The global gene synthesis market size was valued at USD 1.9 billion in 2023. It is expected to grow at a CAGR of 18.4% during the forecast period of 2024-2032, driven by technological advancements in synthesis efficiency across the globe. The market is experiencing robust growth and is expected to reach USD 8.5 billion by 2032.
The rise of the synthetic biology field, which combines biology with engineering principles to design and construct new biological parts, devices, and systems, is another major driver. Synthetic genes are crucial components in synthetic biology, used to create novel organisms or modify existing ones for various purposes, including biofuel production, bioremediation, and agriculture.
The technical limitations of current gene synthesis technologies, including errors in gene assembly and difficulties in synthesizing long DNA sequences, represent additional hurdles. Overcoming these challenges requires ongoing research and development efforts to improve accuracy and efficiency.
These trends indicate a market that is rapidly evolving, fueled by technological innovations and expanding into new applications and regions. As the gene synthesis market continues to grow, these trends will shape its trajectory, offering new opportunities and challenges for stakeholders in the field.
Together, these segments are poised to propel the gene synthesis market forward, supported by technological advancements, growing applications in research and biotechnology, and the expanding synthetic biology field. This comprehensive approach to gene synthesis, incorporating hardware, consumables, and digital solutions, is expected to drive significant market expansion in the forecast period.
The "others" category captures emerging and specialized gene synthesis services that cater to niche applications, further broadening the market's scope. The diversification in gene synthesis types reflects the evolving complexity and specificity of research and commercial projects in biotechnology, underpinning the market's growth trajectory as technologies advance and applications widen.
The development of therapeutic antibodies, another significant application, utilizes gene synthesis for creating monoclonal antibodies for a wide range of diseases, from cancer to autoimmune disorders. The "others" category encompasses a broad range of emerging applications, including drug discovery, metabolic engineering, and environmental biotechnology, each contributing to the market's expansion. This segmentation underscores the integral role of gene synthesis across diverse biotechnological and pharmaceutical research areas, poised for significant growth as advancements in synthesis technologies continue to broaden the scope and efficiency of applications.
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Global Gene Synthesis Market Analysis
The global gene synthesis market is experiencing significant growth, driven by rapid advancements in synthetic biology and an increasing demand for synthetic genes across various sectors, including biotechnology, pharmaceuticals, and academic research. Gene synthesis, the process of artificially constructing genetic material in vitro, has become an invaluable tool for researchers and companies focusing on drug discovery, vaccine development, and genetic engineering.Market Drivers
Several key drivers are propelling the growth of the gene synthesis market. First, there's a growing demand for personalized medicine, which relies on genetic information to tailor treatments to individual patients. This has led to an increased need for synthetic genes in drug development and diagnostic processes. Additionally, advancements in DNA synthesis technologies have significantly reduced the cost and time required to synthesize genes, making gene synthesis more accessible and affordable for a wider range of applications.The rise of the synthetic biology field, which combines biology with engineering principles to design and construct new biological parts, devices, and systems, is another major driver. Synthetic genes are crucial components in synthetic biology, used to create novel organisms or modify existing ones for various purposes, including biofuel production, bioremediation, and agriculture.
Market Challenges
Despite the market's growth, there are challenges that need addressing. Intellectual property and ethical issues surrounding the creation and use of synthetic genes pose significant concerns. The potential misuse of gene synthesis technology for harmful purposes, such as bioterrorism, also raises biosecurity issues, necessitating strict regulations and oversight.The technical limitations of current gene synthesis technologies, including errors in gene assembly and difficulties in synthesizing long DNA sequences, represent additional hurdles. Overcoming these challenges requires ongoing research and development efforts to improve accuracy and efficiency.
Global Gene Synthesis Market Trends
The global gene synthesis market is characterized by several emerging trends that underscore its dynamic nature and the significant impact of technological advancements. These trends not only reflect the current state of the market but also hint at its future direction, emphasizing the growing role of gene synthesis in various scientific and commercial applications.1. Technological Advancements in Synthesis Efficiency
One of the most notable trends is the continuous improvement in gene synthesis technologies. Innovations in synthesis methods, such as automated DNA synthesizers and microfluidic devices, have increased efficiency, reduced error rates, and lowered the cost of gene synthesis. These advancements have made gene synthesis more accessible to a broader range of researchers and companies, facilitating more complex genetic engineering projects.2. Rise of Custom and Large-Scale Gene Synthesis
There's an increasing demand for custom gene synthesis services that cater to specific research needs, including the synthesis of long or complex DNA sequences. Additionally, large-scale gene synthesis projects, which are crucial for synthetic biology applications like genome engineering and the development of synthetic organisms, are becoming more common. This trend is driven by the expanding capabilities of gene synthesis platforms to handle large volumes of custom orders efficiently.3. Expansion into New Applications
Gene synthesis is finding new applications beyond traditional fields. In healthcare, it's pivotal in developing personalized medicine, vaccine design, and therapeutic proteins. In agriculture, gene synthesis is used to engineer crops for better yield, disease resistance, and nutritional value. Environmental applications, such as bioremediation using genetically engineered microbes, are also on the rise. This diversification is expanding the market into new sectors.4. Integration with CRISPR and Other Genome Editing Technologies
The integration of gene synthesis with CRISPR-Cas9 and other genome editing technologies is a significant trend. Gene synthesis provides custom DNA templates for CRISPR applications, enabling precise genome modifications. This synergy is accelerating research in genetics, improving the development of gene therapies, and enhancing the capabilities of synthetic biology.5. Ethical, Regulatory, and Biosecurity Considerations
As gene synthesis technology becomes more powerful, ethical, regulatory, and biosecurity issues become increasingly important. There's a growing focus on developing guidelines and regulations to ensure the responsible use of gene synthesis, particularly concerning dual-use research that could be misapplied. The industry is actively engaging with policymakers, researchers, and the public to address these concerns.6. Globalization and Collaboration
The gene synthesis market is becoming more globalized, with significant growth in regions outside of traditional hubs in North America and Europe, particularly in Asia Pacific. International collaborations between companies, academic institutions, and governments are fostering innovation and driving the market's expansion. These partnerships are crucial for sharing knowledge, technology, and resources, contributing to the global advancement of gene synthesis applications.These trends indicate a market that is rapidly evolving, fueled by technological innovations and expanding into new applications and regions. As the gene synthesis market continues to grow, these trends will shape its trajectory, offering new opportunities and challenges for stakeholders in the field.
Global Gene Synthesis Market Segmentation
Market Breakup by Component
- Synthesizer
- Consumables
- Software and Services
Together, these segments are poised to propel the gene synthesis market forward, supported by technological advancements, growing applications in research and biotechnology, and the expanding synthetic biology field. This comprehensive approach to gene synthesis, incorporating hardware, consumables, and digital solutions, is expected to drive significant market expansion in the forecast period.
Market Breakup by Gene Type
- Standard Gene
- Express Gene
- Complex Gene
- Others
Market Breakup by Gene Synthesis Type
- Gene Library Synthesis
- Custom Gene Synthesis
- Others
The "others" category captures emerging and specialized gene synthesis services that cater to niche applications, further broadening the market's scope. The diversification in gene synthesis types reflects the evolving complexity and specificity of research and commercial projects in biotechnology, underpinning the market's growth trajectory as technologies advance and applications widen.
Market Breakup by Method
- Solid Phase
- Synthesis Chip-Based DNA Synthesis
- PCR-Based Enzyme Synthesi
- Others
Market Breakup by Application
- Synthetic Biology
- Genetic Engineering
- Vaccine Design
- Therapeutics Antibodies
- Others
The development of therapeutic antibodies, another significant application, utilizes gene synthesis for creating monoclonal antibodies for a wide range of diseases, from cancer to autoimmune disorders. The "others" category encompasses a broad range of emerging applications, including drug discovery, metabolic engineering, and environmental biotechnology, each contributing to the market's expansion. This segmentation underscores the integral role of gene synthesis across diverse biotechnological and pharmaceutical research areas, poised for significant growth as advancements in synthesis technologies continue to broaden the scope and efficiency of applications.
Market Breakup by End User
- Academic and Research Institutes
- Diagnostics Laboratories
- Biotech & Pharmaceutical Companies
- Others
Market Breakup by Region
- North America
- Europe
- Asia Pacific
- Latin America
- Middle East and Africa
Global Gene Synthesis Market Competitive Landscape
The global gene synthesis market is marked by a competitive landscape featuring a mix of established companies and emerging players, each contributing to the field's growth with their specialized offerings. Creative Biogene, Bioneer Pacific, B. Braun Melsungen AG, MACROGEN CO., LTD., General Biosystems, Inc., ATDBio Ltd (Subsidiary of Biotage), OriGene Technologies, Inc., Integrated DNA Technologies, Inc., Thermo Fisher Scientific, Inc., ProMab Biotechnologies, Inc., Biomatik, ProteoGenix, Inc., Twist Bioscience, Boster Biological Technology, Brooks Automation, Inc. (GENEWIZ) and GenScript are known for their innovative gene synthesis solutions, catering to a wide range of research and industrial applications.Key Questions Answered in This Report
- What is the current and future performance of the global gene synthesis market?
- What are the main factors driving the increasing demand and accessibility of gene synthesis in various fields?
- What challenges and concerns are impacting the growth of the gene synthesis market, and how are they being addressed?
- How are innovations in gene synthesis technologies enhancing efficiency, reducing costs, and facilitating complex genetic engineering projects?
- How are the segments of synthesizers, consumables, and software and services collectively driving growth in the global gene synthesis market?
- How is the diversity in gene types, including standard, express, and complex genes, addressing varied applications and driving growth in the gene synthesis market?
- How are different types of gene synthesis, including gene library and custom synthesis, catering to specific market demands and driving the sector's growth?
- How are diverse end-user segments, including academic, diagnostics, and biotech sectors, driving the expansion and application diversity of the gene synthesis market?
- How is the competitive landscape of the global gene synthesis market shaped by the mix of established companies and emerging innovators?
- What are the main players/companies in the market?
Key Benefits for Stakeholders
- The industry report offers a comprehensive quantitative analysis of various market segments, historical and current market trends, market forecasts, and dynamics of the global gene synthesis market from 2017-2032.
- The research report provides the latest information on the market drivers, challenges, and opportunities in the global gene synthesis market.
- The study maps the leading, as well as the fastest-growing, regional markets. It further enables stakeholders to identify the key country-level markets within each region.
- Porter's five forces analysis assists stakeholders in assessing the impact of new entrants, competitive rivalry, supplier power, buyer power, and the threat of substitution. It helps stakeholders to analyze the level of competition within the global gene synthesis industry and its attractiveness.
- The competitive landscape allows stakeholders to understand their competitive environment and provides insight into the current positions of key players in the market.
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Table of Contents
1 Preface
3 Global Gene Synthesis Market Overview
4 Global Gene Synthesis Market Landscape
5 Global Gene Synthesis Market Dynamics
6 Global Gene Synthesis Market Segmentation
7 North America Gene Synthesis Market
8 Europe Gene Synthesis Market
9 Asia Pacific Gene Synthesis Market
10 Latin America Gene Synthesis Market
11 Middle East and Africa Gene Synthesis Market
12 Regulatory Framework
13 Patent Analysis
14 Grants Analysis
15 Clinical Trials Analysis
16 Funding and Investment Analysis
17 Partnership and Collaborations Analysis
18 Supplier Landscape
20 Company Competitiveness Analysis (Additional Insight)
21 Payment Methods (Additional Insight)
Companies Mentioned
- ATDBio Ltd
- General Biosystems
- Macrogen CO.
- Boster Biological Technology
- Creative Biogene
- Bioneer Pacific,
- Exonbio
- trenzyme GmbH
- Twist Bioscience
- BioCat GmbH
- OriGene Technologies, Inc.
- Integrated DNA Technologies
- Eurofins Scientific
- NZYTech
- Genes and Enzymes
Methodology
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Table Information
Report Attribute | Details |
---|---|
No. of Pages | 140 |
Published | May 2024 |
Forecast Period | 2024 - 2032 |
Estimated Market Value ( USD | $ 2.2 Billion |
Forecasted Market Value ( USD | $ 8.5 Billion |
Compound Annual Growth Rate | 18.4% |
Regions Covered | Global |
No. of Companies Mentioned | 15 |