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Anaplastic Lymphoma Kinase Inhibitors Market Size, Market Share, Application Analysis, Regional Outlook, Growth Trends, Key Players, Competitive Strategies and Forecasts, 2022 to 2030

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    Report

  • 115 Pages
  • August 2022
  • Region: Global
  • Acute Market Reports
  • ID: 5707254

Industry Outlook

The anaplastic lymphoma kinase (ALK) inhibitors market is set to reach from US$ 2,130.8 Mn in 2020 to 16,889.4 Mn by 2030 keen to demonstrate exuberating growth at a compounded annual growth rate (CAGR) of 21.2% during the forecast period from 2022 to 2030. Lung cancer is the second most occurring type of cancer in both men and women population worldwide. Increased consumption of tobacco, unhealthy lifestyle and stress are the major risk factor responsible for the occurrence of lung cancer. A strong drug pipeline of second and third-generation ALK inhibitors being currently studied in various stages of clinical trials are being developed specifically for the treatment of non small cell lung cancer (NSCLC).

Excellent pharmacodynamic and pharmacokinetic properties drive the market growth of first generation ALK inhibitors

Non small cell lung cancer (NSCLC) is the most common type of lung cancer occurring throughout the globe. The prognosis of the NSCLC is difficult and its initial screening is rather poor which significantly increases the requirement for development of targeted drug therapy for its treatment. FDA has approved only 2 drugs specifically for the treatment of NSCLC In the present scenario first generation ALK inhibitor Crizotinib is spearheading the molecule segment for anaplastic lymphoma kinase inhibitors market. It is basically an aminopyridine and piperidine derivative which selectively inhibits receptor tyrosine kinase and the ALK fusion proteins during the treatment of NSCLC. It has the potency to inhibit tumor cell growth. Alectinib hydrochloride is another first line ALK inhibitor which effectively inhibits wild type ALK point mutant variants and disrupts the tumor cell growth associated with advanced stage NSCLC. Hence, excellent pharmacodynamic and pharmacokinetic properties together drive the market growth for first generation ALK inhibitors.

Rising prevalence of lung cancer and affordable reimbursement scenario together drive the market growth in North America region

Representing a share of 36.2% North America is currently leading the regional segment for anaplastic lymphoma kinase (ALK) inhibitors market. According to the research findings of American Society of Clinical Oncology (ASCO), in 2021, approximately 228,150 U.S. citizens have been reported to be suffering with lung cancer with a high prevalence rate in African American people. Affordable reimbursement scenario pertaining to the treatment of non small cell lung cancer drives the market growth ALK inhibitors in North America region. Europe is in the second place with 29.8% market share primarily due to huge prevalence rate of lung cancer in the European Union which is 54 per 100,000 people as brought forward by the 2020 statistical report of European Commission. Supportive regulatory environment provided by the European Medical Agency to expedite the clinical trials pertaining to second and third generation anaplastic lymphoma kinase inhibitors for the treatment of non small cell lung cancer (NSCLC). Asia Pacific presently accounts for 15.5% market share and is keen to register outstanding growth during the forecast period on account of significant rise in tobacco consumption, thereby promoting the proliferation of NSCLC and developing healthcare infrastructure.

Biopharmaceutical companies actively seeking to create a strong foothold in the anaplastic lymphoma kinase inhibitors market are Betta Pharmaceutcials Co., Ltd., Crtierium, Inc., F.Hoffman-La Roche Ltd., Helsinn Therapeutics, Novartis AG., Oncoethix GmbH, Pfizer, Inc., Takeda Pharmaceutical Co., Ltd., Xcovery Holding Company, LLC and Tesaro, Inc.

Historical & Forecast Period

This study report represents analysis of each segment from 2020 to 2030 considering 2021 as the base year. Compounded Annual Growth Rate (CAGR) for each of the respective segments estimated for the forecast period of 2022 to 2030.

The current report comprises of quantitative market estimations for each micro market for every geographical region and qualitative market analysis such as micro and macro environment analysis, market trends, competitive intelligence, segment analysis, porters five force model, top winning strategies, top investment markets, emerging trends and technological analysis, case studies, strategic conclusions and recommendations and other key market insights.

Research Methodology

The complete research study was conducted in three phases, namely: secondary research, primary research, and expert panel review. key data point that enables the estimation of Anaplastic Lymphoma Kinase Inhibitors market are as follows:
  • Research and development budgets of manufacturers and government spending
  • Revenues of key companies in the market segment
  • Number of end users and consumption volume, price and value.
  • Geographical revenues generate by countries considered in the report
  • Micro and macro environment factors that are currently influencing the Anaplastic Lymphoma Kinase Inhibitors market and their expected impact during the forecast period.
Market forecast was performed through proprietary software that analyzes various qualitative and quantitative factors. Growth rate and CAGR were estimated through intensive secondary and primary research. Data triangulation across various data points provides accuracy across various analyzed market segments in the report. Application of both top down and bottom-up approach for validation of market estimation assures logical, methodical and mathematical consistency of the quantitative data.

Market Segmentation

Molecule

  • Crizotinib
  • Ceritinib
  • Alectinib Hydrochloride

Key questions answered in this report

  • What are the key micro and macro environmental factors that are impacting the growth of Anaplastic Lymphoma Kinase Inhibitors market?
  • What are the key investment pockets with respect to product segments and geographies currently and during the forecast period?
  • Estimated forecast and market projections up to 2030.
  • Which segment accounts for the fastest CAGR during the forecast period?
  • Which market segment holds a larger market share and why?
  • Are low and middle-income economies investing in the Anaplastic Lymphoma Kinase Inhibitors market?
  • Which is the largest regional market for Anaplastic Lymphoma Kinase Inhibitors market?
  • What are the market trends and dynamics in emerging markets such as Asia Pacific, Latin America, and Middle East & Africa?
  • Which are the key trends driving Anaplastic Lymphoma Kinase Inhibitors market growth?
  • Who are the key competitors and what are their key strategies to enhance their market presence in the Anaplastic Lymphoma Kinase Inhibitors market worldwide?


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Table of Contents

1. Preface
1.1. Report Description
1.1.1. Purpose of the Report
1.1.2. Target Audience
1.1.3. Key Offerings
1.2. Market Segmentation
1.3. Research Methodology
1.3.1. Phase I - Secondary Research
1.3.2. Phase II - Primary Research
1.3.3. Phase III - Expert Panel Review
1.3.4. Assumptions
1.3.5. Approach Adopted
2. Executive Summary
2.1. Market Snapshot: Global Anaplastic Lymphoma Kinase Inhibitors Market
2.2. Global Anaplastic Lymphoma Kinase Inhibitors Market, By Molecule, 2021 (US$ Million)
2.3. Global Anaplastic Lymphoma Kinase Inhibitors Market, By Geography, 2021 (US$ Million)
2.4. Attractive Investment Proposition by Geography, 2021
3. Anaplastic Lymphoma Kinase Inhibitors Market: Competitive Analysis
3.1. Market Positioning of Key Anaplastic Lymphoma Kinase Inhibitors Market Vendors
3.2. Strategies Adopted by Anaplastic Lymphoma Kinase Inhibitors Market Vendors
3.3. Key Industry Strategies
3.4. Tier Analysis 2021 Versus 2030
4. Anaplastic Lymphoma Kinase Inhibitors Market: Macro Analysis & Market Dynamics
4.1. Introduction
4.2. Global Anaplastic Lymphoma Kinase Inhibitors Market Value, 2020 - 2030, (US$ Million)
4.3. Market Dynamics
4.3.1. Market Drivers
4.3.2. Market Restraints
4.3.3. Key Challenges
4.3.4. Key Opportunities
4.4. Impact Analysis of Drivers and Restraints
4.5. See-Saw Analysis
5. Anaplastic Lymphoma Kinase Inhibitors Market: By Molecule, 2020-2030, USD (Million)
5.1. Market Overview
5.2. Growth & Revenue Analysis: 2021 Versus 2030
5.3. Market Segmentation
5.3.1. Crizotinib
5.3.2. Ceritinib
5.3.3. Alectinib Hydrochloride
6. North America Anaplastic Lymphoma Kinase Inhibitors Market, 2020-2030, USD (Million)
6.1. Market Overview
6.2. Anaplastic Lymphoma Kinase Inhibitors Market: By Molecule, 2020-2030, USD (Million)
6.3.Anaplastic Lymphoma Kinase Inhibitors Market: By Region, 2020-2030, USD (Million)
6.3.1.North America
6.3.1.1. U.S.
6.3.1.1.1. Anaplastic Lymphoma Kinase Inhibitors Market: By Molecule, 2020-2030, USD (Million)
6.3.1.2. Canada
6.3.1.2.1. Anaplastic Lymphoma Kinase Inhibitors Market: By Molecule, 2020-2030, USD (Million)
6.3.1.3. Rest of North America
6.3.1.3.1. Anaplastic Lymphoma Kinase Inhibitors Market: By Molecule, 2020-2030, USD (Million)
7. UK and European Union Anaplastic Lymphoma Kinase Inhibitors Market, 2020-2030, USD (Million)
7.1. Market Overview
7.2. Anaplastic Lymphoma Kinase Inhibitors Market: By Molecule, 2020-2030, USD (Million)
7.3.Anaplastic Lymphoma Kinase Inhibitors Market: By Region, 2020-2030, USD (Million)
7.3.1.UK and European Union
7.3.1.1. UK
7.3.1.1.1. Anaplastic Lymphoma Kinase Inhibitors Market: By Molecule, 2020-2030, USD (Million)
7.3.1.2. Germany
7.3.1.2.1. Anaplastic Lymphoma Kinase Inhibitors Market: By Molecule, 2020-2030, USD (Million)
7.3.1.3. Spain
7.3.1.3.1. Anaplastic Lymphoma Kinase Inhibitors Market: By Molecule, 2020-2030, USD (Million)
7.3.1.4. Italy
7.3.1.4.1. Anaplastic Lymphoma Kinase Inhibitors Market: By Molecule, 2020-2030, USD (Million)
7.3.1.5. France
7.3.1.5.1. Anaplastic Lymphoma Kinase Inhibitors Market: By Molecule, 2020-2030, USD (Million)
7.3.1.6. Rest of Europe
7.3.1.6.1. Anaplastic Lymphoma Kinase Inhibitors Market: By Molecule, 2020-2030, USD (Million)
8. Asia Pacific Anaplastic Lymphoma Kinase Inhibitors Market, 2020-2030, USD (Million)
8.1. Market Overview
8.2. Anaplastic Lymphoma Kinase Inhibitors Market: By Molecule, 2020-2030, USD (Million)
8.3.Anaplastic Lymphoma Kinase Inhibitors Market: By Region, 2020-2030, USD (Million)
8.3.1.Asia Pacific
8.3.1.1. China
8.3.1.1.1. Anaplastic Lymphoma Kinase Inhibitors Market: By Molecule, 2020-2030, USD (Million)
8.3.1.2. Japan
8.3.1.2.1. Anaplastic Lymphoma Kinase Inhibitors Market: By Molecule, 2020-2030, USD (Million)
8.3.1.3. India
8.3.1.3.1. Anaplastic Lymphoma Kinase Inhibitors Market: By Molecule, 2020-2030, USD (Million)
8.3.1.4. Australia
8.3.1.4.1. Anaplastic Lymphoma Kinase Inhibitors Market: By Molecule, 2020-2030, USD (Million)
8.3.1.5. South Korea
8.3.1.5.1. Anaplastic Lymphoma Kinase Inhibitors Market: By Molecule, 2020-2030, USD (Million)
8.3.1.6. Rest of Asia Pacific
8.3.1.6.1. Anaplastic Lymphoma Kinase Inhibitors Market: By Molecule, 2020-2030, USD (Million)
9. Latin America Anaplastic Lymphoma Kinase Inhibitors Market, 2020-2030, USD (Million)
9.1. Market Overview
9.2. Anaplastic Lymphoma Kinase Inhibitors Market: By Molecule, 2020-2030, USD (Million)
9.3.Anaplastic Lymphoma Kinase Inhibitors Market: By Region, 2020-2030, USD (Million)
9.3.1.Latin America
9.3.1.1. Brazil
9.3.1.1.1. Anaplastic Lymphoma Kinase Inhibitors Market: By Molecule, 2020-2030, USD (Million)
9.3.1.2. Mexico
9.3.1.2.1. Anaplastic Lymphoma Kinase Inhibitors Market: By Molecule, 2020-2030, USD (Million)
9.3.1.3. Rest of Latin America
9.3.1.3.1. Anaplastic Lymphoma Kinase Inhibitors Market: By Molecule, 2020-2030, USD (Million)
10. Middle East and Africa Anaplastic Lymphoma Kinase Inhibitors Market, 2020-2030, USD (Million)
10.1. Market Overview
10.2. Anaplastic Lymphoma Kinase Inhibitors Market: By Molecule, 2020-2030, USD (Million)
10.3.Anaplastic Lymphoma Kinase Inhibitors Market: By Region, 2020-2030, USD (Million)
10.3.1.Middle East and Africa
10.3.1.1. GCC
10.3.1.1.1. Anaplastic Lymphoma Kinase Inhibitors Market: By Molecule, 2020-2030, USD (Million)
10.3.1.2. Africa
10.3.1.2.1. Anaplastic Lymphoma Kinase Inhibitors Market: By Molecule, 2020-2030, USD (Million)
10.3.1.3. Rest of Middle East and Africa
10.3.1.3.1. Anaplastic Lymphoma Kinase Inhibitors Market: By Molecule, 2020-2030, USD (Million)
11. Company Profile
11.1. Betta Pharmaceuticals Co., Ltd.
11.1.1. Company Overview
11.1.2. Financial Performance
11.1.3. Product Portfolio
11.1.4. Strategic Initiatives
11.2. Criterium, Inc.
11.2.1. Company Overview
11.2.2. Financial Performance
11.2.3. Product Portfolio
11.2.4. Strategic Initiatives
11.3. F. Hoffman-La Roche Ltd.
11.3.1. Company Overview
11.3.2. Financial Performance
11.3.3. Product Portfolio
11.3.4. Strategic Initiatives
11.4. Helsinn Therapeutics
11.4.1. Company Overview
11.4.2. Financial Performance
11.4.3. Product Portfolio
11.4.4. Strategic Initiatives
11.5. Novartis AG
11.5.1. Company Overview
11.5.2. Financial Performance
11.5.3. Product Portfolio
11.5.4. Strategic Initiatives
11.6. Oncoethix GmbH
11.6.1. Company Overview
11.6.2. Financial Performance
11.6.3. Product Portfolio
11.6.4. Strategic Initiatives
11.7. Pfizer, Inc.
11.7.1. Company Overview
11.7.2. Financial Performance
11.7.3. Product Portfolio
11.7.4. Strategic Initiatives
11.8. Takeda Pharmaceutical Co., Ltd.
11.8.1. Company Overview
11.8.2. Financial Performance
11.8.3. Product Portfolio
11.8.4. Strategic Initiatives
11.9. Xcovery Holding Company, LLC
11.9.1. Company Overview
11.9.2. Financial Performance
11.9.3. Product Portfolio
11.9.4. Strategic Initiatives
11.10. Tesaro, Inc.
11.10.1. Company Overview
11.10.2. Financial Performance
11.10.3. Product Portfolio
11.10.4. Strategic Initiatives
List of Figures
Figure 1 Global Anaplastic Lymphoma Kinase Inhibitors Market: Market Coverage
Figure 2 Research Methodology and Data Sources
Figure 3 Market Size Estimation - Top Down & Bottom-Up Approach
Figure 4 Global Anaplastic Lymphoma Kinase Inhibitors Market: Quality Assurance
Figure 5 Global Anaplastic Lymphoma Kinase Inhibitors Market, By Molecule, 2021
Figure 6 Global Anaplastic Lymphoma Kinase Inhibitors Market, By Geography, 2021
Figure 7 Market Geographical Opportunity Matrix - Global Anaplastic Lymphoma Kinase Inhibitors Market, 2021
Figure 8 Market Positioning of Key Anaplastic Lymphoma Kinase Inhibitors Market Players, 2021
Figure 9 Global Anaplastic Lymphoma Kinase Inhibitors Market - Tier Analysis - Percentage of Revenues by Tier Level, 2021 Versus 2030
Figure 10 Global Anaplastic Lymphoma Kinase Inhibitors Market, By Molecule, 2021 Vs 2030, %
Figure 11 U.S. Anaplastic Lymphoma Kinase Inhibitors Market (US$ Million), 2020 - 2030
Figure 12 Canada Anaplastic Lymphoma Kinase Inhibitors Market (US$ Million), 2020 - 2030
Figure 13 Rest of North America Anaplastic Lymphoma Kinase Inhibitors Market (US$ Million), 2020 - 2030
Figure 14 UK Anaplastic Lymphoma Kinase Inhibitors Market (US$ Million), 2020 - 2030
Figure 15 Germany Anaplastic Lymphoma Kinase Inhibitors Market (US$ Million), 2020 - 2030
Figure 16 Spain Anaplastic Lymphoma Kinase Inhibitors Market (US$ Million), 2020 - 2030
Figure 17 Italy Anaplastic Lymphoma Kinase Inhibitors Market (US$ Million), 2020 - 2030
Figure 18 France Anaplastic Lymphoma Kinase Inhibitors Market (US$ Million), 2020 - 2030
Figure 19 Rest of Europe Anaplastic Lymphoma Kinase Inhibitors Market (US$ Million), 2020 - 2030
Figure 20 China Anaplastic Lymphoma Kinase Inhibitors Market (US$ Million), 2020 - 2030
Figure 21 Japan Anaplastic Lymphoma Kinase Inhibitors Market (US$ Million), 2020 - 2030
Figure 22 India Anaplastic Lymphoma Kinase Inhibitors Market (US$ Million), 2020 - 2030
Figure 23 Australia Anaplastic Lymphoma Kinase Inhibitors Market (US$ Million), 2020 - 2030
Figure 24 South Korea Anaplastic Lymphoma Kinase Inhibitors Market (US$ Million), 2020 - 2030
Figure 25 Rest of Asia Anaplastic Lymphoma Kinase Inhibitors Market (US$ Million), 2020 - 2030
Figure 26 Brazil Anaplastic Lymphoma Kinase Inhibitors Market (US$ Million), 2020 - 2030
Figure 27 Mexico Anaplastic Lymphoma Kinase Inhibitors Market (US$ Million), 2020 - 2030
Figure 28 Rest of Latin America Anaplastic Lymphoma Kinase Inhibitors Market (US$ Million), 2020 - 2030
Figure 29 GCC Anaplastic Lymphoma Kinase Inhibitors Market (US$ Million), 2020 - 2030
Figure 30 Africa Anaplastic Lymphoma Kinase Inhibitors Market (US$ Million), 2020 - 2030
Figure 31 Rest of Middle East and Africa Anaplastic Lymphoma Kinase Inhibitors Market (US$ Million), 2020 - 2030
List of Tables
Table 1 Global Anaplastic Lymphoma Kinase Inhibitors Market By Molecule, 2020-2030, USD (Million)
Table 2 North America Anaplastic Lymphoma Kinase Inhibitors Market By Molecule, 2020-2030, USD (Million)
Table 3 U.S. Anaplastic Lymphoma Kinase Inhibitors Market By Molecule, 2020-2030, USD (Million)
Table 4 Canada Anaplastic Lymphoma Kinase Inhibitors Market By Molecule, 2020-2030, USD (Million)
Table 5 Rest of North America Anaplastic Lymphoma Kinase Inhibitors Market By Molecule, 2020-2030, USD (Million)
Table 6 UK and European Union Anaplastic Lymphoma Kinase Inhibitors Market By Molecule, 2020-2030, USD (Million)
Table 7 UK Anaplastic Lymphoma Kinase Inhibitors Market By Molecule, 2020-2030, USD (Million)
Table 8 Germany Anaplastic Lymphoma Kinase Inhibitors Market By Molecule, 2020-2030, USD (Million)
Table 9 Spain Anaplastic Lymphoma Kinase Inhibitors Market By Molecule, 2020-2030, USD (Million)
Table 10 Italy Anaplastic Lymphoma Kinase Inhibitors Market By Molecule, 2020-2030, USD (Million)
Table 11 France Anaplastic Lymphoma Kinase Inhibitors Market By Molecule, 2020-2030, USD (Million)
Table 12 Rest of Europe Anaplastic Lymphoma Kinase Inhibitors Market By Molecule, 2020-2030, USD (Million)
Table 13 Asia Anaplastic Lymphoma Kinase Inhibitors Market By Molecule, 2020-2030, USD (Million)
Table 14 China Anaplastic Lymphoma Kinase Inhibitors Market By Molecule, 2020-2030, USD (Million)
Table 15 Japan Anaplastic Lymphoma Kinase Inhibitors Market By Molecule, 2020-2030, USD (Million)
Table 16 India Anaplastic Lymphoma Kinase Inhibitors Market By Molecule, 2020-2030, USD (Million)
Table 17 Australia Anaplastic Lymphoma Kinase Inhibitors Market By Molecule, 2020-2030, USD (Million)
Table 18 South Korea Anaplastic Lymphoma Kinase Inhibitors Market By Molecule, 2020-2030, USD (Million)
Table 19 Latin America Anaplastic Lymphoma Kinase Inhibitors Market By Molecule, 2020-2030, USD (Million)
Table 20 Brazil Anaplastic Lymphoma Kinase Inhibitors Market By Molecule, 2020-2030, USD (Million)
Table 21 Mexico Anaplastic Lymphoma Kinase Inhibitors Market By Molecule, 2020-2030, USD (Million)
Table 22 Rest of Latin America Anaplastic Lymphoma Kinase Inhibitors Market By Molecule, 2020-2030, USD (Million)
Table 23 Middle East and Africa Anaplastic Lymphoma Kinase Inhibitors Market By Molecule, 2020-2030, USD (Million)
Table 24 GCC Anaplastic Lymphoma Kinase Inhibitors Market By Molecule, 2020-2030, USD (Million)
Table 25 Africa Anaplastic Lymphoma Kinase Inhibitors Market By Molecule, 2020-2030, USD (Million)
Table 26 Rest of Middle East and Africa Anaplastic Lymphoma Kinase Inhibitors Market By Molecule, 2020-2030, USD (Million)

Companies Mentioned

  • Betta Pharmaceutcials Co. Ltd.
  • Crtierium Inc.
  • F.Hoffman-La Roche Ltd.
  • Helsinn Therapeutics
  • Novartis AG.
  • Oncoethix GmbH
  • Pfizer Inc.
  • Takeda Pharmaceutical Co. Ltd.
  • Xcovery Holding Company
  • LLC and Tesaro Inc.