Pharmacogenomics: From Discovery to Clinical Implementation is a complete reference aimed at building a solid foundation of the key concepts in this fast-moving knowledge area. The book's chapters over the foundational aspects of pharmacogenomics, including drug metabolism, drug discovery, development, and testing, and then detail studies of key health conditions and the potential therapeutic applications of pharmacogenomics. Diseases covered include diabetes, cardiovascular diseases, psychiatric disease, cancer, pulmonary and respiratory diseases, viral diseases, gastroenterology, autoimmune diseases, immunosuppressants, and, finally, an overview of computational resources. This is the perfect resource for pharmaceutical science graduate students to learn the key concepts of the area. However, researchers and graduate students in the related fields of genetics, pharmacoepidemiology, molecular biology, and medicinal chemistry will also benefit from the structured approach of the book.
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Table of Contents
Part I: Fundamentals
1. Basics of Pharmacogenomics
2. Pharmacogenomics in Drug metabolism
3. Pharmacogenomics in Drug discovery and development
4. Pharmacogenetic Testing
Part II: Therapeutics
5. Pharmacogenomics and Diabetes
6. Pharmacogenomics in Cardiovascular diseases
7. Pharmacogenomics in Psychiatric diseases
8. Pharmacogenomics in Cancer
9. Pharmacogenomics of Pulmonary and Respiratory diseases
10. Pharmacogenomics in Viral Diseases
11. Pharmacogenomics in Gastroenterology
12. Pharmacogenomics in autoimmune diseases
13. Pharmacogenomics of Immunosuppressants
14. Computational and Pharmacogenomic Resources