The revised guide to the diagnosis, management, and treatment of blood disorders and cancer in children
Children with blood disorders and cancer are a unique population that require specialized diagnostic considerations and management. The Handbook of Pediatric Hematology and Oncology has been designed to provide clinicians of all levels with practical guidance through an up-to-date algorithmic approach to these conditions. Assembled by a team of experts from the world-class Children's Hospital & Research Center Oakland, this updated third edition:
- Presents up-to-date management and treatment guidelines for the most common pediatric blood disorders and malignancies
- Provides an updated algorithmic approach for the diagnosis and management of the most common conditions and suggested readings
- Utilizes rapid-referral tables containing visual representations of symptoms, lab findings, differentials, and treatment guidance
- Incorporates case studies covering different hematologic and oncologic conditions, such as hemolytic anemia, sickle cell disease, hemophilia, neuroblastoma, and sarcomas of the soft tissue and bone
- Includes a useful formulary that lists chemotherapy agents, dosing, mechanism of action, pregnancy category, indications, and side effects
- Covers transfusion medicine, stem cell transplantation, management of central venous catheters, acute pain management, oncologic emergencies, and chemotherapy basics
With its direct guidance and portable design, the Handbook of Pediatric Hematology and Oncology: Children's Hospital & Research Center Oakland, Third Edition, will prove an invaluable resource to medical students, trainees and residents, pediatric hematology and oncology nurses, pediatricians, and early-career providers in pediatric hematology/oncology.
Table of Contents
Preface ix
Acknowledgments xi
1 Approach to the Anemic Child 1
2 Hemolytic Anemia 15
3 Sickle Cell Disease 27
4 Thalassemia 51
5 Transfusion Medicine 63
6 Chelation Therapy 79
7 Approach to the Bleeding Child 85
8 Von Willebrand Disease 95
9 Hemophilia 103
10 Thrombophilia 111
11 The Neutropenic Child 119
12 Thrombocytopenia 133
13 Evaluation of the Child with a Suspected Malignancy 157
14 Oncologic Emergencies 173
15 Acute Leukemias 191
16 Central Nervous System Tumors 211
17 Hodgkin and Non‐Hodgkin Lymphoma 227
18 Wilms Tumor 239
19 Neuroblastoma 245
20 Sarcomas of the Soft Tissues and Bone 253
21 Germ Cell Tumors 265
22 Rare Tumors of Childhood 275
23 Histiocytic Disorders 287
24 Hematopoietic Stem Cell Transplantation 295
25 Supportive Care of the Child with Cancer 313
26 Central Venous Catheters 323
27 Management of Fever in the Child with Cancer 333
28 Acute Pain Management in the Inpatient Setting 347
29 Palliative Care 361
30 Chemotherapy Basics 377
31 Guide to Procedures 393
32 Treatment of Chemotherapy Extravasations 403
Formulary 409
Index 489
