Ion-Exchange Chromatography and Related Techniques defines the current state-of-the-art in ion-exchange chromatography and related techniques and their implementation in laboratory and industrial practice. This book provides a compact source of information to facilitate the transfer of knowledge and experience acquired by separation science specialists to colleagues from diverse backgrounds who need to acquire fundamental and practical information to facilitate progress in research and management functions reliant on information acquired by separation. Individual chapters written by recognized experts lending credibility to the work will allow this book to serve as a high value reference source of current information for analytical and biopharmaceutical chemists.
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Table of Contents
1. Core concepts and milestones in the development of ion-exchange separations2. Theoretical considerations for the separation of ions3. Ion-exchange equilibria and kinetics of biopolymers4. Stationary phases for ion separations by ion-exchange chromatography5. Stationary phases for the separation of biopolymers by ion-exchange chromatography6. Ion-exchange separations on grafted and surface-modified polymers7. Liquid ion-exchangers8. Ion-exchange membranes9. Ion-exclusion chromatography10. Ion-chelation chromatography11. Displacement chromatography with ion exchangers12. Instrument platforms for ion chromatography13. Ion detection14. Instrument platforms for large-scale ion-exchange separations15. Method development for ion-exchange chromatography16. Sample preparation for ion-exchange separations17. Separation of ions by ion chromatography18. Applications of ion chromatography in environmental analysis19. Applications of ion-exchange chromatography in the food industry20. Applications of ion-exchange chromatography in hydrometallurgy21. Separation of saccharides by ion-exchange chromatography22. Separation of oligonucleotides by ion-exchange chromatography23. Separation of amino acids, peptides, and proteins by ion-exchange chromatography24. Separation of proteins by mixed-mode chromatography25. Process modeling of protein separations by ion-exchange chromatography26. Applications of Ion-exchange chromatography for the purification of antibodies27. Continuous chromatography for protein polishing and enrichment using ion exchange28. Separation of bio-particles by ion-exchange chromatography29. Separation of isotopes by ion-exchange and ion-chelation chromatography
Authors
Pavel Nesterenko Leading Researcher, Moscow State University, Russia, Laboratory of Adsorption and Gas Chromatography, Chemistry Department Lomonosov Moscow State University, Moscow, Russia.
Prof. Pavel Nesterenko holds a position of Leading Researcher in the Laboratory of Adsorption and Gas Chromatography at the Department of Chemistry M.V. Lomonosov Moscow State University. Received MSc (1979) in petroleum chemistry and organic catalysis, PhD (1984) and DSc degrees (2000) in analytical chemistry from M.V. Lomonosov Moscow State University (Moscow, Russia). Senior Researcher (1988), Leading Researcher (2001) and Professor of Analytical Chemistry (2003). In 2006-2018 was awarded Quantum Leap Professor and New Star Professor positions at Australian Centre for Research on Separation Science (ACROSS) and worked at the University of Tasmania, Hobart, Australia. Author of more than 380 scientific publications including 4 books, 14 Chapters in books, 350 regular papers and 13 patents. Research interests are associated with development and investigation of new advanced materials with focus on their selectivity and efficiency for various separation and detection technologies.
Colin Poole Department of Chemistry, Wayne State University, Detroit, MI, USA.
Professor Colin Poole is internationally known in the field of thin-layer chromatography and is an editor of the Journal of Chromatography and former editor of the Journal of Planar Chromatography - Modern TLC. He has authored several books on chromatography, recent examples being The Essence of Chromatography published by Elsevier (2003), and Gas Chromatography published by Elsevier (2012). He is the author of approximately 400 research articles, many of which deal with thin-layer chromatography, and is co-chair of the biennial "International Symposium on High-Performance Thin-Layer Chromatography�.
Yan Sun Chair Professor and Cheung Kong Professor, Biochemical Engineering, Tianjin University, Tianjin, China.
Professor Yan Sun received Doctor of Engineering Degree in the University of Tokyo in 1990. He started his teaching and research career in Tianjin University (TJU) in 1991 and became a full Professor in 1993. He is now a Chair Professor of TJU. In 2000, he was appointed to the Cheung Kong Professorship by the Ministry of Education (MOE) of China. In 2011, he received the Young Asian Biochemical Engineers' Community Award from the Asian Federation of Biotechnology, and during 2002 to 2012 he received three academic research awards on bioseparations in China. His research interests include bioseparations and biocatalysis. He is an Editor of the Journal Chromatography A, an Associate Editor of Biochemical Engineering Journal, and an Associate Editor of Chinese Journal of Chemical Engineering. His work has produced over 400 research papers published in peer-reviewed international journals and one book (Bioseparations Engineering, in Chinese).