Sustainable Approaches in Pharmaceutical Sciences enables readers to understand the best possible green approaches associated with the development, design, and origination of pharmaceuticals, including resources that may minimize the adverse effects associated with synthesis, isolation, and extraction.
Sustainable Approaches in Pharmaceutical Sciences covers a myriad of current topics, including mechanochemical improvements for API synthesis, as well as the role of artificial intelligence (AI) in the development and discovery of pharmaceuticals, along with recent developments in hydrogels which respond to triggered factors during topical drug delivery. Authored by experienced scientists from institutions across the world, other sample topics covered in Sustainable Approaches in Pharmaceutical Sciences include: - Green technologies and benefits associated with them, white biotechnology, green chemistry, and eco-friendly approaches for designing active pharmaceutical ingredients - Impact of sustainable approaches in pharmaceutical industries regarding use of solvents, nanoparticles formulations, and antimicrobial bandages - Micro-extractive methods capable of generating high recovery values of the analytes and associated techniques, such as dispersive liquid-liquid microextraction - Benefits of the exploration of sustainable chemistry on a commercial scale, particularly in relation to bioresources, chemical manufacturing, and organic transformation
Discussing both the foundational science and practicality of different approaches regarding human and environmental health, Sustainable Approaches in Pharmaceutical Sciences is an essential resource for scientists, medical professionals, and industrial professionals working in the fields of sustainable technology and synthesis in pharmaceutical sciences, along with advanced level students.
Table of Contents
List of Contributors vi
Preface x
1 Green and Sustainable Approaches in Pharmaceutical Sciences 1
Shiv Bahadur, Radhika, Durgesh Nandini Chauhan, Nagendra Singh Chauhan and Kamal Shah
2 Green Approaches in Conventional Drug Synthesis 17
Hassan Rafique, Nazim Hussain, Muhammad Usama Saeed and Muhammad Bilal
3 Modern Green Extraction Techniques 35
Marcello Locatelli, Enrica Rosato, Cristian D’Ovidio, Martina Bonelli, Halil Ibrahim Ulusoy, Abuzar Kabir, Imran Ali, Fabio Savini, Ugo de Grazia, Victoria Samanidou and Angela Tartaglia
4 Impact of Green Approaches in Pharmaceutical Industries 65
Taruna Grover, Rishita J. Chauhan, Anuradha K. Gajjar, Tejas M. Dhameliya and Maulikkumar D. Vaja
5 Green Analytical Techniques Using Hydrotropy, Mixed Hydrotropy, and Mixed Solvency 91
Atish S. Mundada, Deepak D. Patil and Rajesh K. Maheshwari
6 Application of Artificial Intelligence in Drug Design and Development 113
Somdutt Mujwar and Kamal Shah
7 Green Chemistry in the Development of Functionalised Hydrogels as Topical Drug-Delivery Systems 121
Maha Mohammad AL-Rajabi and Teow Yeit Haan
8 Advanced Approaches in Green Univariate Spectrophotometric Methods 157
Hayam M. Lotfy, Sarah S. Saleh, Yasmin Rostom, Reem H. Obaydo and Dina A. Ahmed
9 Cyclodextrin-Based Molecular Inclusion by Grinding: Quality by Design in Green Chemistry 217
Sanyam Sharma, Subh Naman and Ashish Baldi
10 Synthesis of Graphitic Carbon Nitride Quantum Dots from Bulk Graphitic Carbon Nitride 237
Joseph Selvin, Jegam Noel Joseph and Selvaraj Mohana Roopan
11 Mechanochemistry for Sustainable Drug Design and Active Pharmaceutical Ingredient Synthesis 255
Pedro Brandão and Marta Pineiro
Index 273
