Mechanisms of Disease Pathogenesis in Multiple Sclerosis summarizes our current understanding on MS and its clinical features and monitoring with available biomarkers, focusing on mechanisms that drive disease pathogenesis and their control by genetic, environmental factors and novel therapies for disease management. The book is written for neurologists, neuroimmunologists and clinical, translational and basic researchers interested in mechanisms of neurodegeneration. Multiple Sclerosis (MS) is an autoimmune disease which targets the central nervous system (CNS). It is the most common cause of non-traumatic neurological disability in young adults with a prevalence of 1 in 1000 and increasing, hence the importance of this book.
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Table of Contents
1. Multiple Sclerosis, clinical course, open questions and unmet clinical needs2. Novel Imaging Approaches in Multiple Sclerosis
3. Effect of infections on Multiple Sclerosis
4. T cells in Multiple Sclerosis.
5. B cells in Multiple Sclerosis.
6. Microglia in Multiple Sclerosis.
7. Monocytes in Multiple Sclerosis
8. Antigen Presenting Cells in Multiple Sclerosis.
9. Oligodendrocytes in Multiple Sclerosis.
10. Astrocytes in Multiple Sclerosis.
11. The Blood Brain Barrier in Multiple Sclerosis
12. Microbiome in Multiple Sclerosis.
