Gene Synthesis Market Global Market Report 2024

The gene synthesis market has grown exponentially in recent years. It will grow from $2.8 billion in 2023 to $3.36 billion in 2024 at a compound annual growth rate (CAGR) of 20.1%. The expansion observed in the historical period can be ascribed to progress in genetic research, the upsurge in personalized medicine, heightened emphasis on biotechnology, growth within the biopharmaceutical sector, and the emergence of technological platforms for synthesis.

The gene synthesis market is expected to see exponential growth in the next few years. It will grow to $7.09 billion in 2028 at a compound annual growth rate (CAGR) of 20.5%. The anticipated expansion in the forecast period can be linked to the swift development of synthetic biology, the advent of CRISPR technology, a rising need for custom genes, progress in gene editing and therapy, and the widening applications in agriculture. Prominent trends in the forecast period encompass heightened accessibility due to cost reduction, tailored gene libraries for functional genomics, automation, and high-throughput synthesis, collaborative efforts in the biotechnology and pharmaceutical sectors, and an emphasis on ethical and regulatory considerations.

The anticipated growth in the gene synthesis market is expected to be driven by the increased prevalence of chronic infectious diseases. These diseases, caused by persistent pathogens, often endure in the body for extended periods, necessitating innovative approaches for their control. Gene synthesis offers a promising avenue to address chronic infectious diseases by facilitating the development of targeted vaccines, diagnostics, and therapeutics tailored to specific pathogens. This method holds the potential for speedier, more efficient interventions compared to traditional approaches, contributing to better control of infectious disease outbreaks. For example, the World Health Organization reported that tuberculosis (TB) caused 1.6 million deaths in 2021, making it the 13th leading global cause of death and the second leading infectious killer after COVID-19, surpassing HIV/AIDS. Hence, the surge in chronic infectious diseases is a driving force behind the gene synthesis market's growth.

The gene synthesis market is expected to benefit from the increasing demand for biofuels. Biofuels, derived from organic materials such as plants or animal waste, serve as a renewable alternative to conventional fossil fuels. Gene synthesis plays a crucial role in biofuel production by enabling the engineering of microorganisms with enhanced metabolic pathways for efficient organic material conversion into biofuels. The International Energy Agency (IEA) reported in December 2021 that global biofuel demand is projected to increase by 28%, or 41 billion liters, from 2021 to 2026. This rising demand for biofuels further propels the growth of the gene synthesis market.

The gene synthesis market is witnessing a surge in technological advancements, emerging as a prominent trend. Companies engaged in the gene synthesis market are strategically embracing new technologies to maintain their competitive positions. For example, in June 2021, DNA Script SAS, a French pioneer in DNA printing, introduced the SYNTAX platform - a benchtop nucleic acid printer leveraging Enzymatic DNA Synthesis (EDS) technology. The SYNTAX System, an integrated and automated printer, has the capability to simultaneously synthesize 96 DNA oligos, each up to 60 nucleotides long, suitable for applications in molecular biology and genomics processes. Notably, the SYNTAX System delivers fast and efficient results, producing 20mers in approximately 6 hours for same-day outcomes and generating up to 60mers in about 13 hours, facilitating overnight processing.

Major players in the gene synthesis market are channeling their efforts into offering innovative services that leverage advanced platforms, such as silicon-based DNA synthesis platforms. These platforms aim to address the growing demand for expedited delivery, providing a competitive edge. For instance, in November 2023, Twist Bioscience, a US-based biotechnology company, launched Express Genes, a rapid gene synthesis service promising a turnaround time of five to seven business days. Leveraging a silicon-based DNA synthesis platform, this service caters to researchers in both industry and academia who seek faster gene delivery. Express Genes seeks to offer a comprehensive solution for gene production needs, accommodating researchers who purchase DNA from suppliers and those independently synthesizing genes.

In March 2021, Integrated DNA Technologies Inc. (Danaher Corporation), a US-based biotechnology research company, acquired Swift Biosciences Inc. for an undisclosed amount. This strategic acquisition enhances IDT's offerings in next-generation sequencing (NGS) products and services, encompassing targeted sequencing solutions and other innovative NGS technologies. Swift Biosciences Inc., based in the US, specializes in next-generation sequencing (NGS).

Major companies operating in the gene synthesis market market report are Genscript Biotech Corporation, Brooks Automation Inc., Boster Biological Technology Ltd., Twist Bioscience Corp., ProteoGenix Inc., Biomatik Corporation, ProMab Biotechnologies Inc., Thermo Fisher Scientific Inc., Integrated DNA Technologies Inc., OriGene Technologies Inc., GenScript Corp., Eurofins Scientific SE, Merck KGaA, Codex DNA Inc., Genewiz Inc., Eurofins Genomics LLC, BioCat GmbH, Bioneer Pacific Co. Ltd., DNA2.0 Inc., Bio Basic Inc., Beijing SBS Genetech Co. Ltd., Creative Biogene Inc., Exonbio LLC., Trenzyme GmbH, AddLife AB, Polygen GmbH, GlobalSpec Inc., MACROGEN CO. LTD., Synbio Technologies LLC.

North America was the largest region in the gene synthesis market in 2023. Asia-Pacific is expected to be the fastest-growing region in the global gene synthesis market report during the forecast period. The regions covered in the gene synthesis market market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa. The countries covered in the gene synthesis market market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

The primary methods for gene synthesis include solid-phase synthesis, chip-based synthesis, and PCR-based enzyme synthesis. Solid-phase synthesis is a chemical compound synthesis method where the reactant molecule is attached to an insoluble material, and reagents are introduced in the solution phase. This encompasses diverse gene synthesis services such as antibody DNA synthesis, viral DNA synthesis, and others. These services find applications in gene and cell therapy development, vaccine development, disease diagnosis, among others. Gene synthesis is utilized by different end-users, including biotechnology and pharmaceutical companies, academic and government research institutes, as well as contract research organizations.

The gene synthesis market research report provides gene synthesis market statistics, including the gene synthesis industry's global market size, regional shares, competitors with a gene synthesis market share, detailed gene synthesis market segments, market trends and opportunities, and any further data you may need to thrive in the gene synthesis industry. This gene synthesis market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenarios of the industry.

The gene synthesis market includes revenues earned by entities by providing custom gene synthesis services, selling pre-made DNA constructs, genetic engineering, vaccine development, antibody discovery, protein engineering, licensing technology, forming partnerships, and collaborating on research projects. The market value includes the value of related goods sold by the service provider or included within the service offering. Only goods and services traded between entities or sold to end consumers are included.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.


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