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Europe Recombinant Protein Manufacturing Services Market Size, Share & Trends Analysis Report By Service Type (Pre-clinical & Clinical), By Host Cell (Mammalian, Bacterial), By End-use, By Country, And Segment Forecasts, 2023 - 2030

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    Report

  • 98 Pages
  • August 2023
  • Region: Europe
  • Grand View Research
  • ID: 5876178
The Europe recombinant protein manufacturing services market size is expected to reach USD 3.26 billion in 2030, growing at 14.88% CAGR from 2023 to 2030. Recombinant proteins have many applications in the field of biotechnology research and medicine. Furthermore, recombinant protein manufacturing is one of the effective procedures utilized in the life sciences sector, which significantly impacts advanced healthcare.

Proteins are altered using specific procedures to produce recombinant proteins. These recombinant proteins are then encoded by genes to produce massive amounts of protein, which are then utilized to manufacture therapeutic products. Increased government initiatives and investment in the field of life sciences are likely to drive Europe recombinant protein manufacturing services industry expansion.

In addition, the growing demand and complexity of manufacturing laws & regulations and the rising maintenance cost of GMP certification at sites are driving the adoption of outsourced manufacturing & packaging models. Outsourcing is also enabling companies to release capital and cut overhead costs. Furthermore, the biotech companies in the UK are outperforming their European peers in terms of securing early-stage funding. From 2018 to 2020, biotech start-ups in the country raised USD 3.6 billion, a 20% increase from the amount raised from 2015 to 2017. As a result, the R&D services landscape in the country is expected to witness significant growth in the coming decade.

In Europe, several leading companies offer recombinant protein production services, including Lonza; GenScript; Merck KGaA; Kaneka Eurogentec S. A.; ExcellGene SA., and others, creating growth prospects for outsourcing activities. Key players in the region are expanding their manufacturing capabilities to cater to the growing outsourcing demand in Europe.

For instance, in October 2022, Merck KGaA opened a new commercial facility for its Millipore CTDMO Services in Martillac, France. The new 2,700 sq. m. facility was built for producing drug substances, including monoclonal antibodies and other recombinant proteins. Similarly, in August 2019, Fujifilm acquired Biogen’s Denmark-based biologics manufacturing site for around USD 890 million. Such initiatives are expected to create lucrative growth opportunities in the recombinant protein manufacturing services industry over the coming decade.

Although the presence of strong regulations helps safeguard patient health and safety, it may lead to delayed approvals, high manufacturing costs, and challenges in compliance, which may hamper the development of recombinant protein-based products, limiting the growth of manufacturing services.

Europe Recombinant Protein Manufacturing Services Market Report Highlights

  • By service type, the commercial production services segment accounted for the largest share of 58.82% in 2022. This attributed to the growing accessibility of high-yield expression systems
  • By host cell, the mammalian segment accounted for the largest share of 54.70% in 2022. The market is expanding due to growing demand for mammalian cells from pharmaceutical and biotech companies
  • By end-use, the pharmaceutical & biotechnology companies segment accounted for the largest share of 78.79% in 2022. Recombinant proteins have gained immense traction in the biotechnology & pharmaceutical industries, wherein they can be utilized to create vaccines and treatments for various illnesses and protein manufacturing services
  • Germany held a large share of total revenues in 2022. This is mostly due to the presence of major market participants, increased research spending, and the availability of well-established healthcare infrastructure, which is driving market growth across the region

Table of Contents

Chapter 1. Methodology and Scope
1.1. Market Segmentation and Scope
1.2. Market Definitions
1.2.1. Information analysis
1.2.2. Market formulation & data visualization
1.2.3. Data validation & publishing
1.3. Research Assumptions
1.4. Information Procurement
1.4.1. Primary Research
1.5. Information or Data Analysis
1.6. Market Formulation & Validation
1.7. Market Model
1.8. Europe Market: CAGR Calculation
1.9. Objectives
1.9.1. Objective 1
1.9.2. Objective 2
Chapter 2. Executive Summary
2.1. Market Snapshot
2.2. Segment Snapshot
2.3. Competitive Landscape Snapshot
Chapter 3. Market Variables, Trends, & Scope
3.1. Market Lineage Outlook
3.1.1. Parent Market Outlook
3.1.2. Related/Ancillary Market Outlook
3.2. Market Trends and Outlook
3.3. Market Dynamics
3.3.1. Increasing adoption of outsourcing models for recombinant protein manufacturing
3.3.2. The increasing scope of applications for recombinant protein-based products
3.3.3. Increasing the use of recombinant proteins in research-use activities
3.4. Market Restraint Analysis
3.4.1. Stringent regulations associated with recombinant protein-based biopharmaceuticals
3.5. Business Environment Analysis
3.5.1. SWOT Analysis; By Factor (Political & Legal, Economic And Technological)
3.5.2. Porter’s Five Forces Analysis
3.6. COVID-19 Impact Analysis
Chapter 4. Service Type Business Analysis
4.1. Europe Recombinant Protein Manufacturing Services Market: Service Type Movement Analysis
4.2. Pre-clinical & Clinical Services
4.2.1. Pre-clinical & Clinical Services Market, 2018 - 2030 (USD Million)
4.3. Commercial Production Services
4.3.1. Commercial Production Services Market, 2018 - 2030 (USD Million)
Chapter 5. Host Cell Business Analysis
5.1. Europe Recombinant Protein Manufacturing Services Market: Host Cell Movement Analysis
5.2. Mammalian Cells
5.2.1. Mammalian Cells Market, 2018 - 2030 (USD Million)
5.3. Bacterial Cells
5.3.1. Bacterial Cells Market, 2018 - 2030 (USD Million)
5.4. Insect Cells
5.4.1. Insect Cells Market, 2018 - 2030 (USD Million)
5.5. Yeast & Fungi
5.5.1. Yeast & Fungi Market, 2018 - 2030 (USD Million)
5.6. Others
5.6.1. Others Market, 2018 - 2030 (USD Million)
Chapter 6. End-use Business Analysis
6.1. Europe Recombinant Protein Manufacturing Services Market: End-use Movement Analysis
6.2. Pharmaceutical & Biotechnology Companies
6.2.1. Pharmaceutical & Biotechnology Companies Market, 2018 - 2030 (USD Million)
6.3. Academic & Research Institutes
6.3.1. Academic & Research Institutes Market, 2018 - 2030 (USD Million)
Chapter 7. Country Business Analysis
7.1. Europe Recombinant Protein Manufacturing Services Market Share By Country, 2022 & 2030
7.2. Europe
7.2.1. Europe Recombinant Protein Manufacturing Services Market, 2018 - 2030 (USD Million)
7.2.2. Germany
7.2.2.1. Key Country Dynamics
7.2.2.2. Competitive Scenario
7.2.2.3. Regulatory Framework
7.2.2.4. Target Disease Prevalence
7.2.2.5. Germany Recombinant Protein Manufacturing Services Market, 2018 - 2030 (USD Million)
7.2.3. UK
7.2.3.1. Key Country Dynamics
7.2.3.2. Competitive Scenario
7.2.3.3. Regulatory Framework
7.2.3.4. Target Disease Prevalence
7.2.3.5. UK Recombinant Protein Manufacturing Services Market, 2018 - 2030 (USD Million)
7.2.4. France
7.2.4.1. Key Country Dynamics
7.2.4.2. Competitive Scenario
7.2.4.3. Regulatory Framework
7.2.4.4. Target Disease Prevalence
7.2.4.5. France Recombinant Protein Manufacturing Services Market, 2018 - 2030 (USD Million)
7.2.5. Italy
7.2.5.1. Key Country Dynamics
7.2.5.2. Competitive Scenario
7.2.5.3. Regulatory Framework
7.2.5.4. Target Disease Prevalence
7.2.5.5. Italy Recombinant Protein Manufacturing Services Market, 2018 - 2030 (USD Million)
7.2.6. Spain
7.2.6.1. Key Country Dynamics
7.2.6.2. Competitive Scenario
7.2.6.3. Regulatory Framework
7.2.6.4. Target Disease Prevalence
7.2.6.5. Spain Recombinant Protein Manufacturing Services Market, 2018 - 2030 (USD Million)
7.2.7. Denmark
7.2.7.1. Key Country Dynamics
7.2.7.2. Competitive Scenario
7.2.7.3. Regulatory Framework
7.2.7.4. Target Disease Prevalence
7.2.7.5. Denmark Recombinant Protein Manufacturing Services Market, 2018 - 2030 (USD Million)
7.2.8. Sweden
7.2.8.1. Key Country Dynamics
7.2.8.2. Competitive Scenario
7.2.8.3. Regulatory Framework
7.2.8.4. Target Disease Prevalence
7.2.8.5. Sweden Recombinant Protein Manufacturing Services Market, 2018 - 2030 (USD Million)
7.2.9. Norway
7.2.9.1. Key Country Dynamics
7.2.9.2. Competitive Scenario
7.2.9.3. Regulatory Framework
7.2.9.4. Target Disease Prevalence
7.2.9.5. Norway Recombinant Protein Manufacturing Services Market, 2018 - 2030 (USD Million)
7.2.10. Switzerland
7.2.10.1. Key Country Dynamics
7.2.10.2. Competitive Scenario
7.2.10.3. Regulatory Framework
7.2.10.4. Target Disease Prevalence
7.2.10.5. Switzerland Recombinant Protein Manufacturing Services Market, 2018 - 2030 (USD Million)
7.2.11. Netherlands
7.2.11.1. Key Country Dynamics
7.2.11.2. Competitive Scenario
7.2.11.3. Regulatory Framework
7.2.11.4. Target Disease Prevalence
7.2.11.5. Netherlands Recombinant Protein Manufacturing Services Market, 2018 - 2030 (USD Million)
Chapter 8. Competitive Landscape
8.1. Company Categorization
8.2. Strategy Mapping
8.3. Company Profiles/Listing
8.3.1. Lonza
8.3.1.1. Overview
8.3.1.2. Financial Performance (Net Revenue/Sales/EBITDA/Gross Profit)
8.3.1.3. Product Benchmarking
8.3.1.4. Strategic Initiatives
8.3.2. Boehringer Ingelheim International GmbH
8.3.2.1. Overview
8.3.2.2. Financial Performance (Net Revenue/Sales/EBITDA/Gross Profit)
8.3.2.3. Product Benchmarking
8.3.2.4. Strategic Initiatives
8.3.3. FUJIFILM Diosynth Biotechnologies
8.3.3.1. Overview
8.3.3.2. Financial Performance (Net Revenue/Sales/EBITDA/Gross Profit)
8.3.3.3. Product Benchmarking
8.3.3.4. Strategic Initiatives
8.3.4. Merck KGaA
8.3.4.1. Overview
8.3.4.2. Financial Performance (Net Revenue/Sales/EBITDA/Gross Profit)
8.3.4.3. Product Benchmarking
8.3.4.4. Strategic Initiatives
8.3.5. Bruker (InVivo BioTech Services GmbH)
8.3.5.1. Overview
8.3.5.2. Financial Performance (Net Revenue/Sales/EBITDA/Gross Profit)
8.3.5.3. Product Benchmarking
8.3.5.4. Strategic Initiatives
8.3.6. Sino Biological, Inc.
8.3.6.1. Overview
8.3.6.2. Product Benchmarking
8.3.6.3. Strategic Initiatives
8.3.7. GenScript
8.3.7.1. Overview
8.3.7.2. Financial Performance (Net Revenue/Sales/EBITDA/Gross Profit)
8.3.7.3. Product Benchmarking
8.3.7.4. Strategic Initiatives
8.3.8. Kaneka corporation (Kaneka Eurogentec S.A)
8.3.8.1. Overview
8.3.8.2. Financial Performance (Net Revenue/Sales/EBITDA/Gross Profit)
8.3.8.3. Product Benchmarking
8.3.8.4. Strategic Initiatives
8.3.9. Polyplus Transfection (Xpress Biologics)
8.3.9.1. Overview
8.3.9.2. Product Benchmarking
8.3.9.3. Strategic Initiatives
8.3.10. Boster Biological Technology
8.3.10.1. Overview
8.3.10.2. Product Benchmarking
8.3.10.3. Strategic Initiatives
8.3.11. Trenzyme GmbH
8.3.11.1. Overview
8.3.11.2. Product Benchmarking
8.3.11.3. Strategic Initiatives
List of Tables
Table 1 List of secondary sources
Table 2 List of abbreviations
Table 3 Europe Recombinant Protein Manufacturing Services Market by Service Type, 2018 - 2030 (USD Million)
Table 4 Europe Recombinant Protein Manufacturing Services Market by Host Cell, 2018 - 2030 (USD Million)
Table 5 Europe Recombinant Protein Manufacturing Services Market by End-use, 2018 - 2030 (USD Million)
Table 6 UK Recombinant Protein Manufacturing Services Market by Service Type, 2018 - 2030 (USD Million)
Table 7 UK Recombinant Protein Manufacturing Services Market by Host Cell, 2018 - 2030 (USD Million)
Table 8 UK Recombinant Protein Manufacturing Services Market by End-use, 2018 - 2030 (USD Million)
Table 9 Germany Recombinant Protein Manufacturing Services Market by Service Type, 2018 - 2030 (USD Million)
Table 10 Germany Recombinant Protein Manufacturing Services Market by Host Cell, 2018 - 2030 (USD Million)
Table 11 Germany Recombinant Protein Manufacturing Services Market by End-use, 2018 - 2030 (USD Million)
Table 12 France Recombinant Protein Manufacturing Services Market by Service Type, 2018 - 2030 (USD Million)
Table 13 France Recombinant Protein Manufacturing Services Market by Host Cell, 2018 - 2030 (USD Million)
Table 14 France Recombinant Protein Manufacturing Services Market by End-use, 2018 - 2030 (USD Million)
Table 15 Italy Recombinant Protein Manufacturing Services Market by Service Type, 2018 - 2030 (USD Million)
Table 16 Italy Recombinant Protein Manufacturing Services Market by Host Cell, 2018 - 2030 (USD Million)
Table 17 Italy Recombinant Protein Manufacturing Services Market by End-use, 2018 - 2030 (USD Million)
Table 18 Spain Recombinant Protein Manufacturing Services Market by Service Type, 2018 - 2030 (USD Million)
Table 19 Spain Recombinant Protein Manufacturing Services Market by Host Cell, 2018 - 2030 (USD Million)
Table 20 Spain Recombinant Protein Manufacturing Services Market by End-use, 2018 - 2030 (USD Million)
Table 21 Denmark Recombinant Protein Manufacturing Services Market by Service Type, 2018 - 2030 (USD Million)
Table 22 Denmark Recombinant Protein Manufacturing Services Market by Host Cell, 2018 - 2030 (USD Million)
Table 23 Denmark Recombinant Protein Manufacturing Services Market by End-use, 2018 - 2030 (USD Million)
Table 24 Sweden Recombinant Protein Manufacturing Services Market by Service Type, 2018 - 2030 (USD Million)
Table 25 Sweden Recombinant Protein Manufacturing Services Market by Host Cell, 2018 - 2030 (USD Million)
Table 26 Sweden Recombinant Protein Manufacturing Services Market by End-use, 2018 - 2030 (USD Million)
Table 27 Norway Recombinant Protein Manufacturing Services Market by Service Type, 2018 - 2030 (USD Million)
Table 28 Norway Recombinant Protein Manufacturing Services Market by Host Cell, 2018 - 2030 (USD Million)
Table 29 Norway Recombinant Protein Manufacturing Services Market by End-use, 2018 - 2030 (USD Million)
Table 30 Switzerland Recombinant Protein Manufacturing Services Market by Service Type, 2018 - 2030 (USD Million)
Table 31 Switzerland Recombinant Protein Manufacturing Services Market by Host Cell, 2018 - 2030 (USD Million)
Table 32 Switzerland Recombinant Protein Manufacturing Services Market by End-use, 2018 - 2030 (USD Million)
Table 33 Netherlands Recombinant Protein Manufacturing Services Market by Service Type, 2018 - 2030 (USD Million)
Table 34 Netherlands Recombinant Protein Manufacturing Services Market by Host Cell, 2018 - 2030 (USD Million)
Table 35 Netherlands Recombinant Protein Manufacturing Services Market by End-use, 2018 - 2030 (USD Million)
Table 36 Participant’s overview
Table 37 Financial performance
Table 38 Key companies undergoing expansions
Table 39 Key companies undergoing acquisitions
Table 40 Key companies undergoing collaborations
Table 41 Key companies launching new products/services
Table 42 Key companies undergoing partnerships
Table 43 Key companies undertaking other strategies
List of Figures
Figure 1. Market research process
Figure 2. Data triangulation techniques
Figure 3. Primary research pattern
Figure 4. Market research approaches
Figure 5. Value-chain-based sizing & forecasting
Figure 6. QFD modeling for market share assessment
Figure 7. Market formulation & validation
Figure 8. Market summary, 2022 (USD Million)
Figure 9. Market segmentation & scope
Figure 10. Market driver impact
Figure 11. Market restraint impact
Figure 12. Penetration & growth prospect mapping
Figure 13. Porter’s analysis
Figure 14. SWOT analysis
Figure 15. Europe Recombinant Protein Manufacturing Services Market: Service type outlook and key takeaways
Figure 16. Europe Recombinant Protein Manufacturing Services Market: Service type movement analysis
Figure 17. Europe Pre-clinical & Clinical Services market, 2018 - 2030 (USD Million)
Figure 18. Europe Commercial Production Services market, 2018 - 2030 (USD Million)
Figure 19. Europe Recombinant Protein Manufacturing Services Market: Host cell outlook and key takeaways
Figure 20. Europe Recombinant Protein Manufacturing Services Market: Host cell movement analysis
Figure 21. Europe Mammalian Cells market, 2018 - 2030 (USD Million)
Figure 22. Europe Bacterial Cells market, 2018 - 2030 (USD Million)
Figure 23. Europe Insect Cells market, 2018 - 2030 (USD Million)
Figure 24. Europe Yeast & Fungi market, 2018 - 2030 (USD Million)
Figure 25. Europe Others Market, 2018 - 2030 (USD Million)
Figure 26. Europe Recombinant Protein Manufacturing Services Market: End-use outlook and key takeaways
Figure 27. Europe Recombinant Protein Manufacturing Services Market: End-use movement analysis
Figure 28. Europe Pharmaceutical & Biotechnology Companies Market, 2018 - 2030 (USD Million)
Figure 29. Europe Academic & Research Institutes market, 2018 - 2030 (USD Million)
Figure 30. Europe Recombinant Protein Manufacturing Services Market: Country outlook and key takeaways
Figure 31. Germany key country dynamics
Figure 32. Germany Recombinant Protein Manufacturing Services Market estimates and forecast, 2018 - 2030 (USD Million)
Figure 33. France key country dynamics
Figure 34. France Recombinant Protein Manufacturing Services Market estimates and forecast, 2018 - 2030 (USD Million)
Figure 35. UK key country dynamics
Figure 36. UK Recombinant Protein Manufacturing Services Market estimates and forecast, 2018 - 2030 (USD Million)
Figure 37. Italy key country dynamics
Figure 38. Italy Recombinant Protein Manufacturing Services Market estimates and forecast, 2018 - 2030 (USD Million)
Figure 39. Spain key country dynamics
Figure 40. Spain Recombinant Protein Manufacturing Services Market estimates and forecast, 2018 - 2030 (USD Million)
Figure 41. Denmark key country dynamics
Figure 42. Denmark Recombinant Protein Manufacturing Services Market estimates and forecast, 2018 - 2030 (USD Million)
Figure 43. Sweden key country dynamics
Figure 44. Sweden Recombinant Protein Manufacturing Services Market estimates and forecast, 2018 - 2030 (USD Million)
Figure 45. Norway key country dynamics
Figure 46. Norway Recombinant Protein Manufacturing Services Market estimates and forecast, 2018 - 2030 (USD Million)
Figure 47. Switzerland key country dynamics
Figure 48. Switzerland Recombinant Protein Manufacturing Services Market estimates and forecast, 2018 - 2030 (USD Million)
Figure 49. Netherlands key country dynamics
Figure 50. Netherlands Recombinant Protein Manufacturing Services Market estimates and forecast, 2018 - 2030 (USD Million)
Figure 51. Rest of Europe key country dynamics
Figure 52. Rest of Europe Recombinant Protein Manufacturing Services Market estimates and forecast, 2018 - 2030 (USD Million)
Figure 53. Market participant categorization
Figure 54. Europe Recombinant Protein Manufacturing Services Market share analysis, 2022
Figure 55. Strategy framework

Companies Mentioned

  • Lonza
  • Boehringer Ingelheim International GmbH
  • FUJIFILM Diosynth Biotechnologies
  • Merck KGaA
  • Bruker (InVivo BioTech Services GmbH)
  • Sino Biological, Inc.
  • GenScript
  • Kaneka corporation (Kaneka Eurogentec S.A)
  • Polyplus Transfection (Xpress Biologics)
  • Boster Biological Technology
  • Trenzyme GmbH

Methodology

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Table Information