The second edition of the leading introduction to blood science, with updated new illustrations and case studies
Blood Science: Principles and Pathology integrates hematology and blood transfusion, clinical biochemistry, and immunology to provide a thorough introduction to this rapidly expanding discipline. Reflecting recent changes in education and training for healthcare scientists, this comprehensive textbook covers the analytical techniques used in blood science, the diagnosis and management of various blood disorders, and more.
Fully revised, the second edition presents new case studies and high-quality images throughout, illustrating the practical skills and knowledge required by today’s undergraduate students and practitioners. Detailed yet accessible chapters contain learning objectives and summaries, links to further readings and resources, and real-world case studies with easy-to-follow interpretations. Throughout the text, the authors highlight how laboratory data and clinical details are used to investigate patients with actual or suspected diseases in real-world scenarios: - Multi-disciplinary view merging biochemical, hematological, immunological, and genetical knowledge into a single discipline: Blood science- Discusses advances in molecular genetics identifying mutations resulting in the occurrence of certain pathological conditions such as leukaemia- Presents an expanded concluding chapter with detailed case reports that integrate biochemistry, immunology, and haematology, which all contribute to the investigation of respective conditions- Explains the potentials for developing tests such as non-coding RNAs- Offers further reading suggestions to dive even deeper into discussed subjects and concepts
Designed to meet the needs of undergraduate students taking blood science modules in biomedical, biological, and healthcare science programs, Blood Science: Principles and Pathology, Second Edition is also an invaluable guide for new graduates entering the field, as well as those training for professional qualifications or working with blood samples in laboratory-based environments.
Table of Contents
Preface
Acknowledgements
List of Abbreviations
About the Companion Website
1. Introduction to Blood Science
2. Analytical Techniques in Blood Science
3. The Physiology of the Red Blood Cell
4. The Pathology of the Red Blood Cell
5. White Blood Cells in Health and Disease
6. White Blood Cell Malignancy
7. The Physiology and Pathology of Haemostasis
8. The Diagnosis and Management of Disorders of Haemostasis
9. Immunopathology
10. Immunogenetics and Histocompatibility
11. Blood Transfusion
12. Waste products, electrolytes, and renal disease
13. Hydrogen ions, pH, and acid-base disorders
14. Glucose, lipids, and atherosclerosis
15. Calcium, phosphate, magnesium, and bone disease
16. Nutrients and Gastrointestinal Disorders
17. Liver function tests and plasma proteins
18. Endocrinology
19. Cancer and tumour markers
20. Inherited Metabolic Disorders
21. Drugs and Poisons
22. Case Reports in Blood Science
Further Reading
Appendix 1: Reference Ranges
Glossary
Index
