Today, treatment options for cancer patients typically include surgery, radiation therapy, immunotherapy, and chemotherapy. While these therapies have saved lives and reduced pain and suffering, cancer still takes millions of lives every year around the world. Researchers are now developing advanced therapeutic strategies such as immunotherapy, targeted therapy, and combination nanotechnology for drug delivery. In addition, the identification of new biomarkers will potentiate early-stage diagnosis.
Molecular Targets and Cancer presents information about cancer diagnosis and therapy in a simple way. It covers several aspects of the topic with updated information on par with medical board levels. The book features contributions from experts and includes an overview of cancer from basic biology and pathology, classifications, surveillance, prevention, diagnosis, types of cancer, treatment and prognosis.
The second part of this book discusses specialized topics in clinical oncology which include the pathophysiology of various types of cancer, cancer screening, different types of cancer surgery, cancer stem cell-targeted immunotherapy, nanotechnology for precision medicine applications in cancer and cancer surveillance.
This comprehensive guide is a valuable resource for oncologists, researchers, and all medical professionals who work in cancer care and research.
Molecular Targets and Cancer presents information about cancer diagnosis and therapy in a simple way. It covers several aspects of the topic with updated information on par with medical board levels. The book features contributions from experts and includes an overview of cancer from basic biology and pathology, classifications, surveillance, prevention, diagnosis, types of cancer, treatment and prognosis.
The second part of this book discusses specialized topics in clinical oncology which include the pathophysiology of various types of cancer, cancer screening, different types of cancer surgery, cancer stem cell-targeted immunotherapy, nanotechnology for precision medicine applications in cancer and cancer surveillance.
This comprehensive guide is a valuable resource for oncologists, researchers, and all medical professionals who work in cancer care and research.
Table of Contents
Chapter 1 Cancer Types- Introduction
- Definition
- Nomenclature
- Characteristics of Benign and Malignant Tumours
- Classification
- Carcinoma
- Lung Cancer
- Breast Cancer
- Pancreatic Cancer
- Prostate Cancer
- Types of Prostate Cancer
- Acinar Adenocarcinoma
- Prostatic Ductal Adenocarcinoma
- Transitional Cell or Urethral Cancer
- Squamous Cell Cancer
- Small Cell Prostate Cancer
- Neuroendocrine Tumors
- Sarcoma
- Pathophysiology
- Approach to Diagnosis and Further Assessment
- Colorectal Cancer
- Epidemiology and Risk Factors
- Symptoms
- Screening
- Cervical Cancer
- Epidemiology
- Pathophysiology
- Sarcoma
- Bone Tumor
- Cartilage Tumor
- Liposarcoma
- Brain Tumor
- Mixed-Origin Carcinoma-Sarcoma Tumors
- Gastrointestinal Cancer
- Melanoma
- Skin Cancer
- Hematological Malignancies
- Leukemia
- Lymphoid Malignancy
- Germ Cell Tumors
- Testicular Germ Cell Tumors
- Ovarian Germ Cell Tumors
- Blastoma
- Neuroblastoma
- Conclusion
- Consent for Publication
- Conflict of Interest
- Acknowledgements
- References
- Fayez Alelyani, Anas Abdulhamid Seday, Mashael Al-Toub and Adnan Alwatban
- Introduction
- Biopsy
- Endoscopy
- Diagnostic Imaging
- The Use of Imaging Diagnoses
- Imaging Tests Are Used for Cancer in Many Ways
- Perfections of Imaging Diagnosis
- Imaging Scan Types
- Blood Tests (Tumor Markers)
- Tumor Markers (Cancer Biomarkers)
- Circulating Tumor Markers
- Ctcs
- Cea
- Psa
- Conclusion
- Consent for Publication
- Conflict of Interest
- Acknowledgement
- References
- Naif Alenazi, Ayisha Q. Alanazi, Mohammed W. Al-Rabia and Fahad Albisi
- Introduction
- Types of Cancer Surgery
- Diagnostic Surgery
- Open Biopsy
- Advantages of Open Biopsy
- Disadvantages of Open Biopsy
- Incisional Biopsy
- Punch Biopsy
- Excisional Biopsy
- Needle Biopsy
- Fine-Needle Aspiration
- Core Needle Biopsy
- Endoscopy
- Laparoscopy
- Laparotomy
- Analysis of the Biopsy Results
- Staging Surgery
- Clinical Staging and Pathological Staging
- Sentinel Lymph Node Mapping and Biopsy
- Curative Surgery
- Types of Curative Surgery
- Excisional Surgery
- Laser Surgery
- Cryosurgery
- Electrosurgery
- Mohs Micrographic Surgery
- Preoperative or Post-Operative Chemotherapy and Radiation
- Preoperative Chemotherapy and Radiation
- Post-Operative Chemotherapy and Radiation
- Preoperative Chemotherapy With Post-Operative Radiation Therapy
- Debulking
- Patient Suitability for Debulking
- Debulking for Ovarian Cancer
- Complications of Debulking
- Palliative Surgery
- Bowel Surgery
- Palliative Mastectomy
- Suture Ligation
- Insertion of a Feeding Tube
- Prevent Broken Bones
- Preventative Surgery
- Mastectomy
- Oophorectomy
- Colectomy
- Thyroidectomy
- Removal of Precancerous Polyps
- Reconstructive Surgery
- Breast Reconstructive Surgery
- Head and Neck Restorative Surgery
- Access Surgery
- Practicalities of Surgery
- Before Surgery
- Prepping for Surgery
- After Surgery
- Palliative Treatment
- Soft Tissue Cancer of the Head and Neck (Except Salivary Glands and Thyroid Gland) .
- Skin
- Malignant Melanoma (Including Skin, Ocular, or Mucosal Melanomas), as Described in Either A, B, or C
- Soft Tissue Sarcoma
- Lymphoma (Including Mycosis Fungoides But Excluding T-Cell Lymphoblastic Lymphoma)
- Leukemia
- Multiple Myeloma (Confirmed by Appropriate Serum or Urine Protein Electrophoresis and Bone Marrow Findings)
- Salivary Glands: Carcinoma or Sarcoma With Metastases Beyond the Regional Lymph Nodes
- Thyroid Gland
- Breast (Except Sarcoma)
- Skeletal System (Sarcoma)
- Maxilla, Orbit, or Temporal Fossa
- Nervous System
- Lungs
- Pleura or Mediastinum
- Esophagus or Stomach
- Small Intestine: Carcinoma, Sarcoma, or Carcinoid
- Large Intestine: (From Ileocecal Valve to and Including Anal Canal)
- Liver or Gallbladder: Cancer of the Liver, Gallbladder, or Bile Ducts Pancreas
- Kidneys, Adrenal Glands, or Ureters Carcinoma
- Urinary Bladder Carcinoma
- Cancers of the Female Genital Tract-Carcinoma or Sarcoma (Including Primary Peritoneal Carcinoma)
- Prostate Gland: Carcinoma
- Conclusion
- Consent for Publication
- Conflict of Interest
- Acknowledgement
- References
- Ravi Teja Chitturi Suryaprakash, Mohammad Ayman Abdulkarim Safi, Noufa Alonazi, Ahdab A. Alsieedi Dqg Omar Kujan
- Introduction
- Monoclonal Antibodies (Mabs)
- Classification of Chemotherapeutic Monoclonal (Cmmab) Antibodies
- Mechanism of Action of Monoclonal Antibodies for the Treatment of Cancer
- Constraint and Cost
- Targeted Therapy Using Small Molecules
- Small Molecules Blocking Pd1 and Pd-L1
- Small Molecules Blocking Ido1
- Small Molecules Targeting Tregs
- Small Molecules Activating Toll-Like Receptors (Tlrs)
- Small Molecules Activating Cgas/Sting Pathway
- Small Molecules Targeting Chemokine Receptors
- Other Small Molecule Inhibitors
- Ligand Targeted Therapy
- Transforming Growth Factor Β (Tgf-Β)
- Nkg2D Signalling Pathway
- B7 Family of Immune-Regulatory Ligands
- Targeting Csc by Car T-Cells
- Targeting Csc by Dendritic Cell-Based Vaccines
- Cancer Stem Cell-Targeted Immunotherapy
- Targeting Csc by Oncolytic Viruses
- Cancer Immunotherapy
- Non-Specific Tumor Immunotherapy
- Targeting Pattern Recognition Receptors (Prrs)
- Cytokine Based Therapy
- Immune Checkpoint Blockage
- Specific Immunotherapy
- Adoptive T Cell Transfer
- Tumor-Infiltrating Lymphocytes (Tils) Therapy
- Contents Foreword
Author
- Faris Q.B. Alenzi
