More than 10,000 unique species of microorganisms make up the human microbiome; in fact, the total number of microbial cells in the human body is known to vastly outnumber the indigenous cellular population. Of late, many studies have demonstrated the importance of microbiome and its profound influence on multiple biological functions. Moreover, it has been shown that the diversity of the microbial community residing in a host body varies based on both intrinsic (gender, genetics, and immunity) and extrinsic factors (diet and geographical location). Modern bioanalytical techniques have enabled researchers to delve deeper into microbiome research, in terms of species identity and the influence of specific genera on various tissues and organs in the human body. Leveraging this information, advanced genome sequencing technologies and meta-analyses have allowed scientists to build unique profiles of human subjects (including both healthy individuals and patients) based on the microbial flora residing in their respective bodies. Further, imbalances in the microbiota, also known as dysbiosis, have been proven to be associated with several known diseases, including (but not limited to) cancer, diabetes, inflammatory bowel diseases, autism, anxiety and obesity. This data is presently being used in the diagnosis and treatment of more than 25 clinical conditions, by restoring key bacterial populations in the body. Experts also believe it possible that there are additional microbial species within the human microbiome, which are yet to be discovered.
In the above context, several microbiome drugs based on replenishing / restoring the microbiota in specific anatomical locations, have been developed (such as fecal microbiota transplant) and many such therapy candidates are under development. Such targeted manipulations of the microbiome represent a rapidly advancing area of clinical research. An analysis of published scientific research revealed that the count of articles focused on the therapeutic manipulation of the human microbiome has grown at a rate of over 2,000%, since 2005. However, there is still a lot, such as the functional links (at a mechanistic level) between the gut bacteria and disease, to be understood in this direction. It is worth noting that the intellectual capital, including compositions of live biotherapeutic products and associated methods of use, related to this upcoming class of therapeutics has also grown. Researchers believe that, in the future, the microbiome can be engineered for use as a controlled delivery system for conventional drugs / therapies. Transgene modified bacteria can even be used to trigger internal molecular circuits in order to regulate the production of therapeutic proteins, based on the expression of specific disease biomarkers, thereby, enabling on-demand release (or expression) of therapeutic secondary metabolites / biomolecules. In light of such developments, it is important to keep track of both the pockets of innovation and key areas of improvement for stakeholders to remain competitive in this upcoming field of medicine. This report captures some of the key R&D-related trends and provides competitive intelligence on intellectual property, in the field of microbiome therapeutics and diagnostics.
Scope of the Report
The “Microbiome Therapeutics: Intellectual Property Landscape” report features an extensive study of some of the key historical and contemporary intellectual property (IP) documents (featuring granted patents, patent applications and other documents), describing the various types of microbiome-based interventions intended to treat a growing range of clinical conditions. Fundamentally, these are live biotherapeutic products, which have recently been proven to have the potential to aid in the amelioration of several diseases, primarily via the gut-brain axis. The insights generated in this report have been presented across two deliverables, namely a MS Excel workbook and a MS PowerPoint deck, summarizing the ongoing activity in this domain. Key inclusions are briefly described below:
Overall Intellectual Property Landscape
An analytical perspective of the various patents and affiliated IP documents that have been published related to microbiome-based therapies and diagnostics, since 1969. An in-depth analysis of published IP documents, representing unique patent families across various global jurisdictions, featuring insightful inferences related to both historical and recent R&D trends within this niche, but rapidly evolving segment of the pharmaceutical industry.
Popular / Relevant Prior Art Search Expressions
An examination of IP literature, shortlisting key words and phrases used to describe microbiome-based therapies (and affiliated products) that are either already available in the market, or under development. The analysis also includes details on the historical use of the aforementioned terms across different IP filings, key affiliated terms (which can be used to identify other relevant IP search terms and establish relationships between prior art search expressions), and other related trends.
Patent Valuation Analysis
A competitive benchmarking and valuation analysis of the key members of unique patent families captured in the report, taking into consideration important parameters, such as type of IP document, year of application, time to expiry, number of citations and jurisdiction (factoring in value associated with the gross domestic product (GDP) of a particular region).
Patentability and Freedom to Operate
A systematic approach to identifying relevant areas of innovation by analyzing published IP documents (representative of unique patent families), by defining the uniqueness of patented / patent pending innovations, in order to assess the scope of patentability in this domain, and pinpoint jurisdictions wherein new and / or modified claims may be filed without infringing on existing IP.
Analysis of Patent Applications
A detailed summary of the various patent applications (representative of unique patent families) that were filed across different jurisdictions and their relative value in the IP ecosystem. The analysis classified the intellectual capital in terms of type of innovation and the specific innovation (such as a product class, enabling technologies or method of use), thereby, offering the means to identify active arenas of research and assess innovation-specific IP filing trends.
Analysis of Granted Patents
An analysis of the granted patents (representative of unique patent families) across different global jurisdictions and their relative value in the IP ecosystem. The analysis also features a meaningful classification system, segregating granted IP into relevant categories (namely type of innovation and innovation) to help develop a detailed perspective on the diversity of intellectual capital (having marketing exclusivity) related to microbiome therapeutics and diagnostics, and the assessing likelihood for innovators to enter into promising product markets.
Pockets of Innovation and White Spaces
An insightful analysis of the various CPC codes used in published IP literature (representative of unique patent families) and their affiliated families, offering the means to identify historical and existing pockets of innovation (based on the functional area / industry described by the elaborate and systematic IP classification approach, mentioned earlier); the analysis also features a discussion on prevalent white spaces (based on CPC symbols) in this field of research.
Claims Analysis
One of the objectives of the report was to analyze and summarize key inferences from the independent claims mentioned in granted, active patents (representative of unique patent families) in the dataset. Using a systematic segregation approach, we have analyzed trends associated with the preamble, type of patent (product patent or method patent), type of claim (open ended claim or closed ended claim) and key elements of a claim (individual aspects of an innovation that are covered in a singular claim).
Table of Contents
Excel Deliverable1. Research Notes
Companies Mentioned (Partial List)
A selection of companies mentioned in this report includes, but is not limited to:
- 10x Genomics
- 10X Technologies
- 3BIGS
- 4D Molecular Therapeutics
- 4D Pharma
- 4Life Patents
- 7wire Ventures
- A & PEP
- A&G Biomedical
- AB-Biotics
- ABB automation
- Abbio
- AbbVie
- ABB
- AbCelex Technologies
- Aber
- ABR Consulting
- Acacia-no-ki
- Accelerate Diagnostics
- Access Business Group
- ACEA Biosciences
- Achim Biotherapeutics
- Actym Therapeutics
- Aduro Biotech
- Advagene Biopharma
- Advanced Biological Marketing
- Advaxis
- Adventia
- Aeterna Zentaris
- AGC
- AGC Si-Tech
- AgraQuest
- Agricam
- Akita Konno
- Albert Einstein College of Medicine
- Albion
- Alcatel-Lucent
- Alchemy Biosciences
- Alexion
- AlfaGene Bioscience
- Alimentary Health
- ALK
- Allelix
- Allergan
- Alpha MED Scientific
- Amano Enzyme
- Ambi
- Amersham
- Amrita Therapeutics
- AmtixBio
- Amucin Oy
- Amyris
- Anadis
- Anaeropharma Science
- Anagenix
- Anallergo
- Ancera
- Ancilia
- Anhui Fuming Supply Chain Management
- AnimalBiome
- Anpac Bio-Medical Science
- Antenna
- Anti-Cancer Drugs
- AOBiome
- AOF
- Aram
- Arivale
- Arkray
- Artizan Biosciences
- Artugen Therapeutics
- Asahi Breweries
- Asahi Group Holdings
- Ascus Biosciences
- Ashutosh Mangalam
- Ashwin N Ananthakrishnan
- Asia-Pacific Biotech Developing
- Asia-Pacific biotechnology
- Asis Datta
- ASL Analytical
- ASPECT AI
- Assembly Biosciences
- Assistance Publique-Hôpitaux de Paris
- Asterias Biotherapeutics
- Atheromastat
- Atlas Biomed
- Atogen
- Atterx Biotherapeutics
- Aureo
- Aurora Biofuels
- Avisa Pharma
- Axcella Health
- Axcess Global
- Axial Biotherapeutics
- Azitra
- B.G. Negev Technologies and Applications
- Bactest
- Baikalian Research Centre
- Baker Company
- BASF
- Batavia
- Bausch Health
- Bayer
- Bayer CropScience
- Behringwerke
- Beiersdorf
- Beijing Libeier Bio-engineering Institute
- Beijing Scitop Bio-tech
- Beijing Smistyle Sci. & Tech. Development
- Beijing Taisheng Biological Technology
- Beijing Wangsheng Weiye Sci. Development
- Beijing Zhongjian Antai Diagnostic Technology
- Beijing Zhongkang Wanda Pharmaceutical Technology
- Bell Biosystems
- Berkeley Lights
- Beta Pharma
- Beth Israel Deaconess Medical Center
- BGI
- bifido
- BiNAARE
- BINEX
- Bio Agens Research and Development
- Bio Foods (a subsidiary of LT Foods Ltd)
- Bio Lab
- Bio Seek
- Bio-K+
- Biobank Healing
- BioChem Technology
- BioChemTech
- Biocodex
- BioConsortia
- Biocontrol
- Biocontrol System
- BioDiscovery New Zealand
- Bioeos
- Biofermin Pharmaceutical
- BioGaia
- Biogenics
- BioGrowing
- Biolog
- Biologics (AIM-Bio)
- Biomanagement Systems
- Biomay
- Biome Health
- Biome Makers
- BioMed Valley Discoveries
- Biomics
- BiomX
- bioMérieux
- Bionet
- Bioniche Life Science
- Bioniche Life Sciences
- Bion
- BioPlx
- BioProtein AS
- Bioresource Technology
- Bioscal
- Biosense Technologies
- BIOSTAR
- Biosynth
- Biota
- bitBiome
- Blaze Medical Devices
- BLIS
- BlueGreen Biotech
- Board of Supervisors
- Boehringer Ingelheim
- Botulinum toxin
- Brigham and Women's Hospital
- Bright Dairy & Food
- BrightPath Biotherapeutics
- Broad Institute
- Bruker
- Bruno Lange
- BTF Pty
- Bürkert
- C3 Jian
- Cadila Pharmaceuticals
- Calidi Biotherapeutics
- California Institute for Regenerative Medicine
- California Institute of Technology
- Calpis
- Cambrian
- Cambridge Enterprises
- CapitalBio Genomics
- Capitis Equities
- Carbiotix
- Cargill
- Cargill Dow
- CARNEGIE VENTURE CAPITAL
- Cavit Sciences
- CBD and technology
- CDI Laboratories
- Celina Maria Monteiro
- CELL ACTIVATION RESEARCH INSTITUTE
- Cell Biotech
- Cell Technology
- Cell-Tech
- Cell2in
- Cellectricon
- Cellex
- Celula
- Cemvita Factory
- Centocor Ortho Biotech
- Central Glass
- Centro de Bioactivos Químicos
- Cerner
- Cerule
- Chan Zuckerberg Biohub
- Changsha Xingjia Bio-Engineering
- Charm Sciences
- CheBiGen
- Chemical dynamics
- Chengdu Kanghong Biotech
- Chengdu Qiankun Veterinary Pharmaceuticals
- Chengdu S&km Biotechnology
- Chengdu Venus Health Pharmaceutical
- Chengdu Yongan Pharmaceutical
- Chiba Flour Milling
- Children's Hospital of Eastern Ontario (CHEO)
- China Agricultural University
- China Ocean Mineral Resource R&D Association
- Chinese PLA General Hospital
- Chiron Mimotopes
- ChoA Pharmaceutical
- Chongqing Health Forever Biotechnology
- Chongqing Tongnan Industrial Park
- Choong Ang Biotech
- ChoyBioLab
- Chr. Hansen
- ChromaDex
- Chronomics
- Chugai Pharmaceutical
- ChunLab
- Church and Dwight
- Cipla
- Clear Skin
- Cleveland BioLabs
- Cline Scientific
- Clinomics
- ClostraBio
- Cobalt Technologies
- Cobra
- COENBIO
- Cognoa
- Cold Genesys
- Colifast
- Conaris Research Institute
- Concentris Systems
- ConjuGon
- Conopco
- Consure Medical
- Corbicula
- Core Intellectual Properties Holdings
- Corn Products Development
- Coskata
- Cosmax
- Cosmo Foods
- CounterPoint Health Services
- Cowen
- Coyne IP Holdings
- CP Kelco
- Crestovo
- Crestovo Holdings
- Crowpierce
- Crystal Diagnostics
- CSG Electric Power Research Institute
- CTCBIO
- Cynity
- Cyntellect
- Cytogen
- CytoScan
- Cytovera
- Da Volterra
- Daewoong
- Daiichi Pure Chemicals
- Dalian Shengboda Technology
- Dana-Farber Cancer Institute
- DanjoungBio
- Dansico
- Danstar Ferment
- Dartmouth College
- Decoy Biosystems
- Department of Animal Husbandry & Dairying
- Department of Health Research
- Dermala
- Dermavri
- DermBiont
- DeWilde Iche
- Dh Technologies Development
- Diagnostic HYBRIDS
- Diamond V
- Dian Diagnostics
- DiaSys India
- DNA Genotek
- Dna Twopointo
- DnaNudge
- doc.ai
- Dong Wha Pharm
- Dow Global Technologies
- Dreambiz
- DSM Food & Beverage
- DSM IP Assets
- DuPont
- DynaGen
- E1 Biotech
- EarlyDiagnostics
- EatLittle
- EatSafe
- EderaGen
- Effector Cell Institute
- EIDIA
- Eisai
- Elan Pharma
- Elanco
- Eligo Bioscience
- Elwha
- Empire Technical Development
- Emulate
- Enbio
- Engeneic Molecular Delivery
- Enterobiome
- EnteroBiotix
- Enterome
- Entia Biosciences
- Entrinsic Biosciences
- Envisor
- Enzamin Lab
- Enzo Life Sciences
- Enzo Therapeutics
- Epigem
- EpiVax
- EPM Group
- Equility
- Era Masis
- Erber
- Erlus
- ESBATech, an Alcon Biomedical Research Unit
- Essen
- Essum
- Ethicon
- Euglena
- Eurogentec
- EUROIMMUN
- EUROIMMUN
- European Molecular Biology Laboratory
- Eveliqure Biotechnologies
- Evelo Biosciences
- Evive Biotech
- Evocatal
- Evolve BioSystems
- Evonik Degussa
- Evonik
- Evotec BioSystems
- Exocure Biosciences
- F. Hoffmann-La Roche
- Familial hypercholesterolemia Therapeutics
- Federalnoe Gosudarstvennoe Byudzhetnoe Obrazovatelnoe Uchrezhdenie Vysshego Obrazovaniya Astrakhansk
- Federation Bio
- Fertis
- Figene
- Finch
- First Wave BioPharma
- FIT-BioCeuticals Pty
- FitnessGenes
- FizzioFit Pty
- Flagship Pioneering
- Fluid-Screen
- FMT Medical, Nanjing
- Forte Biosciences
- Forte Group
- Foshan Baiguan Science And Technology
- Foshan City Shunde District Baotong Metal Technology
- Foshan Shunde Baotong Metal Technology
- Foshan Standard Biotech
- Freenome
- Fresenius Kabi
- Fritzmeier
- Frontier Science
- FSM Technologies
- FugenBio
- Fuji Chemical Industry
- Fujian Cosunter Pharmaceutical
- Fujian Shanhe Pharmaceutical
- Fujian Shengrun Biotechnology
- FUTURELIFE
- Fuzhou Dabeinong Biotech
- GAIA BioMedicine
- Galmed Pharmaceuticals
- Gambro
- Ganeden Biotech
- Gansu Agricultural University
- Ganzhou shanjian bio technolgy
- Gaozhou Twin Feed
- GE Healthcare
- GE Healthcare Life Sciences
- Gelesis
- Gene Bridges
- Genelux
- Genentech
- General Automation Lab Technologies
- General Mills
- Geneseeq Technology
- Genesis Research and Development Corporation
- Genetic Analysis
- Genetix Biotech
- GeneWeave Biosciences
- Genex Biomed
- GenMont Biotech
- Genome and Company
- Genome Pharmaceuticals Institute
- Genome Research
- Georgia State University Research
- GI Dynamics
- GigaBioMol Biotechnology
- Gilead Sciences
- Gilead
- Ginkgo Bioworks
- Ginreilab
- Giuliani Partners
- Glaxosmithkline Intellectual Property Development
- GlaxoSmithKline
- Global Cell Solutions
- Glovision
- Glycom
- Glycosyn
- GoDx
- GOM Health
- Goryo Chemical
- Gradientech
- Grape King
- Green Cross Veterinary Products
- Green Science Materials
- Guangdong Academy of Agricultural Sciences
- Guangdong Huankai
- Guangdong Languan Medical Biotechnology
- Guangdong Longsee Biomedical
- Guangdong Zhongke Tianyuan New Energy Technology
- Guangxi Academy of Agricultural Sciences
- Guangxi University
- Guangzhou Bio-gene Technology
- Guangzhou Huajin Pharmaceutical Technology
- Guangzhou HuiBoRui Biological Pharmaceutical Technology
- Guangzhou Liby Enterprise
- Guangzhou Pharmaceuticals
- Guangzhou Pharmaceuticals Corporation
- Guangzhou Xiangxue Pharmaceutical
- Guinness
- Guizhou Longyuan Cold Water Fishery
- Guizhou Salvage Pharmaceutical
- Gusto Global
- GUTSYBIO
- Habeebullah Life Sciences
- Hadjieva Dora Spartakova
- Haerimfucoidan
- Halliburton
- HANGZHOU TINKER BIOTECHNOLOGY
- Hanmi Pharmaceutical
- Hanwha Techwin(Formerly Samsung Techwin)
- Harbin Weike Biotechnology
- Harvard College
- Health Enhancement Products
- Hebei Senlang Biotechnology
- Hefei Haizhao Biotechnology
- Hefei PreceDo Pharmaceutical Technology
- Heinz Hosp
- Heitland & Petre International
- Helmholtz Centre for Infection Research
- Hem Pharma
- Henan Agricultural University
- Henan Delin Bio-products
- Henkel
- Henkel China Investment
- Her Majesty the Queen in Right of Canada
- Herbalife Nutrition India
- HerbKing Company
- Hervana Bio
- Hettich
- Heyuan twin Feed
- Hinoman
- Hirotsu Bio Science
- Hitachi
- Hitachi Chemical
- Hitachi Plant Services
- Holobiome
- Horizon Therapeutics
- Hosoda SHC
- Hospital Universitario Central de Asturias
- Houpu Biotechnology
- Hours
- HRL Laboratories
- Huazhong Agricultural University
- Hubble Biosciences
- Humabs BioMed
- Human Genome Sciences
- Human Longevity
- Hunan Agricultural University
- HUNAN KANGYIDA GRASS TECH
- Hunan Siqi Biopharmaceutical
- Hunter Immunology
- HyGIeaCare
- Hylabs
- HYPER lab
- Hyundai Motor
- IBM
- Ichilov Tech
- IDEX Health & Science
- IFB
- IFM Due
- IIT Kharagpur
- Ikeda Foods
- Ikena Oncology
- IlDong Pharmaceutical
- Illumina
- Ilya Pharma
- IMETH
- Immodulon Therapeutics
- Immortal Technologies
- Immune Therapeutics
- ImmuneBiotech Medical Sweden AB
- ImmuniMed
- Immunology Laboratory
- ImmuRx
- IMP Innovative Medical Products
- Imperial Innovations
- Indevex AB (publ)
- Indian Oil Corporation Ltd
- Indicator Systems
- Infinity Pharmaceuticals
- Innate cell therapy
- Inner Mongolia University
- Innovotech
- INRA
- Institut national de la recherche agronomique
- Institute of Agricultural Economics and Technology, Hubei Academy of Agricultural Sciences, Wuhan
- Institute of Animal Science of CAAS
- Instituto Superior de Agronomia
- Integrated Nano-Technologies
- Intercell Pharma
- Intercept Pharmaceuticals
- Intercontinental Great Brands
- International Dehydrated Foods
- InterSTEM
- Intrinsic Medicine
- iNtRON Biotechnology
- Iowa State University research
- Ipsen Biopharmaceuticals
- iRiccorgPharm Pty
- Ironwood Pharmaceuticals
- IS-diagnostics
- iSense
- Isis Pharmaceuticals
- Island Water Technologies
- Isotechnika
- ISOThrive
- Iterative Scopes
- J-Oil Mills
- J2KBIO
- Jaguar Health
- Janssen Biotech
- Japan Agency for Marine-Earth Science and Technology
- Japan Aviation Electronics Industry
- Japan Eco-science
- Japan Science and Technology
- Japan Tobacco
- Jarrow Formulas
- JAYEON ENGINEERING
- JCBIO
- Jenpolymer Materials
- Jiangmen Kailin Trade
- Jiangsu Academy of Agricultural Sciences
- Jiangsu Shiyutian Biotechnology
- Jiaxing Yutong Technology
- Jilin University
- Jilin Zixin Pharmaceutical
- Jilin Zixin Pharmaceutical Research Institution
- Jinan Pantheon Bio-Technology
- Jinseki International School
- Johnson & Johnson Consumer
- Johnson & Johnson MedTech
- Johnson & Johnson Vision
- Joslin Diabetes Center
- JP Cullen
- Jung Lab
- Junwei Chen, University of Illinois at Urbana-Champaign
- Kagami
- KAIROS Scientific
- Kaleido Biosciences
- KAMEDA SEIKA
- KAntrak
- Karydo TherapeutiX
- Kate Farms
- Kawano Lab
- Kawashima
- Keiyo Plant Engineering
- Kemin
- Kemira
- Kennan Eisei Kogyo
- Kennel Club of India
- KI Chemical Industry
- Kibow Biotech
- King Brewery
- KingMed Diagnostics
- KNR
- Kobiolabs
- Kode Biotech
- Komipharm International
- Konica Minolta
- Korbi
- Korea Yakult
- Kortherm Science
- KPN innovations
- Kureha's chemical industry
- Kwang Dong Pharmaceutical
- Kyodo Milk Industry
- KYTHERA Biopharmaceuticals
- L G Pharmaceuticals
- La for lab
- LabGenomics
- LABIO
- Lac2Biome
- Lacerta Technology
- Lactobio
- Laoken Medical Technology
- Laves-Arzneimittel
- Lawrence Livermore National Security
- LCS Biotech
- Lepetit
- LG Chem
- LG Household & Health Care
- LG Innotek
- Liaoning Gerui Shite Biological Pharmace utical
- Liaoning Nakejia Biopharmaceutical
- Liaoning Pharmaceutical
- Life Sciences Nutrition
- LifeBridge Health
- LiFeng-Tech
- LifeScan
- LifeTaq
- Lightspeed India Partners
- Linde
- Linnane Pharma
- LISCure Biosciences
- LNC Therapeutics
- Locus Agricultural Solutions
- Locus FS
- Lonza
- Los Alamos National Security
- LOTTE Confectionery
- Lotte
- Lululemon athletica
- LunaPBC
- Lysando
- Lytone Enterprise
- M D SCIENCE COLLEGE
- MaaT Pharma
- Macrogen
- MAIN
- MakeSense Digital Health
- Manatee ELC
- MapPath
- Marina Biotech
- Marrone Bio Innovations
- Mars
- Maruzen Pharmaceuticals
- Mary Kay
- MatriSys Bioscience
- Maxygen
- Maya Industries
- MC Pharma
- MCM Klosterfrau
- Md Abdul Kafi
- MD Healthcare
- Mds
- Mead Johnson Nutrition
- Medi Service
- Medical & Biological Laboratories
- Medical College of Wisconsin
- Medicomp Systems
- MedImmune
- Medytox
- Megmilk Snow Brand
- Meiji
- Meiji Feed
- Meisho
- Memorial Sloan Kettering Cancer Center
- Mendes S R L Unipersonale Mend
- Merck
- Merck Sharp & Dohme
- Merck
- Merial
- Merz Aesthetics
- Metabologenomics
- Metabolon
- Metagenics
- Metogen
- miacom diagnostics
- Mican Technologies
- Micro-nature
- Microba Life Sciences
- MicrobeDx
- Microbes
- Microbial Discovery Group
- Microbial Screening Technologies Pty
- Microbiome Health Research Institute
- Microbiome Labs
- Microbiome Therapeutics
- Microbiome-directed therapeutics
- MicroBioSensor
- Microbiota I-Center
- Microbiotica
- Microcide Pharmaceuticals
- MICRODIGITAL
- MicroMass
- MicroPort
- MicrosensDx
- Midori USA
- Millennium Pharmaceuticals
- Miltenyi Biotec
- Ministry of Agriculture and Rural Development of the State of Israel
- Mirvie
- Mitsui Chemicals
- MiZ
- MODNBIO
- Molecular Devices
- Molecular Probes
- Molecular Rx
- Momenta Pharmaceuticals
- Monogram Biosciences
- Monsanto
- Moon (Beijing) Biotech
- Moon (Beijing) Biotech
- Moore Enterprises
- Morinaga Milk
- Moringo Organics
- MR Innovation
- Mugen uri
- Multi Magnectics Incorporated
- MultiGene Vascular Systems
- Multigerm (UK) Enterprise
- MultiplAI Health
- Multistars Biotechnology
- Muromachi Chemicals
- MuWells
- MyBiotics
- Mycotox Solutions
- Myoridge
- Myriad Genetics
- Myriad Technologies
- N.M.B. Medical Applications
- Nai
- Nakano Vinegar
- Naked Biome
- Nambo
- Nanchang Lijian Pharmaceutical
- Nanjing Agricultural University
- Nanjing Drum Tower Hospital
- Nanjing Legend Biotech
- Nanjing Medical University
- Nanjing Mingshan New Material Technology
- Nanjing Sen Nan Biotechnology Research
- Nanjing Sinogen Biotech & Pharmaceutical
- Nanjing University of Aeronautics and Astronautics
- Nano3D Biosciences
- NANOBIOSYS
- NanoScent
- NanoTYPE
- National Agriculture and Food Research Organization
- National Institute of Agricultural Research
- National Research Institute for Sustainable Development
- National Technology & Engineering Solutions of Sandia, LLC has 12,000 total employees across all of its locations and generat
- Native Microbials
- Nature Biotechnology
- Naturwohl Pharma
- NEIKER-Instituto Vasco de Investigación y Desarrollo Agrario
- Netanya-Plasmatec
- New Horizon Health
- Newgen
- NewLife Bioscience
- Nexcelom
- Next Biosciences
- NextGem
- NGM Biopharmaceuticals
- NH Foods
- Nihon Kohden
- Nippon Shinyaku
- Nissan Chemical
- Nisshin Pharma
- Nissin Food
- Nissui Pharmaceutical
- Nitto Pharmaceutical Industries
- Noble Institute Of Medical Technology
- NOFORM
- Nomir Medical Technologies
- Nona International
- Nongfeng Biotechnology
- Nongshim
- Northeast Agricultural University
- Noster
- Novartis
- Novo Nordisk
- Novome Biotechnologies
- Novozymes
- Novus International
- NRI R&D Patent Licensing
- NuBiome
- NuBiyota
- numares
- Nuohoi Pharmaceutical Technology
- Nutraceutix
- Nutrition & Biosciences
- Nutrition Physiology Company
- Oberon Sciences
- Ocean Engineering
- Oncogene
- Oncohost
- Oncorena
- Oncotherapy science
- Ondek Pty
- OpenDNA
- Operating Room Innovations
- Optibiotix
- Oragenics
- Oral health
- Orbis Health Solutions
- OrganoBalance
- Organobalance
- Ori Biotech
- Oriental Yeast
- Original equipment manufacturer (OEM)
- Ortho Clinical Diagnostics
- Orthogen
- Orvinum
- Osel
- OSI Pharmaceuticals
- OTOLINK
- Otsuka Pharmaceutical
- Otsuka Pharmaceutical Factory
- Oxford University Innovation
- Oxoid
- OxThera
- Oxthera Intellectual Property
- Oxyrase
- Panasonic IP Management
- Pathogenetix
- Paul de la Pena
- PCI Biotech
- Peachstate Health Management
- Peak-Bio
- Pebble Labs
- Pendulum Therapeutics
- Percivia
- Perfect (China)
- Perfect (China)
- Performance Labs
- Persephone
- Persephone Biosciences
- Perthera
- Pesquisa Agropecuária
- Peter MacCallum Cancer Centre
- Pfizer
- Pharma-Zentrale
- PharmaBiome
- PharmaLegacy Laboratories (Shanghai)
- Pharmbio Korea
- Phase Holographic Imaging
- Phenex Pharmaceuticals
- Phico Therapeutics
- PhotoPill Medical
- Phylagen
- Piramal Enterprises Limited
- Pivot Bio
- PL Bio
- Plant Bioscience
- PlantArcBio
- Pleonova
- Plexus Worldwide
- PneumRx
- Pola Chemical Industries
- Poultry Institute, Shandong Academy of Agricultural Sciences
- Precision medicine in inflammatory bowel disease
- Premex
- Premune
- Presidio Pharmaceuticals
- Prime Discoveries
- Pro Pharmaceuticals
- Probi
- Probionase Therapies
- Probiotech
- Probiotical
- Procter & Gamble
- Professional Compounding Centers of America
- Profit Success
- Progenity
- Progressive BioActives
- Prokarium
- Prolacta Bioscience
- ProPrev
- Prostemics
- Protectimmun
- Proteologics
- Psomagen
- Pulmuone
- PureFlora
- Q Bio
- QBI
- QIAGEN CLC Genomics
- QIAGEN
- Qingdao Agricultural University
- Qingdao Qingquan Biotechnology
- Quadrant Biosciences
- Qualis LAB
- QuantaMatrix
- QUANTEC
- Quorum Innovations
- Rambam MedTech
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