Recent advances in pharmacology and brain stimulation have led to the development of novel treatments for psychiatric disorders. These new advances have led to the development of a new subspecialty, Interventional Psychiatry.
Interventional Psychiatry: Road to Novel Therapeutics reviews all specialized treatments including device-based interventions such as electroconvulsive therapy (ECT), repetitive transcranial magnetic stimulation (rTMS), and deep brain stimulation (DBS). This book discusses the procedure-based pharmacologic interventions including ketamine infusion therapy and psychedelic therapies. Internationally contributed, this book outlines the state of the field, as well as implications for training and the role of the interventional psychiatrist in treatment teams.
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Table of Contents
1. Interventional Therapeutics in Psychiatry: beyond pharmaco and psychotherapies? 2. Proposed Curriculum for an Interventional Psychiatry Fellowship Program Part I Transcranial Magnetic Stimulation 3. Mechanisms of action of Transcranial Magnetic Stimulation 4. Transcranial Magnetic Stimulation in Psychiatric Disorders 5. Transcranial Magnetic Stimulation in Neurological Disorders Part II Transcranial Direct Current Stimulation 6. Mechanisms of action of Transcranial Direct Current Stimulation 7. Transcranial Direct Current Stimulation in Psychiatric Disorders 8. Transcranial Magnetic Stimulation in Neurological Disorders Part III. Convulsive Therapies 9. Mechanisms of action of Convulsive Therapies 10. Convulsive therapies in mood disorders 11. Adverse effects and safety of convulsive therapies Part IV. Vagus Nerve Stimulation 12. Mechanisms of action of Vagus Nerve Stimulation 13. VNS for mood disorders Part IV. Interventional pharmacology 14. Ketamine in Psychiatry 15. Psychedelics in Psychiatry 16. Anesthetics in Psychiatry Part V. Deep Brain Stimulation 17. Mechanisms of deep brain stimulation in psychiatry 18. Deep Brain Stimulation for obsessive compulsive disorder 19. Deep Brain Stimulation for depression Part VI. Gamma Knife, Focused Ultrasound and Other Procedures 20. Radiofrequency Lesions for Psychiatric Disorders 21. Gamma knife for Psychiatric indications 22. Focused Ultrasound and other lesioning modalities for Psychiatric Disorders 23. optogenetics and chemogenetics
Authors
Joao L. de Quevedo Professor of Psychiatry at the McGovern Medical School, The University of Texas Health Science Center at Houston, TX, USA.Dr. Jo�o Luciano de Quevedo, MD, PhD, is a Professor of Psychiatry at the McGovern Medical School, the University of Texas Health Science Center at Houston, where he is the Vice-Chair for Faculty Development and Outreach, Director of the Translational Psychiatry Program, and Director of the Treatment-Resistant Depression Clinic. Before moving to Houston, he was a Dean at the University of Southern Santa Catarina Medical School, Crici�ma, SC, Brazil, where he is still an Adjunct Professor of Psychiatry. He is also Editor-in-Chief of the Brazilian Journal of Psychiatry and Director of the Continuous Medical Education Program in Psychiatry (PROPSIQ) of the Brazilian Psychiatric Association. Dr. Quevedo's research interest is neurobiology of psychiatric disorders, particularly mood disorders, and he is a specialist in both unipolar and bipolar treatment-resistant depression. He is author of nearly 600 publications and 10 scientific books.
Andr� R. Brunoni University of S�o Paulo Brazil.Dr. Andr� Brunoni graduated in Medicine in 2004 and specialized in Internal Medicine and Psychiatry in 2007 and 2010. Dr. Brunoni did his PhD from 2010 to 2012 in the University of S�o Paulo, Brazil, with a 4-month fellowship at Spaulding Rehabilitation Hospital, Harvard Medical School. Currently, Dr. Brunoni is the Director of two clinical and research centers in leading university hospitals of the University of S�o Paulo-the Institute of Psychiatry in the Clinics Hospital and the University Hospital. He supervises postgraduate and graduate students as well as medical residents and students. His research involves the use of noninvasive brain stimulation techniques, such as transcranial direct current stimulation, transcranial magnetic stimulation, and "deep� transcranial magnetic stimulation in the treatment of mental disorders, such as mood disorders, obsessive-compulsive disorder, and schizophrenia. He is a very productive and active researcher, with more than 100 published articles in PubMed peer-reviewed journals.
Clement Hamani Sunnybrook Research Institute, Toronto, Canada.Dr. Clement Hamani is the Research Director of the Hurvitz Brain Sciences Program, Senior Scientist at the Sunnybrook Research Institute, Full Professor in Surgery/Neurosurgery at the University of Toronto, preclinical lead of the Harquail Centre for Neuromodulation, and neurosurgeon at the Sunnybrook Health Sciences Centre in Toronto, Canada. Dr. Hamani's research focus is the development of new ways of modulating the function of the nervous tissue, and discovering new applications for techniques that stimulate the brain and spinal cord to treat neurological and psychiatric disorders. His work ranges from basic research in preclinical models to clinical trials.
