The Asia Pacific Synthetic Small Molecule API Market would witness market growth of 6.0% CAGR during the forecast period (2022-2028).
A technique called gas-phase hydrogen-deuterium exchange in conjunction with ion mobility spectrometry-mass spectrometry (IMS-MS) has been used to analyze novel psychoactive substances (NPSs), which are tiny synthetic chemicals created to mimic the effects of other illegal narcotics. Here, the HDX reactivity of NPSs with labile heteroatom hydrogens was assessed in the drift tube with either deuterated water (D2O) or ammonia (ND3). Six NPSs underwent a preliminary study of exchange propensity.
In the presence of ND3, five compounds were exchanged, but only one NPS (benzyl piperazine) was transferred with D2O. The diamine ring of benzyl piperazine offered this charging site at a set length since the exchange mechanism of D2O needs stabilization with a neighboring charged site. O, M, and P-fluorophenyl piperazine, three disubstituted benzene isomers, contain the diamine.
These isomers could not be differentiated from one another by IMS-MS alone due to their same isotopic content and nearly identical drift time distributions. A test of means following HDX in the drift tube, however, revealed that differentiation was feasible if the exchange data from both reagent gases were considered. The observed exchange disparities may partially be explained by the fact that molecular dynamics simulations reveal that the fluorine's proximity to the diamine ring prevents the benzene and diamine ring from rotating at the same dihedral angle.
The market for molecular quality controls is in good shape as a result of the consistently growing demand for accurate and high-quality diagnostic tests. The need for precision oncology has become a prominent focus of various authorities in the region, leading to the formation of multiple projects, as cancer is becoming a more prevalent health issue in the APAC region as a result of aging populations and lifestyle changes. These programs include the Japanese LC-SCRUM lung cancer genomic screening project and the South Korean K-MASTER (Korean Cancer Precision Medicine Diagnosis and Treatment Enterprise) platform.
The China market dominated the Asia Pacific Synthetic Small Molecule API Market by Country in 2021; thereby, achieving a market value of $14,660.4 million by 2028. The Japan market is experiencing a CAGR of 5.3% during (2022-2028). Additionally, The India market is exhibiting a CAGR of 6.6% during (2022-2028).
Based on Manufacturer, the market is segmented into In-house and Outsourced. Based on Application, the market is segmented into Cardiology, Oncology, CNS & Neurology, Endocrinology, Orthopedic, Gastroenterology, Pulmonology, Nephrology, Ophthalmology, and Others. Based on countries, the market is segmented into China, Japan, India, South Korea, Singapore, Malaysia, and Rest of Asia Pacific.
The market research report covers the analysis of key stake holders of the market. Key companies profiled in the report include Merck & Co., Inc., Viatris, Inc., Cipla Limited, Teva Pharmaceuticals Industries Ltd., Sun Pharmaceuticals Industries Ltd., AbbVie, Inc., Bristol Myers Squibb Company, Boehringer Ingelheim International GmbH, Aurobindo Pharma Limited and Albermale Corporation.
A technique called gas-phase hydrogen-deuterium exchange in conjunction with ion mobility spectrometry-mass spectrometry (IMS-MS) has been used to analyze novel psychoactive substances (NPSs), which are tiny synthetic chemicals created to mimic the effects of other illegal narcotics. Here, the HDX reactivity of NPSs with labile heteroatom hydrogens was assessed in the drift tube with either deuterated water (D2O) or ammonia (ND3). Six NPSs underwent a preliminary study of exchange propensity.
In the presence of ND3, five compounds were exchanged, but only one NPS (benzyl piperazine) was transferred with D2O. The diamine ring of benzyl piperazine offered this charging site at a set length since the exchange mechanism of D2O needs stabilization with a neighboring charged site. O, M, and P-fluorophenyl piperazine, three disubstituted benzene isomers, contain the diamine.
These isomers could not be differentiated from one another by IMS-MS alone due to their same isotopic content and nearly identical drift time distributions. A test of means following HDX in the drift tube, however, revealed that differentiation was feasible if the exchange data from both reagent gases were considered. The observed exchange disparities may partially be explained by the fact that molecular dynamics simulations reveal that the fluorine's proximity to the diamine ring prevents the benzene and diamine ring from rotating at the same dihedral angle.
The market for molecular quality controls is in good shape as a result of the consistently growing demand for accurate and high-quality diagnostic tests. The need for precision oncology has become a prominent focus of various authorities in the region, leading to the formation of multiple projects, as cancer is becoming a more prevalent health issue in the APAC region as a result of aging populations and lifestyle changes. These programs include the Japanese LC-SCRUM lung cancer genomic screening project and the South Korean K-MASTER (Korean Cancer Precision Medicine Diagnosis and Treatment Enterprise) platform.
The China market dominated the Asia Pacific Synthetic Small Molecule API Market by Country in 2021; thereby, achieving a market value of $14,660.4 million by 2028. The Japan market is experiencing a CAGR of 5.3% during (2022-2028). Additionally, The India market is exhibiting a CAGR of 6.6% during (2022-2028).
Based on Manufacturer, the market is segmented into In-house and Outsourced. Based on Application, the market is segmented into Cardiology, Oncology, CNS & Neurology, Endocrinology, Orthopedic, Gastroenterology, Pulmonology, Nephrology, Ophthalmology, and Others. Based on countries, the market is segmented into China, Japan, India, South Korea, Singapore, Malaysia, and Rest of Asia Pacific.
The market research report covers the analysis of key stake holders of the market. Key companies profiled in the report include Merck & Co., Inc., Viatris, Inc., Cipla Limited, Teva Pharmaceuticals Industries Ltd., Sun Pharmaceuticals Industries Ltd., AbbVie, Inc., Bristol Myers Squibb Company, Boehringer Ingelheim International GmbH, Aurobindo Pharma Limited and Albermale Corporation.
Scope of the Study
Market Segments Covered in the Report:
By Manufacturer
- In-house
- Outsourced
By Application
- Cardiology
- Oncology
- CNS & Neurology
- Endocrinology
- Orthopedic
- Gastroenterology
- Pulmonology
- Nephrology
- Ophthalmology
- Others
By Country
- China
- Japan
- India
- South Korea
- Singapore
- Malaysia
- Rest of Asia Pacific
Key Market Players
List of Companies Profiled in the Report:
- Merck & Co., Inc.
- Viatris, Inc.
- Cipla Limited
- Teva Pharmaceuticals Industries Ltd.
- Sun Pharmaceuticals Industries Ltd.
- AbbVie, Inc.
- Bristol Myers Squibb Company
- Boehringer Ingelheim International GmbH
- Aurobindo Pharma Limited
- Albermale Corporation
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Table of Contents
Chapter 1. Market Scope & Methodology
Chapter 2. Market Overview
Chapter 3. Asia Pacific Synthetic Small Molecule API Market by Manufacturer
Chapter 4. Asia Pacific Synthetic Small Molecule API Market by Application
Chapter 5. Asia Pacific Synthetic Small Molecule API Market by Country
Chapter 6. Company Profiles
Companies Mentioned
- Merck & Co., Inc.
- Viatris, Inc.
- Cipla Limited
- Teva Pharmaceuticals Industries Ltd.
- Sun Pharmaceuticals Industries Ltd.
- AbbVie, Inc.
- Bristol Myers Squibb Company
- Boehringer Ingelheim International GmbH
- Aurobindo Pharma Limited
- Albermale Corporation
Methodology
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