High Performance Liquid Chromatography Market Report 2025

The high performance liquid chromatography market size has grown strongly in recent years. It will grow from $4.83 billion in 2024 to $5.11 billion in 2025 at a compound annual growth rate (CAGR) of 5.8%. The growth in the historic period can be attributed to increased demand from pharmaceutical industry, pharmaceutical industry demand, food safety and quality control needs, environmental monitoring and regulation compliance, automation and workflow optimization.

The high performance liquid chromatography market size is expected to see strong growth in the next few years. It will grow to $6.52 billion in 2029 at a compound annual growth rate (CAGR) of 6.3%. The growth in the forecast period can be attributed to rising applications in biotechnology and life sciences, growing importance in food safety and analysis, automation and integration in laboratories, demand from contract research organizations (CROs) and analytical labs, emphasis on compliance and standardization. Major trends in the forecast period include rise in biotechnology applications, growing focus on food safety and analysis, environmental monitoring and analysis, shift towards automated and integrated systems, rising demand for analytical services.

An increase in the prevalence of chronic diseases is anticipated to drive the growth of the high-performance liquid chromatography (HPLC) market in the future. Chronic diseases, such as cancer, heart disease, stroke, diabetes, and arthritis, are long-lasting conditions that often require extensive medical attention. High-performance liquid chromatography is employed to analyze medications to verify their identity, provide quantitative data, and monitor the effectiveness of illness therapy. Additionally, HPLC can be used to enhance the understanding of normal and pathological processes in the human body through biological and therapeutic research prior to medication approval, thereby contributing to market growth. For example, in September 2023, the World Health Organization, a specialized agency of the United Nations based in Switzerland, reported that there were 41 million deaths globally attributed to non-communicable diseases (NCDs) or chronic diseases, accounting for 74% of all deaths each year. Among these, cardiovascular diseases accounted for 17.9 million deaths, cancer for 9.3 million, chronic respiratory diseases for 4.1 million, and diabetes for 2 million. Therefore, the rising prevalence of chronic diseases is propelling the growth of the high-performance liquid chromatography market.

The growth of the pharmaceutical sector is expected to significantly boost the high-performance liquid chromatography (HPLC) market moving forward. The pharmaceutical sector encompasses companies and organizations involved in the research, development, manufacturing, and commercialization of pharmaceutical drugs. The pharmaceutical industry relies on HPLC for quality control and assurance during the manufacturing process. HPLC is vital for analyzing the purity, identity, and potency of pharmaceutical compounds, ensuring that drugs meet regulatory standards before they enter the market. For instance, in March 2022, the Centers for Medicare & Medicaid Services, a US-based federal agency, published the 2021-2030 National Health Expenditure (NHE) report, which projected that national health spending is expected to increase by an average of 5.1% annually from 2021 to 2030, reaching nearly $6.8 trillion in total. Furthermore, it is anticipated that Medicare spending will rise at a rate of 7.2% annually, while Medicaid spending is expected to increase at a rate of 5.6% annually during the same period. Thus, the expansion of the pharmaceutical sector is driving the growth of the high-performance liquid chromatography (HPLC) market.

Technological advancements are a significant trend gaining traction in the high-performance liquid chromatography (HPLC) market. Key players in the market are developing sophisticated HPLC technologies, including integrated high-performance liquid chromatography (HPLC) and ultra-high performance liquid chromatography (UHPLC), along with various HPLC systems that feature dual-injection systems, multidimensional capabilities, and intermediate pressure options. These innovations enhance the technique's applicability for a diverse range of research applications. For example, in March 2023, Waters Corporation, a US-based analytical laboratory instrument and software company, launched the Alliance iS, an intelligent high-performance liquid chromatography (HPLC) system designed to improve accuracy and user-friendliness while minimizing compliance risks. This next-generation system incorporates proactive error detection and troubleshooting features, effectively reducing common errors by up to 40%. When combined with Waters' Empower Chromatography Software and eConnect HPLC Columns, the Alliance iS optimizes the process of obtaining precise measurements. This innovation is particularly advantageous for Quality Control (QC) laboratories, ensuring consistent adherence to quality, safety, and compliance standards, thereby supporting timely product delivery goals.

Leading companies in the high-performance liquid chromatography (HPLC) market are prioritizing product development and launches, such as advanced ultra-high-performance liquid chromatography (UHPLC), to maintain their market position. Ultra-high-performance liquid chromatography (UHPLC) refers to a state-of-the-art analytical instrument used in chromatography. For instance, in February 2022, Shimadzu Corporation, a Japan-based multinational known for manufacturing precision instruments and analytical tools, launched the Nexera XS inert, an advanced ultra-high-performance liquid chromatography (UHPLC) system designed for biopharmaceutical analysis. This innovative system addresses common challenges in biopharmaceutical research, including molecule adsorption and corrosion. The Nexera XS inert minimizes interaction with biopolymers, reducing sample loss and providing precise, reliable results. Its metal-free sample flow path and corrosion-resistant materials ensure stability even in harsh environments with high salt concentrations or extreme pH levels. This advancement improves sensitivity and data quality, representing a significant progression in biopharmaceutical research.

In June 2024, CatSci Ltd., a UK-based contract research organization, acquired Reach Separations for an undisclosed sum. This strategic acquisition enables CatSci to provide comprehensive chromatographic solutions, assisting clients from the discovery phase to manufacturing. The acquisition bolsters CatSci's capabilities in full asset development. Reach Separations, a UK-based firm specializing in chromatography for therapeutic analysis and purification, complements this enhanced offering.

Major companies operating in the high performance liquid chromatography market include Waters Corporation, Thermo Fisher Scientific Inc., Agilent Technologies Inc., Shimadzu Corporation, PerkinElmer Inc., Bio-Rad Laboratories Inc., Gilson LLC, Danaher Corporation, Sartorius AG, Tosoh Bioscience GmbH, JASCO Inc., IDEX Health & Science LLC, Bruker Corporation, Orochem Technologies Inc., Merck KGaA, Restek Corporation, Knauer GmbH, GL Sciences Inc., Hitachi High-Tech Corporation, Cecil Instruments Limited, SCION Instruments, YMC Co. Ltd., Valco Instruments Co. Inc., Spark Holland B.V., Teledyne Tekmar, Analytik Jena AG, Imtakt Corporation, Chromsystems Instruments & Chemicals GmbH, Advion Inc.

North America was the largest region in the high performance liquid chromatography market analysis in 2024. Asia-Pacific is expected to be the fastest-growing region in the high performance liquid chromatography market during the forecast period. The regions covered in the high performance liquid chromatography market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa. The countries covered in the high performance liquid chromatography market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

High-performance liquid chromatography (HPLC) is a technique employed for separating components within a mixture, allowing for the identification and quantification of each element. It plays a crucial role in quantitatively determining the plasma levels of drugs and their metabolites, particularly essential in the development of new medications and therapy monitoring.

The primary products associated with high-performance liquid chromatography include instruments, consumables, accessories, and software. High-performance liquid chromatography instrumentation comprises nine fundamental components, featuring data collection, an output system, and connective tubing and fittings. These tools find applications across various sectors such as clinical research, diagnostics, forensics, and others. They are utilized by diverse end users, including pharmaceutical and biotechnology companies, academic and research institutes, food and beverage companies, hospitals and clinics, environmental agencies, and other entities.

The high-performance liquid chromatography market research report is one of a series of new reports that provides high-performance liquid chromatography market statistics, including high-performance liquid chromatography industry global market size, regional shares, competitors with a high-performance liquid chromatography market share, detailed high-performance liquid chromatography market segments, market trends and opportunities, and any further data you may need to thrive in the high-performance liquid chromatography industry. This high-performance liquid chromatography market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.

The high-performance liquid chromatography market includes revenues earned by entities by providing reverse phase columns, normal phase columns, ion exchange columns, and size exclusion columns. The market value includes the value of related goods sold by the service provider or included within the service offering. Only goods and services traded between entities or sold to end consumers are included.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

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