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Microbes, Microbial Metabolism and Mucosal Immunity. An Overview

  • Book

  • August 2024
  • Elsevier Science and Technology
  • ID: 5789714

Microbes, Microbial Metabolism and Mucosal Immunity: An Overview presents a concise and well-vetted treatise on the study of microbiome and microbial metabolites. This volume is up-to-date with the most recent developments from the last decade. It encompasses the interaction of immunity and microbes - and their metabolites - from different mucosal organs including gastrointestinal system, lung, oral cavity, eye. Along with the efficiency of the immune system in inhibiting the growth and proliferation of microbes, the volume discusses how the mediators of the immune system can be targeted to develop therapies.

This book presents the latest methods, gives broad and systematic coverage of most mucosal systems and diseases, and takes a fresh perspective that looks at the functional aspects of change in the microbiome. The study of microbiome and microbial metabolites and their roles in host mucosal immunology is a rapidly developing area of research. One major way in which the microbiome influences the host is through altered metabolism. Metabolites, readily available to the host, engender significant consequences. Microbial metabolites have been shown to impact the disease processes in both proximal and distal organs, including the brain in several neurocognitive disorders.

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Table of Contents

1. Intestinal barrier immunity: key players in the gut microbial “meet and greet or get-rid” event
2. Gut-brain communication through microbes
3. Role of gut microbes in shaping neonatal immunity and beyond
4. Respiratory microbiome
5. Oral immune system and microbes
6. The eye and the microbiome
7. Commensal virome and mycobiome
8. Microbiome and the COVID-19 pandemic

Authors

Tanima Bose Institute of Clinical Neuroimmunology, University of Munich (LMU), Gro�haderner Stra�e 9, 82152 Munich, Germany. Dr. Tanima Bose, Institute for Clinical Neuroimmunology, University of Munich, Germany

Tanima Bose has been working in the field of immunology for almost 15+ years. After finishing her PhD in the interaction of ion channels in immune cells from Leibniz Institute for Neuroimmunology in collaboration with the Clinical Immunology Department in Magdeburg, Germany, she expanded her research internationally in Singapore, USA, Australia before returning to the University of Munich, Germany. Her research focuses on the tissue-resident and memory immune cells, and their role in autoimmune, allergic, and neuroimmunological disease. She is finishing her habilitation and will continue teaching in the field of mucosal immunology. She hopes that Pharma companies will be encouraged by her translational research.

Along with her academic work, Tanima Bose is very active in editing, writing, and public speaking. She has written numerous research papers (20+), book chapters (5+), protocols, and blogs and has been part of the editorial team of several journals (10+). In her free time, she likes to inspire women more in scientific activities; one example is her participation in Soapbox Science (https://munichsoapboxscience.com/soapbox-science-2020/10/).