Synthetic Polymers in Drug and Biotherapeutics Delivery covers new polymers that are fast replacing obsolete polymers in the field of drug delivery. Each chapter focuses on a specific polymer, detailing its design, synthesis, fabrication techniques, and applications in drug and biotherapeutics delivery. Synthetic polymers provide a unique set of opportunities in drug and biotherapeutics delivery due to their chemical versatility and tunable physicochemical properties. Such polymers can be formulated into nanoparticles, nanofibers, nanogels, microparticles, beads, hydrogels, and scaffolds to suit specific needs such as drug release rate, and biodegradation with low toxicity. This book covers new polymers that are fast replacing obsolete polymers in the field of drug delivery. Each chapter will focus on a specific polymer detailing its design, synthesis, fabrication techniques, and applications in drug and biotherapeutics delivery. This book provides a thorough review of the latest research in this rapidly changing field and would be of interest to materials scientists, pharmaceutical scientists, biomedical engineers, chemical engineers, and clinicians with an interest in materials development.
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Table of Contents
1. Role and challenges of synthetic biopolymers in drug/ biotherapeutic delivery 2. Poly(caprolactone) 3. Poly(lactic-co-glycolic acid) in drug delivery and tissue engineering applications 4. Poly(amidoamine)-based dendrimers for biomedical applications 5. pH-responsive synthetic polymers for drug delivery applications 6. Chemistry, properties, and role of polyoxazoline in drug delivery 7. Poly(amides) 8. Polyethyleneimine-based biomaterials for therapy and diagnostic applications 9. Polyethylene glycol: structure, properties, and biomedical applications 10. Poly(N-isopropyl acrylamide): a thermo-responsive polymer for bio-therapeutic applications 11. Poly(2-hydroxyethyl methacrylate): a new leap to accelerate the effective biotherapeutic and drug delivery systems 12. Poly(N-(2-hydroxypropyl)methacrylamide) 13. Polydioxanone in drug delivery 14. Poly(lactide) 15. Blending techniques and formulation strategies 16. Clinical application, regulatory status, and future perspective of synthetic biopolymers in drug/bio-therapeutics delivery
Authors
Rangasamy Jayakumar Professor, Centre for Nanosciences and Molecular Medicine, Amrita Vishwa Vidyapeetham (Deemed University), Kerala, India.Rangasamy Jayakumar is a Professor at the Centre for Nanosciences and Molecular Medicine, Amrita Vishwa Vidyapeetham (Deemed University), Kerala, India. He received his PhD degree in polymer chemistry from Anna University, Chennai, India (2002) and MSc degree from Bharathidasan University.
Mar Masson Professor, Faculty Pharmaceutical Sciences, University of Iceland, Reykjav�k, Iceland.M�r M�sson is a Professor of medicinal chemistry at the Faculty of Pharmaceutical Sciences in the University of Iceland. He graduated as a Doctor of Engineering (biotechnology) from Tokyo Institute of Technology, Japan, in 1995 and with a Cand. Scient (MS) in organic chemistry from Copenhagen University, Denmark, in 1990.
Deepagan Veerasikku Gopal Research Fellow (Post-doc), Monash Institute of Pharmaceutical Sciences, Australia.Deepagan Veerasikku Gopal is a Research Fellow at Monash Institute of Pharmaceutical Sciences, Australia, since March 2018. He completed his PhD in polymer science and engineering at Sungkyunkwan University, Republic of Korea, and Masters in nanomedicine at Amrita University, India.
