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Dravet Syndrome Treatment Market Report and Forecast 2023-2031

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    Report

  • 147 Pages
  • April 2023
  • Region: Global
  • Expert Market Research
  • ID: 5780699
The growth of the global Dravet syndrome treatment size is being driven by the rising prevalence of the condition across the globe. The global Dravet syndrome treatment market is likely to grow at a rate of 10.04% in the forecast period of 2023-2031 to attain a value of USD 0.86 billion by 2031.

Dravet Syndrome Treatment Market: Introduction

Dravet Syndrome, also known as Severe Myoclonic Epilepsy of Infancy (SMEI), is a rare, severe form of epilepsy that starts in infancy. It is a genetic disorder caused by mutations in the SCN1A gene. There is currently no cure for Dravet Syndrome, but there are various treatment options available that aim to manage the symptoms of the disease. The report covers the market for Dravet Syndrome treatment, including drugs and therapies, and provides a detailed analysis of the market size, growth, and trends.

Dravet Syndrome Epidemiology

Dravet Syndrome, also known as Severe Myoclonic Epilepsy of Infancy (SMEI), is a rare genetic disorder that affects approximately one in every 15,700 individuals worldwide. The disease typically begins in infancy, with infants experiencing seizures that are often prolonged and difficult to manage. As the child grows, the seizures may become more frequent and severe, and may be accompanied by cognitive and behavioral problems.

The prevalence of Dravet Syndrome varies by region, but it is estimated to affect approximately one in every 20,000 to 40,000 individuals worldwide. It is more common in males than females, with a male-to-female ratio of approximately 1.5:1.

The treatment options for Dravet Syndrome are focused on managing the symptoms of the disease and improving the quality of life of patients. The primary treatment is medication, specifically anticonvulsants such as clobazam, valproate, and stiripentol. These drugs work by stabilizing the electrical activity in the brain, reducing the frequency and severity of seizures. Benzodiazepines may also be used in combination with anticonvulsants to manage acute seizures.

DRAVET SYNDROME TREATMENT Market Segmentations

The market can be categorised into seizure type, diagnosis type, treatment type, end user, and major region.

Market Breakup by Seizures Type

  • Myoclonic Seizures
  • Atonic Seizures
  • Partial Seizures
  • Absence Seizures
  • Tonic Seizures
  • Photosensitive Seizures
  • Others

Market Breakup by Diagnosis Type

  • Magnetic Resonance Imaging
  • Electroencephalography
  • SCN1 A Testing
  • Others

Market Breakup by Treatment Type

  • Seizure Medications
  • Ketogenic Diet
  • Vagus Nerve Stimulation
  • Others

Market Breakup by End User

  • Pharmaceutical Companies
  • Hospitals
  • Diagnostic Laboratories
  • Academic and Research Institutes
  • Others

Market Breakup by Region

North America

  • United States of America
  • Canada

Europe

  • United Kingdom
  • Germany
  • France
  • Italy
  • Others

Asia Pacific

  • China
  • Japan
  • India
  • ASEAN
  • Australia
  • Others

Latin America

  • Brazil
  • Argentina
  • Mexico
  • Others

Middle East and Africa

  • Saudi Arabia
  • United Arab Emirates
  • Nigeria
  • South Africa
  • Others

Dravet Syndrome Treatment Market Scenario

The global Dravet syndrome treatment market is expected to grow at a significant rate during the forecast period of 2023-2031. The increasing prevalence of the disease, rising awareness, and growing investment in research and development activities are the key drivers of the market. North America dominates the market, followed by Europe and Asia Pacific. The leading players in the market are focusing on the development of new drugs and therapies and adopting various strategies to strengthen their position in the market.

North America dominates the Dravet Syndrome treatment market, followed by Europe and Asia Pacific. The high prevalence of Dravet Syndrome in North America, coupled with the favorable reimbursement policies, is driving the growth of the market in the region. Europe is also a significant market for Dravet Syndrome treatment, with the presence of key players and increasing investment in research and development activities. The Asia Pacific region is expected to grow at the highest CAGR during the forecast period, owing to the increasing awareness about the disease and the rising healthcare expenditure in the region.

Key Players in the Global Dravet Syndrome Treatment Market

The report gives an in-depth analysis of the key players involved in the Dravet Syndrome Treatment market, sponsors manufacturing the drugs, and putting them through trials to get FDA approvals. The companies included in the market are as follows:
  • Biocodex
  • Biscayne Neurotherapeutics (Supernus Pharmaceuticals, Inc)
  • Cyberonics (LivaNova PLC)
  • Epygenix Therapeutics, Inc
  • GW Pharmaceuticals (Jazz Pharmaceuticals, Inc)
  • OPKO Health, Inc
  • Ovid Therapeutics
  • PTC Therapeutics
  • Encoded Therapeutics, Inc
  • Zogenix (UCB S.A, Belgium)
  • Takeda Pharmaceutical Company Limited

Table of Contents

1 Preface
1.1 Objectives of the Study
1.2 Key Assumptions
1.3 Report Coverage - Key Segmentation and Scope
2 Research Methodology3 Executive Summary
4 Global Dravet Syndrome Overview
4.1 Guidelines and Stages
4.2 Pathophysiology
4.3 Screening and Diagnosis
4.4 Treatment Pathway
5 Patient Profile
5.1 Patient Profile Overview
5.2 Patient Psychology and Emotional Impact Factors
5.3 Risk Assessment and Treatment Success Rate
6 Current Scenario Evaluation and Regulatory Framework
6.1 Emerging Therapies and Clinical Trials
6.2 Patent Landscape
6.2.1 Patent Overview
6.2.1.1 Patent Status and Expiry
6.2.1.2 Timelines from Drug Development to Commercial Launch
6.2.1.3 New Drug Application
6.2.1.3.1 Documentation and Approval Process
6.3 Cost of Treatment
6.4 Regulatory Framework
6.4.1 Regulatory Overview
6.4.1.1 US FDA
6.4.1.2 EU EMA
6.4.1.3 INDIA CDSCO
6.4.1.4 JAPAN PMDA
6.4.1.5 Others
7 Challenges and Unmet Needs
7.1 Treatment Pathway Challenges
7.2 Compliance and Drop-Out Analysis
7.3 Awareness and Prevention Gaps
8 Global Dravet Syndrome Treatment Market
8.1 Global Dravet Syndrome Treatment Market Overview
8.2 Global Dravet Syndrome Treatment Market Analysis
8.2.1 Market Overview
8.2.1.1 Global Dravet Syndrome Treatment Market Historical Value (2016-2022)
8.2.1.2 Global Dravet Syndrome Treatment Market Forecast Value (2023-2031)
8.2.2 Global Dravet Syndrome Treatment Market by Seizures Type
8.2.2.1 Market Overview
8.2.2.1.1 Myoclonic Seizures
8.2.2.1.2 Atonic Seizures
8.2.2.1.3 Partial Seizures
8.2.2.1.4 Absence Seizures
8.2.2.1.5 Tonic Seizures
8.2.2.1.6 Photosensitive Seizures
8.2.2.1.7 Others
8.2.3 Global Dravet Syndrome Treatment Market by Diagnosis Type
8.2.3.1 Market Overview
8.2.3.1.1 Magnetic Resonance Imaging
8.2.3.1.2 Electroencephalography
8.2.3.1.3 Scn1 A Testing
8.2.3.1.4 Others
8.2.4 Global Dravet Syndrome Treatment Market by Treatment Type
8.2.4.1 Market Overview
8.2.4.1.1 Seizure Medications
8.2.4.1.2 Ketogenic Diet
8.2.4.1.3 Vagus Nerve Stimulation
8.2.4.1.4 Others
8.2.5 Global Dravet Syndrome Treatment Market by End User
8.2.5.1 Market Overview
8.2.5.1.1 Pharmaceutical Companies
8.2.5.1.2 Hospitals
8.2.5.1.3 Diagnostic Laboratories
8.2.5.1.4 Academic and Research Institutes
8.2.5.1.5 Others
8.2.6 Global Dravet Syndrome Treatment Market by Region
8.2.6.1 Market Overview
8.2.6.1.1 North America
8.2.6.1.2 Europe
8.2.6.1.3 Asia Pacific
8.2.6.1.4 Middle East and Africa
8.2.6.1.5 Latin America
9 North America Dravet Syndrome Treatment Market
9.1 Market Share by Country
9.2 United States of America
9.2.1 Historical Trend (2016-2022)
9.2.2 Forecast Trend (2023-2031)
9.3 Canada
9.3.1 Historical Trend (2016-2022)
9.3.2 Forecast Trend (2023-2031)
10 Europe Dravet Syndrome Treatment Market
10.1 Market Share by Country
10.2 United Kingdom
10.2.1 Historical Trend (2016-2022)
10.2.2 Forecast Trend (2023-2031)
10.3 Germany
10.3.1 Historical Trend (2016-2022)
10.3.2 Forecast Trend (2023-2031)
10.4 France
10.4.1 Historical Trend (2016-2022)
10.4.2 Forecast Trend (2023-2031)
10.5 Italy
10.5.1 Historical Trend (2016-2022)
10.5.2 Forecast Trend (2023-2031)
10.6 Others
11 Asia Pacific Dravet Syndrome Treatment Market
11.1 Market Share by Country
11.2 China
11.2.1 Historical Trend (2016-2022)
11.2.2 Forecast Trend (2023-2031)
11.3 Japan
11.3.1 Historical Trend (2016-2022)
11.3.2 Forecast Trend (2023-2031)
11.4 India
11.4.1 Historical Trend (2016-2022)
11.4.2 Forecast Trend (2023-2031)
11.5 ASEAN
11.5.1 Historical Trend (2016-2022)
11.5.2 Forecast Trend (2023-2031)
11.6 Australia
11.6.1 Historical Trend (2016-2022)
11.6.2 Forecast Trend (2023-2031)
11.7 Others
12 Latin America Dravet Syndrome Treatment Market
12.1 Market Share by Country
12.2 Brazil
12.2.1 Historical Trend (2016-2022)
12.2.2 Forecast Trend (2023-2031)
12.3 Argentina
12.3.1 Historical Trend (2016-2022)
12.3.2 Forecast Trend (2023-2031)
12.4 Mexico
12.4.1 Historical Trend (2016-2022)
12.4.2 Forecast Trend (2023-2031)
12.5 Others
13 Middle East and Africa Dravet Syndrome Treatment Market
13.1 Market Share by Country
13.2 Saudi Arabia
13.2.1 Historical Trend (2016-2022)
13.2.2 Forecast Trend (2023-2031)
13.3 United Arab Emirates
13.3.1 Historical Trend (2016-2022)
13.3.2 Forecast Trend (2023-2031)
13.4 Nigeria
13.4.1 Historical Trend (2016-2022)
13.4.2 Forecast Trend (2023-2031)
13.5 South Africa
13.5.1 Historical Trend (2016-2022)
13.5.2 Forecast Trend (2023-2031)
13.6 Others
14 Global Dravet Syndrome Treatment Market Dynamics
14.1 Market Drivers and Constraints
14.2 SWOT Analysis
14.3 Porter’s Five Forces Model
14.4 Key Demand Indicators
14.5 Key Price Indicators
14.6 Industry Events, Initiatives, and Trends
14.7 Value Chain Analysis
15 Supplier Landscape
15.1 Biocodex
15.1.1 Company Overview
15.1.2 Product Portfolio
15.1.3 Demographic Reach and Achievements
15.1.4 Mergers and Acquisitions
15.1.5 Certifications
15.2 Biscayne Neurotherapeutics (Supernus Pharmaceuticals, Inc.)
15.2.1 Company Overview
15.2.2 Product Portfolio
15.2.3 Demographic Reach and Achievements
15.2.4 Mergers and Acquisitions
15.2.5 Certifications
15.3 Cyberonics (LivaNova PLC)
15.3.1 Company Overview
15.3.2 Product Portfolio
15.3.3 Demographic Reach and Achievements
15.3.4 Mergers and Acquisitions
15.3.5 Certifications
15.4 Epygenix Therapeutics, Inc.
15.4.1 Company Overview
15.4.2 Product Portfolio
15.4.3 Demographic Reach and Achievements
15.4.4 Mergers and Acquisitions
15.4.5 Certifications
15.5 GW Pharmaceuticals (Jazz Pharmaceuticals, Inc.)
15.5.1 Company Overview
15.5.2 Product Portfolio
15.5.3 Demographic Reach and Achievements
15.5.4 Mergers and Acquisitions
15.5.5 Certifications
15.6 OPKO Health, Inc.
15.6.1 Company Overview
15.6.2 Product Portfolio
15.6.3 Demographic Reach and Achievements
15.6.4 Mergers and Acquisitions
15.6.5 Certifications
15.7 Ovid Therapeutics
15.7.1 Company Overview
15.7.2 Product Portfolio
15.7.3 Demographic Reach and Achievements
15.7.4 Mergers and Acquisitions
15.7.5 Certifications
15.8 PTC Therapeutics
15.8.1 Company Overview
15.8.2 Product Portfolio
15.8.3 Demographic Reach and Achievements
15.8.4 Mergers and Acquisitions
15.8.5 Certifications
15.9 Encoded Therapeutics, Inc.
15.9.1 Company Overview
15.9.2 Product Portfolio
15.9.3 Demographic Reach and Achievements
15.9.4 Mergers and Acquisitions
15.9.5 Certifications
15.10 Zogenix (UCB S.A., Belgium)
15.10.1 Company Overview
15.10.2 Product Portfolio
15.10.3 Demographic Reach and Achievements
15.10.4 Mergers and Acquisitions
15.10.5 Certifications
15.11 Takeda Pharmaceutical Company Limited
15.11.1 Company Overview
15.11.2 Product Portfolio
15.11.3 Demographic Reach and Achievements
15.11.4 Mergers and Acquisitions
15.11.5 Certifications
16 Global Dravet Syndrome Treatment Market Distribution Model (Additional Insight)
16.1 Overview
16.2 Potential Distributors
16.3 Key Parameters for Distribution Partner Assessment
17 Payment Methods (Additional Insight)
17.1 Government Funded
17.2 Private Insurance
17.3 Out-of-Pocket

Companies Mentioned

  • Biocodex
  • Biscayne Neurotherapeutics (Supernus Pharmaceuticals, Inc.)
  • Cyberonics (LivaNova PLC)
  • Epygenix Therapeutics, Inc.
  • GW Pharmaceuticals (Jazz Pharmaceuticals, Inc.)
  • OPKO Health, Inc.
  • Ovid Therapeutics
  • PTC Therapeutics
  • Encoded Therapeutics, Inc.
  • Zogenix (UCB S.A., Belgium)
  • Takeda Pharmaceutical Company Limited

Methodology

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Table Information