Cryostat Market Report 2025

The cryostat market size has grown strongly in recent years. It will grow from $2.56 billion in 2024 to $2.7 billion in 2025 at a compound annual growth rate (CAGR) of 5.5%. The growth in the historic period can be attributed to expansion of biomedical research, rise of cryo-electron microscopy (cryo-EM), biobanking and biorepository development, cancer research and diagnostics, drug discovery and development, tissue engineering advancements, increase in cryonics services.

The cryostat market size is expected to see strong growth in the next few years. It will grow to $3.66 billion in 2029 at a compound annual growth rate (CAGR) of 7.9%. The growth in the forecast period can be attributed to expanding role in drug manufacturing, growing importance of genomic research, global expansion of biobanking activities, quality control in pharmaceuticals, shift towards point-of-care diagnostics, advancements in cryogenic storage systems. Major trends in the forecast period include advancements in cryogenic technologies, technological innovations in imaging, integration with artificial intelligence, collaborations for research and development, applications in nanotechnology.

The increasing prevalence of neuromuscular diseases is projected to drive growth in the cryostat market in the future. Neuromuscular diseases encompass conditions that affect the peripheral nervous system, often leading to progressive muscle weakness as a significant symptom. Cryostats play a crucial role in providing rapid diagnoses for various illnesses, including neuromuscular disorders, thus elevating the demand for cryostats in response to the rising incidence of these diseases. For instance, in December 2022, Osteopaths For Industry Ltd., a UK-based company focused on musculoskeletal injury prevention training and consultancy, reported 477,000 cases of work-related musculoskeletal disorders for the 2021-2022 period. Moreover, in July 2022, the World Health Organization indicated that approximately 1.71 billion people globally suffer from musculoskeletal disorders. Consequently, the increasing prevalence of neuromuscular diseases is driving the growth of the cryostat market.

The upsurge in infectious diseases is significantly contributing to the upward trajectory of the cryostat market. Infectious diseases, stemming from various pathogens such as viruses, bacteria, fungi, or parasites, are increasingly common. The utilization of cryostats in managing infectious diseases is crucial due to the potential risks associated with handling such agents. Tissue samples often contain infectious agents, necessitating specialized handling, particularly for samples from individuals positive for certain diseases. For instance, statistics from the Office for National Statistics in the UK indicated an escalating infection rate by the week ending December 9, 2022, notably reaching 1.92% among individuals aged 35 to 69 years and 1.25% in school years 12 to 24. Hence, the mounting prevalence of infectious diseases is anticipated to fuel the expansion of the cryostat market.

Leading companies in the cryostat market are developing innovative products, such as helium recovery solutions, aimed at enhancing sustainability, lowering operational costs, and improving the efficiency of cryogenic systems. Helium recovery solutions are systems specifically designed to capture, recycle, and reuse helium, a precious and limited resource widely used in cryogenic applications like cryostats. For example, in April 2024, Bluefors, a UK-based manufacturer of cryogenic measurement systems, launched the Cryomech HeRL02-RM. This specialized helium recovery solution is intended for single Nuclear Magnetic Resonance (NMR) systems. The HeRL02-RM establishes a closed-loop system that captures boiled-off helium from NMR magnets, redirecting it through a vapor return line to a Pulse Tube Cryocooler-powered liquefier, where it is rapidly liquefied and returned to the magnet's helium bath.

Key players in the cryostat market are advancing technologies like zero-boil-off (ZBO) technology to minimize the loss of cryogenic fluids, enhance system efficiency, and lower maintenance costs. ZBO technology is designed to prevent the evaporation or loss of cryogenic fluids, such as liquid helium or liquid nitrogen, which tend to boil off due to temperature variations. For instance, in April 2023, INOXCVA, an India-based cryogenic engineering company, successfully manufactured India's first indigenously designed 4K helium cryostat for a whole-body 1.5T superconducting MRI magnet system. This cryostat incorporates zero-boil-off technology, significantly reducing helium loss during operation, thus making it more efficient and cost-effective.

In August 2022, Atlas Copco, a multinational industrial company based in Sweden, completed the acquisition of Montana Instruments Corporation for an undisclosed sum. This strategic acquisition is expected to significantly expand Atlas Copco's existing footprint in the cryogenic markets and strengthen its relationships with research and development customers. Moreover, it provides an additional avenue for Atlas Copco to penetrate emerging quantum technology-related markets, where commercial applications are progressively gaining traction. Montana Instruments Corporation, renowned for its expertise in cryostat manufacturing, became a part of Atlas Copco's portfolio through this acquisition.

Major companies operating in the cryostat market include Lake Shore Cryotronics Inc, Cryomech Inc, Epredia, Hacker Instruments & Industries Inc, Histo-Line Laboratories Srl, Jinhua YIDI Medical Appliance Co Ltd, SLEE Medical GmbH, Leica Biosystems, Lupetec Technologies, MEDITE Medical GmbH, Boeckeler Instruments Inc, Bright Instruments Ltd, Precision Cryogenics Systems Inc, Atico Medical Pvt Ltd, Biobase Biodusty Co Ltd, Cryofab Inc., Amos Scientific, Thermo Fisher Scientific Inc., Oxford Instruments, Star Cryoelectronics, Infrared laboratories, Attocube Systems, Montana Instruments, Quantum Design, ICE Oxford, Cryogenic Limited, Bluefors, Cryoquip, CryoMAgnetics, Vacree Technologies.

North America was the largest region in the cryostat market in 2024. Asia-Pacific is expected to be the fastest-growing region in the cryostat market during the forecast period. The regions covered in the cryostat market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa. The countries covered in the cryostat market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

A cryostat is a medical equipment designed to maintain tissue sections at a constant low temperature and slice them into thin sections for microscopic examination, facilitating the diagnosis of various diseases and ailments. It is instrumental in preserving frozen tissue samples.

The major types of cryostats include closed-cycle cryostats, continuous-flow cryostats, bath cryostats, and multistage cryostats. Closed-cycle cryostats are helium-free systems that enable cooling down to liquid helium temperatures without the use of traditional cryogens. The components of the system include dewars, transfer tubes, gas flow pumps, temperature controllers, high vacuum pumps, and microtone blades, with various cryogens such as helium and nitrogen. Cryostats find applications in various industries, including healthcare, energy and power, aeronautics, metallurgy, biotechnology, forensic science, and marine biology.

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The cryostat market consists of sales of single compressor, double compressor, rotary cryostat, and motorized cryostat. Values in this market are ‘factory gate’ values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods. The cryostat market is segmented into single compressor, double compressor, rotary cryostat and other cryostats.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

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