Microbial biofilms are serious problem in medical settings as they are associated with significant mortality and morbidity. Infection related to biofilms not only increases recovery time, but also escalates the cost of disease management. Biofilms are intrinsically resistant to antibiotics and evade human defense mechanisms. In addition, the close proximity of microbes within biofilms promotes genetic transformation, facilitating the acquisition of antibiotic-resistant genes and leading to an increased prevalence of diseases associated with resistance. Fortunately, with advances in science and technology, novel strategies are being utilized to mitigate the impact of biofilms on human health. Microbial Biofilms: Role in Human Infectious Diseases focuses on new and emerging concepts in microbial biofilm research. It explores topics such as the mechanisms of biofilm formation, biofilm-induced pathogenesis, biofilm detection and diagnosis, gene exchange within biofilms, strategies to control microbial biofilms, and the burden of biofilm-associated infections. Additionally, the book highlights the various antibiofilm strategies, such as surface coating, signal quenching, novel compounds that can be translated to curb biofilm-associated infections, and the escalation of antimicrobial resistance determinants.
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Table of Contents
1. Bacterial Biofilms and infectious disease in human health: a concise review2. Microbial biofilms: Role of biofilms in recurrent orthopaedic infections
3. Dental biofilms: Application of nanoparticles to combat biofilms
4. Streptococcus biofilms, and their role in human infectious diseases
5. Surface coating: Strategy to prevent bacteria adhesion on medical implants
6. Bacterial biofilm a major challenge in medical indwelling devices
7. Single-species and multi-species biofilms causing infections
8. Effects of environmental factors to promote formation of biofilms by respiratory pathogens
9. Gut Microbiota: Role of biofilms in human health
10. Antimicrobial/antibiotic resistance of biofilms and factors contributing to resistance
11. Cell to cell interaction and cell signalling in biofilms
12. Microbial biofilms and the skin microbiome
13. Synthetic and phyto-compounds to combat microbial biofilms
14. Next generation sequencing: Role in microbial biofilms study
