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Offers an international perspective on the whole spectrum of the specialty, including a robust video library with demonstrations of key procedures and bronchoscopic views.�
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Uses a consistent format with succinct, bulleted text, and contains abundant tables and figures, chapter summaries, and more than 500 full-color images to convey key information in an easy-to-digest manner.�
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Contains eleven new chapters and discusses timely topics such as big data and -omics in respiratory disease, COVID-19, obesity and its consequences, and vaping and nicotine addiction among children and young people.�
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Provides up-to-date instruction on key procedures, such as bronchoscopy and pulmonary function testing.�
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Highlights the knowledge and expertise of nearly 90 new authors who are global experts in the fields of pediatrics, pulmonology, neurology, microbiology, cardiology, physiology, diagnostic imaging, critical care, otolaryngology, allergy, and surgery.�
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An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud.�
Table of Contents
Section 1: General Basic and Clinical Considerations
1. The History and Physical Examination
2. Molecular Determinants of Lung Morphogenesis
3. Basic Genetics and Epigenetics of Childhood Lung Disease
4. Environmental contributions to respiratory disease in children
5. The Surfactant System
6. The Structural and Physiologic Basis of Respiratory Disease
7. Biology and Assessment of Airway Inflammation
8. Lung Defenses: Intrinsic, Innate and adaptive
9. Bronchoscopy and Brochoalveolar Lavage in Pediatric Patients
10. Diagnostic Imaging of the Respiratory Tract
11. Pulmonary Function Tests in Infants and Preschool Children
12. Exercise and Lung Function in child health and disease
13. Integrating Patient reported outcomes into research and clinical practice
14. Transition from Pediatric to Adult Care
15. Long Term Consequences of Childhood Respiratory Disease
16. Drug Administration by inhalation in children
17. Physical Therapies in Pediatric Respiratory Disease
18. Congenital Lung Disease
19. Respiratory Disorders in the Newborn
20. Bronchopulmonary Dysplasia
21. Children Dependent on Respiratory Technology
Section 2: Infections of the Lung
22. Microbiological Diagnosis of Respiratory Illness: Recent advances
23. Acute Infections that produce upper airway obstruction
24. Bronchiolitis
25. Pneumonia in Children
26. Bronchiectasis and Chronic Suppurative Lung Disease
27. Influenza
28. New and Emerging Infections of the Lung
29. Tuberculosis
30. Non -Tuberculosis Mycobacterial Disease
31. The Mycoses
32. Pertussis and Other Bordetella Infections of the Respiratory Tract
33. Toxocariasis, Hydatid Disease of the Lung, Strongyloidiasis, and Pulmonary Paragonimiasis
Section 3: Pulmonary Disease in the Intensive Care Unit
34. Principles of mechanical ventilation
35. Childhood Pulmonary Arterial Hypertension
36. Pulmonary Edema
37. Respiratory Complications of Intensive Care
38. Acute Respiratory Distress Syndrome
39. Pulmonary Disease Associated with Congenital Heart Disease
40. Lung Injury from Hydrocarbon Aspiration and Smoke Inhalation
41. Drowning
Section 4: Asthma
42. The Epidemiology of Asthma
43. The Immunopathogenesis of Asthma
44. Asthma in the Preschool Age Child
45. Wheezing in Older Children: Asthma
46. Severe Asthma
47. The Influence of Upper Airway Disease on the Lower Airway
48. Modern Molecular Therapies for Application in Managing Childhood Asthma
Section 5: Cystic Fibrosis
49. Genetics and Pathophysiology of Cystic Fibrosis
50. Diagnosis and Presentation of Cystic Fibrosis
51. Pulmonary Disease in Cystic Fibrosis
52. Non-Pulmonary Manifestations of Cystic Fibrosis
53. Modern Molecular Therapies for CF
Section 6: Interstitial Lung Disease
54. New Concepts in Children's Interstitial Lung Disease and Diffuse Lung Disease
55. Rare and new childhood Lung Disorders
56. Childhood Interstitial Lung Disease Disorders More Prevalent in Infancy
57. Lung Diseases Associated with Disruption of Pulmonary Surfactant Homeostasis
58. Pulmonary Involvement in the Systemic Diseases of Childhood
59. Lung Injury Caused by Pharmacologic Agents
Section 7: Miscellaneous Disorders of the Lung
60. Pulmonary Embolism and Thromboembolic Disease
61. Diffuse Alveolar Hemorrhage in Children
62. The Lung in Sickle Cell Disease
63. Primary Immunodeficiency: and Other Diseases with Immune Disregulation
64. Pulmonary Disease in the Immunosuppressed Pediatric Patient
65. Hypersensitivity Pneumonitis and Eosinophilic Lung Diseases
66. Respiratory Disorders in HIV-Infected Children and Adolescents
67. Pediatric Lung Transplantation
68. Respiratory complication of Down Syndrome and other genetic syndromes
69. Air and Liquid in the Pleural Space
70. Atelectasis
71. Primary Ciliary Dyskinesia
72. Chest Wall and Respiratory Muscle Disorders
73. Disorders of the Respiratory Tract caused by trauma
74. Tumors of the Chest
Section 8: The Aerodigestive Model
75. The Aerodigestive Model
76. Aspiration
77. Feeding Swallowing and Voice Disorders
78. Gastroesophageal Reflux Disease and Eosinophilic Esophagitis in Children with Complex Airway Disease
79. Laryngeal and Tracheal Airway Disorders
80. Sudden Infant Death Syndrome and apparent life-threatening events
81. Disorders of Breathing During Sleep