Protein Purification and Isolation Global Market Report 2024

Protein purification and isolation involve the procedures used to separate a specific protein of interest from its surroundings, whether obtained from a cell culture in a laboratory or from the natural environment within a host organism. This process helps identify the existence of the protein from its source based on differences in their properties.

The main types of protein purification and isolation tools are instruments and consumables. Instruments are devices employed to carry out protein purification and isolation processes, which include extraction, precipitation, differential solubilization, ultracentrifugation, and various chromatographic methods. Technologies utilized in these processes encompass ultrafiltration, precipitation, preparative chromatography, electrophoresis, western blotting, dialysis and diafiltration, as well as centrifugation. The end-users of these technologies span academic medical institutes, hospitals and diagnostic centers, pharmaceutical and biotechnology companies, and contract research organizations. Applications for protein purification and isolation include drug screening, protein-protein interaction studies, biomarker discovery, target identification, protein therapeutics, disease diagnostics, and monitoring.

The protein purification and isolation market research report is one of a series of new reports that provides protein purification and isolation market statistics, including protein purification and isolation industry global market size, regional shares, competitors with an protein purification and isolation market share, detailed protein purification and isolation market segments, market trends and opportunities, and any further data you may need to thrive in the protein purification and isolation industry. This protein purification and isolation market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.

The protein purification and isolation market size has grown rapidly in recent years. It will grow from $8.66 billion in 2023 to $9.58 billion in 2024 at a compound annual growth rate (CAGR) of 10.5%. The growth observed in the historical period can be attributed to factors such as increased research and development in biopharmaceuticals, the growth of the biotechnology industry, rising demand for high-quality proteins, expansion of academic and research institutes, and advancements in chromatography techniques. These factors have collectively contributed to the advancement and adoption of protein purification and isolation processes.

The protein purification and isolation market size is expected to see rapid growth in the next few years. It will grow to $14.61 billion in 2028 at a compound annual growth rate (CAGR) of 11.1%. The anticipated growth in the forecast period can be attributed to the expanding biologics market, increased funding for life sciences research, a growing demand for personalized medicine, the expansion of contract manufacturing organizations (CMOs), and an increasing need for rapid screening tests. Major trends expected in the forecast period include the adoption of single-use systems in protein purification, the use of high-throughput purification technologies, an emphasis on continuous processing, the integration of automation in protein purification processes, and a focus on sustainable and environmentally friendly practices. These trends reflect the evolving landscape and advancements in protein purification and isolation technologies.

The anticipated increase in government spending on research and development in the pharmaceuticals and biotechnology sectors is poised to drive the growth of the protein purification and isolation market in the foreseeable future. Research and development activities, aimed at acquiring knowledge for product innovation or improvement, play a crucial role in advancing protein purification processes. This increased investment contributes to the development of more sophisticated methods and offers additional benefits such as purified growth factors, hormones, DNA polymerases, and reverse transcriptases. For example, the Indian government allocated USD 10.35 billion, with the Department of Health Research allotting USD 365.68 billion in 2021 for promoting the pharma sector. Similarly, the US Department of Agriculture and National Science spent USD 50 million in 2021 on advancements in alternative protein development. Hence, the rising government expenditure on research and development in pharmaceuticals and biotechnology is a key driver for the protein purification and isolation market.

The growing demand for biopharmaceutical products is expected to be a significant factor propelling the protein purification and isolation market. Biopharmaceuticals, comprising large and complex molecules derived from biological sources, are crucial for therapeutic, diagnostic, and preventive applications. Protein purification and isolation are essential processes in biopharmaceutical production to obtain highly pure and functional proteins, integral for developing drugs like monoclonal antibodies, vaccines, and therapeutic proteins. For instance, the European Federation of Pharmaceutical Industries and Associations reported that the total pharmaceutical production in Europe reached $351 billion in 2021, a 5% increase from $335.2 billion in 2020. This indicates a surging demand for pharmaceutical products, thereby driving the growth of the protein purification and isolation market.

Technological advancements emerge as a notable trend gaining momentum in the protein purification and isolation market. Major companies in the industry are directing their efforts toward developing innovative technologies to gain a competitive edge. In April 2021, Thermo Fisher Scientific launched the KingFisher Apex Purification System, a high-protein sample purification instrument designed for efficient DNA, protein, and cell extraction. This system utilizes automation technology to provide fast, flexible, and error-free sample preparation without additional expenses, capable of processing 24 to 96 samples in 25 to 65 minutes.

Major players in the protein purification and isolation market are introducing innovative products like affinity resin to enhance their product offerings and maintain a competitive advantage. Affinity resin, a specialized type of chromatography matrix, is designed to selectively bind and purify specific target molecules, particularly proteins or biomolecules, from complex mixtures. Navigo Proteins GmbH introduced an innovative affinity resin in June 2022, utilizing Precision Capturing technology to efficiently capture the glycoprotein gp64 contaminant from the baculovirus insect cell expression system. This resin, designed for flow-through chromatography, allows selective binding, ensuring the target recombinant protein can be eluted without interference, effectively removing contaminants from the production process.

In November 2021, Beximco Pharmaceuticals Ltd., a Bangladesh-based pharmaceutical company, acquired Sanofi Bangladesh, a move expected to strengthen Beximco's position in key therapeutic areas, driving sustainable revenue and profit growth. Sanofi, a France-based healthcare company, specializes in protein purification, manufacturing medicines, and vaccine production.

Major companies operating in the in the protein purification and isolation market report are Abcam PLC, Agilent Technologies Inc, Thermo Fisher Scientific Inc., Bio-Rad Laboratories Inc., BioVision Inc., Norgen Biotek Corp., GE Healthcare Technologies Inc., GEA Group AG, Expedeon Ltd., Creative Biostructure, Qiagen NV, Geno Technology Inc., The Merck Group, Labome, Promega Corporation, OPRL Biosciences Pvt. Ltd., Purolite LLC, Takara Bio Inc., F. Hoffmann-La Roche Ltd, Sigma-Aldrich Chemicals Private Limited, Cygnus Technologies LLC, Novasep, Kinnakeet Biotechnology LLC, Cambryn Biologics LLC, Worthington Biochemical Corporation, GenScript Biotech Corporation, Creative BioMart, OriGene Technologies Inc., Proteintech Group Inc., Rockland Immunochemicals Inc., Sino Biological Inc.

North America was the largest region in the protein purification and isolation market in 2023. The regions covered in the protein purification and isolation market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa

The countries covered in the protein purification and isolation market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Italy, Canada, Spain.

The protein purification and isolation market includes revenues earned by entities by isolating one or a few proteins from a complex mixture. The market value includes the value of related goods sold by the service provider or included within the service offering. Only goods and services traded between entities or sold to end consumers are included.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified)).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.


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