Smart Diagnostics for Neurodegenerative Disorders: Neuro-sensors explores all available biosensor-based approaches and technologies as well as their use in the diagnosis, prognosis and therapeutic management of a variety of neurological disorders such as Alzheimer's, Parkinson's and epileptic disorders. The book also discusses contemporary and revolutionary biosensor platforms that are being used to produce a quantitative quick lab-on-a-chip point-of-care (POC) assay for several types of predictive and diagnostic biomarkers linked with neurodegenerative disorders. It offers a combinatorial strategy for learning recent advances and designing new biosensor-based technologies in the fields of medical science, engineering and biomedical technology.
Early detection of neurological conditions has the potential to treat the disease and extend the life expectancy of patients. Recent improvements in biosensor-based approaches that target specific cell surface biomarkers can be used for early detection of neurodegenerative disease.
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Table of Contents
1 Neurobiosensors: novel approaches towards early diagnostics of neurodegenerative disorders2 Sampling methods and biomarkers for early detection of neurodegenerative disorders
3 Salivary biomarkers for neurodegenerative disorder for biomedical sensing
4 Lateral flow assay for early diagnosis of neurodegenerative disorder
5 Image processing: an early detection tool for Alzheimer's disease
6 Detection of genetic and epigenetic markers in neurodegenerative disorders
7 Electrochemical biosensor-based detection assays for early diagnosis of neurodegenerative disorders
8 FRET-based assays for neurological disease and diagnostics
9 Lab-on-chip platform for neurodegenerative disorder
10 Rapid diagnostic assays for the detection of Alzheimer's and Parkinson's diseases
11 Smartphone coupled nano-enabled sensors for neurodegenerative disorder
12 Microfluidic-integrated biosensors for neurodegenerative disorders
13 POCT devices for neurodegenerative disorders: from lab to clinics
14 Current challenges and future perspectives for the development of POCT devices for neurodegenerative disorders
Authors
Arpana Parihar Industrial Waste Utilization, Nano and Biomaterials, CSIR-Advanced, Materials and Processes, Research Institute (AMPRI), Bhopal, Madhya, Pradesh, India. Arpana Parihar is a DST Scientist B at CSIR-Advanced Materials and Processes Research Institute (AMPRI), Bhopal, India. She has 8 years of research and teaching experience and her current research interests include fabrication (Micro/Nano-fabrication) of Bio-devices/bio-medical POCT Devices for early diagnosis of cancer and infectious disease. She has gained significant expertise in the field of 3D cell culture, drug designing, tissue engineering, photodynamic therapy, molecular dynamic simulations, and immunoinformatics. Raju Khan Senior Principal Scientist & Professor, CSIR-Advanced Materials & Processes Research Institute, Bhopal, Madhya Pradesh, India.Raju Khan is a Senior Principal Scientist and Professor, at CSIR-Advanced Materials and Processes Research Institute, Bhopal. He did his PhD in Chemistry in 2005 from Jamia Millia Islamia, Central University, New Delhi, and Postdoctoral researcher at the "Sensor Research Laboratory� University of the Western Cape, Cape Town. His current research involved synthesizing novel materials to fabricate electrochemical and fluorescence-based biosensors integrated with microfluidics to detect target disease risk biomarkers for health care monitoring. He has published over 150 papers in SCI journal, which attracted over 5500 citations as per Google Scholar, published 45 book chapters in the reputed book Elsevier and Taylor Francis, editing of 28 books from Elsevier and Taylor Francis, and his research has been highlighted in Nature India. He has supervised 5 PhD and 30 undergraduate/postgraduate theses and has supervised 4 numbers of postdoctoral fellows under the scheme of N-PDF, CSIR-Nehru Fellowship, and DST-Women Scientist Projects.
Avanish Kumar Srivastava Director, CSIR-Advanced Materials and Processes Research Institute (AMPRI), Bhopal, Madhya Pradesh, India.Avanish Kumar Srivastava is the director of the CSIR-AMPRI, Bhopal, India. He is an expert in nanoscale measurements and instrumentation, and his research interests lie in nucleation growth, phase transformations, microstructures, and defects.
