Chromatography Resins Market Report 2025

The chromatography resins market size has grown strongly in recent years. It will grow from $2.95 billion in 2024 to $3.21 billion in 2025 at a compound annual growth rate (CAGR) of 8.8%. The growth in the historic period can be attributed to increased biopharmaceutical production, growth in analytical and research applications, pharmaceutical industry growth, increased academic and clinical research, growth of the phramaceutical industry.

The chromatography resins market size is expected to see rapid growth in the next few years. It will grow to $4.86 billion in 2029 at a compound annual growth rate (CAGR) of 10.9%. The growth in the forecast period can be attributed to increasing drug development, precision medicine research, regulatory and quality standards, emerging market growth, growing green chemistry initiatives. Major trends in the forecast period include introduction of separation technologies, technological advancements, customized resin solutions, industrial and biotechnology innovations, and advanced chromatography techniques.

Rising investments in the healthcare sector are anticipated to drive the growth of the chromatography resin market in the future. Healthcare investments refer to the financial resources allocated to the healthcare industry, including funding for medical research, development of new healthcare technologies, and improvements to infrastructure. Investments in chromatography resins fuel research and development, leading to enhanced purification processes and more efficient drug production, ultimately promoting healthcare innovation and increasing drug availability. For example, in August 2024, the Bio Industry Association, a UK-based trade association, reported that the life sciences and biotech sector surpassed the total amount raised in 2023. The sector raised $2.574 billion in the first and second quarters of 2024, exceeding the $2.34 billion raised the previous year. The second quarter of 2024 saw a 135% increase in venture capital funding, amounting to $733 million compared to $312 million in Q1. This marks the highest quarterly funding since Q3 2021 and stands in stark contrast to the global decline in venture capital funding for biotech observed in Q1 2023. Thus, the increasing investments in the healthcare sector are propelling the growth of the chromatography resin market.

The chromatography resin market is poised for growth due to increasing investments in the healthcare sector. Healthcare investments encompass financial resources directed towards medical research, the development of new healthcare technologies, and infrastructure enhancements. The injection of funds into chromatography resins in the healthcare sector facilitates research and development activities, leading to enhanced purification processes and more efficient drug production. A notable example is the data reported by Silicon Valley Bank in 2022, indicating a record $23.4 billion in private investments in the healthcare sector in the first quarter of 2021. This momentum continued into Q2 2021, with total healthcare investment reaching $47 billion in the first half of the year, more than double the pace observed in the same period in 2020. Consequently, the increasing investments in the healthcare sector are instrumental in propelling the growth of the chromatography resin market.

Key companies in the chromatography resins market are developing technologically advanced solutions, including protein A chromatography resins, to provide high specificity and efficiency in antibody purification. Protein A chromatography resin is a specialized resin utilized in affinity chromatography to purify antibodies by binding to the Fc region of immunoglobulins, particularly IgG, due to its strong affinity for Protein A. For example, in June 2024, Ecolab Inc., a US-based chemical company, introduced DurA Cycle, a protein A chromatography resin designed for large-scale purification processes. DurA Cycle is specifically created for the large-scale commercial production of monoclonal antibodies, where managing the cost of goods is crucial for biologic drug developers. This innovative resin enables biologic manufacturers to improve production efficiencies, reduce costs, and accelerate the introduction of new treatments to the clinic.

Prominent companies in the chromatography resin market are strategically intensifying their focus on the introduction of high-performance resins as a means to establish a competitive advantage. These specialized materials play a crucial role in chromatography, a laboratory technique utilized for the separation and analysis of complex substance mixtures. As an illustration, in February 2022, Repligen, a bioprocessing company based in the United States, unveiled three advanced affinity chromatography resins designed for gene therapy purification, namely AVIPure-AAV9, AVIPure-AAV8, and AVIPure-AAV2. Specifically tailored for the major adeno-associated virus (AAV) gene therapy vectors in use today, these resins are integral to the primary platform for gene delivery in treating various human diseases. Notably, they offer capture-step purification of AAV 2, 8, and 9 vectors, featuring potential alkaline clean-in-place regeneration. These resins provide high performance at a competitive price point, surpassing or meeting the performance metrics of resins developed on alternative platforms, along with the added advantage of robust alkaline stability.

In June 2023, Biotage, a life sciences company based in Sweden, acquired Astrea Bioseparations for an undisclosed amount. This acquisition is intended to broaden the company’s franchise into the rapidly growing and larger bioprocessing segment, while also increasing its exposure to biologics and advanced therapeutic customers. Additionally, it enhances Biotage's pipeline with a wealth of upcoming product launches across chromatography resins, nanofiber-based membranes, and columns. Astrea Bioseparations is a manufacturer of chromatography resins located in the UK.

Major companies operating in the chromatography resins market include Merck KGaA, Bio-Rad Laboratories Inc., GE Healthcare Life Sciences, Thermo Fisher Scientific Inc., Purolite Corporation, W. R. Grace and Company, Mitsubishi Chemical Corporation, Tosoh Corporation, Danaher Corporation, Repligen Corporation, Pall Corporation a Danaher operating company under the Cytiva brand, Cytiva a Danaher operating company, Bio-Works Technologies AB, Agilent Technologies Inc., Avantor Inc., Waters Corporation, Nouryon Holding B.V., ChromaTan Corporation, BIA Separations GmbH, KANEKA Corporation, Sepax Technologies Inc., YMC Co Ltd., Phenomenex Inc.

Chromatography resins play a crucial role in capturing and refining biomolecules like monoclonal antibodies, antibody fragments, vaccines, and other substances using a stationary phase. The purification process is driven by a mobile phase that propels the sample and chromatography resins through the stationary phase.

There are two main types of chromatography resins such as native and synthetic. Native resins are crafted from natural polymers like agarose, cellulose, and dextran. Various technology types, including affinity chromatography, anion exchange chromatography, cation exchange chromatography, size exclusion, and hydrophobic interaction, are employed in diverse applications such as pharmaceuticals, biotechnology, food and beverage, as well as water and environmental analysis.

The chromatography resins market research report is one of a series of new reports that provides chromatography resins market statistics, including chromatography resins industry global market size, regional shares, competitors with a chromatography resins market share, detailed chromatography resins market segments, market trends and opportunities, and any further data you may need to thrive in the chromatography resins industry. This chromatography resins market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.

North America was the largest region in the chromatography resins market in 2024. Asia-Pacific is expected to be the fastest-growing region in the market. The regions covered in the chromatography resins market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, the Middle East, and Africa.

The countries covered in the chromatography resins market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA.

The chromatography resins market consists of sales of affinity resins and ion exchange resin. Values in this market are ‘factory gate’ values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

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