Bioactive Lipid Mediators in Cardiopulmonary Pharmacology, Volume 97 updates readers on topics surrounding Bioactive lipid mediators. These mediators are involved in a vast array of signaling pathways that regulate both physiological and pathophysiological responses. Chapters in this new release include Cyclooxygenases and Vascular Function, Cyclooxygenases and Platelet Function, Eicosanoids and Cardiomyopathies, Cytochrome P450 Bioactive Lipids in the Heart, Epoxide Hydrolase and Leukotoxin in the Heart and Lung, Role of cytochrome P450-epoxygenase and soluble epoxide hydrolase in the regulation of vascular response, Bioactive Lipids in Hypertension, Cytochrome P450 Metabolites and Angiogenesis, 20-Hydroxyeicosatetraenoic Acid and Vascular Function, and more.
Other critical sections cover Cytochrome P450 Eicosanoids and the Brain, Omega-3 Oxylipids, Resolvins, Lipoxins and Inflammation, Endocannabinoids as Bioactive Metabolites, and Oxylipins and Aspirin Exacerbated Respiratory Disease.
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Table of Contents
PrefaceDarryl C. Zeldin and John Seubert
1. Bioactive lipids in hypertension
John D. Imig
2. Role of cytochrome P450-epoxygenase and soluble epoxide hydrolase in the regulation of vascular response
Mohammed A. Nayeem, Werner J. Geldenhuys and Ahmad Hanif
3. Cyclooxygenases, eicosanoids and platelets
Annalisa Bruno, Stefania Tacconelli, Annalisa Contursi, Patrizia Ballerini and Paola Patrignani
4. The roles of eicosanoids in myocardial diseases
Zuowen He and Dao Wen Wang
5. Cardioprotective mechanisms of cytochrome P450 derived oxylipins from ?-3 and ?-6 PUFAs
Christi Cho, Theresa Aliwarga, Alexandra M. Wiley and Rheem A. Totah
6. 20-Hydroxyeicosatetraenoic acid (20-HETE): Bioactions, receptors, vascular function, cardiometabolic disease and beyond
Jonathan V. Pascale, Alexandra Wolf, Yonaton Kadish, Danielle Diegisser, Melissa-Maria Kulaprathazhe, Danait Yemane, Samir Ali, Namhee Kim, David E. Baruch, Muhamad Afiq Faisal Bin Yahaya, Ercument Dirice, Adeniyi M. Adebesin, John R. Falck, Michal L. Schwartzman and Victor Garcia
7. Insights into the role of the resolvin D2-GPR18 signaling axis in cardiovascular physiology and disease
Matthew Spite and Gabrielle Fredman
8. Cytochrome P450-derived eicosanoids in brain: From basic discovery to clinical translation
Catherine M. Davis, Aseel H. Ibrahim and Nabil J. Alkayed
9. Lipid mediators generated by the cytochrome P450: Epoxide hydrolase pathway
Timo Fr?mel, Jiong Hu and Ingrid Fleming
10. Role of omega-3 and omega-6 endocannabinoids in cardiopulmonary pharmacology
Tiffany Y.-C. Tang, Justin S. Kim and Aditi Das
11. Oxylipins in nonsteroidal anti-inflammatory drug-exacerbated respiratory disease (N-ERD)
Kimberley Cousins, Chien-Chang Chen, Esha Sehanobish and Elina Jerschow
