Digestive Enzymes Market Report 2025

This Digestive Enzymes market report provides a comprehensive analysis of the market’s characteristics, size, and growth, including segmentation, regional and country-level breakdowns, competitive landscape, market shares, trends, and strategies. It also tracks historical and forecasted market growth across various geographies.

The digestive enzymes market size has grown rapidly in recent years. It will grow from $1.09 billion in 2024 to $1.2 billion in 2025 at a compound annual growth rate (CAGR) of 10.7%. The growth in the historic period can be attributed to increasing digestive health awareness, changing dietary habits, aging population, gastrointestinal disorders, nutraceutical industry growth, research and development, e-commerce expansion.

The digestive enzymes market size is expected to see rapid growth in the next few years. It will grow to $1.96 billion in 2029 at a compound annual growth rate (CAGR) of 13%. The growth in the forecast period can be attributed to health-conscious consumers, mainstream healthcare integration, plant-based and natural products. Major trends in the forecast period include innovation in formulations, customized enzyme formulations, clean label and natural ingredients, personalized nutrition and testing, research and innovation.

The growing prevalence of gastrointestinal disorders across various age groups is a significant factor propelling the expansion of the digestive enzymes market. These disorders encompass a wide range of issues in the gastrointestinal tract, from the mouth to the anus, often resulting from an insufficient supply of digestive enzymes. To manage these conditions, individuals often need to orally consume digestive enzymes in the form of dietary supplements or medications. The surge in gastrointestinal disorders can be attributed to factors such as smoking, dietary choices, genetic predisposition, hygiene practices, increased antibiotic use, and the effects of industrialization and urbanization on the environment. According to a survey by the American Gastroenterological Association in September 2022, approximately 60-70 million Americans are grappling with gastrointestinal diseases that can significantly disrupt their daily lives. The data also reveals that nearly 40% of Americans had to curtail their routine activities in the past year due to uncomfortable bowel symptoms, with a higher prevalence of functional gastrointestinal disorders (FGID) among women. This issue is not limited to the United States, as a large-scale multinational study found that over 40% of the global population is affected by FGIDs. Consequently, the rising incidence of digestive diseases is a key driver of growth in the digestive enzymes market.

The escalation of unhealthy lifestyles is another factor contributing to the expansion of the digestive enzymes market. Unhealthy habits, including poor dietary choices, lack of physical activity, excessive alcohol consumption, smoking, and inadequate sleep, elevate the risk of chronic diseases and overall health deterioration. Digestive enzymes play a crucial role in mitigating the adverse effects of an unhealthy lifestyle by improving digestion and nutrient absorption, thereby promoting digestive health. For instance, in July 2023, data from the NIH, a U.S.-based government agency, revealed a high prevalence of unhealthy lifestyle habits among participants, with 86.4% reporting poor dietary habits, 14.5% engaging in excessive alcohol consumption, 6% using tobacco, 72.2% lacking sufficient physical activity, 42.3% experiencing excessive screen time, and 63.9% reporting inadequate sleep duration. This growing trend of unhealthy lifestyles is expected to drive the expansion of the digestive enzymes market.

To address the diverse needs of consumers, companies in the digestive enzymes market are actively investing in the development of tailored digestive enzymes. These condition-specific enzymes are designed to support the digestion of individuals with specific sensitivities and may contain a combination of enzymes in a single product. For instance, Sabinsa, a U.S.-based provider of herbal extracts, cosmeceuticals, minerals, and dietary supplements, has formulated DigeZyme, a multi-enzyme complex comprising five different enzymes - cellulase, lactase, amylase, lipase, and protease. This product is widely used by individuals who struggle to digest carbohydrates, fats, and proteins. The emphasis on creating customized digestive enzymes is on the rise within the industry.

Leading companies in the digestive enzymes market are focusing on developing innovative solutions, such as enzymatic digestibility enhancers, to address the growing consumer demand for healthier alternatives. Enzymatic digestibility enhancers are substances or supplements containing enzymes designed to improve nutrient breakdown and absorption from food. For example, in September 2023, Huvepharma EOOD, a Bulgaria-based pharmaceutical company, launched its enzymatic digestibility enhancer, Huvezym neXo, in the European Union. This product, part of the Huvezym brand, is formulated with a complex of enzymes that enhance nutrient absorption by reducing intestinal viscosity, de-encapsulating nutrients, and releasing prebiotic oligosaccharides. Trial results indicate that Huvezym neXo can increase growth rates by 4.4% and improve feed conversion by 3.5%.

In August 2022, BioIVT, a U.S.-based biological products company, acquired Cypex for an undisclosed amount. This acquisition allows BioIVT to strengthen its product portfolio by incorporating advanced drug metabolism technologies and expanding its global presence to better serve the biopharmaceutical research community. Cypex, a UK-based manufacturer, specializes in producing enzymes that improve nutrient absorption and address digestive issues by breaking down proteins, fats, and carbohydrates, thereby promoting overall digestive health.

Digestive enzymes are substances that play a crucial role in the digestive process by facilitating the breakdown of food. These proteins expedite the chemical reactions necessary to convert food into compounds that can be absorbed by the digestive system. They are produced and released by various glands and cells in the body, including the salivary glands, the stomach lining, the pancreas, and the small intestine.

The primary categories of digestive enzymes include those involved in carbohydrate digestion, protease enzymes that assist in breaking down proteins, lipase enzymes that aid in the digestion of fats, and various other enzyme types. Lipase, for example, is a protein generated by the pancreas, a small organ situated near the stomach, and it specifically supports the digestion of dietary fats. Digestive enzymes can be derived from various sources, including animals, fungi, microorganisms, and plants, and they find applications in treating conditions such as indigestion, chronic pancreatitis, irritable bowel syndrome, and other digestive disorders. These products are typically available through different distribution channels, including retail stores and online outlets.

The digestive enzymes market research report is one of a series of new reports that provides digestive enzymes market statistics, including digestive enzymes industry global market size, regional shares, competitors with a digestive enzymes market share, detailed digestive enzymes market segments, market trends and opportunities, and any further data you may need to thrive in the digestive enzymes industry. These digestive enzymes market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.

Major companies operating in the digestive enzymes market include Garden of Life LLC, Biotics Research Corporation, Klaire Laboratories, Abbott Nutrition, AbbVie Inc., Johnson & Johnson Inc., Amway Corporation, Food State Inc., Matsun Nutrition, Metagenics Inc., Twinlab Corporation, AST Enzymes, Vemo Corp., Advanced Vital Enzymes Pvt. Ltd., Zeus Biotech Limited, Vox Nutrition Inc., Enzyme Bioscience Pvt. Ltd., XYMOGEN Inc., Douglas Laboratories, Thorne Research Inc., Integrative Therapeutics LLC, Pure Encapsulations Inc., Ortho Molecular Products Inc., Designs for Health Inc., Master Supplements Inc., Proteozymes Pvt Ltd., Chr. Hansen Holding A/S, Danone S.A., DSM Nutritional Products AG, DuPont de Nemours Inc., Kerry Group plc, Koninklijke DSM N.V., Lonza Group AG, Nestle S.A., Pfizer Inc., Sanofi S.A., Specialty Enzymes & Biotechnologies Co., Thermo Fisher Scientific Inc., Wacker Chemie AG.

North America was the largest region in the digestive enzymes market in 2024. Middle East is expected to be the largest growing region in the digestive enzymes market report during the forecast period. The regions covered in the digestive enzymes market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa. The countries covered in the digestive enzymes market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Italy, Spain, Canada.

The digestive enzymes market consists of sales of amylase, maltase, and lactase. Values in this market are factory gate values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

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