The global optogenetics market was valued at $114.1 million in 2022, and is projected to reach $196.3 million by 2032, growing at a CAGR of 5.6% from 2023 to 2032. Optogenetics is a field of neuroscience that involves the use of light to control the activity of cells that have been genetically modified to be light-sensitive. It is a technique that uses genetically encoded light-sensitive proteins called opsins, to manipulate the activity of neurons in-vivo. These opsins act as ion channels that are activated by different wavelengths of light, enabling fast and targeted manipulation of neural activity. By selectively targeting opsin expression to specific cells, researchers can investigate the neural activity and pathological behaviors. Optogenetics has been primarily used in animal models, and could be applied in the development of new therapies for neurological and psychiatric disorders in humans.
The optogenetics market growth is driven by rise in development of advanced optogenetic tools such as genetically-encoded light-sensitive proteins, Increase in demand for neuroscience research, and rise in adoption of optogenetics in academic and research institutions. Optogenetics is a powerful tool for studying the brain and nervous system, therefore it is a used for neuroscience research and drives the market growth. For instance, researchers are developing new optogenetic implant for the treatment of patients suffering from multiple sclerosis. In addition, some of the preclinical studies have shown that optogenetic therapy can restore light sensitivity and improve visual function in animal suffering from inherited retinal dystrophies (IRD). Therefore, rise in demand for neuroscience research drives the growth of the market.
For instance, newly developed microbial opsins respond to different wavelengths of light, allowing researchers to target specific neurons with greater precision. Furthermore, development of novel opsins, laser sources, and imaging technologies to improve the effectiveness of optogenetic studies, further contribute toward the market growth.
In addition, development of highly efficient viral vectors for ocular gene therapy has led to new strategies for using optogenetic tools in vision restoration. Thus, advancement in optogenetic tools is driving the growth of the market. Moreover, Increase in research activities for treating retinal diseases by using optogenetic tools further contribute toward the market growth. For instance, single intravitreal injection of virally-carried Multi-Characteristic Opsin (MCO-010) for the treatment of retinitis pigmentosa is under phase-2 evaluation. Thus, rise in the clinical evaluations is expected to create lucrative growth opportunities for optogenetics.
Furthermore, rise in funding activities to conduct the preclinical and clinical evaluations of new optogenetic applications by various government institutes further contribute toward the market growth. For instance, Institute for Auditory Neuroscience received funding of $2.6 million for its Cochlear Optogenetics for Auditory Research from December 2015 to February 2022 by the European Commission. Therefore, such initiatives taken by the government supports the institutes to continue the research of optogenetics, which, in turn, boosts the market growth.
However, factors that hinder the market growth Include the high cost of laser sources and accessories. It further limits the adoption of optogenetics, which, in turn, restrains the market growth. For instance, Fabry-Perot Benchtop Laser Source, 405 nm, 8.0 mW, FC/PC offered by Thorlabs, Inc. costs about $1,900-$2,000. Thus, the high cost of laser sources negatively impact market growth.
On the other hand, Increase in awareness about the potentials of optogenetics among researchers and wide applications of optogenetics in neuroscience research and drug discovery are expected to create immense opportunities for the optogenetics market during the forecast period.
The optogenetics market is segmented on the basis of optogenetic tools, application, and region. On the basis of optogenetic tools, the market is classified into light equipment, actuators, and sensors. As per application, the market is segmented into neuroscience, retinal disorders, behavior tracking, and others (cardiac, kidney injury, diabetic research, and others). Region wise, the market is analyzed across North America (the U.S., Canada, and Mexico), Europe (Germany, France, the UK, Italy, Spain, and rest of Europe), Asia-Pacific (China, Japan, Australia, India, South Korea, and rest of Asia-Pacific), and LAMEA (Brazil, South Africa, Saudi Arabia, and rest of LAMEA).
Major key players that operate in the global optogenetics market are Bruker Corporation, Coherent, Inc., Elliot Scientific Ltd., GenSight Biologics, Laserglow Technologies, Mightex, Prizmatix, Profacgen, Shanghai Laser & Optics Century Co., Ltd., and Thorlabs Inc.
The optogenetics market growth is driven by rise in development of advanced optogenetic tools such as genetically-encoded light-sensitive proteins, Increase in demand for neuroscience research, and rise in adoption of optogenetics in academic and research institutions. Optogenetics is a powerful tool for studying the brain and nervous system, therefore it is a used for neuroscience research and drives the market growth. For instance, researchers are developing new optogenetic implant for the treatment of patients suffering from multiple sclerosis. In addition, some of the preclinical studies have shown that optogenetic therapy can restore light sensitivity and improve visual function in animal suffering from inherited retinal dystrophies (IRD). Therefore, rise in demand for neuroscience research drives the growth of the market.
For instance, newly developed microbial opsins respond to different wavelengths of light, allowing researchers to target specific neurons with greater precision. Furthermore, development of novel opsins, laser sources, and imaging technologies to improve the effectiveness of optogenetic studies, further contribute toward the market growth.
In addition, development of highly efficient viral vectors for ocular gene therapy has led to new strategies for using optogenetic tools in vision restoration. Thus, advancement in optogenetic tools is driving the growth of the market. Moreover, Increase in research activities for treating retinal diseases by using optogenetic tools further contribute toward the market growth. For instance, single intravitreal injection of virally-carried Multi-Characteristic Opsin (MCO-010) for the treatment of retinitis pigmentosa is under phase-2 evaluation. Thus, rise in the clinical evaluations is expected to create lucrative growth opportunities for optogenetics.
Furthermore, rise in funding activities to conduct the preclinical and clinical evaluations of new optogenetic applications by various government institutes further contribute toward the market growth. For instance, Institute for Auditory Neuroscience received funding of $2.6 million for its Cochlear Optogenetics for Auditory Research from December 2015 to February 2022 by the European Commission. Therefore, such initiatives taken by the government supports the institutes to continue the research of optogenetics, which, in turn, boosts the market growth.
However, factors that hinder the market growth Include the high cost of laser sources and accessories. It further limits the adoption of optogenetics, which, in turn, restrains the market growth. For instance, Fabry-Perot Benchtop Laser Source, 405 nm, 8.0 mW, FC/PC offered by Thorlabs, Inc. costs about $1,900-$2,000. Thus, the high cost of laser sources negatively impact market growth.
On the other hand, Increase in awareness about the potentials of optogenetics among researchers and wide applications of optogenetics in neuroscience research and drug discovery are expected to create immense opportunities for the optogenetics market during the forecast period.
The optogenetics market is segmented on the basis of optogenetic tools, application, and region. On the basis of optogenetic tools, the market is classified into light equipment, actuators, and sensors. As per application, the market is segmented into neuroscience, retinal disorders, behavior tracking, and others (cardiac, kidney injury, diabetic research, and others). Region wise, the market is analyzed across North America (the U.S., Canada, and Mexico), Europe (Germany, France, the UK, Italy, Spain, and rest of Europe), Asia-Pacific (China, Japan, Australia, India, South Korea, and rest of Asia-Pacific), and LAMEA (Brazil, South Africa, Saudi Arabia, and rest of LAMEA).
Major key players that operate in the global optogenetics market are Bruker Corporation, Coherent, Inc., Elliot Scientific Ltd., GenSight Biologics, Laserglow Technologies, Mightex, Prizmatix, Profacgen, Shanghai Laser & Optics Century Co., Ltd., and Thorlabs Inc.
Key Benefits For Stakeholders
- This report provides a quantitative analysis of the market segments, current trends, estimations, and dynamics of the optogenetics market analysis from 2022 to 2032 to identify the prevailing optogenetics market opportunities.
- The market research is offered along with information related to key drivers, restraints, and opportunities.
- Porter's five forces analysis highlights the potency of buyers and suppliers to enable stakeholders make profit-oriented business decisions and strengthen their supplier-buyer network.
- In-depth analysis of the optogenetics market segmentation assists to determine the prevailing market opportunities.
- Major countries in each region are mapped according to their revenue contribution to the global market.
- Market player positioning facilitates benchmarking and provides a clear understanding of the present position of the market players.
- The report Includes the analysis of the regional as well as global optogenetics market trends, key players, market segments, application areas, and market growth strategies.
Key Market Segments
By Optogenetic tools
- Light Equipment
- Type
- LED
- LASER
- Actuators
- Sensors
By Application
- Neuroscience
- Retinal disorder
- Behaviour tracking
- Others
By Region
- North America
- U.S.
- Canada
- Mexico
- Europe
- Germany
- France
- UK
- Italy
- Spain
- Rest of Europe
- Asia-Pacific
- Japan
- China
- Australia
- India
- South Korea
- Rest of Asia-Pacific
- LAMEA
- Brazil
- Saudi Arabia
- South Africa
- Rest of LAMEA
Key Market Players
- Mightex
- Prizmatix
- Laserglow Technologies
- Thorlabs Inc.
- GenSight Biologics
- Elliot Scientific Ltd.
- Profacgen
- Shanghai Laser & Optics Century Co., Ltd.
- Coherent, Inc.
- Bruker Corporation
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Table of Contents
CHAPTER 1: INTRODUCTION
CHAPTER 2: EXECUTIVE SUMMARY
CHAPTER 3: MARKET OVERVIEW
CHAPTER 4: OPTOGENETICS MARKET, BY OPTOGENETIC TOOLS
CHAPTER 5: OPTOGENETICS MARKET, BY APPLICATION
CHAPTER 6: OPTOGENETICS MARKET, BY REGION
CHAPTER 7: COMPETITIVE LANDSCAPE
CHAPTER 8: COMPANY PROFILES
List of Tables
List of Figures
Executive Summary
According to a new report, titled, 'Optogenetics Market,' The optogenetics market was valued at $114.1 million in 2022, and is estimated to reach $196.3 million by 2032, growing at a CAGR of 5.6% from 2023 to 2032. Optogenetics is a field of neuroscience that utilizes genetically modified light-sensitive cells and proteins called opsins to control neural activity using light. Opsins act as ion channels and can be activated by specific wavelengths of light, allowing precise and rapid manipulation of neurons. By selectively expressing opsins in targeted cells, researchers can study neural activity and behaviors. Optogenetics is used in animal models and can be used in development of new therapies for psychiatric and neurological disorders. It is a powerful tool that enables researchers to gain a deeper understanding of the complexities of the brain.Key factors driving the growth of the optogenetics market include increase in neuroscience research, and development of advanced optogeentic tools. Optogenetics offers a powerful technique for manipulating and observing the activity of specific neurons in the brain, making it a valuable tool in numerous neuroscience studies. For instance, Nanoscope Therapeutics, Inc., a biotechnology research company is conducting phase-2 studies on a virally-carried Multi-Characteristic Opsin (vMCO-010) administered through intravitreal injection for the treatment of Stargardt disease, an inherited eye disorder. This highlights the potential of optogenetics in developing innovative treatments for various conditions. In addition, rise in number of researchers investigating neurological disorders and brain development has also contributed to the rising demand for optogenetic tools and techniques. Furthermore, development of technologically advanced optogenetic tools also contribute towards the market growth. Researchers have developed miniaturized and wireless implantable devices that can deliver light to targeted areas of the brain with high precision. These devices offer greater flexibility and ease of use in optogenetic experiments. For instance, a study published in Nature Methods demonstrated the development of an ultra-miniaturized wireless optoelectronic device capable of stimulating and recording neural activity in freely behaving animals. In addition, development of new opsins with increased light sensitivity, improved kinetics, and expanded spectral properties enable more precise and versatile control of neural activity. Such technological advancements in optogenetics contribute to improving the precision, flexibility, and applicability of the technique which, in turn, boost the market growth.
Advancements in genetic engineering techniques, such as the development of more efficient methods like CRISPR-Cas9, have revolutionized optogenetics research. These techniques allow researchers to precisely and rapidly engineer cells with light-sensitive proteins. These cells enhances the precision and speed of optogenetic experiments. Furthermore, optogenetics tools like fiber optic cables, LEDs, and advanced microscopes have also become more precise and efficient which propels the market growth. Actuators are genetically-encoded tools that allow researchers to control the activity of proteins using light. These tools include microbial opsins and optical switches, which can be inserted into cells or organisms to provide precise control over protein activity. The increase in use of optogenetics in neuroscience and other fields has driven demand for actuators for controlling the activity of cells using light. Surge in development of modified actuators for use in optogenetic experiments further boost the market growth. Furthermore, development of advanced actuators such as ChrimsonR, OptoSTIM1, and Jaws further propels the market growth. Moreover, increase in availability of optogenetic equipment also propels the market growth.
Moreover, continued advancements in optogenetics technology, including the development of light sensitive proteins, broad spectrum LEDs and increase in awareness among researchers about potentials of otogenetics are expected to create lucrative opportunities for the market growth during the forecast period. The application of optogenetics in the treatment of epilepsy, Parkinson's disease, depression, and anxiety holds great promise and presents lucrative opportunities for market growth.
The optogenetics market is segmented on the basis of optogenetic tools, application, and region. On the basis of optogenetic tools, the market is classified into light equipment, actuators, and sensors. As per application, the market is segmented into neuroscience, retinal disorders, behavior tracking, and others. Others segment include cardiac, kidney injury, diabetic research, and others. On the basis of region, the market is analyzed across North America (the U.S., Canada, and Mexico), Europe (Germany, France, UK, Italy, Spain, and Rest of Europe), Asia-Pacific (Japan, China, Australia, India, South Korea, and Rest of Asia-Pacific), and LAMEA (Brazil, South Africa, Saudi Arabia, and rest of LAMEA).
The key players profiled in the study include Bruker Corporation, Coherent, Inc., Elliot Scientific Ltd., GenSight Biologics, Laserglow Technologies, Mightex, Prizmatix, Profacgen, Shanghai Laser & Optics Century Co., Ltd., and Thorlabs Inc.
Key Market Insights
- By optogenetic tools, the actuators segment was the highest revenue contributor to the market in 2022 and is estimated to reach $97,989.1 million by 2032.
- By application, the retinal disorders segment dominated the global market in 2022.
- Based on region, North America garnered the largest revenue share in 2022. However Asia-Pacific is anticipated to grow at the highest CAGR of 6.7% during the forecast period.
Companies Mentioned
- Mightex
- Prizmatix
- Laserglow Technologies
- Thorlabs Inc.
- GenSight Biologics
- Elliot Scientific Ltd.
- Profacgen
- Shanghai Laser & Optics Century Co., Ltd.
- Coherent, Inc.
- Bruker Corporation
Methodology
The analyst offers exhaustive research and analysis based on a wide variety of factual inputs, which largely include interviews with industry participants, reliable statistics, and regional intelligence. The in-house industry experts play an instrumental role in designing analytic tools and models, tailored to the requirements of a particular industry segment. The primary research efforts include reaching out participants through mail, tele-conversations, referrals, professional networks, and face-to-face interactions.
They are also in professional corporate relations with various companies that allow them greater flexibility for reaching out to industry participants and commentators for interviews and discussions.
They also refer to a broad array of industry sources for their secondary research, which typically include; however, not limited to:
- Company SEC filings, annual reports, company websites, broker & financial reports, and investor presentations for competitive scenario and shape of the industry
- Scientific and technical writings for product information and related preemptions
- Regional government and statistical databases for macro analysis
- Authentic news articles and other related releases for market evaluation
- Internal and external proprietary databases, key market indicators, and relevant press releases for market estimates and forecast
Furthermore, the accuracy of the data will be analyzed and validated by conducting additional primaries with various industry experts and KOLs. They also provide robust post-sales support to clients.
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Table Information
| Report Attribute | Details |
|---|---|
| No. of Pages | 216 |
| Published | May 2023 |
| Forecast Period | 2022 - 2032 |
| Estimated Market Value ( USD | $ 114.1 million |
| Forecasted Market Value ( USD | $ 196.3 million |
| Compound Annual Growth Rate | 5.6% |
| Regions Covered | Global |
| No. of Companies Mentioned | 10 |
