Biomechanics of the Female Reproductive System: Breast and Pelvic Organs: From Models to Patients synthesizes complementary advances in women's reproductive biomechanics, medical imaging analysis, patient-specific characterization, and computational finite element models. The book discusses the biomechanical aspects related to the breast and female pelvic floor system at each step of development. The table of contents also covers certain events and diseases, including cancers, delivery, aging, breast, hysterectomy or prolapse surgery. It presents the main biomechanical experimental results obtained and models developed this last decade to highlight the importance of accounting for patient-specific history and aging characteristics to consider damage growth effect and impact.
As part of Elsevier's Biomechanics of Living Organs series, this book provides an opportunity for students, researchers, clinicians and engineers to study the main topics related to the biomechanics of the women's reproductive system in a single book written by a global base of experts.
Table of Contents
PART 1 Backgrounds: anatomy, physiology, and physio-pathology
1. Pelvic floor functional anatomy
2. Epidemiology and pathophysiology of pelvic organ prolapse and urinary incontinence in women
3. Current surgical treatments for women's genital prolapse
4. Physiology and physiopathology of pregnancy and delivery
PART 2 Mechanical properties
constitutive laws
experimental characterizations
5. Inverse problems in the characterization of soft connective tissue: perspective for reproduction system
6. Mechanical properties of women pelvic soft tissues
7. Mechanical properties of breast tissue
8. Evolution of mechanical properties with pathology & aging: application to pelvic tissues?
9. Mechanical properties of pelvic implants: interaction between implants and tissue
10. Constitutive models of soft connective tissues under large strain: application to pelvic tissue?
PART 3 Clinical imaging, investigations tools, and characterization
11. Medical imaging and patient-specific modeling of women pelvic system: application to magnetic resonance images
12. Quantitative assessment of pelvic mobility in women using MRI image analysis
13. Patient-specific biomechanical modeling for applications in breast cancer diagnosis and treatment
14. Ultrasound elastography: in vivo assessment of tissue stiffness
PART 4 From biomechanical models to medical devices, and patients treatments
15. Numerical simulation of vaginal delivery
16. Numerical models for breast surgery and reconstruction
17. A numerical model for prolapse surgery
18. Augmented reality biomechanical simulations for pelvic conditions diagnoses
19. Towards patient-specific treatment in gynecologic surgery: recent development and perspectives
Authors
Mathias Brieu PhD, Professor of mechanical engineering at California State University in Los Angeles, United States; Professor of mechanics at Centrale Lille, France.. He is a Professor of Mechanical Engineering with a specialty in mechanics of materials and computational mechanics. Prior to joining Cal State LA, he was a Professor in a higher education school of engineering: Centrale Lille. He still interacts with his former institution and his research is developed in a synergy between France and the USA; his specialty now is Biomedical Engineering.His research activities are based on the triptych of mechanics of materials: experimental characterization constitutive modelling, and numerical and computational methods.
He is focused on soft polymers and bio-polymers. His activities can be summarized in 3 fields:
.Behavior, and damage of synthetic polymers
.Behavior of human soft tissue and medical implants,
.Development and design of Medical Devices for patient-specific surgery. Michel Cosson Professor of Gynecology and Obstetrics, Lille University, France; President, Group for Pelviperineology of the French Medical Society of Gynecology and Obstetrics. Pr. Michel Cosson is the Medical director of the UNF3S French numerical university. He is involved in 3D anatomy and pedagogical research. He is also the Head of the Gynecological unit of the University Hospital in Lille, France and Professor of Gynecology Obstetrics at the Medical University. He is the author and co-author of several publications. Pr. Cosson's areas of interest include biomechanical properties of pelvic tissues & 3D biomechanical simulation of the female pelvic cavity. Poul Nielsen Professor of Biomechanics and Computational Mechanics, Chair of the Physiome Incorporated Executive Committee and Member, VPH Institute Board of Directors, Auckland Bioengineering Institute, University of Auckland, New Zealand. Poul's research focuses on using novel instrumentation, detailed computational models, and quantitative descriptions of physical processes to gain a better understanding of human physiology. Many of his projects couple mathematical modelling with innovative instrumentation to improve our ability to understand and interpret measurements of complex biological systems, subject to the constraints of well-understood physical conservation and balance laws.
