The immune system is highly complex, it senses foreign invaders, thus protecting the body. The adaptive arm of the immune system confers long-term protection, whereas the innate immune system confers immediate protection. In the case of the immune system, the pattern recognition receptors offer various modes of sensing the molecular patterns associated with pathogens.
Toll-like receptors (TLRs) are important mediators of inflammatory pathways in the gut which play a major role in mediating the immune responses towards a wide variety of pathogen-derived ligands and link adaptive immunity with the innate immunity.
This book covers the role of TLRs in several vector-borne Diseases. Starting with an introduction to these diseases, the book explains the different types of receptors involved in these diseases. The diseases are then covered in separate chapters, including: malaria, lymphatic filariasis, visceral leishmaniasis, dengue fever, chikungunya, West Nile fever, and Japanese encephalitis.
The book is a handy reference for researchers and trainees involved in clinical medicine and infection control. It can also serve as supplementary reading material for Students undertaking courses in biotechnology, public health, entomology, immunology, epidemiology, and life sciences.
Toll-like receptors (TLRs) are important mediators of inflammatory pathways in the gut which play a major role in mediating the immune responses towards a wide variety of pathogen-derived ligands and link adaptive immunity with the innate immunity.
This book covers the role of TLRs in several vector-borne Diseases. Starting with an introduction to these diseases, the book explains the different types of receptors involved in these diseases. The diseases are then covered in separate chapters, including: malaria, lymphatic filariasis, visceral leishmaniasis, dengue fever, chikungunya, West Nile fever, and Japanese encephalitis.
The book is a handy reference for researchers and trainees involved in clinical medicine and infection control. It can also serve as supplementary reading material for Students undertaking courses in biotechnology, public health, entomology, immunology, epidemiology, and life sciences.
Table of Contents
Chapter 1- Introduction to Vector Borne Diseases
- Introduction
- Chikungunya
- Leishmaniasis
- Malaria
- Dengue
- Concluding Remarks
- Consent for Publication
- Conflict of Interest
- Acknowledgement
- Introduction
- Brain and Pathogen Associated Molecular Patterns
- Cerebral Malaria and Tlrs
- Concluding Remarks
- Consent for Publication
- Conflict of Interest
- Acknowledgement
- References
- Introduction
- Malaria: Pathology in the Brain by Neuroimaging
- Novel Malaria Biomarkers
- Blood Brain Barrier in Cerebral Malaria
- Experimental Mouse Models for Potential Treatments for Human Cm
- Inhibitor Studies
- Diagnostic and Therapeutic Monitoring of Cerebral Malaria by Imaging
- Malaria and Toll-Like Receptors in the Brain
- Malaria Drugs and Mechanism of Action
- Concluding Remarks
- Consent for Publication
- Conflict of Interest
- Acknowledgement
- References
- Introduction
- Lymphatic Filariasis and Inflammation
- Concluding Remarks
- Consent for Publication
- Conflict of Interest
- Acknowledgement
- References
- Introduction
- Concluding Remarks
- Consent for Publication
- Conflict of Interest
- Acknowledgement
- References
- Introduction
- Concluding Remarks
- Consent for Publication
- Conflict of Interest
- Acknowledgement
- References
- Introduction
- Epidemiology of Chikv
- Concluding Remarks
- Consent for Publication
- Conflict of Interest
- Acknowledgement
- References
- Introduction
- Micrornas and West Nile Virus
- Myd88-/- and Tlr-/- and Wnv Infection
- Concluding Remarks
- Consent for Publication
- Conflict of Interest
- Acknowledgement
- References
- Introduction
- Jev and Inflammation Through Tlrs
- Micrornas and Jev
- Microglial Cells /Microrna and Jev
- Concluding Remarks
- Consent for Publication
- Conflict of Interest
- Acknowledgement
- References
- Subject Index
Author
- Jayalakshmi Krishnan
