The current volume continues the tradition of the Organic Syntheses series, providing carefully checked and edited experimental procedures that describe important synthetic methods, transformations, reagents, and synthetic building blocks or intermediates with demonstrated utility in organic synthesis. These significant and interesting procedures should prove worthwhile to many synthetic chemists working in increasingly diverse areas. A trusted guide for professionals in organic and medicinal chemistry in academia, government, and industries, including pharmaceuticals, fine chemicals, agrochemicals, and biotechnological products.
Table of Contents
Chapter 1 Synthesis of [(R)-DTBM-SEGPHOS]NiCl2 for the Enantioselective Acetal Formation from N-Propanoyl-1,3-Thiazinane-2-thione and Trimethyl Orthoformate
Chapter 2 Synthesis of Alkylboronic Esters from Alkyl Iodides
Chapter 3 Preparation of N-Formylamides by Oxidative Cleavage of N-Acylaminoacids
Chapter 4 Transition-Metal-Free Synthesis of an Aryl Boronate Ester through Base-Mediated Boryl Substitution of an Aryl Halide with a Silylborane
Chapter 5 A Convenient Method for the Removal of Tetrabutylammonium Salts from Desilylation Reactions
Chapter 6 Discussion Addendum for: Asymmetric Michael Reaction of Aldehydes and Nitroalkenes
Chapter 7 Preparation of a Donor-Acceptor Stenhouse Adduct (DASA): 5-((2Z,4E)-5-(Diethylamino)-2-hydroxypenta-2,4-dien-1-ylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione
Chapter 8 Preparation of MIDA Anhydride and Reaction with Boronic Acids
Chapter 9 Discussion Addendum for: Preparation of 1,1-Difluoroallenes by Difluorovinylidenation of Carbonyl Compounds
Chapter 10 Ethoxypillar[6]arene
Chapter 11 Organocatalytic Dimerization of Succinaldehyde
Chapter 12 Synthesis of Phenanthridinones via the Palladium-Catalyzed Annulation of Benzyne
Chapter 13 Synthesis of Triphenylene via the Palladium-Catalyzed Annulation of Benzyne
Chapter 14 Synthesis of (((1R,3S,3′S)-3,3′-Diethyl-3H,3′H-1,1′-spirobi[isobenzofuran]-7,7′-diyl)bis(oxy))bis(diphenylphosphane)
Chapter 15 Discussion Addendum for: Nickel-Catalyzed Cross-Coupling of Aryl Halides with Alkyl Halides: Ethyl 4-(4-(4-methylphenylsulfonamido)-phenyl)butanoate
Chapter 16 Discussion Addendum for: Detrifluoroacetylative Diazo Group Transfer: (E)-1-Diazo-4-phenyl-3-buten-2-one
Chapter 17 Preparation of 9-Azabicyclo[3.3.1]nonane-N-oxyl (ABNO)
Chapter 18 Discussion Addendum for: Synthesis of N-Boc-N-Hydroxymethyl-L-phenylalaninal and Methyl trans-Oxazolidine-5-carboxylate, Chiral Synthons for threo-β-Amino-α-hydroxy Acids
Chapter 19 Large Scale Oxidative Cyclization of (E)-Hex-3-en-1-yl(4-Methoxyphenyl)sulfamate
Chapter 20 Synthesis of Carboxylic Acids from Benzamide Precursors Using Nickel Catalysis
Chapter 21 Stereoselective Synthesis of Dimethyl 4(S)-Allyl-N-Boc-L-glutamate and Related Congeners
Chapter 22 Discussion Addendum for: Preparation of Diisopropylammonium Bis(catecholato)cyclohexylsilicate
Chapter 23 Preparation of 1,2:5,6-Di-O-cyclohexylidene-D-mannitol and 2,3-Cyclohexylidene-D-glyceraldehyde
Chapter 24 Transformation of a N,N-Dimethylaniline N-oxide into a Tetrahydroquinoline Scaffold via a Formal Polonovski-Povarov Reaction
Index
