-
Emphasizes clinical aspects of immunology, including disease pathogenesis, the development of novel therapies based on basic science, and an appendix of clinical cases for real-world application.�
-
Contains new and expanded content on pandemics, COVID-19, and herd immunity; resistance and susceptibility to COVID-19; RNA vaccines and hybrid viral vaccines; tumor immunotherapy; innate immune responses to viruses; mechanisms of immunologic tolerance; and immunotherapy for autoimmune, allergic, and other inflammatory diseases, and cancer.�
-
Provides unrivalled instruction from an expert author team, all of whom are experienced teachers, course directors, and lecturers.�
-
Features a highly readable writing style and practical organization, now with fully revised content and updated images to cover new information and improve reader understanding of complex concepts.�
-
Provides additional online features such as answers to in-book chapter review questions and self-assessment questions.�
-
Presents information in a format and style that maximizes usefulness to students and teachers of medicine, allied health fields, and biology.�
-
Contains numerous features designed to help students understand key immunologic concepts: high-quality illustrations, practical tables, chapter outlines, bolded key points, and focus questions in every chapter for self-assessment and review.�
-
An eBook version is included with purchase. The eBook allows you to access all the text and figures, with the ability to search, customize your content, make notes and highlights, and have content read aloud.�
Table of Contents
1 Introduction to the Immune System Nomenclature, General Properties, and Components 2 Innate Immunity The Early Defense Against Infections 3 Antigen Capture and Presentation to Lymphocytes What Lymphocytes See 4 Antigen Recognition in the Adaptive Immune System Structure of Lymphocyte Antigen Receptors and Development of Immune Repertoires 5 T Cell-Mediated Immunity Activation of T Lymphocytes 6 Effector Mechanisms of T Cell-Mediated Immunity Functions of T Cells in Host Defense 7 Humoral Immune Responses Activation of B Lymphocytes and Production of Antibodies 8 Effector Mechanisms of Humoral Immunity Elimination of Extracellular Microbes and Toxins 9 Immunological Tolerance and Autoimmunity Self-Nonself Discrimination in the Immune System and Its Failure 10 Immune Responses Against Tumors and Transplants Immunity to Noninfectious Transformed and Foreign Cells 11 Hypersensitivity Disorders Caused by Immune Responses 12 Congenital and Acquired Immunodeficiencies Diseases Caused by Defective Immunity Selected Readings Appendix I Glossary Appendix II Cytokines Appendix III Principal Features of Selected CD Molecules APPENDIX IV Clinical Cases
