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Brings you fully up to date with recent advances, including new molecular information for breast entities, new surgical techniques, more widely used multigene prognostic tests, and assays used to determine treatment, such as PD-L1 as a new immunotherapy biomarker for triple-negative breast cancer.�
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Incorporates the latest classifications of breast pathology and molecular diagnosis.�
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Organizes each topical chapter around relevant genomic and molecular information, clinical presentation, gross and microscopic pathologic findings and diagnostic and molecular immunohistochemistry.�
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Maps immunohistochemistry for each entity according to diagnostic, theranostic, and genomic applications, with specific regard to disease entities in each chapter.�
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Discusses breast specimen handling in detail to assure proper sampling and processing for optimal molecular and immunohistochemistry resulting.�
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Supplies a convenient quick reference at the beginning of each chapter that includes all relevant diagnostic, theranostic, and genomic data for fast retrieval.�
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Features approximately 2,000 full-color pathological images that clearly depict clinical, radiological, molecular, immunohistochemical, and theranostic aspects of disease.�
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Includes biomarker guideline updates throughout.�
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Reflects updates to new tumor staging data in the American Joint Committee on Cancer (AJCC) 8th Edition and updated ASCO/CAP guidelines for interpreting HER2 assays.��
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Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.�
Table of Contents
- Normal Breast and Developmental Disorders
- Reactive and Inflammatory Conditions of the Breast
- Infections of the Breast
- Epidemiology of Breast Cancer and Pathology of Heritable Breast Cancer
- Patient Safety in Breast Pathology
- Gross Examination of Breast Specimens
- Sentinel Lymph Node Biopsy
- Breast Imaging Modalities for Pathologists
- Predictive and Prognostic Marker Testing in Breast Pathology: Immunophenotypic Subclasses of Disease
- Molecular-Based Testing in Breast Disease for Therapeutic Decisions
- Diagnostic Immunohistology of the Breast
- Fibroepithelial Lesions
- Papilloma and Papillary Lesions
- Adenosis and Microglandular Adenosis
- Nipple Adenoma (Florid Papillomatosis of the Nipple)
- Radial Scar
- Myoepithelial Lesions of the Breast
- Fibrocystic Change and Usual Epithelial Hyperplasia of Ductal Type
- Columnar Cell Alterations, Flat Epithelial Atypia, and Atypical Ductal Epithelial Hyperplasia
- Molecular Classification of Breast Carcinoma
- Lobular Neoplasia and Invasive Lobular Carcinoma
- Ductal Carcinoma In Situ
- Invasive Ductal Carcinoma of No Special Type and Histologic Grade
- Triple-Negative and Basal-like Carcinoma
- Metaplastic Breast Carcinoma
- Apocrine Carcinoma of the Breast
- Paget Disease of the Breast
- Pathology of Neoadjuvant Therapeutic Response of Breast Carcinoma
- Special Types of Invasive Breast Carcinoma: Tubular Carcinoma, Mucinous Carcinoma, Cribriform Carcinoma, Micropapillary Carcinoma, Carcinoma with Medullary Features
- Rare Breast Carcinomas: Adenoid Cystic Carcinoma, Neuroendocrine Carcinoma, Secretory Carcinoma, Carcinoma with Osteoclast-like Giant Cells, Lipid-Rich Carcinoma, and Glycogen-Rich Clear Cell Carcinoma
- Mesenchymal Neoplasms of the Breast
- Neoplasia of the Male Breast
- Breast Tumors in Children and Adolescents
- Tumors of the Mammary Skin
- Hematopoietic Tumors of the Breast
- Metastatic Tumors in the Breast
- Next-Generation DNA Sequencing and the Management of Patients with Clinically Advanced Breast Cancer