is anticipated to remain dominant during the forecast period. This is attributed to higher adoption of synthetic bone void fillers, large presence of medical device companies, availability of well-developed healthcare infrastructure, and wide availability of bone void fillers. However, Asia-Pacific is anticipated to witness lucrative growth in the future, owing to increase in prevalence of orthopedic diseases, rise in awareness about the use of bone void fillers, surge in healthcare expenditure, and increase in geriatric population.
The COVID-19 outbreak is anticipated to have a negative impact on growth of the global bone void fillers market. During the COVID-19 pandemic period, stringent regulations were implemented by local and national governments on the delivery of products from companies. Increase in number of COVID-19 cases led to decline in the number of surgical procedures. The COVID-19 pandemic has stressed the healthcare systems in the world and increased the need for the development of novel therapeutics. For instance, according to report shared by the National Center for Biotechnology Information (NCBI) in June 2021, the number of patients visit for surgeries decreased from 74.2 % to 37.7% and decrease in the orthopedic surgeries by 33.3% to 100%. Moreover, due to COVID-19 restrictions, market players witnessed significant decline in revenue generated during COVID-19. Thus, cancellations of non-emergency surgeries during the pandemic affected the growth of bone void fillers market. On the contrary, the number of surgical procedures is expected to grow gradually post the pandemic. According to the Journal of Cureus, in 2022, it was analyzed that the number of cervical spinal fusion procedures increased by 44.9% from 2020 to 2021. Thus, increase in number of cervical spine fusion procedures after pandemic fostered the use of bone void fillers products. Hence, increase in the number of orthopedic surgical procedures propels the demand for bone void fillers, which fuels the market growth.
Key Findings of the Study
- By type, the demineralized bone matrix segment was the highest contributor to the market in 2021.
- On the basis of form, gel & putty segment led the market in 2021.
- Depending on application, the bone fracture segment exhibited the highest growth in 2021, and is expected to continue this trend during the forecast period.
- As per end user, the hospital segment dominated the market in 2021.
- Region wise, North America garnered the largest revenue share in 2021, whereas Asia-Pacific is anticipated to grow at the highest CAGR during the forecast period.
Companies Mentioned
- Arthrex Inc
- Baxter International Inc.
- Depuy Synthes Companies
- Medtronic plc
- Nuvasive Inc
- Orthofix Medical Inc
- Smith and Nephew plc
- Stryker Corporation
- Wright Medical Group Inc
- Zimmer Biomet
Methodology
The analyst offers exhaustive research and analysis based on a wide variety of factual inputs, which largely include interviews with industry participants, reliable statistics, and regional intelligence. The in-house industry experts play an instrumental role in designing analytic tools and models, tailored to the requirements of a particular industry segment. The primary research efforts include reaching out participants through mail, tele-conversations, referrals, professional networks, and face-to-face interactions.
They are also in professional corporate relations with various companies that allow them greater flexibility for reaching out to industry participants and commentators for interviews and discussions.
They also refer to a broad array of industry sources for their secondary research, which typically include; however, not limited to:
- Company SEC filings, annual reports, company websites, broker & financial reports, and investor presentations for competitive scenario and shape of the industry
- Scientific and technical writings for product information and related preemptions
- Regional government and statistical databases for macro analysis
- Authentic news articles and other related releases for market evaluation
- Internal and external proprietary databases, key market indicators, and relevant press releases for market estimates and forecast
Furthermore, the accuracy of the data will be analyzed and validated by conducting additional primaries with various industry experts and KOLs. They also provide robust post-sales support to clients.
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Table Information
| Report Attribute | Details |
|---|---|
| No. of Pages | 303 |
| Published | June 2022 |
| Forecast Period | 2021 - 2031 |
| Estimated Market Value ( USD | $ 3228.4 million |
| Forecasted Market Value ( USD | $ 7330.9 million |
| Compound Annual Growth Rate | 8.5% |
| Regions Covered | Global |
| No. of Companies Mentioned | 10 |
