Structural Biology and Molecular Modeling Techniques Global Market Report 2024

The global structural biology and molecular modeling techniques market has grown rapidly in recent years. It will grow from $7.58 billion in 2023 to $9.00 billion in 2024 at a compound annual growth rate (CAGR) of 18.7%. The growth observed during the historical period can be linked to several factors, including the emergence of cryo-electron microscopy, advancements in pharmaceutical research and drug discovery, enhanced understanding of enzyme mechanisms, the expansion of structural genomics initiatives, validation of drug targets, insights obtained from structural analyses of viral proteins, and studies focused on drug resistance.

The global structural biology and molecular modeling techniques market is expected to see rapid growth in the next few years. It will grow to $17.39 billion in 2028 at a compound annual growth rate (CAGR) of 17.9%. Anticipated growth in the forecast period can be credited to various factors, including the expansion of fragment-based drug design, advancements in hybrid methods, rapid progress in structural proteomics, the integration of precision medicine applications in oncology, increased utilization of structural biology in neuroscience research, expanding applications in RNA biology, and the evolution of structural bioinformatics. Key trends expected in the forecast period encompass the integration of artificial intelligence (AI) methodologies, the utilization of hybrid methods for structural determination, the increased use of single-particle analysis in cryo-electron microscopy (cryo-EM), advancements in elucidating membrane protein structures, the development of open-source software, the utilization of NMR spectroscopy, the integration of structural biology in personalized medicine, and technological enhancements in X-ray crystallography methodologies.

The escalating prevalence of chronic diseases is anticipated to drive the growth of the structural biology and molecular modeling techniques market. Chronic diseases, lasting for three months or longer and often worsening over time, include prominent conditions like cancer, heart disease, stroke, diabetes, and arthritis. Structural biology is instrumental in investigating the origins of such illnesses, with structure-guided approaches proving valuable in various aspects of early drug discovery, both computationally and empirically. This includes understanding the effects of genetic mutations leading to human diseases and addressing treatment resistance in conditions like cancer and infectious diseases. As of January 2023, the National Center for Biotechnology Information (NCBI) predicts a global increase in the number of people with chronic diseases, reaching 142.66 million by 2050, up from 71.522 million in 2020. This substantial rise in chronic diseases is a key driver propelling the structural biology and molecular modeling techniques market.

The growing adoption of personalized medicine is expected to further propel the growth of the structural biology and molecular modeling techniques market. Personalized medicine, tailoring medical treatment to individual patient characteristics, relies on structural biology and molecular modeling techniques for identifying and validating molecular targets, supporting drug discovery and development, understanding genetic variations, predicting drug-target interactions, optimizing drug delivery, and contributing to biomarker discovery. In 2022, the Food and Drug Administration's Center for Drug Evaluation and Research (CDER) approved 37 new molecular entities (NMEs), and approximately 34% of therapeutic NMEs (12 out of 35) were classified as personalized medicines by the Personalized Medicine Coalition (PMC). This increasing adoption of personalized medicine reflects a growing reliance on structural biology and molecular modeling techniques, driving market growth.

A key trend gaining popularity in the structural biology and molecular modeling techniques market is technological advancements. Major companies in the market are actively developing innovative technologies, including next-generation sequencing-based ctDNA Testing, in silico screening of 3-D chemical structures, and advanced software, to maintain their competitive edge. In March 2022, PerkinElmer Inc., a US-based provider of products, solutions, and services to the applied services, life sciences, and diagnostics markets, introduced ChemDraw V21 software. This software facilitates the quick native import, animation, and sharing of 3D chemical structures in Microsoft PowerPoint, allowing chemists to generate more insightful research reports efficiently. The continuous development of cutting-edge technologies is a key trend shaping the structural biology and molecular modeling techniques market.

Major players in the structural biology and molecular modeling techniques market are actively developing new AI foundation models to gain a competitive edge. In March 2023, Nvidia Corporation, a US-based software company, launched BioNeMo Cloud, a set of generative AI cloud services as part of NVIDIA AI Foundations. This service is designed to accelerate life sciences research, drug discovery, and protein engineering by providing pretrained AI models and allowing researchers to customize them with proprietary data. Among the six new optimized, open-source models included in this service are AlphaFold2 for protein structure determination and MoFlow for molecular optimization and small molecule generation. This initiative by Nvidia Corporation exemplifies the industry's commitment to leveraging AI technologies for advancing structural biology and molecular modeling techniques.

In September 2022, Cadence Design Systems Inc., a US-based computational software company, made a strategic move by acquiring OpenEye Scientific Software, Inc. for an undisclosed amount. This acquisition significantly bolstered Cadence's Intelligent System Design strategy by incorporating OpenEye's technologies and experienced team. It extended Cadence's core competency in computational software to molecular modeling specifically targeted at life sciences. OpenEye Scientific Software Inc., the acquired company, is recognized for its expertise in computational molecular design, aligning with Cadence's focus on advancing computational tools for molecular modeling in the life sciences sector. This acquisition reflects the industry's recognition of the importance of molecular modeling and computational tools, driving companies to enhance their capabilities through strategic acquisitions and partnerships.

Major companies operating in the structural biology and molecular modeling techniques market report are Thermo Fisher Scientific Inc., Agilent Technologies Inc., Agile Molecule Inc., Bruker Corporation, Dassault Systèmes SE, Illumina Inc., Chemical Computing Group ULC, Biomax Informatics AG, Affymetrix Inc., Horiba Ltd., Charles River Laboratories Inc., Adjuvance Technologies Inc., Novartis AG, QIAGEN N.V., Avanti Polar Lipids Inc., Acellera Ltd., Schrödinger Inc., OpenEye Scientific Software Inc., BioSolveIT GmbH, Optibrium Ltd., Simulations Plus Inc., Certara L.P., Genedata AG, Inte:Ligand GmbH, Molecular Networks GmbH, Molecular Discovery Ltd., Cresset Group Ltd., Biotherapeutics Inc., Biovista Inc., Collaborative Drug Discovery Inc., Dotmatics Ltd., Insilico Biotechnology AG, Leadscope Inc.

North America was the largest region in the structural biology and molecular modelling techniques market in 2023. The regions covered in the structural biology and molecular modeling techniques market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa. The countries covered in the structural biology and molecular modeling techniques market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

The primary tools employed in structural biology and molecular modeling encompass Software as a Service (SaaS) and standalone modeling software, visualization and analysis tools, databases, and other specialized utilities. SaaS operates through a cloud-based framework, hosted by a provider and accessible to end-users online, while standalone software requires installation and maintenance on the user's computer, necessitating the user's management of the program and hardware, unless covered by provided software maintenance and support. SaaS and standalone modeling tools serve specific functions within predefined parameters. These techniques find extensive application in various domains such as drug development, drug discovery, and other pharmaceutical, biotechnological, academic, and clinical trial endeavors.

This report provides structural biology and molecular modelling techniques market statistics, including structural biology and molecular modelling techniques industry global market size, regional shares, competitors with a structural biology and molecular modelling techniques market share, detailed structural biology and molecular modelling techniques market segments, structural biology and molecular modeling techniques market trends and opportunities, and any further data you may need to thrive in the structural biology and molecular modelling techniques industry. This structural biology and molecular modelling techniques market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.

The structural biology and molecular modeling techniques market includes revenues earned by entities by using techniques such as homology modeling, threading, molecular dynamics cryo-electron microscopy (cryo-EM), nuclear magnetic resonance spectroscopy of proteins (NMR), and electron paramagnetic resonance (EPR). The market value includes the value of related goods sold by the service provider or included within the service offering. Only goods and services traded between entities or sold to end consumers are included.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.


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