Epigenetics in Health and Disease, Volume 197 in the Progress in Molecular Biology and Translational Science series, highlights new advances in the field, with this new volume presenting interesting chapters on An Introduction to epigenetics in health and disease, State-of-the-art techniques for epigenetics study, Computational biology in epigenetics, Artificial intelligence and machine learning in epigenetics, CRISPR-Cas systems in epigenetics modification for health, Mechanisms of DNA methylation and histone modifications, Non-coding RNA in epigenetics, Role of DNA Methylation in cardiovascular diseases, Role of epigenetics in renal diseases, and much more.
Additional chapters update on Histone modifications in fat metabolism and obesity, Role of DNA methylation in diabetes and obesity, Epigenetic regulons in Alzheimer's disease, Epigenetics in heredity disease, Epigenetics of aging, Epigenetics in cancer development, diagnosis and therapy, Microbiota and epigenetics: health impact, Epigenetics in Fetal Alcohol Spectrum disorder, and much more.
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Table of Contents
PrefaceIndra Mani and Vijai Singh
1. Insight into epigenetics and human diseases
Ankita Saini, Adya Varshney, Ashok Saini and Indra Mani
2. State-of-the-art techniques to study epigenetics
Ashok Saini, Yashaswi Rawat, Kritika Jain and Indra Mani
3. Mechanisms of DNA methylation and histone modifications
Santoshi Acharjee, Shraddha Chauhan, Rajshree Pal and Raghuvir Singh Tomar
4. Epigenetics, genomics imprinting and non-coding RNAs
Gautham Manoj, Anjali Krishna, Anandhu Presannan, Nidheesh M, Renuka Suravajhala and Prashanth Suravajhala
5. Epigenetics in cardiovascular health and disease
Nicholas W.S. Chew, Shaun Loong and Roger Foo
6. Histone modifications in fat metabolism and obesity
Dinh-Toi Chu, Yen-Vy Nguyen Thi and Nicholas W.S. Chew
7. Role of DNA methylation in diabetes and obesity
Dinh-Toi Chu, Nhat-Le Bui, Hue Vu Thi and Yen Vy Nguyen Thi
8. Epigenetic regulation of aging
Sarita Mishra, Mahima Raval, Akanksha Singh Kachhawaha, Budhi Sagar Tiwari and Anand Krishna Tiwari
9. Epigenetics in fetal alcohol spectrum disorder
Balapal S. Basavarajappa
10. Epigenetic regulation of pluripotency inducer genes NANOG and SOX2 in human prostate cancer
Niharika, Ankan Roy, Jagdish Mishra, Subhajit Chakraborty, Suraj Pratap Singh and Samir Kumar Patra
11. Mechanistic aspects of reversible methylation modifications of arginine and lysine of nuclear histones and their roles in human colon cancer
Ankan Roy, Niharika, Subhajit Chakraborty, Jagdish Mishra, Suraj Pratap Singh and Samir Kumar Patra
