“Zamicastat Emerging Drug Insight and Market Forecast - 2032” report provides comprehensive insights about Zamicastat for Pulmonary Arterial Hypertension in the 7MM. A detailed picture of the Zamicastat for Pulmonary Arterial Hypertension in the 7MM, i.e., United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan, for the study period 2019-2032 is provided in this report along with a detailed description of the Zamicastat for Pulmonary Arterial Hypertension. The report provides insight about mechanism of action, dosage and administration, as well as research and development activity including regulatory milestones, along with other developmental activities. Further, it also consists of future market assessments inclusive of the Zamicastat market forecast, analysis for Pulmonary Arterial Hypertension in the 7MM, descriptive analysis such as SWOT, analyst views, comprehensive overview of market competitors, and brief about emerging therapies in Pulmonary Arterial Hypertension.
Dopamine β hydroxylase (DBH) - a key player in the catecholamine biosynthetic pathway - may provide a therapeutic opportunity and should be extensively explored as a target for potent anti-hypertensive.
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Drug Summary
Zamicastat (BIA 5-1058) is a dopamine β-hydroxylase (DBH) inhibitor that modulates sympathetic drive by preventing the conversion of dopamine to norepinephrine (NE) in sympathetically innervated tissues. Sympathetic nervous system (SNS) activation contributes to clinical deterioration in pulmonary arterial hypertension. The drug can cross the blood-brain barrier (BBB) to cause both central and peripheral effects. It is also a concentration-dependent dual P-gp and BCRP inhibitor with IC50 values of 73.8 μM and 17.0 μM, respectively.Dopamine β hydroxylase (DBH) - a key player in the catecholamine biosynthetic pathway - may provide a therapeutic opportunity and should be extensively explored as a target for potent anti-hypertensive.
Scope of the Report
The report provides insights into:
- A comprehensive product overview including the Zamicastat description, mechanism of action, dosage and administration, research and development activities in Pulmonary Arterial Hypertension.
- Elaborated details on Zamicastat regulatory milestones and other development activities have been provided in this report.
- The report also highlights the Zamicastat research and development activity in Pulmonary Arterial Hypertension details across the United States, Europe and Japan.
- The report also covers the patents information with expiry timeline around Zamicastat.
- The report contains forecasted sales of Zamicastat for Pulmonary Arterial Hypertension till 2032.
- Comprehensive coverage of the late-stage emerging therapies for Pulmonary Arterial Hypertension.
- The report also features the SWOT analysis with analyst views for Zamicastat in Pulmonary Arterial Hypertension.
Methodology
The report is built using data and information sourced primarily from internal databases, primary and secondary research and in-house analysis by the research team of industry experts. Information and data from the secondary sources have been obtained from various printable and nonprintable sources like search engines, news websites, global regulatory authorities websites, trade journals, white papers, magazines, books, trade associations, industry associations, industry portals and access to available databases.Zamicastat Analytical Perspective
In-depth Zamicastat Market Assessment
This report provides a detailed market assessment of Zamicastat in Pulmonary Arterial Hypertension in the 7MM, i.e., United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan. This segment of the report provides forecasted sales data for from 2024 to 2032.Zamicastat Clinical Assessment
The report provides the clinical trials information of Zamicastat for Pulmonary Arterial Hypertension covering trial interventions, trial conditions, trial status, start and completion dates.Report Highlights
- In the coming years, the market scenario for Pulmonary Arterial Hypertension is set to change due to the extensive research and incremental healthcare spending across the world; which would expand the size of the market to enable the drug manufacturers to penetrate more into the market.
- The companies are developing therapies that focus on novel approaches to treat/improve the disease condition, assess challenges, and seek opportunities that could influence Zamicastat dominance.
- Other emerging products for Pulmonary Arterial Hypertension are expected to give tough market competition to Zamicastat and launch of late-stage emerging therapies in the near future will significantly impact the market.
- A detailed description of regulatory milestones, and developmental activities, provide the current development scenario of Zamicastat in Pulmonary Arterial Hypertension.
- This in-depth analysis of the forecasted sales data of Zamicastat from 2024 to 2032 will support the clients in the decision-making process regarding their therapeutic portfolio by identifying the overall scenario of the Zamicastat in Pulmonary Arterial Hypertension.
Key Questions Answered
- What is the product type, route of administration and mechanism of action of Zamicastat?
- What is the clinical trial status of the study related to Zamicastat in Pulmonary Arterial Hypertension and study completion date?
- What are the key collaborations, mergers and acquisitions, licensing and other activities related to the Zamicastat development?
- What are the key designations that have been granted to Zamicastat for Pulmonary Arterial Hypertension?
- What is the forecasted market scenario of Zamicastat for Pulmonary Arterial Hypertension?
- What are the forecasted sales of Zamicastat in the 7MM, including the United States, Europe (Germany, France, Italy, Spain, and the United Kingdom), and Japan?
- What are the other emerging products available in Pulmonary Arterial Hypertension and how are they giving competition to Zamicastat for Pulmonary Arterial Hypertension?
- Which are the late-stage emerging therapies under development for the treatment of Pulmonary Arterial Hypertension?
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Table of Contents
1. Report Introduction2. Zamicastat Overview in Pulmonary Arterial Hypertension
2.1 Product Detail
2.2 Clinical Development
2.2.1 Clinical Studies
2.2.2 Clinical Trials Information
2.3 Other Development Activities
2.4 Product Profile
3. Competitive Landscape (Marketed Therapies)
4. Competitive Landscape (Late-stage Emerging Therapies)*
5. Zamicastat Market Assessment
5.1 Market Outlook of Zamicastat in Pulmonary Arterial Hypertension
5.2 7MM Market Analysis
5.2.1 Market Size of Zamicastat in the 7MM for Pulmonary Arterial Hypertension
5.3 Country-wise Market Analysis
5.3.1 Market Size of Zamicastat in the United States for Pulmonary Arterial Hypertension
5.3.2 Market Size of Zamicastat in Germany for Pulmonary Arterial Hypertension
5.3.3 Market Size of Zamicastat in France for Pulmonary Arterial Hypertension
5.3.4 Market Size of Zamicastat in Italy for Pulmonary Arterial Hypertension
5.3.5 Market Size of Zamicastat in Spain for Pulmonary Arterial Hypertension
5.3.6 Market Size of Zamicastat in the United Kingdom for Pulmonary Arterial Hypertension
5.3.7 Market Size of Zamicastat in Japan for Pulmonary Arterial Hypertension
6. SWOT Analysis
7. Analysts’ Views
8. Appendix
8.1 Bibliography
8.2 Report Methodology
9. Publisher Capabilities
10. Disclaimer
11. About the Publisher
12. Report Purchase Option
List of Tables
Table 1: Zamicastat: Clinical Trial Description, 2022
Table 2: Zamicastat: General Description
Table 3: Competitive Landscape ( Marketed Therapies)
Table 4: Competitive Landscape (Emerging Therapies)
Table 5:Zamicastat Market Size in the 7MM, in USD million (2019-2032)
Table 6:Zamicastat Market Size in the United States, in USD million (2019-2032)
Table 7:Zamicastat Market Size in Germany, in USD million (2019-2032)
Table 8:Zamicastat Market Size in France, in USD million (2019-2032)
Table 9:Zamicastat Market Size in Italy, in USD million (2019-2032)
Table 10:Zamicastat Market Size in Spain, in USD million (2019-2032)
Table 11:Zamicastat Market Size in the United Kingdom, in USD million (2019-2032)
Table 12:Zamicastat Market Size in Japan, in USD million (2019-2032)
List of Figures
Figure 1: Market Size of Zamicastat in the 7MM, in USD million (2019-2032)
Figure 2: Market Size of Zamicastat in the United States, in USD million (2019-2032)
Figure 3: Market Size of Zamicastat in Germany, in USD million (2019-2032)
Figure 4: Market Size of Zamicastat in France, in USD million (2019-2032)
Figure 5: Market Size of Zamicastat in Italy, in USD million (2019-2032)
Figure 6: Market Size of Zamicastat in Spain, in USD million (2019-2032)
Figure 7: Market Size of Zamicastat in the United Kingdom, in USD million (2019-2032)
Figure 8:Market Size of Zamicastat in Japan, in USD million (2019-2032)