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Small Molecule API Market Analysis & Forecast 2024-2034: Market By Type; By Manufacturer; By Application; and By Region

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    Report

  • 145 Pages
  • October 2023
  • Region: Global
  • Erevna Healthcare
  • ID: 5890352
The global small molecule API market size was estimated to be USD 157.33 billion in 2023 and is expected to reach at USD 329.12 billion by 2034 with a CAGR of 6.94% during the forecast period 2024-2034. Increasing demand for small molecule drugs, rise in outsourcing & the patent expirations of key compounds, growing prevalence of chronic diseases, surge in research & development activities, increasing launch of novel products, rising use of novel technologies, growing collaboration within market players for the discovery of small molecules using AI-based technology, and surge in approvals by regulatory bodies, are some of the leading factors fuelling the market growth.

Surge in approvals of targeted therapies by regulatory bodies is predicted to boost the market growth during the forecast period. The growing occurrence of chronic illnesses worldwide has prompted pharmaceutical makers to develop a greater number of therapeutic drugs. For instance, in December 2022, The U.S. FDA has granted KRAZATI (adagrasib) expedited approval as a targeted treatment option for adult patients with KRAS mutations and locally advanced or metastatic non-small cell lung cancer. This information was released by Mirati Therapeutics, Inc.

By type, synthetic was the highest revenue-grossing segment in the global small molecule API market in 2023 owing to the low cost of making these compounds and their remarkable efficacy, rising prevalence of synthetic pharmaceuticals in the pharmaceutical sector, which drives demand for production-related raw materials such small molecule APIs, presence of major market players. Additionally, biotech is predicted to grow at fastest CAGR during the forecast period owing to the growing number of firms are looking for backward integration & creating new factories to boost productivity, increasing focus on targeted therapies, rising demand for biotech-based products, and growing investment by major market players. For instance, in April 2022, AVM biotechnology has initiated a study involving its small molecule, AVM0703, for the purpose of reversing Type 1 diabetes. This effort has been facilitated by the reception of a Phase II Small Business Innovation Research (SBIR) award amounting to USD 1.6 million from the National Institute of Diabetes and Digestive Kidney Disease (NIDDK).

By manufacturer, in-house was the highest revenue-grossing segment in the global small molecule API market in 2023 owing to a large number of businesses manufacture their own API, reducing their reliance on raw material sources and rising investment by key market players. For instance, in September 2022, Cambrex has finished the initial stage of its $30 million investment in its manufacturing facility for small molecule active pharmaceutical ingredients located in High Point, North Carolina. Additionally, outsourcing is predicted to grow at fastest CAGR during the forecast period owing to the surge in numerous compounds that need sophisticated production procedures are being authorized, major firms have improved their capabilities to fulfil market needs as the CDMO business has experienced significant mobility.

By application, cardiology was the highest revenue-grossing segment in the global small molecule API market in 2023 owing to rising prevalence of cardiovascular conditions, surge in adoption of sedentary lifestyle & food habits, and growing product approvals by regulatory bodies. Additionally, oncology is predicted to grow at fastest CAGR during the forecast period owing to the growing prevalence of cancer, rising demand for cancer drugs, and increasing partnerships & collaborations within market players. For instance, in June 2022, Dr. Reddy's Laboratories Ltd. has reported that one of its subsidiaries has entered into a collaboration with Olema Pharmaceuticals, a U.S.-based company. This collaboration involves joint efforts in researching, developing, and marketing new small molecule inhibitors targeting an undisclosed oncology objective.

North America region is anticipated for the highest revenue share during the forecast period owing to the rising government initiatives, growing demand for small molecules, increasing focus on expansion by key market players, and surge in collaborations within market players. For instance, in January 2022, Pfizer Inc. and Biohaven have finalized a collaborative transaction aimed at marketing small molecule migraine medications, specifically rimegepant and zavegepant, in regions beyond the United States. Additionally, Asia Pacific region is predicted to grow at fastest CAGR during the forecast period owing to the growing healthcare infrastructure, the presence of major manufacturers, rising government support for investing in API business, and increasing initiatives by leading market players. For instance, in March 2022, Lonza has announced that the expansion project for the laboratory housed within its active pharmaceutical ingredient (API) production plant in China has been completed successfully. This expansion has enabled the company to concentrate on producing high potency APIs for small molecules.

Segmentation: Small Molecule API Market Report 2022 - 2033

Small Molecule API Market Analysis & Forecast by Type 2023 - 2034 (Revenue USD Bn)

  • Biotech
  • Synthetic

Small Molecule API Market Analysis & Forecast by Manufacturer 2023 - 2034 (Revenue USD Bn)

  • Outsourced
  • In-house

Small Molecule API Market Analysis & Forecast by Application 2023 - 2034 (Revenue USD Bn)

  • Nephrology
  • Gastroenterology
  • Cardiology
  • Pulmonology
  • Orthopedic
  • Oncology
  • Ophthalmology
  • Endocrinology
  • CNS and Neurology
  • Others

Small Molecule API Market Analysis & Forecast by Region 2023 - 2034 (Revenue USD Bn)

North America

  • U.S.
  • Canada

Europe

  • Germany
  • France
  • UK
  • Spain
  • Italy
  • Rest of Europe

Asia Pacific

  • China
  • Japan
  • India
  • Australia
  • South Korea
  • Rest of APAC

Latin America

  • Brazil
  • Mexico
  • Argentina
  • Rest of LATAM

Middle East & Africa

  • South Africa
  • GCC
  • Rest of MEA

Table of Contents

1. Research Methodology
1.1. Study Objectives
1.2. Study Scope
1.3. Research Assumptions
1.4. Research Framework
2. Introduction
2.1. Market Definition
2.2. Global Small Molecule API Market Overview
3. Executive Summary
4. Market Environment Analysis
4.1. Porter’s 5 Forces Analysis
4.2. PESTEL Analysis
4.3. SWOT Analysis
5. Market Dynamics
5.1. Drivers Analysis
5.2. Restraints Analysis
5.3. Opportunities Analysis
5.4. Threats Analysis
5.5. Trend Analysis
6. COVID-19 Impact Analysis
7. Small Molecule API Market: Type Estimates & Trend Analysis
7.1. Type Segment Opportunity Analysis
7.2. Biotech
7.2.1. Biotech Market Analysis & Forecast, 2023-2034 (Revenue, USD Bn)
7.3. Synthetic
7.3.1. Synthetic Market Analysis & Forecast, 2023-2034 (Revenue, USD Bn)
8. Small Molecule API Market: Manufacturer Estimates & Trend Analysis
8.1. Manufacturer Segment Opportunity Analysis
8.2. Outsourced
8.2.1. Outsourced Market Analysis & Forecast, 2023-2034 (Revenue, USD Bn)
8.3. In-house
8.3.1. In-house Market Analysis & Forecast, 2023-2034 (Revenue, USD Bn)
9. Small Molecule API Market: Application Estimates & Trend Analysis
9.1. Application Segment Opportunity Analysis
9.2. Nephrology
9.2.1. Nephrology Market Analysis & Forecast, 2023-2034 (Revenue, USD Bn)
9.3. Gastroenterology
9.3.1. Gastroenterology Market Analysis & Forecast, 2023-2034 (Revenue, USD Bn)
9.4. Cardiology
9.4.1. Cardiology Market Analysis & Forecast, 2023-2034 (Revenue, USD Bn)
9.5. Pulmonology
9.5.1. Pulmonology Market Analysis & Forecast, 2023-2034 (Revenue, USD Bn)
9.6. Orthopedic
9.6.1. Orthopedic Market Analysis & Forecast, 2023-2034 (Revenue, USD Bn)
9.7. Oncology
9.7.1. Oncology Market Analysis & Forecast, 2023-2034 (Revenue, USD Bn)
9.8. Ophthalmology
9.8.1. Ophthalmology Market Analysis & Forecast, 2023-2034 (Revenue, USD Bn)
9.9. Endocrinology
9.9.1. Endocrinology Market Analysis & Forecast, 2023-2034 (Revenue, USD Bn)
9.10. CNS and Neurology
9.10.1. CNS and Neurology Market Analysis & Forecast, 2023-2034 (Revenue, USD Bn)
9.11. Others
9.11.1. Others Market Analysis & Forecast, 2023-2034 (Revenue, USD Bn)
10. Regional Market Analysis
10.1. Regional Market Opportunity Analysis
11. North America Small Molecule API Market
11.1. North America Small Molecule API Market
11.1.1. North America Small Molecule API Market Size and Forecast, 2023-2034 (Revenue USD Bn)
11.1.2. North America Small Molecule API Market Size and Forecast, By Country, 2023-2034 (Revenue USD Bn)
11.1.3. North America Small Molecule API Market Size and Forecast, By Type, 2023-2034 (Revenue USD Bn)
11.1.4. North America Small Molecule API Market Size and Forecast, By Manufacturer, 2023-2034 (Revenue USD Bn)
11.1.5. North America Small Molecule API Market Size and Forecast, By Application, 2023-2034 (Revenue USD Bn)
11.2. U.S. Global Small Molecule API Market
11.2.1. U.S. Small Molecule API Market Size and Forecast, 2023-2034 (Revenue USD Bn)
11.2.2. U.S. Small Molecule API Market Size and Forecast, By Type, 2023-2034 (Revenue USD Bn)
11.2.3. U.S. Small Molecule API Market Size and Forecast, By Manufacturer, 2023-2034 (Revenue USD Bn)
11.2.4. U.S. Small Molecule API Market Size and Forecast, By Application, 2023-2034 (Revenue USD Bn)
11.3. Canada Global Small Molecule API Market
11.3.1. Canada Small Molecule API Market Size and Forecast, 2023-2034 (Revenue USD Bn)
11.3.2. Canada Small Molecule API Market Size and Forecast, By Type, 2023-2034 (Revenue USD Bn)
11.3.3. Canada Small Molecule API Market Size and Forecast, By Manufacturer, 2023-2034 (Revenue USD Bn)
11.3.4. Canada Small Molecule API Market Size and Forecast, By Application, 2023-2034 (Revenue USD Bn)
12. Europe Global Small Molecule API Market
12.1. Europe Global Small Molecule API Market
12.1.1. Europe Small Molecule API Market Size and Forecast, 2023-2034 (Revenue USD Bn)
12.1.2. Europe Small Molecule API Market Size and Forecast, By Country, 2023-2034 (Revenue USD Bn)
12.1.3. Europe Small Molecule API Market Size and Forecast, By Type, 2023-2034 (Revenue USD Bn)
12.1.4. Europe Small Molecule API Market Size and Forecast, By Manufacturer, 2023-2034 (Revenue USD Bn)
12.1.5. Europe Small Molecule API Market Size and Forecast, By Application, 2023-2034 (Revenue USD Bn)
12.2. Germany Global Small Molecule API Market
12.2.1. Germany Small Molecule API Market Size and Forecast, 2023-2034 (Revenue USD Bn)
12.2.2. Germany Small Molecule API Market Size and Forecast, By Type, 2023-2034 (Revenue USD Bn)
12.2.3. Germany Small Molecule API Market Size and Forecast, By Manufacturer, 2023-2034 (Revenue USD Bn)
12.2.4. Germany Small Molecule API Market Size and Forecast, By Application, 2023-2034 (Revenue USD Bn)
12.3. UK Global Small Molecule API Market
12.3.1. UK Small Molecule API Market Size and Forecast, 2023-2034 (Revenue USD Bn)
12.3.2. UK Small Molecule API Market Size and Forecast, By Type, 2023-2034 (Revenue USD Bn)
12.3.3. UK Small Molecule API Market Size and Forecast, By Manufacturer, 2023-2034 (Revenue USD Bn)
12.3.4. UK Small Molecule API Market Size and Forecast, By Application, 2023-2034 (Revenue USD Bn)
12.4. France Global Small Molecule API Market
12.4.1. France Small Molecule API Market Size and Forecast, 2023-2034 (Revenue USD Bn)
12.4.2. France Small Molecule API Market Size and Forecast, By Type, 2023-2034 (Revenue USD Bn)
12.4.3. France Small Molecule API Market Size and Forecast, By Manufacturer, 2023-2034 (Revenue USD Bn)
12.4.4. France Small Molecule API Market Size and Forecast, By Application, 2023-2034 (Revenue USD Bn)
12.5. Spain Global Small Molecule API Market
12.5.1. Spain Small Molecule API Market Size and Forecast, 2023-2034 (Revenue USD Bn)
12.5.2. Spain Small Molecule API Market Size and Forecast, By Type, 2023-2034 (Revenue USD Bn)
12.5.3. Spain Small Molecule API Market Size and Forecast, By Manufacturer, 2023-2034 (Revenue USD Bn)
12.5.4. Spain Small Molecule API Market Size and Forecast, By Application, 2023-2034 (Revenue USD Bn)
12.6. Italy Global Small Molecule API Market
12.6.1. Italy Small Molecule API Market Size and Forecast, 2023-2034 (Revenue USD Bn)
12.6.2. Italy Small Molecule API Market Size and Forecast, By Type, 2023-2034 (Revenue USD Bn)
12.6.3. Italy Small Molecule API Market Size and Forecast, By Manufacturer, 2023-2034 (Revenue USD Bn)
12.6.4. Italy Small Molecule API Market Size and Forecast, By Application, 2023-2034 (Revenue USD Bn)
12.7. Rest of Europe Global Small Molecule API Market
12.7.1. Rest of Europe Small Molecule API Market Size and Forecast, 2023-2034 (Revenue USD Bn)
12.7.2. Rest of Europe Small Molecule API Market Size and Forecast, By Type, 2023-2034 (Revenue USD Bn)
12.7.3. Rest of Europe Small Molecule API Market Size and Forecast, By Manufacturer, 2023-2034 (Revenue USD Bn)
12.7.4. Rest of Europe Small Molecule API Market Size and Forecast, By Application, 2023-2034 (Revenue USD Bn)
13. Asia Pacific Global Small Molecule API Market
13.1. Asia Pacific Global Small Molecule API Market
13.1.1. Asia Pacific Small Molecule API Market Size and Forecast, 2023-2034 (Revenue USD Bn)
13.1.2. Asia Pacific Small Molecule API Market Size and Forecast, By Country, 2023-2034 (Revenue USD Bn)
13.1.3. Asia Pacific Small Molecule API Market Size and Forecast, By Type, 2023-2034 (Revenue USD Bn)
13.1.4. Asia Pacific Small Molecule API Market Size and Forecast, By Manufacturer, 2023-2034 (Revenue USD Bn)
13.1.5. Asia Pacific Small Molecule API Market Size and Forecast, By Application, 2023-2034 (Revenue USD Bn)
13.2. Japan Global Small Molecule API Market
13.2.1. Japan Small Molecule API Market Size and Forecast, 2023-2034 (Revenue USD Bn)
13.2.2. Japan Small Molecule API Market Size and Forecast, By Type, 2023-2034 (Revenue USD Bn)
13.2.3. Japan Small Molecule API Market Size and Forecast, By Manufacturer, 2023-2034 (Revenue USD Bn)
13.2.4. Japan Small Molecule API Market Size and Forecast, By Application, 2023-2034 (Revenue USD Bn)
13.3. China Global Small Molecule API Market
13.3.1. China Small Molecule API Market Size and Forecast, 2023-2034 (Revenue USD Bn)
13.3.2. China Small Molecule API Market Size and Forecast, By Type, 2023-2034 (Revenue USD Bn)
13.3.3. China Small Molecule API Market Size and Forecast, By Manufacturer, 2023-2034 (Revenue USD Bn)
13.3.4. China Small Molecule API Market Size and Forecast, By Application, 2023-2034 (Revenue USD Bn)
13.4. India Global Small Molecule API Market
13.4.1. India Small Molecule API Market Size and Forecast, 2023-2034 (Revenue USD Bn)
13.4.2. India Small Molecule API Market Size and Forecast, By Type, 2023-2034 (Revenue USD Bn)
13.4.3. India Small Molecule API Market Size and Forecast, By Manufacturer, 2023-2034 (Revenue USD Bn)
13.4.4. India Small Molecule API Market Size and Forecast, By Application, 2023-2034 (Revenue USD Bn)
13.5. South Korea Global Small Molecule API Market
13.5.1. South Korea Small Molecule API Market Size and Forecast, 2023-2034 (Revenue USD Bn)
13.5.2. South Korea Small Molecule API Market Size and Forecast, By Type, 2023-2034 (Revenue USD Bn)
13.5.3. South Korea Small Molecule API Market Size and Forecast, By Manufacturer, 2023-2034 (Revenue USD Bn)
13.5.4. South Korea Small Molecule API Market Size and Forecast, By Application, 2023-2034 (Revenue USD Bn)
13.6. Australia Global Small Molecule API Market
13.6.1. Australia Small Molecule API Market Size and Forecast, 2023-2034 (Revenue USD Bn)
13.6.2. Australia Small Molecule API Market Size and Forecast, By Type, 2023-2034 (Revenue USD Bn)
13.6.3. Australia Small Molecule API Market Size and Forecast, By Manufacturer, 2023-2034 (Revenue USD Bn)
13.6.4. Australia Small Molecule API Market Size and Forecast, By Application, 2023-2034 (Revenue USD Bn)
13.7. Rest of Asia Pacific Global Small Molecule API Market
13.7.1. Rest of Asia Pacific Small Molecule API Market Size and Forecast, 2023-2034 (Revenue USD Bn)
13.7.2. Rest of Asia Pacific Small Molecule API Market Size and Forecast, By Type, 2023-2034 (Revenue USD Bn)
13.7.3. Rest of Asia Pacific Small Molecule API Market Size and Forecast, By Manufacturer, 2023-2034 (Revenue USD Bn)
13.7.4. Rest of Asia Pacific Small Molecule API Market Size and Forecast, By Application, 2023-2034 (Revenue USD Bn)
14. Latin America Global Small Molecule API Market
14.1. Latin America Global Small Molecule API Market
14.1.1. Latin America Small Molecule API Market Size and Forecast, 2023-2034 (Revenue USD Bn)
14.1.2. Latin America Small Molecule API Market Size and Forecast, By Country, 2023-2034 (Revenue USD Bn)
14.1.3. Latin America Small Molecule API Market Size and Forecast, By Type, 2023-2034 (Revenue USD Bn)
14.1.4. Latin America Small Molecule API Market Size and Forecast, By Manufacturer, 2023-2034 (Revenue USD Bn)
14.1.5. Latin America Small Molecule API Market Size and Forecast, By Application, 2023-2034 (Revenue USD Bn)
14.2. Brazil Global Small Molecule API Market
14.2.1. Brazil Small Molecule API Market Size and Forecast, 2023-2034 (Revenue USD Bn)
14.2.2. Brazil Small Molecule API Market Size and Forecast, By Type, 2023-2034 (Revenue USD Bn)
14.2.3. Brazil Small Molecule API Market Size and Forecast, By Manufacturer, 2023-2034 (Revenue USD Bn)
14.2.4. Brazil Small Molecule API Market Size and Forecast, By Application, 2023-2034 (Revenue USD Bn)
14.3. Mexico Global Small Molecule API Market
14.3.1. Mexico Small Molecule API Market Size and Forecast, 2023-2034 (Revenue USD Bn)
14.3.2. Mexico Small Molecule API Market Size and Forecast, By Type, 2023-2034 (Revenue USD Bn)
14.3.3. Mexico Small Molecule API Market Size and Forecast, By Manufacturer, 2023-2034 (Revenue USD Bn)
14.3.4. Mexico Small Molecule API Market Size and Forecast, By Application, 2023-2034 (Revenue USD Bn)
14.4. Argentina Global Small Molecule API Market
14.4.1. Argentina Small Molecule API Market Size and Forecast, 2023-2034 (Revenue USD Bn)
14.4.2. Argentina Small Molecule API Market Size and Forecast, By Type, 2023-2034 (Revenue USD Bn)
14.4.3. Argentina Small Molecule API Market Size and Forecast, By Manufacturer, 2023-2034 (Revenue USD Bn)
14.4.4. Argentina Small Molecule API Market Size and Forecast, By Application, 2023-2034 (Revenue USD Bn)
14.5. Rest of Latin America Global Small Molecule API Market
14.5.1. Rest of Latin America Small Molecule API Market Size and Forecast, 2023-2034 (Revenue USD Bn)
14.5.2. Rest of Latin America Small Molecule API Market Size and Forecast, By Type, 2023-2034 (Revenue USD Bn)
14.5.3. Rest of Latin America Small Molecule API Market Size and Forecast, By Manufacturer, 2023-2034 (Revenue USD Bn)
14.5.4. Rest of Latin America Small Molecule API Market Size and Forecast, By Application, 2023-2034 (Revenue USD Bn)
15. MEA Global Small Molecule API Market
15.1. MEA Global Small Molecule API Market
15.1.1. MEA Small Molecule API Market Size and Forecast, 2023-2034 (Revenue USD Bn)
15.1.2. MEA Small Molecule API Market Size and Forecast, By Country, 2023-2034 (Revenue USD Bn)
15.1.3. MEA Small Molecule API Market Size and Forecast, By Type, 2023-2034 (Revenue USD Bn)
15.1.4. MEA Small Molecule API Market Size and Forecast, By Manufacturer, 2023-2034 (Revenue USD Bn)
15.1.5. MEA Small Molecule API Market Size and Forecast, By Application, 2023-2034 (Revenue USD Bn)
15.2. GCC Global Small Molecule API Market
15.2.1. GCC Small Molecule API Market Size and Forecast, 2023-2034 (Revenue USD Bn)
15.2.2. GCC Small Molecule API Market Size and Forecast, By Type, 2023-2034 (Revenue USD Bn)
15.2.3. GCC Small Molecule API Market Size and Forecast, By Manufacturer, 2023-2034 (Revenue USD Bn)
15.2.4. GCC Small Molecule API Market Size and Forecast, By Application, 2023-2034 (Revenue USD Bn)
15.3. South Africa Global Small Molecule API Market
15.3.1. South Africa Small Molecule API Market Size and Forecast, 2023-2034 (Revenue USD Bn)
15.3.2. South Africa Small Molecule API Market Size and Forecast, By Type, 2023-2034 (Revenue USD Bn)
15.3.3. South Africa Small Molecule API Market Size and Forecast, By Manufacturer, 2023-2034 (Revenue USD Bn)
15.3.4. South Africa Small Molecule API Market Size and Forecast, By Application, 2023-2034 (Revenue USD Bn)
15.4. Rest of MEA Global Small Molecule API Market
15.4.1. Rest of MEA Small Molecule API Market Size and Forecast, 2023-2034 (Revenue USD Bn)
15.4.2. Rest of MEA Small Molecule API Market Size and Forecast, By Type, 2023-2034 (Revenue USD Bn)
15.4.3. Rest of MEA Small Molecule API Market Size and Forecast, By Manufacturer, 2023-2034 (Revenue USD Bn)
15.4.4. Rest of MEA Small Molecule API Market Size and Forecast, By Application, 2023-2034 (Revenue USD Bn)
16. Competitor Analysis
16.1. Company Market Share Analysis, 2023
16.2. Major Recent Developments
17. Company Profiles
17.1. Sun Pharmaceutical Industries Ltd.
17.2. Boehringer Ingelheim International GmbH
17.3. Celgene Corporation
17.4. BASF SE
17.5. Teva Pharmaceutical Industries Ltd.
17.6. Baxter International Inc.
17.7. Pfizer, Inc.
17.8. Cambrex Corporation
17.9. Sanofi S.A.
17.10. AstraZeneca Plc.
17.11. Other Prominent Players
18. Conclusion19. Recommendations

Companies Mentioned

  • Sun Pharmaceutical Industries Ltd.
  • Boehringer Ingelheim International GmbH
  • Celgene Corporation
  • BASF SE
  • Teva Pharmaceutical Industries Ltd.
  • Baxter International Inc.
  • Pfizer Inc.
  • Cambrex Corporation
  • Sanofi S.A.
  • AstraZeneca Plc.

Table Information