Cell Expansion Market Report 2025

The cell expansion market size has grown rapidly in recent years. It will grow from $28.11 billion in 2024 to $32.22 billion in 2025 at a compound annual growth rate (CAGR) of 14.6%. The growth in the historic period can be attributed to public awareness and acceptance, cell-based research applications, rising demand for cell-based therapies, biopharmaceutical industry growth, regenerative medicine advancements.

The cell expansion market size is expected to see rapid growth in the next few years. It will grow to $59.14 billion in 2029 at a compound annual growth rate (CAGR) of 16.4%. The growth in the forecast period can be attributed to rising investments in biotechnology, expanding stem cell research, clinical trials and drug development, demand for personalized medicine, biobanking and cell repositories. Major trends in the forecast period include technological advancements, product innovations, strategic collaborations.

The rising prevalence of chronic diseases is anticipated to drive the demand for the cell expansion market in the future. Chronic diseases are long-lasting conditions that often cannot be cured, although they can sometimes be managed or controlled. Their increasing prevalence is attributed to factors such as tobacco use, poor nutrition, physical inactivity, and excessive alcohol consumption. Cell expansion plays a crucial role in replenishing nutrients and preventing the buildup of toxic metabolic waste products that could hinder culture performance. For instance, in January 2023, the National Center for Biotechnology Information (NCBI), part of the US National Library of Medicine, projected that by 2050, the number of individuals aged 50 and older with at least one chronic illness will rise by 99.5%, increasing from 71.522 million in 2020 to 142.66 million. Consequently, the growing incidence of chronic diseases is expected to boost the growth of the cell expansion market.

The growth of the cell expansion market is expected to be propelled by increasing government funding for research and development. Government funding plays a crucial role in fostering innovation, advancing cell-based therapies, and accelerating progress in regenerative medicine. An illustrative example is the National Cancer Institute, a US-based government agency, which received a budget of $7.3 billion in fiscal year 2023 from the United States Congress, marking a $408 million increase from 2022. This substantial increase in government funding for research and development is a driving force behind the growth of the cell expansion market.

Leading companies in the cell expansion market are focusing on advancements in bioprocessing technologies, such as automated 3D bioreactor systems, to improve the efficiency and scalability of cell production for therapeutic purposes. PluriCDMO specializes in large-scale, automated manufacturing of cell therapies utilizing a proprietary 3D bioreactor system, ensuring consistent, high-quality production from early development to clinical trials. For example, in January 2024, Pluristem Therapeutics Inc., a biotechnology company based in Israel, launched a new division called PluriCDMO that will provide cell therapy manufacturing services as a contract development and manufacturing organization (CDMO). This new division features a 47,000-square-foot good manufacturing practice (GMP) facility dedicated to cell therapy production. Through PluriCDMO, the company will offer services ranging from early preclinical development to late-stage clinical trials and commercialization.

Major companies in the cell expansion market are intensifying their focus on introducing advanced bioprocessing platforms, such as the Quantum Flex Cell Expansion System, to gain a competitive edge. The Quantum Flex Cell Expansion System, launched by Terumo Blood and Cell Technologies in June 2023, is designed for scalable and flexible expansion of cell therapies, providing efficient and controlled manufacturing capabilities for cell-based medical treatments. This system supports the expansion of various applications, including suspension and adherent cells, viral vectors, and exosome production, offering the necessary flexibility, scalability, and connectivity to support the growth of cell therapies.

In a strategic move, Sartorius AG, a Germany-based pharmaceutical company, acquired Polyplus-Transfection SA for $2.36 billion in March 2023. This acquisition positions Sartorius AG to strengthen its supply of cell and gene therapy solutions, expanding its portfolio for gene therapies and gene-modified cell therapies. Polyplus-Transfection SA, based in France, is a biotechnology company supporting gene and cell therapy, biologics manufacturing, and life science research.

Major companies operating in the cell expansion market are Thermo Fisher Scientific Inc., Becton Dickinson and Company, Lonza Group, Corning Inc., Merck KGaA, Sartorius Stedim Biotech SA, Terumo Corporation, Miltenyi Biotec GmbH, Danaher Corporation, Stemcell Technologies Inc., Beckman Coulter Inc., Takara Bio Inc., RepliCel Life Sciences, Neximmune Inc., Celltainer Biotech BV, GE HealthCare Technologies Inc., ReproCELL USA Inc., iXCells Biotechnologies Inc., Neuromics LLC, G&G Technologies Inc., Eppendorf AG, Avantor Inc., Bio-Techne Corporation, BioLife Solutions Inc., Cesca Therapeutics Inc., Core Dynamics Ltd., Lifeline Scientific Inc., Princeton Cryotech Inc., VWR International LLC, Azenta US Inc., MVE Biological Solutions LLC, BioCision LLC, BioSpherix Ltd., Worthington Industries Inc.

North America was the largest region in the cell expansion market share in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the cell expansion market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa. The countries covered in the cell expansion market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

Cell expansion is a cellular process employed to generate new cell wall material, with the primary objective of regulating the flexibility of the wall and facilitating its stretching and expansion in a specific area. Essential to this process are cell-wall-associated proteins belonging to the expansion family.

The main categories of cell expansion include mammalian, microbial, and other types. Mammalian cell expansion involves the cultivation of cells derived from mammals, conducted through the in vitro cultivation of cells in flasks or bioreactors. The products associated with mammalian cell expansion encompass consumables, reagents, media, serums, disposables, and instruments. These products find application in various fields such as biopharmaceuticals, tissue culture and engineering, vaccine production, drug development, gene therapy, cancer research, stem cell research, and others. The end-users of mammalian cell expansion products include biopharmaceutical and biotechnology companies, research institutes, cell banks, and other relevant entities.

The cell expansion market research report is one of a series of new reports that provides cell expansion market statistics, including cell expansion industry global market size, regional shares, competitors with a cell expansion market share, detailed cell expansion market segments, market trends and opportunities, and any further data you may need to thrive in the cell expansion industry. This cell expansion market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.

The cell expansion market includes revenues earned by entities by providing bioreactors and automated cell expansion systems. The market value includes the value of related goods sold by the service provider or included within the service offering. Only goods and services traded between entities or sold to end consumers are included.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

This product will be delivered within 3-5 business days.