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Microfluidics-Aided Technologies. Platforms for Next Generation Biological Applications

  • Book

  • December 2024
  • Elsevier Science and Technology
  • ID: 5723981

Microfluidics-Aided Technologies: Platforms for Next Generation Biological Applications aims to provide comprehensive information of microfluidic technologies, their development and biomedical applications. The book opens with an overview of the fundamentals of microfluidics. It is followed by discussions of methods and biomedical applications of microfluidics in diagnostics, prognostics, cell engineering, gene sequencing, cellular analysis, and bioimaging. The book also explores breakthroughs in microfluidics such as 3D bioprinting, organ-on-chip technologies, and regenerative medicine. This book offers researchers an interdisciplinary perspective towards biological problems. It is a resource for advanced undergraduate, graduate students, researchers and industry scientists interested in the emergence of advance techniques and next generation microfluidics-aided technologies for applications in the biomedical and medical research.

Table of Contents

Section 1: Introduction to Micro-scale flow enabled systems 1. Fundamentals of Microfluidics 2. Mathematical modelling in microfluidics for biosystems 3. Breakthroughs and Current Limitations in microfluidic systems Section 2: Methods and Applications of Microfluidics I 4. Microfluidic Systems in Prognostics and Diagnostics 5. Microfluidics in drug screening and drug delivery 6. Microfluidics assisted cell engineering and manipulation 7. Microfluidics assisted Cellular Analysis 8. Microfluidics in Bioimaging in vivo and in vitro advancements Section 3: Methods and Applications of Microfluidics II 9. Genetic sequencing and editing using microfluidics (system on chip approach) 10. Anaphylactic detection using microfluidic systems 11. Microfluidic systems for bacterial and fungal research 12. Microfluidics in studying disease biology and disease modelling in vitro 13. Microfluidics in bioanalytical chemistry Section 4: Breakthroughs in Microfluidics 14. Role of Microfluidics in 3D bioprinting 15. Tissue-on-Chip, Organ-on-chip and Organism-on-chip 16. Microfluidics in Regenerative medicine 17. Microfluidics in Protein engineering 18. Microfluidics-enabled Multi-omics analysis system Section 5: Microfluidics and its applications in Microbe and Plant study 19. Microfluidics assisted study of plant biomechanics 20. Plant-on-chip (root chips, shoot chips, apical chips) 21. Microfluidic device to study the effect of chemical and mechanical cues on cells 22. Investigating diatoms in a microenvironment using microfluidics

Authors

Dhananjay Bodas Scientist, Nanobioscience Group, Agharkar Research Institute India, Pune, India. Dr. Dhananjay Bodas completed his doctoral research in the field of Microelectronics from the Department of Electronic Science, University of Pune in 2004. He is a recipient postdoctoral awards from the Defense ministry of France and the prestigious Alexander von Humboldt Foundation in 2004 and 2006, respectively. He is currently working as a Scientist E in the Nanobioscience Group at the Agharkar Research Institute in Pune, India. He works at the interface of microtechnology, surface chemistry, and application biology. Current areas of interest are understanding flows at microscale by fabricating devices using unconventional techniques and the development of ultra-sensitive and specific diagnostic platforms to detect pathogens and development of organ-on-chip platforms. Virendra Gajbhiye Scientist in Nanomedicine, Agharkar Research Institute, Pune, India. Dr. Virendra Gajbhiye has been working in the field of nanomedicine for the last 15 years. He has a doctoral degree (Ph.D.) in Pharmaceutical Science with post-doctoral research experience at University of Wisconsin-Madison and Oregon Health and Sciences University. Since 2013 he is working as a Scientist in Nanomedicine at Agharkar Research Institute, Pune, India. He has worked extensively with polymeric nanoparticles specially dendrimers and mesoporous silica nanoparticles. His research interest lies in Nanomedicine, Targeted drug and siRNA delivery, Biomedical application of dendrimers, Biomaterials unimolecular micelles and imaging, Multifunctional polymeric nanoparticles, Nanoparticles in tissue engineering.