34th European Symposium on Computer Aided Process Engineering /15th International Symposium on Process Systems Engineering. ESCAPE-34/PSE2024. Computer Aided Chemical Engineering Volume 53

Table of Contents

Towards an Integrated Wide Approach for Sustainable Upstream Field Recovery

Shakeel Ramjanee, Nilay Shah1



Surrogate Modeling Application for Process System Emissions Assessment: Improving Computational Performances for Plantwide Estimations

Giulio Carnio, Alessandro Di Pretoro, Fabrizio Bezzo, Ludovic Montastruc7



Enhancing Solar Photovoltaic Panel Production: a Novel Machine Learning Approach for Optimizing Mexico's Potential

Francisco Javier Lopez-Flores, Cesar Ramirez-Marquez, Jos� Maria Ponce-Ortega13



Improving Styrene Polymerization Through a Commercial Simulation Software

Jeorge L. S. Amaral, Rodrigo Battisti, Ricardo A. F. Machado, Cintia Marangoni19



Cfd-based Investigation of the Efficiency Enhancement Due to Microstructure Reorientation in Structured Packing

Christopher Dechert, Iris M. Baumh�gger, Eugeny Y. Kenig25



A Lumped Parameter Approach for Determining the Pressure Gradient in Gas-liquid Annular Flows

Nicol� Varallo, Giorgio Besagni, Riccardo Mereu31



Foliar Uptake Models for Biocides: Testing Structural and Practical Identifiability

Enrico Sangoi, Federica Cattani, Faheem Padia, Federico Galvanin37



Dynamic Multiscale Hybrid Modelling of a CHO Cell System for Recombinant Protein Production

Oliver Pennington, Sebasti�n Espinel R�os, Mauro Torres Sebastian, Alan Dickson, Dongda Zhang43



Dynamic Modelling Approaches in Life Cycle Assessment: a Case Study for the Evaluation of Power-to-hydrogen

Laura R. Pi�eiro, Silvia Moreno, �ngel Luis V. Perales, Bernab� A. Fari�as, Pedro Haro49



Transient Flow-assisted Kinetic Modelling and Reaction Network Identification for Pyrazole Synthesis

Fernando Vega-Ramon, Linden Schrecker, Miguel Angel De Carvalho Servia, King Kuok (Mimi) Hii, Dongda Zhang55



Application of Appropriate Kinetic Models in Developing Pharmaceutical Drug Substance Manufacturing Processes

Maitraye Sen, Alonso J. Arguelles61



Daf Turbidity Removal Dynamics Model Employing Lstm Networks with Monte Carlo Dropout

Felipe Matheus Mota Sousa, Ivo Jesus Cunha, Vinicius Mello E Muller, Flavio Vasconcelos da Silva67



Design and Optimization of a Sustainable Process for the Transformation of Glucose into High Added Value Products

Carlos Rodrigo Caceres, Eduardo S�nchez-Ram�rez, Juan Gabriel Segovia-Hern�ndez73



Formulation-independent Pharmaceutical Dry Granulation Model via Gray Box Approach

Kanta Sato, Shuichi Tanabe, Susumu Hasegawa, Manabu Kano79



Bayesian Hybrid Models for Simulation of Microbial Biohydrogen Photo-production Processes

Shraman Pal, Bovinille Anye Cho, Antonio Del Rio Chanona, Dongda Zhang, Max Mowbray85



Loss-in-weight Feeder Performance Prediction Using Machine Learning

Hikaru G. Jolliffe, Carlota Mendez Torrecillas, Gavin Reynolds, Richard Elkes, Hugh Verrier, Michael Devlin, Bastiaan Dickhoff, John Robertson91



Process Design of Carbon-neutral Routes for Methanol Synthesis

Omar Almaraz, Srinivas Palanki, Jianli Hu97



Efficient Use of Energy in Distillation: Advancing Towards the Electrification of the Chemical Industry

Zinet Mekidiche-Martinez, Jos� A. Caballero, Juan A. Labarta103



Modeling Fed-batch Cultures of Yeast for the Production of Heterologous Proteins an Industrial Experimental Study

Micaela Benavides, Pascal Gerkens, Ga�l De Lannoy, Laurent Dewasme, Alain Vande Wouwer109



Performance of Piecewise Linear Models in Milp Unit Commitment: Difference of Convex Vs. J1 Approximation

Felix Birkelbach, Victor S�o Paulo Ruela, Rene Hofmann115



Performance Evaluation of Several Reverse Osmosis Process Configurations for the Removal of N-nitrosomethylethylamine (nmea) from Wastewater

Mudhar Al-Obaidi, Alanood Alsarayreh, Iqbal M. Mujtaba121



Optimizing Lactic Acid Recovery from Vinasse: Comparing Traditional and Intensified Process Configurations

Lucas De Oliveira Carneiro, Romildo Pereira Brito, Karoline Dantas Brito127



Comparison of Machine Learning Based Hybrid Modelling Methodologies for Dynamic Simulation of Chemical Reaction Networks

Harry Kay, Fernando Vega-Ramon, Dongda Zhang133



A Mathematical Framework to Study the Impact of Technological Learning on Portfolio Planning

Pooja Zen Santhamoorthy, Selen Cremaschi139



Dynamic Hybrid Model for Nanobody-based Antivenom Production (scorpion Antivenon) with E. Coli Ch10-12 and E. Coli Nbf12-10.

David Camilo Corrales, Susana Maria Alonso Villela, Balkiss Bouhaouala-Zahar, Julien Cescut, Fayza Daboussi, Michael O'Donohue, Luc Fillaudeau, C�sar Arturo Aceves-Lara145



Hybrid Modeling of Pem Fuel Cell: Machine Learning of Equilibrium Water Content within a 1D Cell Model

Ievgen Golovin, Kilian Knoppe, Christian Kunde, Achim Kienle151



On the Development of Hybrid Models to Describe Delivery Time in Autoinjectors

Andrea Friso, Mark Palmer, Gabriele Bano, Federico Galvanin157



Dynamic Modeling of Particle Size and Porosity Distribution in Fluidized Bed Spray Agglomeration

Eric Otto, Robert D�rr, Achim Kienle, Andreas B�ck, Evangelos Tsotsas163



Doe-integrated Sparse Identification of Nonlinear Dynamics for Automated Model Generation and Parameter Estimation in Kinetic Studies

Wenyao Lyu, Federico Galvanin169



Computational Fluid Dynamics and Trust-region Methods to Optimize Carbon Capture Plants with Membrane Contactors

Hector A. Pedrozo, Grigorios Panagakos, Lorenz T. Biegler175



Dynamic Modelling of Electrodialysis with Bipolar Membranes Using Narx Recurrent Neural Networks

Giovanni Virruso, Calogero Cassaro, Waqar Muhammad Ashraf, Alessandro Tamburini, Vivek Dua, I. David L. Bogle, Andrea Cipollina, Giorgio Micale181



Modelling a Geothermal Vaporiser: a first Step Towards a Digital Twin

Theo Brehmer-Hine, Wei Yu, Brent Young187



Development and Application of a Simplified Non-ideal Mixing Model for Semi-batch Crystallization

Jan Trnka, Giovanni Maria Maggioni, Frantisek Step�nek193



Analysis of the Preferred Ethylene Production Route from Carbon Dioxide at a Supply Chain Level: Results of Mathematical Modelling for a Teesside Case Study

Grazia Leonzio, Nilay Shah199



Comparative Assessment of Flexible Natural Gas Monetisation Processes to Products Under Uncertainties: Agent-based Modelling Approach

Noor Yusuf, Ahmed Al-Nouss, Tareq Al-Ansari205



Production of High-purity Methane via Sorption-enhanced CO2 Methanation in an Adiabatic Packed Bed Reactor

Giuseppe Piso, Piero Bareschino, Claudio Tregambi, Francesco Pepe, Erasmo Mancusi211



Phase-field Modeling for Freeze Crystallization in a Binary System

Xiaoqian Huang, Aurelie Galfr�, Fran�oise Couenne, Claudia Cogn�217



Design and Optimization of a Steam-assisted Adsorption Process for Direct Air Capture

Adam Ward, Maria M. Papathanasiou, Ronny Pini223



Process Robustness Evaluation for Various Operating Configurations of Simulated Moving Bed Chromatography

Kensuke Suzuki, Tomoyuki Yajima, Yoshiaki Kawajiri229



State-based Shrinkage Behavior for Waste Incineration Modeling

Lionel Sergent, Abderrazak M. Latifi, Fran�ois Lesage, Jean-Pierre Corriou, Alexandre Grizeau235



Process Simulation of Biofuel Production from Waste Cooking Oil

Suresh Kumar Jayaraman241



A Virtual Entity of the Digital Twin Based on Deep Reinforcement Learning Model for Dynamic Scheduling Process

Jinglin Wang, Jinsong Zhao247



The Assessment of Lng Export Scenarios for Qatar in the European Gas Market

Majed M.A. Munasser, Sabla Y. Alnouri, Abdelbaki Benamor253



Hybrid Deep Learning Model for Evaluations of Protein-ligand Binding Kinetic Property

Yujing Zhao, Qilei Liu, Yu Zhuang, Yachao Dong, Linlin Liu, Jian Du, Qingwei Meng, Lei Zhang259



Information Sharing for Cost-effective Risk Mitigation in Supply Chains: a Methodological Framework

Shivam Vedant, Rahul Kakodkar, Natasha J. Chrisandina, Catherine Nkoutche, Eleftherios Iakovou, Mahmoud M. El-Halwagi, Efstratios N. Pistikopoulos265



Optimization of Operating Conditions Using a Crystallizer Model with Local Temperature Control

Saki Iizuka, Kano Ishikawa, Sanghong Kim271



System Identification of an Industrial Cascade Refrigeration System

Jun Chang, Wei Yu, James Carson, Brent Young277



Molecular Reconstruction Method of Petroleum Based on Dual Two-dimensional Homologous Series Distributions

Chen Zhang, Yijiong Hu, Tong Qiu283



Process Modelling for Photo-iniferter Raft with Multiple Chain Transfer Agents

Rui Liu, Xiaowen Lin, Xi Chen, Antonios Armaou289



A Study on Thermodynamic Efficiency and Economic Viability of Orc-based Geothermal Hydrogen Production Systems

Jinyue Cui, Muhammad Aziz295



Regional Capacity Expansion Planning of Electricity and Hydrogen Infrastructure: a Norwegian Case Study

Kang Qiu, Espen Flo B�dal, Brage Rugstad Knudsen301



Framework Based on a Coupled Input-yield Model for Infrastructure-driven Agriculture

Farhat Mahmood, Tareq Al-Ansari307



Integrating Effort- and Gradient-based Approaches in Optimal Design of Experimental Campaigns

Marco Sandrin, Beno�t Chachuat, Constantinos C. Pantelides313



Modelling and Simulation of a Forward Osmosis Process

Matej Ruzicka, Ingrid Helgeland, Radoslav Paulen319



Adoption Dynamics of District Heat Networks: an Agent-based Commercial Model

Thomas Cowley, Emma Morris, Timothy Hutty, Solomon Brown325



Assessment of Technical and Economic Viability in the Transformation of Refinery Vacuum Residue Waste Into Cleaner Fuels

Ammr M. Khurmy, Usama Ahmed, Ahmad Al Harbi, Taha Aziz331



Modelling of a Cartridge-based Fixed Bed Radial Flow Reactor for Methanol Synthesis

Frank Sauerh�fer-Rodrigo, Manuel Rodriguez, Ismael Diaz337



Sustainability and Quality-by-digital Design of an Integrated End-to-end Continuous Pharmaceutical Process

Timothy J. S. Campbell, Chris D. Rielly, Brahim Benyahia343



Development of a Fast-charging Protocol Considering Degradation Using High-fidelity Lithium-ion Batteries

Chanho Kim, Minsu Kim, Junghwan Kim349



Applying an Efficient Approach for Modeling and Optimization of Membrane Gas Separation Processes Using Maxwell-stefan Theory

Hector Octavio Rubiera Landa, Joeri F. M. Denayer355



Modelling of the Co-gasification of Waste Plastic and Biomass Using Oxygen-CO2 Mixtures

Nomadlozi L. Khumalo, Bilal Patel361



Impact Assessment of CO2 Capture and Low-carbon Hydrogen Technologies in Colombian Oil Refineries

Erik Lopez Basto, Gijsbert Korevaar, Andrea Ram�rez Ram�rez367



A Task Graph Parallel Computing Architecture for Distillation Column Simulation on Flash Granularity

Shifeng Qu, Shaoyi Yang, Wenli Du, Feng Qian373



Digital Twin Technology in the Thermal Processing Industry of Granular Material Based on the Extended Discrete Element Method (xdem)

Bernhard Peters379



Model-based Design of Experiments for the Identification of Kinetic Models of Amide Formation

Emmanuel Agunloye, Muhammad Yusuf, Thomas W. Chamberlain, Frans L. Muller, Richard A. Bourne, Federico Galvanin385



A Holistic Approach for Model Discrimination, Multi-objective Design of Experiment and Self-optimization of Batch and Continuous Crystallization Processes

Xuming Yuan, Brahim Benyahia391



Computer-aided Assessment of a Droplet Absorber for CO2 Direct Air Capture

Maria F. Gutierrez, Kasimhussen Vhora, Andreas Seidel-Morgenstern, Gabor Janiga, Peter Schulze397



Modelling and Parametric Analysis for Improving Technical Performance of Industrial-scale Basic Oxygen Furnace Gas Fermentation to Isopropyl Alcohol

Gijs J.A. Brouwer, Haneef Shijaz, John A. Posada403



Model-based Determination of a Stationary Phase Gradient in Liquid Chromatography Using Optimal Control Theory

Alexander Eppink, Heiko Briesen409



Design and Simulation of Hydrate-based Desalination Using R-152a Refrigerant

Sief Addeen Aldroubi, Umer Zahid, Hassan Baaqeel415



Microfluidic Dynamics Coupled with Populational Balance Equations to Further Describe Water/diesel Microemulsions

Nadia Gagliardi Khouri, Rubens Maciel Filho421



Cleaning Kinetic Model for Carbohydrates- and Protein-based Stains in Automatic Dishwasher

Jos� E Rold�n-San Antonio, Carlos Amador, Mariano Martin, Kevin Blyth, Vania C. Croce Mago427



From Municipal Solid Waste to Sustainable Aviation Fuel: Process Design

Mohammad Alherbawi, Ridab Khalifa, Yusuf Bicer, Tareq Al-Ansari433



Economic Resilience Evaluation of Wastewater Resource Recovery in Qatar’s Fertilizer Market

Fatima-Zahra Lahlou, Ahmed Al-Nouss, Rajesh Govindan, Tareq Al-Ansari439



Computational Molecular Dynamics in Emerging Biological Fields

Joseph Middleton, Joan Cordiner445



Scoping and Identifying Data-driven Optimization Prospects in the Danish Processing Industry

Adem R.N. Aouichaoui, Brynjolf B. Ernstsson, Peter Jul-Rasmussen, Nicklas H. Iversen, Laurent Vermue, Jakob K. Huusom451



Gcn-based Soft Sensor Utilizing Process Flow Diagram

Hiroki Horiuchi, Yoshiyuki Yamashita457



Hybrid Model-based Design Space Determination for an Active Pharmaceutical Ingredient Flow Synthesis Using Grignard Reaction

Junu Kim, Yusuke Hayashi, Sara Badr, Kazuya Okamoto, Toshikazu Hakogi, Satoshi Yoshikawa, Hayao Nakanishi, Hirokazu Sugiyama463



Development of a Strategy for the Analysis of the Fluid Dynamic Behavior of Sieve Trays for Distillation

Jose Alfredo Paredes-Ortiz, Mario Alberto Rodriguez-Angeles, Vineet Vishwakarma, Markus Schubert, Uwe Hampel, Fernando Israel G�mez-Castro, Mayra Margarita May-Vazquez469



Dynamic Modelling of a Milk Triple Effect Falling Film Evaporator with Mechanical Vapor Recompression

Hattachai Aeowjaroenlap, Jakob Strohm, Isuru Udugama, Wei Yu, Brent Young475



A Pre-train and Fine-tune Paradigm of Fault Detection and Fault Prognosis for Chemical Process

Yiming Bai, Jinsong Zhao481



A Multi-criteria Based Approach for Large-scale Deployment of CO2 Capture, Utilization and Storage

Thuy Thi Hong Nguyen, Satoshi Taniguchi, Takehiro Yamaki, Nobuo Hara, Sho Kataoka487



Accelerating Unsteady Fluid Dynamic Simulations for Taylor-couette Crystallizer Using Snapshot Pod and Recurrent Neural Networks

Osamu Tonomura, Tsuyoshi Maruyama, Atsuto Nishihata, Ken-Ichiro Sotowa493



Process Simulation of Effects of Ammonia Co-firing on the Thermal Performances of the Supercritical Circulating Fluidized Bed Boiler

Seong-il Kim, Won Yang499



Modelling of Pem Electrolyzer Dynamics for Green Hydrogen Production

Dhana Lakshmi Gosu, Anuradha Durvasula, Jagan Annamalai, Abhisek Roy Chowdhary, Guillermo Sanchez Freire505



Discovering Zeolite Adsorption Isotherms: a Hybrid Ai Modeling Approach

Arijit Chakraborty, Akhilesh Gandhi, M. M. Faruque Hasan, Venkat Venkatasubramanian511



Simulation and 3e Assessment of Pre-combustion CO2 Capture Process Using Novel Ionic Liquids for Blue H2 Production

Sadah Mohammed, Fadwa Eljack, Saad Al-Sobhi, Monzure-Khoda Kazi517



Novel Closed-loop Precursor Re-synthesis Assisted by Roasting and Wastewater Electrolysis: Industrial Scaled Design and Simulation

Sunwoo Kim, Jeongdong Kim, Junghwan Kim523



Use of Image Data in Kinetic Model Development for the Design of Mesenchymal Stem Cell Cultivation Processes

Keita Hirono, Yusuke Hayashi, Isuru Udugama, Yuto Takemoto, Ryuji Kato, Masahiro Kino-Oka, Hirokazu Sugiyama529



Ab Initio Prediction of Surface Tension from Fundamental Equations of State Using Density Gradient Theory (dgt)

Anna Sm�dov�, Luk�s Satura, Alexandr Zubov535



Model-based Assessment of Electrochemical Cells and Systems for Atmospheric CO2 Removal

Guokun Liu, Aidong Yang541



Enhancing Unit Operation Design: Leveraging Neural Networks to Enforce Physical Hard Constraints

Jana Mousa, St�phane N�gny, Rachid Ouaret, Alessandro Di Pretoro, Ludovic Montastruc547



Design and Energy Evaluation of a Multi-stage CO2 Separation Process Using Surrogate Model

Yota Fujii, Keigo Matsuda553



Advancing Low-carbon Lng within Qatar: Integrating Ccus and Carbon Tax Strategies

Razan Sawaly, Mohammad Alherbawi, Ahmad Abushaikha, Tareq Al-Ansari559



Process Efficiency Enhancement of Integrated Hydrogen Enrichment and Liquefaction

Muhammad Islam, Ahmad Naquash, Ali Rehman, Moonyong Lee565



Physics-informed Neural Networks and Time-series Transformer for Modeling of Chemical Reactors

Giacomo Lastrucci, Maximilian F. Theisen, Artur M. Schweidtmann571



Techno-economic Analysis of H2 Extraction from Natural Gas Transmission Grids

Homa Hamedi, Torsten Brinkmann, Jonathan M�dler, Leon Urbas577



Aiding Modular Plant Design by Linking Capability and Transformation Models

Amy Koch, Florian Kunkel, Louise Theophile, Veronica De La Vega Hernandez, Jonathan M�dler, Leon Urbas583



Optimization-based Design of Distillation Columns Using Surrogate Models

Marc Caballero, Anton A. Kiss, Ana Somoza-Tornos589



Towards Pea Matching from Simulation as Part of a Digital Twin Concept for Scale-up in Modular Plants

Amy Koch, Jonathan M�dler, Andreas Bamberg, Leon Urbas595
Comparative Study on Hydrothermal Gasification and Thermal Gasification via Hydrothermal Carbonization of Digestate Residues from Anaerobic Digestion

Fadilla Noor Rahma, Khanh-Quang Tran, Roger Khalil601



Strategic Decision-making in Duopolistic Energy and Water Markets: Examining Competition Versus Cooperation for Farm Siting Optimization

Sarah Namany, Maryam Haji, Mohammad Alherbawi, Tareq Al-Ansari607



Dynamic Modeling of Precipitation in Electrolyte Systems

Niklas Kemmerling, Sergio Lucia613



Assessing Climate Variability in Tomato Supply Chain Optimization: a Multi-objective Approach for Qatar's Tomato Imports

Bashar Hassna, Sarah Namany, Mohammad Alherbawi, Adel Elomri, Tareq Al-Ansari619



Developing the Final Product Attribute Prediction Model in a Continuous Direct Compression Process

Yuki Kobayashi, Sanghong Kim, Takuya Nagato, Takuya Oishi, Manabu Kano625



A Genetic Algorithm-based Design for Hydrogen Pipeline Infrastructure with Real Geographical Constraints

Joseph Hammond, Manou Rosenberg, Solomon Brown631



An Attainable Region Approach to Chemical Reaction Equilibrium

Diane Hildebrandt, James Fox, Neil Stacey, Celestin Sempuga637



A Nash Equilibrium Approach to Supply Chain Design of Oligopoly Markets Under Uncertainty

Asimina Marousi, Karthik Thyagarajan, Jose M. Pinto, Lazaros G. Papageorgiou, Vassilis M. Charitopoulos643



Modelling of Pcl Production: Multi-scale Approach and Parameter Estimation

Jakub Stas, Alexandr Zubov649



Improving Food Security Through Water Management and Allocation: a Geospatial Optimization Approach

Maryam Haji, Mohammad Alherbawi, Sarah Namany, Tareq Al-Ansari655



Technical Analysis of Ammonia Converter Catalyst Installation in Ammonia 1b Pt Pupuk Kujang Plant

Zulkarnaen Arsadduddin661



Model-based Design of Experiments for Isotherm Model Identification in Preparative Hplc

Konstantinos Katsoulas, Maximillian Besenhard, Federico Galvanin, Luca Mazzei, Eva Sorensen667



Modeling of Carbon Offsetting Industries for Performance Prediction of Emissions Trading Systems

Soo Hyoung Choi673



Multi-objective Optimization for Pharmaceutical Supply Chain Design: Application to Covid-19 Vaccine Distribution Network

Jonathan J. Cuevas-Lopez, Catherine Azzaro-Pantel, Sofia De-Leon Almaraz679



The Reverse Water-gas Shift Reaction as an Intermediate Step for Synthetic Jet Fuel Production: a Reactor Sizing Study at Two Different Scales

Antoine Rouxhet, Gr�goire L�onard685



Modelling, Simulation, Exergy and Economic Analyses of Thermal Cracking of Propane Using CO2 and Steam as Diluents

Yao Zhang, Hui Yan, Daotong Chong, Joan Cordiner, Meihong Wang691



Moisture Content Prediction Model of a Wet Granulator Fluid Bed Drier System Based on Lstm Networks

Kai Liu, Mahdi Mahfouf, James Litster, Daniel Coca697



Simulation Study of a Hybrid Cryogenic and Membrane Separation System for Sf6 Recovery from Aged Gas Mixture in Electrical Power Apparatus

Huong Trang Vo, Lujia Chen, Patricia Gorgojo703



Investigating Fluid Flow Dynamics in Triply Periodic Minimal Surfaces (tpms) Structures Using CFD Simulation

Kasimhussen Vhora, Tanya Neeraj, Dominique Thevenin, Gabor Janiga, Kai Sundmacher709



A Deep Learning-based Energy and Force Prediction Framework for High-throughput Quantum Chemistry Calculations

Guoxin Wu, Qilei Liu, Jian Du, Qingwei Meng, Lei Zhang715



Mathematical Modeling of an Enzyme Catalyzed Transamination Reaction with Integrated Product Removal

Jessica Behrens, Sven Tiedemann, Jan Von Langermann, Achim Kienle721



Process Integration of Urea Production with Methane Pyrolysis for Reduced Carbon Emissions

Muhamad Reda Galih Pangestu, Umer Zahid727



Modelling Study of CO2 Sequestration by Mineral Waste Carbonation Process

Natalia Vidal De La Pena, Dominique Toye, Gr�goire L�onard733



Evaluation of Two-dimensional Pseudo-homogeneous and Heterogeneous Modeling Approaches in Steam-methane Reforming Reactors

Chengtian Cui, Yufei Zhao, Cornelius Masuku739



Implementing a Model Library for Wastewater Treatment Plants in an Equation-oriented Simulator: Numerics and Architecture

Jochen Steimel, Sahand Iman Shayan745



Waste Heat Recovery from Pem Electrolyzer for Desalinated Water Production in Polygeneration Systems

Artur S. Bispo, Leonardo O.S. Santana, Gustavo S. dos Santos, Chrislaine B. Marinho, Daniela Hartmann, Fernando L.P. Pessoa751



Modeling and Optimizing Sugarcane-livestock Integration Systems in Brazil

Igor L.R. Dias, Terezinha F. Cardoso, Ana C.M. Jimenez, Jo�o G.O. Marques, Luis G. Barioni, Fl�via Barbosa, Adriano P. Mariano, Marcelo P. Cunha, Antonio Bonomi757



Waste-to-x: an Enviro-economic Assessment of Circular Chemical Production via Municipal Solid Waste Gasification

Ben Lyons, Saxon Stanley, Andrea Bernardi, Beno�t Chachuat763



Vulnerability of Microbial Communities to Dishonest Signals: a Biology Driven Complexity Reduced Model

Jian Wang, Ihab Hashem, Satyajeet S. Bhonsale, Jan F.M. Van Impe769



Accelerating Steam Cracking Simulations with Surrogate-assisted Parameter Estimation

Qiming Zhao, Dong Qiu, Kexin Bi, Tong Qiu775



The Effect of Location and Inter-cluster Networks on the Optimal Decarbonization of Ammonia Production

Julia L. Tiggeloven, Charidimos Makrakis, Andr� P.C. Faaij, Gert Jan Kramer, Matteo Gazzani781



Applicability of Energy Storage for Mitigating Variability of Renewable Electricity Considering Life Cycle Impacts

Ayumi Yamaki, Shoma Fujii, Yuichiro Kanematsu, Yasunori Kikuchi787



Pinch Curves Computation Using Differential Continuation Algorithm

Nataliya Shcherbakova, Ivonne Rodriguez-Donis, Vincent Gerbaud793



Assessment of Plastic Recycling Technologies Based on Carbon Resource Circularity Considering Feedstock and Energy Use

Takuma Nakamura, Shoma Fujii, Aya Heiho, Heng Yi Teah, Yuichiro Kanematsu, Yasunori Kikuchi799



Optimal Experimental Design for (semi-)batch Crystallization Processes

Gustavo L. Quill�, Wannes Mores, Satyajeet S. Bhonsale, Alain Collas, Christos Xiouras, Jan F.M. Van Impe805



Novel Process for Bio-jetfuel Production Through the Furan Pathway. Techno-economic, Environmental and Safety Assessment

Melissa Pamela Hinojosa-Esquivel, Cesar Ramirez-Marquez, Julio Cesar Velazquez-Altamirano, Jos� Quiroz-Ramirez, Juan Gabriel Segovia-Hern�ndez, Gabriel Contreras-Zarazua811



Embedding Physics into Neural Odes to Learn Kinetics from Integral Reactors

Tim Kircher, Felix A. D�ppel, Martin Votsmeier817



Sustainable Acetaldehyde Synthesis from Renewable Ethanol: Analysis of Reaction and Separation Processes

Jean Felipe Leal Silva, Rubens Maciel Filho823



Operational Condition Optimization of Schinus Terebinthifolius Supercritical Extraction Using Machine Learning Models

Ana L.N. Santos, Leonardo O.S. Santana, Victor L.S. Dias, Ana L.B. Souza, Fernando L.P. Pessoa829



Optimizing Circular Economy Levers to Achieve Global Sustainability

Shubham Sonkusare, Yogendra Shastri835



Climate Change Adaptation Measures for Water-stressed Thermal Power Plants in India

Reshma Shinde, Yogendra Shastri, Anand B. Rao841



Techno-economic Impacts of Using Alternative Carbon-based Feedstocks for the Production of Methanol

James Tonny Manalal, Mar P�rez-Fortes, Andrea Ram�rez Ram�rez847



An Application of a New Nonlinearity Measure to a Rotary Dryer Model

Jan M. Scha�berger, Anton Ponomarev, Veit Hagenmeyer, Lutz Gr�ll853



Reduction of an Aerated Fermenter CFD Model Using Proper Orthogonal Decomposition

Pedro M. Pereira, Rui C. Martins, Bruno S. Ferreira, Fernando P. Bernardo859



A Techno- Economic Evaluation of Potential Routes for Industrial Biosolids Conversion

Hesan Elfaki, Dhabia M. Al-Mohannadi865



A Rigorous Integrated Approach to Model Electrochemical Regeneration of Alkaline CO2 Capture Solvents

Fariborz Shaahmadi, Katia Piscina, Qingdian Shu, Sotirios Efstathios Antonoudis, Sara Vallejo Casta�o, Philip Loldrup Fosb�l, Uffe Ditlev Bihlet, Mijndert Van Der Spek871



Global Modelling and Simulation of Essential Oil Extraction Processes

Zouhour Limam, Catherine Azzaro-Pantel, Noureddine Hajjaji, Mehrez Romdhane, Jalloul Bouajila877



Mathematical Issues in Bilevel Mixed-integer Linear Programming Applied to Systems Biology.

Guilherme De Olivera Mendes Ohira, Galo A.C. Le Roux883



Combining Energy System Planning with Carbon Emissions Trading Optimisation for Decarbonisation of Emerging Economies

Gul Hameed, Purusothmn Nair S. Bhasker Nair, Raymond R. Tan, Dominic C. Y. Foo, Michael Short889



Optimization of a Reactive Distillation Process to Produce Propylene Glycol as a High Value-added Glycerol Derivative

Jahaziel Alberto Sanchez-Gomez, Fernando Israel G�mez-Castro, Salvador Hern�ndez895



Stepwise Parameter Fitting to Combine Industrial and Pilot Plant Datasets

Per Julian Becker, Benoit Celse901



A Bilevel Framework for Environmental and Economic Optimisation of Hydrogen Supply Chains

Vincent Jacquot, Catherine Azzaro-Pantel, Sylvain Bourjade, Catherine M�ller907



Economic and Environmental Optimization in Sustainable Jet Fuel Production from Butanol

Angel Eduardo Garcia-Hernandez, Juan Gabriel Segovia-Hern�ndez, Eduardo S�nchez-Ram�rez, Jos� Quiroz-Ramirez913



Latent State Space Extension for Interpretable Hybrid Mechanistic Models

Judit Aizpuru, Maxim Borisyak, Peter Neubauer, Mariano Nicol�s Cruz-Bournazou919



Optimizing Deep Neural Networks Through Hierarchical Multiscale Parameter Tuning

Bogdan Dorneanu, Sushen Zhang, Vassilios S. Vassiliadis, Harvey Arellano-Garcia925



Simulation of Hydrogen-methane Separation with Pressure Swing Adsorption

Viktor Kalman, Aleksander Makaruk, Ezgi Engin, Anton Balla, Michael Harasek931



Reverse Supply Chain Network Design of a Polyurethane Waste Upcycling System

Dalga Merve �zkan, Sergio Lucia, Sebastian Engell937



Design and Optimization of Green Hydrogen Production System with Wind-solar Coupled Natural Gas Power Generation Considering Carbon Emission: the Case of China

Tingting Zhao, Yan Wu, Yufei Wang, Xiao Feng943



A Comprehensive Gray-box Framework for High-fidelity Process Simulation Calibration

Jaime David Ponce-Rocha, David Camilo Corrales949



Analysis of Calcium Citrate Salts as Raw Material for Tributyl Citrate Bio-plasticizer Production: Kinetic Modeling, Process Simulation, and Optimization

Andres F. Cabeza, Alvaro Orjuela, David E. Bernal Neira955



Modeling Hydrothermal Gasification of Digestate Sludge: Reaction Kinetic from Molecular Simulations

Do Tuong Ha, Khanh-Quang Tran, Thuat T. Trinh961



Assessment of the Sustainability of Intensified CO2 Capture Schemes

Melanie Coronel-Munoz, Ana Gabriela Romero-Garcia, Brenda Huerta-Rosas, Eduardo S�nchez-Ram�rez, Juan Gabriel Segovia-Hern�ndez967



Development of Electricity Generation System by Combining Plastic Steam Gasification with Solid Oxide Fuel Cells

Khaled Abouemara, Muhammad Shahbaz, Samir Boulfrad, Gordon Mckay, Tareq Al-Ansari973



Integrated Solid Oxide Systems: Advancing Efficiency in Power Generation Through Fuel Cell-electrolyzer Coupling with Diverse Fuels

Xinyi Wei, Shivom Sharma, Arthur Waeber, Jan Van Herle, Fran�ois Marechal979



Refining Sofc Performance: Parameter Estimation and Model Validation for Dynamic Energy System Optimization

Arthur Waeber, Xinyi Wei, Shivom Sharma, Jan Van Herle, Fran�ois Marechal985



Modeling of the Coupling of Dissolution and Crystallization in the Digestion Tank of a Wet Phosphoric Acid Manufacturing Process

Sanae Elmisaoui, Abderrazak M. Latifi, Fadoua Farghi, Safae Elmisaoui, Lhachmi Khamar991



Optimization of High-performance Membrane Processes for Post-combustion Carbon Capture

Marina Micari, Kumar Varoon Agrawal997



Modeling of the Dynamic Behaviour of Fischer-tropsch Fixed-bed Reactors: a Pseudohomogeneous Approach

Egydio Terziotti Neto, Rita M. B. Alves, Reinaldo Giudici1003



Variable Structure Simulation and Optimization of Start-up of Batch Distillation Columns

Nikhil Sharma, Kannan M. Moudgalya, Sunil Shah1009



Dynamic Modeling and Validation of an Industrial Vacuum Thermodeasphalting Column for the Regeneration of Used Oil

Francesco Negri, Kristiano Prifti, Simone Caspani, Francesco Gallo, Flavio Manenti1015



Integrated Recycling of End-of-life Tires Through Pyrolysis for Fuels Production with Hydrogen Recovery

Simone Caspani, Anna Nova, Francesco Negri, Flavio Manenti1021



Dynamic Modelling and Surrogate-based Optimization of Auto-thermal Reforming for Enhanced Hydrogen Production

Hao Chen, Konstantinos Kyprianidis1027



Using Mathematical Optimization for the Transition to Sustainable and Circular Agriculture

Jan Drofenik, Bojan Pahor, Zdravko Kravanja, Zorka Novak Pintaric1033



An Industrial Case Study of Dynamic Adsorption Simulation for Volatile Organic Compound (voc) Pharmaceutical Emission Abatement

Vasiliki E. Tzanakopoulou, Michael Pollitt, Daniel Castro-Rodriguez, Dimitrios I. Gerogiorgis1039



Techno-economic Analysis for Biogas Reforming Using Pswa: Case Study on Methanol Synthesis

Loretta Salano, Marcello M. Bozzini, Flavio Manenti1045



A Novel Approach to Scheduling Water Injection for Energy Efficiency in Ghawar Oilfield

Abdullah Alghazal1051



Modeling the Market Fluctuations of Ammonia Price

Andrea Isella, Davide Manca1057



Economic Optimization of the Synthesis Section of a Small-scale Biogas-to-methanol Plant

Marcello M. Bozzini, Loretta Salano, Carlo Pirola, Flavio Manenti1063



Present Status of Mixed Plastic Waste Pyrolysis: Plant Simulation Through Aspen Hysys

Stefano Redaelli, Maurizio Masi, Davide Alberti, Edoardo Vitto, Flavio Manenti1069



Evaluation on Various Pathways for Converting CO2 Into Chemicals

Bor-Yih Yu1075



Transferable Mini-blender Performance Impact on Continuous Direct Compaction Tablets Using a Modified Kushner-moore Approach.

Hikaru G. Jolliffe, Colette Tierney, Ecaterina Bordos, Carlota Mendez Torrecillas, Martin Prostredny, Ebenezer Ojo, Richard Elkes, John Robertson1081



Design and Planning of Socially Responsible Pharmaceutical Supply Chains Considering Procurement Strategies

In�s Duarte, Bruna Mota, T�nia Pinto-Varela, Ana Amaro, Ana Paula Barbosa-Povoa1087



Techno-economic and Environmental Assessment of Plastic Waste Pyrolysis: from a Linear to a Circular Economy

Christine El Khoury, Laureano Jimenez, Carlos Pozo1093



Modeling Substrate Degradation in Upflow Anaerobic Sludge Blanket Reactors

Federico Moretta, Luisa Carbone, Giulia Bozzano1099



Modeling Framework for Optimization of the Life Cycle Sustainability of Lithium-ion Batteries by Nickel Manganese Cobalt Recycling Process

Minseong Kim, Jeongdong Kim, Junghwan Kim, Hyungjoon Yoon, Pieter Nachtergaele, Il Moon1105



Efficient Numerical Methods for Dynamic Simulation of Fixed-bed Reactors

Joachim Weel Rosbo, Anker D. Jensen, John Bagterp J�rgensen, Jakob K. Huusom1111



Modelling and Investigation of Continuous Ideal Flow Crystallizer with Multidimensional Population Balance Equations

Laszlo Balogh, Attila Egedy, �gnes B�rk�nyi1117



Hydrogen Production from Biogas with Electrified Steam Methane Reforming: System Optimization with Renewable Generation and Storages

Andrea Nava, Davide Remondini, Matteo Lualdi, Stefano Campanari, Matteo C. Romano1123



Ontology-driven Automation of Process Modelling and Simulation

Alberto Rodriguez-Fernandez, Vinay Kumar Gautam, Heinz A. Preisig1129



Towards a Combined, Integrated, and Adaptable Bioethanol and -ethylene Process Leveraging Flexible Ratios in Hybrid Production

Christoph Huber, Merlin Alvarado-Morales, G�rkan Sin1135



Leveraging Digital Twin Modeling for Anaerobic Digesters Using Anaerobic Digestion Model No. 1 (adm1) and Neural Network within the Pyomo Framework

Mayowa F. Oladele, George M. Bollas1141



Revitalizing Plastic Waste with Pyrolysis: a Unisim Design� Simulation Case Study for Renewable Energy Production from Car Fluff

Mariangela Guastaferro, Letizia Marchetti, Marco Vaccari, Cristiano Nicolella, Leonardo Tognotti1147



Modelling Natural Gas Dehydration by Adsorption under High CO2 Conditions

Yuri Alves, Felipe R. Pinto, Felipe C. Cunha, Argimiro R. Secchi, D�rley Melo, Amaro G. Barreto Jr.1153



Haber-bosch Process Alternatives for the Production of Green Ammonia

Jo�o Leit�o, Catarina G. Braz, Henrique A. Matos1159



Overcoming the Challenges of Dynamic Systems in Steady-state Simulations: the Use of Meta-modeling as a Surrogate for Complex Kinetic Models

Andrew M. Elias, Carina L. Gargalo, Cristiane S. Farinas, Krist V. Gernaey1165



An Ionic Liquid Mixture Design for CO2 Capture Through Bayesian Optimization and Molecular Dynamics Simulation

Dulce Maria De La Torre-Cano, Miguel Angel Gutierrez-Limon, Antonio Flores-Tlacuahuac, Mauricio Sales-Cruz1171



A Systems Approach to Model Nonconventional Streams Applied to Biocrude Production from Hydrothermal Liquefaction

Ioannis Aslanoglou, Konstantinos Anastasakis, C. Michalopoulos, Effie Marcoulaki, Antonis Kokossis1177



Assessment of Low-carbon Alternative Fuels in Maritime Integrated with Ccs on Board

Nefeli Roufogali, Konstantinos A. Pyrgakis, Antonis Kokossis1183



Facilitating the Shift Toward an Environmentally Friendly Plastic Waste Management Economy Through Mathematical Optimization

Oluwadare Badejo, Borja Hernandez, Marianthi G. Ierapetritou1189



Optimal Loading of Porphyrin in Porphyrin@bi12o17cl2 Heterojunction: Application in Photocatalysis

Osemeikhian Ogbeifun, Shepherd M. Tichapondwa, Evans M.N. Chirwa1195



Process Intensification Opportunity for Reactive-extractive Distillation: a New Configuration for Ternary Azeotropic Separation

Zong Yang Kong, Yu-Ying Chen, Juan Gabriel Segovia-Hern�ndez, Hao-Yeh Lee1201



An Intensified-integrated Supercritical Extraction-vacuum Distillation-reactive Distillation Process to Produce Phytosterols, Glycerol and Ultra-clean Biodiesel from Crude Vegetable Oils

Eduardo S. P�rez-Cisneros, Ver�nica Rodr�guez-L�pez, Ricardo Morales-Rodriguez, Edgar I. Murillo-Andrade1207



Techno-economic Evaluation of Novel Dual-function Reactor for Direct Air Capture Applying Superstructure Optimisation

Meshkat Dolat, Melis S. Duyar, Michael Short1213



Synthesis of Heat-integrated Distillation Sequences Considering Vapor Recompression under the Constraint of Fossil Energy Consumption

Fangjun Ye, Yiqing Luo, Shengkun Jia, Xigang Yuan1219



Sustainability Assessments of Styrofoam Waste Recycling for Styrene Monomer Recovery: Economic and Environmental Impact

Eprillia Intan Fitriasari, J. Jay Liu1225



Techno-economic and Life Cycle Assessments of the Utilization of Carbon-free Energy Sources as an Alternate Fuel in Naphtha Cracker

Eprillia Intan Fitriasari, J. Jay Liu1231



Optimization of the Catalytic Cracking Process and Biodiesel Coproduction Supply Chain Considering Seasonal Factors

Wenhui Zhang, Yiqing Luo, Xigang Yuan1237



Analyzing a Database of Digitalized Process Flowsheets to Extract Relevant Initialization Structures for Evolutionary Process Synthesis Methods

Jean-Marc Commenge, Andres Pina-Martinez1243



Robust Scheduling of Energy Systems Under Forecasting Uncertainty a Multi-parametric Optimization Approach

Rahul Kakodkar, Dustin Kenefake, Harsh Shah, Iosif Pappas, C. Doga Demirhan, Mete Mutlu, Xiao Fu, Efstratios N. Pistikopoulos1249



Optimal Design of Heat Pump Assisted Distillation Sequences

Jos� A. Caballero, Juan A. Labarta, Zinet Mekidiche-Martinez1255



Scaling Up and Down Power-to-methane Facilities with CO2 Capture: Towards Modular Design

Diego Santamaria, Antonio Sanchez, Mariano Martin1261



A Hierarchical Selection and Decision Matrix for Energy-efficient Intensified Distillation Technologies

Qing Li, Ana Somoza-Tornos, Anton A. Kiss1267



Multi-objective Optimization Approach for Enhancing Flexibility of a Pharmaceutical Tableting Process

Ilias Bouchkira, Brahim Benyahia1273



Hybrid Artificial Intelligence-based Process Flowsheet Synthesis and Design Using Extended Sfiles Representation

Vipul Mann, Mauricio Sales-Cruz, Rafiqul Gani, Venkat Venkatasubramanian1279



Progressive Hedging Decomposition for Solutions of Large-scale Process Family Design Problems

Georgia Stinchfield, Jean-Paul Watson, Carl D. Laird1285



Constructing a Knowledge Graph for Automated Hazop Analysis

Zhiyuan Li, Jinsong Zhao1291



Distillation Electrification Through Optimal Use of Heat Pumps

Akash Nogaja, Mohit Tawarmalani, Rakesh Agrawal1297



Computer-aided Molecular and Process Design (campd) for Ionic Liquid Assisted Extractive Distillation of Refrigerant Mixtures

Ashfaq Iftakher, Rafiqul Gani, M. M. Faruque Hasan1303



Recycling Rare Earth Elements from End-of-life Electric and Hybrid Electric Vehicle Motors

Christopher Laliwala, Ana Torres1309



Rule-based Decision Framework for the Digital Synthesis of Optimal Pharmaceutical Processes

Yash Barhate, Daniel J. Laky, Daniel Casas-Orozco, Gintaras Reklaitis, Zoltan Nagy1315



Synthesis, Characterization and Simulation of Thin Perovskite Films Based on Calcium Titanate (catio3) with Possible Application in Solar Modules

Gerardo Hern�ndez-Reyes, Guillermo Adolfo Anaya-Ruiz, Pascual Eduardo Murillo-Alvarado, Jose Joel Roman-Godinez, Manuel Salvador Sanchez-Ibarra, Alejandra Guadalupe Andrade-Partida, Gabriela Guadalupe Esquivel-Barajas1321



Cfd-based Design of Laminated Microdevice with 3D Serpentine Channel for Submillisecond Mixing

Kazuki Okamoto, Heejin Kim, Osamu Tonomura1327



Global Sensitivity Analysis on System Design Parameters of Silver Nanoparticles Production

Ziyi Han, Heng Yi Teah, Yasunori Kikuchi1333



Intensified Biodiesel Production from Waste Palm Oil in a Plug Flow Reactor

Andrea F. Barcia-Quimi, Kelly Beltran-Borbor, Angelo Piza-Espinoza, Diana Tinoco-Caicedo1339



Rational Function-based Approach for Integrated Ionic Liquid Solvent Selection and Extractive Distillation Process Design

Sahil Sethi, Xiang Zhang, Kai Sundmacher1345



Exergy-based Optimization for the Synthesis of Heat Pump Assisted Distillation Columns

Mirko Skiborowski, Kai Fabian Kruber1351



Small-scale Ammonia Production: a Superstructure Approach

Alonso Martinez, Thien A. Huynh, Christopher Varela, Jimmy Faria, Edwin Zondervan1357



Detailed Design of Shell and Tube Heat Exchangers with Considering Fouling

Yi Cui, Chenglin Chang, Yufei Wang1363



Glycerol Valorisation to Glycerol Carbonate: Process Synthesis, Design and Control

Prakhar Srivastava, Aayush Gupta, Nitin Kaistha1369



System Optimization of Hybrid Processes for CO2 Capture

Luca Riboldi, Sai Gokul Subraveti, Rub�n Mocholi Monta��s, Donghoi Kim, Simon Roussanaly, Rahul Anantharaman1375



Magnesia-based Binders for Stabilizing and Improving Soft Soils

Mohamed Harun, Abdullahi Abdulrahman Muhudin, Umair Ali, Hammad Raza Khalid, Asad Hanif1381



Effective Selection of Green Organics and Natural Deep Eutectic Solvents as Advanced Entrainers by Cosmo-rs and Group Contributions Methods for Enhanced Design of Extractive Distillation

Dhoni Hartanto, Boelo Schuur, Anton A. Kiss, Andr� B. De Haan1387



Stochastic Technoeconomic Analysis and Optimization of Batch and Continuous Crystallization for Sustainable Pharmaceutical Manufacturing Under Supply Delays

Jungsoo Rhim, Zoltan Nagy1393



Global System Analysis of On-line Comprehensive Two-dimensional Liquid Chromatography in gPROMS

Monica Tirapelle, Dian Ning Chia, Fanyi Duanmu, Maximillian Besenhard, Luca Mazzei, Eva Sorensen1399



Optimal Design and Sizing of Hres-powered Electrochemical Microsynthesis System

Weigu Wen, Zhihong Yuan1405



Optimal Design of an Energy-integrated Biogas-powered Fuel Cell System

Vikram Uday, Sujit Jogwar1411



Superstructure Modeling of Lithium-ion Batteries for an Environmentally Conscious Life-cycle Design

Tomoya Yonetsuka, Ayumi Yamaki, Aya Heiho, Yuichiro Kanematsu, Heng Yi Teah, Yasunori Kikuchi1417



Dynamics of Dibenzyltoluene Hydrogenation and Dehydrogenation Reactors: Design and Simulation

Pietro Delogu, Elena Barbera, Andrea Mio, Alberto Bertucco, Maurizio Fermeglia1423



Flexible Operation Assessment of Adsorption-based Carbon Capture Systems via Design Space Identification

Haditya K. Purwanto, Steven Sachio, Adam Ward, Ronny Pini, Maria M. Papathanasiou1429



Designing Li-ion Battery Recycling Networks

Pablo Bernal, Pablo Miranda, Nathalie Jamett, Francisco Tapia, Sebastian Herrera-Leon1435



Design of Large-scale Industrial Water Networks Based on Multiple Objective Mathematical Programming

Francisco J.G. Patrocinio, Ricardo N. Dias, Hugo M.D. Carabineiro, Henrique A. Matos, Nuno M.C. Oliveira1441



Superstructure-based Optimization for Assessing Defossilization Pathways in Petrochemical Clusters

Michael Tan, Paola Ibarra-Gonzalez, Igor Nikolic, Andrea Ram�rez Ram�rez1447



Optimizing Circular Economy Pathways: Multi-criteria Decision-making Tool for Chemical Recycling of Plastic Wastes

Virgil Cabo, Adrian Pacheco-Lopez, Gr�goire L�onard, Antonio Espu�a1453



Supply Chains Design for Sustainability: Addressing Correlated Uncertainty in Life Cycle Inventory

Raquel Salcedo-Diaz, Florencia L. Garcia-Castro, Ruben Ruiz-Femenia, Jos� A. Caballero1459



Comparative Study of Classifier Models to Assert Phase Stability in Multicomponent Mixtures

Lifeng Zhang, Tanuj Karia, Gustavo Chaparro, Kainath Sahebzada, Beno�t Chachuat, Claire S. Adjiman1465



Design of Chemical Recycling Processes for Pur Foam under Uncertainty

Patrick Lotz, Luca Bosetti, Andr� Bardow, Sergio Lucia, Sebastian Engell1471



Dynamic Analysis of Reductant Feed Method on Nh3 Synthesis from Exhaust NO Gas Using No-co-h2o-h2 Reaction

Huichan Hwang, Hideyuki Matsumoto, Teruoki Tago, Yuichi Manaka, Tetsuya Nanba1477



Computer-aided Design of Intensified Separation Sequences for a Complex Mixture of Renewable Hydrocarbons

Isaac Oliva-Gonz�lez, Araceli Guadalupe Romero Izquierdo, Claudia Guti�rrez-Antonio, Fernando Israel G�mez-Castro, Salvador Hern�ndez1483



Integration of Plant Scheduling Feasibility with Supply Chain Network Under Disruptions Using Machine Learning Surrogates

Daniel Ovalle, Javal Vyas, Carl D. Laird, Ignacio E. Grossmann1489



Sustainability Assessment of Direct Air Capture and Utilization Processes at Early-stage

Wonsuk Chung, Hyunyoung Kim, Ung Lee1495



Optimization with Uncertainty for Pharmaceutical Process Design Ibuprofen Synthesis as Case Study

Tuse Asrav, Merlin Alvarado-Morales, G�rkan Sin1501



Modelling\simulation and Optimization of Large-scale Post-combustion CO2 Capture Using a Rotating Packed Bed Absorber and Packed Bed Stripper

Olajide Otitoju, Meihong Wang1507



Sustainability-driven Conceptual Process Design at the Cooperative Cosun

Sara Concei��o, Farzad Mousazadeh, John A. Posada, Juan Gutierrez, P.L.J. Swinkels, Andr� B. De Haan1513



Towards Ph Swing-based CO2 Mineralization by Calcium Carbonate Precipitation: Modeling and Experimental Analysis

Chinmay Hegde, Andreas Voigt, Kai Sundmacher1519



Analysis of the Catalytic Splitting of H2s for H2 Production

Anna Nova, Simone Caspani, Flavio Manenti1525



Spatially Distributed Power-to-methanol Plants in Dissimilar Locations: Specific or Standardized Designs?

Tibor Svitnic, Kai Sundmacher1531



Flow Regimes and Reactivity Assessment in Arrow- and X-microreactors: a Combined Numerical and Experimental Approach

Sara Tomasi Masoni, Alessandro Mariotti, Maria Vittoria Salvetti, Chiara Galletti, Elisabetta Brunazzi1537



Theoretical Control Properties Assessment for a Carbon-hydrogen-oxygen Symbiosis Network with Intensified Processes

Maricruz Juarez Garcia, Juan Gabriel Segovia-Hern�ndez, Jos� Maria Ponce-Ortega, Gabriel Contreras-Zarazua1543



Nonlinear Model Predictive Control for Modified Claus Process

Jialin Liu, Hao-Che Chien, David Shan-Hill Wong, Chun-Cheng Chang1549



Model-based Process Development and Operation of a Fluid Bed Granulation Unit to Manufacture Pharmaceutical Tablets

Salvador Garcia Mu�oz, Maitraye Sen, Shashwat Gupta, Ronald K. Ruff, Pedro De Azevedo Delou1555



Evaluating Performance of Hierarchical Scheduling Frameworks for Varying Matte Grades in Copper Smelting Process

Hussain Ahmed, Matti Vilkko1561



Emission Oriented Scheduling Optimization for Sustainable Processes

Alessandro Di Pretoro, Ingy Tageldin, Ludovic Montastruc1567



Analyzing the Effects of Control Strategies for Determining Process Feasible Space

Margherita Geremia, Fabrizio Bezzo, Marianthi G. Ierapetritou1573



Data-driven Chance-constrained Optimization for Minimizing the Influence of Material Uncertainty on Product Quality

Qingbo Meng, I. David L. Bogle, Vassilis M. Charitopoulos1579



Model Predictive Control of Bioreactors Based on a Reformulation of Dynamic Metabolic Network Models

Marius Fredriksen, Rafael David De Oliveira, Caroline Satye Nakama, Johannes J�schke1585



Characterization and Analysis of Multistage Stochastic Programming Problems with Type Ii Endogenous Uncertainty to Develop Universally Applicable Bounding Approaches

Yasuhiro Shoji, Selen Cremaschi1591



Fault Detection and Diagnosis on a Gas-lifted Oil Well Network Control System

Rafael David De Oliveira, Edmary Altamiranda, Johannes J�schke1597



Multi-objective Optimization of Forced Periodic Operation of Methanol Synthesis in a Fixed-bed Reactor

Johannes Leipold, Daliborka Nikolic, Andreas Seidel-Morgenstern, Achim Kienle1603



Steady-state Optimality Analysis of Mpc Controllers

Jozef Vargan, Jakub Puk, Karol Lubusk� , Miroslav Fikar1609



Seasonal Setpoints Optimization of Wwtp Do Control Based on Artificial Neural Networks Performance Indices Prediction

Norbert B. Mih�ly, Vasile M. Cristea1615



Adversarially Robust Real-time Optimization and Control with Adaptive Gaussian Process Learning

Akhil Ahmed, Antonio Del Rio Chanona, Mehmet Mercang�z1621



Online Process Monitoring Through Integration of Joint Recurrence Plot and Convolutional Neural Networks

Yiran Dong, Jie Zhang, Chris O'Malley1627



A Python Implementation of a Steady-state Real Time Optimization (srto) and Realtime Optimization with Persistent Adaptation (ropa)

Carlos C. Sanz, Galo A.C. Le Roux1633



Hierarchical Reinforcement Learning for Plantwide Control

Maximilian Bloor, Akhil Ahmed, Niki Kotecha, Calvin Tsay, Mehmet Mercang�z, Antonio Del Rio Chanona1639



Energy- and Process Real-time Optimization Through Hybrid Modeling a Case from Viking Malt A/s

Peter Jul-Rasmussen, Adem R.N. Aouichaoui, Maciej Korzepa, Kurt Engelbrecht, Katrine Kongsgaard, Jakob K. Huusom1645



A Milp Model for the Minimization of Cycle Time in Periodic Production Scheduling Using Flexible Operation Shifts

Georgios Georgiadis, Alexandros Koulouris1651



Nonlinear Dynamic Optimization for Gas Pipelines Operation

Lavinia Ghilardi, Sakshi Naik, Emanuele Martelli, Francesco Casella, Lorenz T. Biegler1657



Learning to Recycle Benders Cuts for Mixed Integer Model Predictive Control

Ilias Mitrai, Prodromos Daoutidis1663



Logical Processing of Sequential Alarms for Safer Plant Operation

Ryuto Tanaka, Masaru Noda1669



Design of a Predictive Functional Controller Based on Combination of Data-driven Tuning and Prediction Methods

Yoichiro Ashida, Masanobu Obika1675



Optimal Control of Industrial Solvent-based CO2 Capture Plants

Fredrik Gjertsen, Adriaen Verheyleweghen, Svein Olav Hauger, Vemund Tjessem, Thor Mejdell, Hanne M. Kvamsdal1681



A Novel Hydrogen-based Desalination System for a Self-sustaining Community

Du Wen1687



Machine Learning-based Soft Sensor for a Sugar Factory’s Batch Crystallizer

Mohammad Reza Boskabadi, Abhishek Sivaram, G�rkan Sin, Seyed Soheil Mansouri1693



Handling Nonlinearities and Uncertainties of Fed-batch Cultivations with Difference of Convex Functions Tube Mpc

Niels Krausch, Martin Doff-Sotta, Mark Canon, Peter Neubauer, Mariano Nicol�s Cruz-Bournazou1699



Optimal Feed Scheduling and Co-digestion for Anaerobic Digestion Sites with Dynamic Demands

Meshkat Dolat, Rohit Murali, Ruosi Zhang, Mohammadamin Zarei, Duo Zhang, Dongda Zhang, Jhuma Sadhukhan, Michael Short1705



Digital Twins for Process Monitoring and Anomaly Detection

Anziel Malandri, Mehmet Mercang�z1711



An Implementable Zone-based Nmpc with Echo State Networks Applied to an Esp-lifted Oil Well for Maximum Oil Production

Odilon S.L. De Abreu, Marcos Pellegrini Ribeiro, Bernardo Pereira Foresti, Leizer Schnitman, M�rcio A.F. Martins1717



Ribbon Splitting in Roller Compaction and Monitoring of a Dry Granulation Process

David Sixon, Josie Kirsch, Adam Georgopoulos, Rexonni Lagare, Marcial Gonzalez, Zoltan Nagy, Gintaras Reklaitis1723



A Deep Reinforcement Learning Pi Tuning Strategy for Closed-loop Operation of a Recirculating Aquaculture System

Hao Wang, Luis Ricardez-Sandoval1729



A Prediction Error Adaptive Kalman Filter for On-line Spectral Measurement Correction and Concentration Estimation

Daniel Sbarbaro, Tor Arne Johansen, Jorge Ya�ez1735



Novel Panoramic Indicators for Process Operation Stability Assessment through Clustering and Frequency Analysis

Tetsuya Wada, Yoshiyuki Yamashita1741



Industrial Ep(d)m Polymerization Reactor Simulation: Process Dynamics and Control

Franco Scaglia, Giovanni Regattieri, Gianni Marchetti1747



Low Concentrated P- and K-based Fertilizers for Localized Agricultural Supply Chains

Brenno C. Menezes, Matheus Duarte, Caiubi Kuhn, Ana Gomes, Mohammed Yaqot, Kim Moloney1753



Experimental Implementation of an Economic Model Predictive Control for Froth Flotation

Paulina Quintanilla, Daniel Navia, Stephen Neethling, Pablo Brito-Parada1759



Ethanol Increase in Gasoline and Its Impacts in Manufacturing and Supply Chains

Mahmoud Ahmednooh, Brenno C. Menezes1765



Optimal Flexible Operation of an Aicr for P2a

Joachim Weel Rosbo, Anker D. Jensen, John Bagterp J�rgensen, Jakob K. Huusom1771



Optimization of Biomass-to-green Methanol Production: Techno-economic and Environmental Analysis

Chanmok Kim, Chanhee You, Hyeon Yang, Jiyong Kim1777



A Reinforcement Learning Framework for Online Batch Process Scheduling

Syu-Ning Johnn, Vassilis M. Charitopoulos1783



Role of the Throughput Manipulator on Economic and Sustainable Process Operation

Aayush Gupta, Prakhar Srivastava, Nitin Kaistha1789



Integrated Urban Energy System for Metropolitan Area: Optimization and Sensitivity Analysis

Mohammadamin Zarei, Meshkat Dolat, Chul-Jin Lee, Michael Short1795



Learning Based Adaptive Robust Control of a Precipitation Process

Sandesh Hiremath, Mikhail Kakanov, Andreas Voigt, Kai Sundmacher, Naim Bajcinca1801



Q-learning & Economic Nl-mpc for Continuous Biomass Fermentation

Tom Vinestock, Hak-Keung Lam, Mark Taylor, Miao Guo1807



Development of an Inferential Control System of Hydrogen Concentration of Exhaust Gas in Fuel Cell Systems

Taisei Izawa, Sanghong Kim, Miyuki Matsumoto, Shigeki Hasegawa, Motoaki Kawase1813



Advancing Liquid Level Recognition: a Combined Deep Learning and Pixel Manipulation Approach

Borui Yang, Jinsong Zhao1819



Inventory Strategies for Optimizing Resiliency and Sustainability in Pharmaceutical Supply Chains a Simulation-optimization Approach

Catarina M. Marques, Ana Carolina Silva, Jorge Pinho De Sousa1825



Big Data Analytics for Advanced Fault Detection in Wastewater Treatment Plants

Morteza Zadkarami, Krist V. Gernaey, Ali Akbar Safavi, Pedram Ramin1831



Multiphase Compartment Modelling and Systems Identification of a U-loop Reactor for Continuous Single Cell Protein Production

Johan Le Nepvou De Carfort, Tiago Pinto, Ulrich Kr�hne1837



Predicting the Coagulation Potential of Waste Lubricant Oil (wlo) Using Multiblock Machine Learning of Nir and Mir Spectroscopy

Ruben Gariso, Tiago J. Rato, Margarida J. Quina, Licinio Ferreira, Marco S. Reis1843



Multi-source Transfer Learning for Chemical Process Fault Diagnosis with Multi-channel Feature Extraction

Ruoshi Qin, Jinsong Zhao1849



Continuous-time Formulation of Integrated Crude Scheduling and Planning Operations for Petrochemical Sites

Lifeng Zhang, Congqin Ge, Yuxuan Xu, Zhihong Yuan1855



Implementation of Model Predictive Control into the Rigorous Simulator of the Fuel Cell System

Masanori Oshima, Sanghong Kim, Shigeki Hasegawa, Ibuki Sakata, Ken-Ichiro Sotowa, Motoaki Kawase1861



Neural Ordinary Differential Equations Auto-encoder for Fault Detection in Process Systems

Umang Goswami, Jyoti Rani, Hariprasad Kodamana1867



A Complete Pipeline for the Fusion of Multiple Heterogeneous Redundant Sources

Marco S. Reis, Eugeniu Strelet, Ivan Castillo, You Peng, Swee-Teng Chin1873



Optimal Operation of Vapor-recompressed Middle Vessel Batch Distillation

Surendra Beniwal, Sujit Jogwar1879



Heterogenous Electrolysis Plants as Enabler of Efficient and Flexible Power-to-x Value Chains

Michael Mock, Isabell Viedt, Hannes Lange, Leon Urbas1885



Enabling Load-flexible Ammonia Synthesis via Polytropic Fixed-bed Reactors

Lukas Gottheil, Jens Bremer1891



Causal-assisted Sequence Segmentation and Its Soft Sensing Application for Multiphase Industrial Processes

Yimeng He, Le Yao, Xiangyin Kong, Xinmin Zhang, Zhihuan Song, Manabu Kano1897



Csve: Enhancing Uncertainty Quantification in Industrial Kpi Prediction

Yiran Ma, Zhichao Chen, Xinmin Zhang, Zhihuan Song, Manabu Kano1903



Bilevel Optimization of Mixed-integer Nonlinear Integrated Planning and Scheduling Problems Using the Domino Framework

Hasan Nikkhah, Vassilis M. Charitopoulos, Styliani Avraamidou, Burcu Beykal1909



A Real-time Risk-based Optimization Framework for Safe and Smart Operations

Austin Braniff, Sahithi Srijana Akundi, Yuanxing Liu, Faisal Khan, Efstratios N. Pistikopoulos, Yuhe Tian1915



Flexible Relaxation Method for Infeasibility Diagnosis in the Optimization Model of Natural Gas Pipeline Network Sales Considering Component Self-consumption Gas

Xiaozheng Chen, Siyi Mi, Jiaming Guo, Dingzhi Liu, Xiaoyong Gao1921



Robust Stability Analysis of Koopman Based Mpc System

Gajanand Verma, William Heath, Constantinos Theodoropoulos1927



Boosted Ensemble Learning for Model Predictive Control with Reconfiguration of Modular Facilities

Yi Dai, Andrew Allman1933



Simulation-based Robust Model Predictive Control for N-dimensional Linear Multi-agent Systems with Uncertain and Heterogeneous Dynamics in Modular Plants

Helaleh Badrnoebashar, Anselm Klose, Jonathan M�dler, Leon Urbas1939



Causality-driven Dynamic Scheduling of Multipurpose Batch Plants

Taicheng Zheng, Dan Li, Jie Li1945



Assessment of Parameter Uncertainty in the Maintenance Scheduling of Reverse Osmosis Networks via a Multistage Optimal Control Reformulation

Bogdan Dorneanu, Mina Keykha, Harvey Arellano-Garcia1951



Multistage Optimal Control and Nonlinear Programming Formulation for Automated Control Loop Selection

Vasileios Mappas, Bogdan Dorneanu, Vassilios S. Vassiliadis, Harvey Arellano-Garcia1957



Deep Neural Networks-based Fault Diagnosis Model for Process Systems

Mohammad Shahab, Zoltan Nagy, Gintaras Reklaitis1963



Enhancing Human Operators Trust in Mpc Controllers Through an Explainable Ai Methodology

Anurag Pathak, Babji Srinivasan, Rajagopalan Srinivasan1969



Coupling Electrodialysis with Bipolar Membranes with Renewable Energies Through Advanced Control Strategies

Calogero Cassaro, Giovanni Virruso, Andrea Cipollina, Adriano Fagiolini, Alessandro Tamburini, Giorgio Micale1975



Real-time Optimization with Machine Learning Models and Distributed Modifier Adaptation Applied to the Mdi-process

Jens Ehlhardt, Inga Wolf, Sebastian Engell1981



Model Predictive Control Strategies for Continuous Manufacturing Processes

Ioana Nascu, Nikolaos A. Diangelakis, Mircea ?u?ca, Vlad Mihaly, Zoltan Nagy1987



Integration of Real-time Optimization and Model-predictive Control: Application to Refinery Diesel Pool

Pelin Dologlu, A. Eren Vedin, Ridvan Memis, Sadik �demis, Kemal Bur�ak Kaplan, Shaig Goyushov, Mehran Isgandarli1993



An Milp Based-approach to Logistics of Air Separation Supply Chains with a Heterogeneous Fleet of Trucks

Sergio G. Bonino, Luis J. Zeballos, Akash Moolya, Jose Lainez, Jose M. Pinto, Ignacio E. Grossmann, Carlos A Mendez1999



Market-oriented Decision Making in Power Generation Investment

Maria Kanta, Evangelos G. Tsimopoulos, Christos N. Dimitriadis, Michael C. Georgiadis2005



An Optimization Model for the Maximization of Crop Productivity, Biodiversity, and Ecosystem Services

Caleb H. Geissler, Christos T. Maravelias2011



Solar-driven Calcium Looping Cycle for Time-flexible Carbon-free Power Generation with Thermochemical Energy Storage Capability

Calin-Cristian Cormos, Letitia Petrescu, Ana-Maria Cormos, Simion Dragan2017



Model-based Techno-economic Analysis for Integrated Synthetic Natural Gas Production System Using Atmospheric CO2 Captured by Metal Organic Framework Adsorbent

Hideki Harada, Anshuman Sinha, Tomoyuki Yajima, Yoshiaki Kawajiri2023



Tdes: Transformation of the Dutch Energy System

Jan Van Schijndel, Rutger De Mare, Nort Thijssen, Jim Van Der Valk Bouman2029



Integrated Design and Location of a Green Hydrogen Production Chain from Waste Biomass. a Case Study in Western Andalusia.

Silvia Moreno, Laura R. Pi�eiro, Alicia Ronda, Bernab� A. Fari�as, Pedro Haro2035



Switching from Fossil Fuel-based to Concentrated Solar Power Driven Tri-generation Systems: an Optimization Model

Rachid Klaimi, Sabla Y. Alnouri, Mirko Stijepovic2041



Energetic Comparison of Electrochemical Versus Mechanical Compression of Hydrogen

Georgia Ioanna Prokopou, Matthias Leon M�dden, Alexander Mitsos, Dominik Bongartz2047



A Simulation-based Approach for Energy-flexible Scheduling of Integrated Energy Process Systems

R. Michael Kalpage, Wei Yu, Martin Atkins, Brent Young2053



Towards Environmentally Sustainable Production of Diphenyl Carbonate: Comparative Analysis of Alternative Pathways

Tsai-Wei Wu, Alexander Guzman-Urbina, Hajime Ohno, Yasuhiro Fukushima2059



A Simulation-based Integration of Carbon Capture and Utilization in a Urea Production Process

Christopher Varela, Fernando Zea, Oris Correa, Kyle V. Camarda2065



Innovative Structure of a Liquefied Natural Gas (lng) Process by Mixed Fluid Cascade Using Solar Renewable Energy, Photovoltaic Panels (pv), and Absorption Refrigeration System

Masoud Taghavi, Ha-Jun Yoon, Jung-Ung Choi, Chul-Jin Lee2071



Techno-economical Evaluation and Comparison of Various CO2 Transportation Pathways

Mustafa Cakartas, Jianzhao Zhou, Jingzheng Ren, Anders Andreasen, Haoshui Yu2077



Integrated Modelling of Concentrated Solar Power Plants Networks: Electricity Production, Storage, Conversion and Distribution in Spain

Jos� A. Luce�o S�nchez, Mariano Martin, Sandro Macchietto2083



A Novel Optimisation Framework to Design Market-based Policy Interventions for the Uptake of Alternative Fuels in the Uk Chemical Industry

Gbemi Oluleye, Devan Patel, Pauline Matalon, Elisabeth Maya Rosa2089



Integration of Process and Working-fluid Design for Combined Heating and Power (chp) Systems

Andres Pina-Martinez, Romain Privat, Jean-Fran�ois Portha, Jean-Marc Commenge2095



Multi-period Stochastic Optimization of Integrating Carbon Capture and Storage/utilization (ccs/ccu) for Cement Industry

Pingping Wang, Stavros Papadokonstantakis2101



Mmc Rectifier as an Interface for Sustainable Energies Sources on Mtdc Grids

Guillermo Adolfo Anaya-Ruiz, Pascual Eduardo Murillo-Alvarado, Alejandra Guadalupe Andrade-Partida, Gabriela Guadalupe Esquivel-Barajas, Rogelio Gudi�o-Valdez, Daniel Miranda-Carrasco2107



Multi-objective Optimization Applied to the Thermal Hydrolysis and Anaerobic Digestion System for Biosludge from the Pulp Kraft Industry

Nicolas Goycoechea, Liliana Borzacconi, Jimena Ferreira, Martin Pedemonte, Ivan Lopez2113



Evaluation of Energy Requirements for Chemicals and Fuels Manufactured via Electrochemical Reduction of Carbon Dioxide

Riccardo Dal Mas, Ana Somoza-Tornos, Anton A. Kiss2119



Process Simulation of Beccs-to-x: Investigating the Potential of Hydrogen and Sustainable Aviation Fuel Production

Mathew Dennis Wilkes, Solomon Brown2125



Exergo-techno-economic Comparison of Power&biomass-to-kerosene Pathways

Simone Mucci, Dominik P. Goldstein, Dominik Bongartz, Alexander Mitsos2131



Design of Carbon Neutral Methanol Production via Integration of Renewable Hydrogen and Dry Reforming Process

Mahmoud Abdalla, Mohammed G. Mohammed, Umer Zahid2137



Conceptual Design of a Large Ship Propulsion System Fueled by an Ammonia-hydrogen Blend: Toward a Decarbonized Shipping Transport

Antonio Sanchez, M.A. Martin Rengel, Mariano Martin2143



Alternative Pathways to Sustainable Aviation Fuel from CO2 and H2: an Enviro-economic Assessment

Andrea Bernardi, David Danaci, Andrew Symes, Beno�t Chachuat2149



Multi-objective Optimization of the Renewable Methanol for a Defossilized Production

Javier Fernandez-Gonz�lez, Marta Rumayor, Jara Laso-Cortabitarte, Antonio Dominguez-Ramos, Angel Irabien, Ignacio E. Grossmann2155



Global Optimization via Quadratic Disjunctive Programming for Water Networks Design with Energy Recovery

Carolina Tristan, Marcos Fallanza, Raquel Ib��ez, Ignacio E. Grossmann, David E. Bernal Neira2161



A Model Development and Sensitivity Analysis of a Multitubular Thermochemical Recovery for Internal Combustion Engine Exhaust Heat

Victor E. Morales-Olmedo, Ricardo Morales-Rodriguez, Jesus I. Minchaca-Mojica, Ignacio R. Galindo-Esquivel2167



Optimization-based Framework for Techno-economic and Environmental Assessment of CO2 Capture, Utilization, and Storage Strategies

Chanhee You, Chanmok Kim, Hyeon Yang, Jiyong Kim2173



Systematic Analysis of Energy Transition Pathways for Emission Reduction in the Flat Glass Industry Using Milp Formulation

Muhammad Salman, Daniel Florez-Orrego, Juan Correa-Laguna, Fran�ois Marechal, Gr�goire L�onard2179



Harvesting the Wind Assessment of Offshore Electricity Storage Systems

Jan F. Wiegner, Inge M. Ossentjuk, Robbert M. Nienhuis, Antonis I. Vakis, Madeleine Gibescu, Matteo Gazzani2185



Power System Planning Integrating Hydrogen and Ammonia Pathways under Uncertainty

Georgios L. Bounitsis, Vassilis M. Charitopoulos2191



Prospective Lifecycle Design Through Process Modeling of Energy Recovery from Waste Plastics

Shoma Fujii, Yuichiro Kanematsu, Yasunori Kikuchi2197



Techno-economic and Environmental Sustainability Assessment of Rice Straw-based Bioenergy with Carbon Capture and Utilization

Ryan Macalino, Jhud Mikhail Aberilla2203



Surrogate Based Mixed Integer Linear Programming Model for Decarbonization of an Integrated Gas-oil Separation Network

Abdullah Bahamdan, Nilay Shah, Antonio Del Rio Chanona2209



Using CFD to Calculate the Heat Transfer Effectiveness of a Particle Curtain Heat Transfer Device for an Atmospheric Pressure Gas with High Effectiveness and Extremely Low Pressure Drop

Marko Trifunovic, Mark Latham, Andrew Hoadley, David Frederick Fletcher, Caecilia Potter2215



Scale-bridging Optimization Framework for Desalination Integrated Produced Water Networks

Sakshi Naik, Miguel Zamarripa, Markus Drouven, Lorenz T. Biegler2221



Electrification in the Petrochemical Industry: Can Flexibility Enable Low-carbon Utility Systems?

Svenja Bielefeld, Milos Cvetkovic, Andrea Ram�rez Ram�rez2227



An Efficient Ems for Aggregated Energy Systems Including Renewables, Storages, Chp Units and Heat Pumps

Filip Sobic, Lavinia Ghilardi, Hilal Bahlawan, Lapo Cheli, Alessandro Innocenti, Emanuele Martelli2233



Electric Heat Pumps and Combined Heat and Power Systems for the Optimal Decarbonisation of the Integrated Uk Energy System

Matthias Mersch, Andreas V. Olympios, Christos N. Markides, Niall Mac Dowell2239



Economic Analysis of Liquid Air Energy Storage Systems

Shaylin A. Cetegen, Truls Gundersen, Paul I. Barton2245



Prospective Life-cycle Design of Regional Resource Circulation Applying Technology Assessments Supported by Cape Tools

Yasunori Kikuchi, Hideaki Kurishima, Yuichiro Kanematsu, Takuya Kasai, Shoma Fujii, Yuko Oshita, Tetsuya Ishida, Satoshi Ohara2251



Hydrogen Strategic Planning for Heat Decarbonisation under Uncertainty

Margarita E. Efthymiadou, Vassilis M. Charitopoulos, Lazaros G. Papageorgiou2257



A Solar and Wind Energy-based Biomass-to-methanol System with Coupling of Different Electrolyzers

Guanxin Xu, Yan Wu, Yufei Wang, Xiao Feng2263



Municipal Solid Waste Treatment Processes: Identification and Comparison of Performance Indicators

Julia P. Oliveira, Ana Mehl, Argimiro R. Secchi, Flavia C. Alves2269



A Data Visualization Tool for Biomass Valorization in Brazil

Roger Sampaio Bif, Larissa Thais Bruschi, Mois�s Teles Dos Santos2275



Evaluation of Different Water Sources for Electrolysis: a Study Case of the Priority Regions for Green Hydrogen Production in the State of Bahia

Leonardo O.S. Santana, Gustavo S. dos Santos, Chrislaine B. Marinho, Artur S. Bispo, Jose Almeida, Fernando L.P. Pessoa2281



Design of a Reverse Supply Chain Network for Photovoltaic Panels

Funda Iseri, Halil Iseri, Natasha J. Chrisandina, Shivam Vedant, Eleftherios Iakovou, Efstratios N. Pistikopoulos2287



Determining Competition Between Lca Environmental Impact Categories Through Milp Single Objective Optimization a Case Study on Green Hydrogen

Diego Larrahondo Chavez, Catherine Azzaro-Pantel, Florent Montignac, Alain Ruby2293



Solving Combined Sizing and Dispatch of Pv and Battery Storage for a Microgrid Using Admm

Robert Steven, Oleksiy Klymenko, Michael Short2299



Screening of Solvents for Perovskite Solar Cells Using Reverse Engineering Approach

Luis Eduardo Ramirez Cardenas, Rachid Ouaret, Lea Schwersenz, Vincent Gerbaud, Markus Kohlstadt, Sophie Thiebaud-Roux, Ivonne Rodriguez-Donis2305



Towards CO2 Reduction in Middle East: a Techno-environmental Assessment

Nasser Al-Malki, Mohammed Yaqot, Brenno C. Menezes2311



Multiscale Modeling of Solid Oxide Fuel Cells Using Various Microscale Domains Across the Length of the Cell

Hamid Reza Abbasi, Masoud Babaei, Constantinos Theodoropoulos2317



Sustainable Transformation of Polystyrene Waste Through Pyrolysis

Maria V. Colombo, Jorge A. Ressia, Alejandra S. Diez, Patricia M. Hoch2323



Wine Effluents Valorization Through a Biorefinery Scheme

Carlos Eduardo Guzm�n Mart�nez, Araceli Guadalupe Romero Izquierdo, Sergio Iv�n Mart�nez Guido, Salvador Hern�ndez, Claudia Guti�rrez-Antonio2329



Circular Economy Assessment of Viable for Fuels for Mobility

Kenneth Martinez, Paola Munoz-Briones, Styliani Avraamidou2335



Optimum Green Clean Water Solution for Remote Islands

Aggelos Kaldellis, Christofis Koroneos, Emilia Kondili, John K. Kaldellis2341



A Novel Vapor Recompressed Batch Extractive Distillation for Ethanol Dehydration

Sidharth Sankar Parhi, Gade Pandu Rangaiah, Amiya K Jana2347



Optimal Design Supply Chain for Agricultural Waste-based Biofuels

Dulce Maria Aguilar-Murgu�a, Sergio Ivan Martinez-Guido, Claudia Guti�rrez-Antonio, Salvador Hern�ndez2353



Performance Assessment of Waste and Biomass Two-stage Pyrolysis/split Product Oxy-gasification (pspog) Using Aspen Simulation

Juma Haydary2359



Green Hydrogen Production from Solar-powered Electrolysis: a Novel Optimization Methodology

Andrea Isella, Davide Manca2365



Estimating the Potential of Sustainable Aviation Fuel Enabled Aviation Decarbonization in China: an Integrated Resource-technology-economy-environment Analysis Framework

Wubin Yan, Fangwei Cheng, Xiaonan Wang, Chuan Zhang2371



Dynamic Simulation and Optimisation of Water and Energy Consumption in a Ceramic Plant: Application of the Customised Thermwatt Computational Tool

Miguel Castro Oliveira, Rita Castro Oliveira, Henrique A. Matos2377



Pioneer Options for Sustainable Energy Storage: a Comparative Study of 25 Alternatives Using Data Envelopment Analysis

Fatemeh Rostami, Richard Cabrera, Laureano Jimenez, Carlos Pozo2383



Comparing the Sustainability Level of Biofuels with Data Envelopment Analysis

Richard Cabrera, Fatemeh Rostami, Laureano Jimenez, Carlos Pozo2389



A Multi-parametric Optimization Approach for Bi-level Decision-making Strategies in Energy-water Nexus Supply Systems

Elizabeth J. Abraham, Marcello Di Martino, Dustin Kenefake, Dhabia M. Al-Mohannadi, Efstratios N. Pistikopoulos2395



A Systematic Analysis of Economic and Environmental Trade-offs in Hydrogen Supply Chains with Resilience Considerations

Yasir Ibrahim, Elizabeth J. Abraham, Dhabia M. Al-Mohannadi2401



Sustainability Analysis of a Large-scale Calcium Looping Plant Coupled with Concentrated Solar Energy

Ricardo N. Dias, Rui M. Filipe, Carla I.C. Pinheiro, Henrique A. Matos2407



Real Time Optimization of Sour Gas Processing Unit via Sulfur Dioxide Emissions Predictive Model

A. Eren Vedin, Pelin Dologlu, Mert Akcin, Aygul Karimova, Kemal Bur�ak Kaplan, Aysegul Sener, Osman Karan2413



Design and Planning Green Hydrogen Supply Chains: Characterization and Optimization

Filipa Braz Silva, C�tia da Silva, Ana Paula Barbosa-Povoa2419



Life Cycle Assessment (lca) of Dimethyl Ether (dme) Production: Fossil Fuels Vs. Biogas

Matteo Fedeli, Alessandro Di Pretoro, Ludovic Montastruc, Flavio Manenti2425



Computer-aided Drug Screening Based on the Binding Site Selectivity of Ace2: Machine Learning, Docking, and Molecular Dynamics Simulations

Xinhao Che, Qilei Liu, Fang Yu, Lei Zhang2431



Modelling Liver Preservation

Angelo Lucia, Korkut Uygun2437



Design of a Novel Pass-through Distillation Process for Bioethanol Recovery

Tamara Jankovic, Adrie J. J. Straathof, Ian R. Mcgregor, Anton A. Kiss2443



From Laboratory Scale to Innovative Spruce-based Biorefinery. Note I: Conceptual Process Design and Simulation

Filippo Bisotti, Matteo Gilardi, Olaf T. Berglihn, Roman Tschentscher, Line D. Hansen, Svein J. Horn, Aniko Varnai, Bernd Wittgens2449



Utilization of Solid Wastes to Satisfy Energy Requirements of Lng Process

Ahmed Al-Nouss, Gordon Mckay, Tareq Al-Ansari2455



Exploring Biorefinery Designs for Agricultural Waste with Stochastic Optimization

Lucas Van Der Hauwaert, Alberte Regueira, Miguel Mauricio Iglesias, Edwin Zondervan2461



Economic Feasibility of Thermochemical Conversion for Woody Biomass-derived Liquid Fuels in Spain

Usman Khan Jadoon, Ismael Diaz, Manuel Rodriguez2467



Towards Modelling of an Industrial Aspergillus Oryzae Aerobic Fed-batch Fermentation Process Process Characterization Across Scales

Mariana Albino, Carina L. Gargalo, Ulrich Kr�hne, Mads O. Alb�k, Gisela Nadal-Rey, Krist V. Gernaey2473



Assessment Techniques for Convergence and Degree of Freedom in Biologics Modeling

Tomoyuki Taguchi2479



Computer-aided Optimization of
cooling Temperature Profiles in Slow Freezing for
human Induced Pluripotent Stem Cells

Yusuke Hayashi, Yuki Uno, Masahiro Kino-Oka, Hirokazu Sugiyama2485



Bridging Weak Links in Mechanistic Modeling: Approach and Application in CHO Cell Cultivation for Mab Production

Kozue Okamura, Sara Badr, Hirokazu Sugiyama2491



Enhanced Kinetic Model Parameters for Xylitol Bioproduction from Candida Mogii Atcc 18364

Julio Cesar Sanchez-Rendon, Luis Geronimo Matallana, Ricardo Morales-Rodriguez, Oscar Andres Prado-Rubio2497



Improving the Production of Phbv in Cupriavidus necator by Optimal Control

Rudolph L. Kok, Rolf Findeisen, Achim Kienle, Stefanie Duvigneau2503



Mathematical Modelling of a Novel Mineral Carbonation System Based on Biological Ph Swing for Atmospheric CO2 Removal

Yukun Zhang, Aidong Yang2509



Dynamic Photo-mechanistic Modelling of Biomass Growth and Optical Density for the Cyanobacterium Synechococcus Sp. Pcc 11901

Bovinille Anye Cho, Jose Angel Moreno-Cabezuelo, Lauren A. Mills, Antonio Del Rio Chanona, David J. Lea-Smith, Dongda Zhang2515



Adjustable Robust Optimization with Mixed-integer Recourse for the Synthesis of Continuous Rufinamide Manufacturing Process

Taoyu Qiu, Wenhui Yang, Zhihong Yuan2521



Semi-mechanistic Modelling of Ionic Liquid-based Biomass Fractionation

Suhaib Nisar, Agnieszka Brandt-Talbot, Jason P. Hallett, Beno�t Chachuat2527



Climate Change Effect on Microbial Interactions Using Surrogate Modelling of an Individual-based Model

Lydia Katsini, Jian Wang, Ihab Hashem, Satyajeet S. Bhonsale, Jan F.M. Van Impe2533



Stochastic Extreme Pathway Generation in View of Metabolic Network Reduction

Wannes Mores, Satyajeet S. Bhonsale, Filip Logist, Jan F.M. Van Impe2539



Climate Change Threatens the Food Safety of the Supply Chain

Lydia Katsini, Satyajeet S. Bhonsale, Styliani Roufou, Sholeem Griffin, Vasilis Valdramidis, Simen Akkermans, Monika Polanska, Jan F.M. Van Impe2545



A Conceptual Design and Economic Assessment of a Chitin Biorefinery Based on Shrimp Processing Wastes

Ana Carolina Moreira Fonseca, Bruno Faccini Santoro, Omar Jos� Guerra Fern�ndez, Mois�s Teles Dos Santos2551



Parameter Estimation of Multi-substrate Biokinetic Models of Lignocellulosic Microbial Protein Systems

Mason Banks, Mark Taylor, Miao Guo2557



Sustainable Production and Scale-up of Succinic Acid from Cyanobacteria

Roja K, Yogendra Shastri2563



Minimal Target Indices for Cyanobacteria-based Biorefineries and Optimal Design of the Metabolic Network

Matias Ramos, Fernando Ramos, Romina Lasry Testa, Vanina Estrada, Maria Soledad Diaz2569



Use of Bioremediation System to Regenerate Wastewater from Shale Gas Production.

Ariadna Armendariz-Ortega, Antonio Espu�a, Sergio Medina-Gonz�lez2575



Onboard Or Onsite Hydrogen Production: a Comparative Investigation

Bruna Gava Floriam, Aulus R. Rom�o Bineli, Rubens Maciel Filho2581



Continuous Production of Recombinant Adeno-associated Viral Vectors via Transient Transfection of Hek293 Cells in Perfusion Bioreactor

Damdae Park, Tam N.T. Nguyen, Jos� Sangerman, Prasanna Srinivasan, Rui Wen Ou, Georgios Katsikis, Moo Sun Hong, Paul W. Barone, Caleb Neufeld, Jacqueline M. Wolfrum, Stacy L. Springs, Anthony J. Sinskey, Richard D. Braatz2587



Life Cycle Design of Bioprocess System Applying Simulation-based Approach

Satoshi Ohara, Yuichiro Kanematsu, Shoma Fujii, Yasunori Kikuchi2593



Use of Dynamic Flux Balance Analysis for Evaluation of the Poly-3-hydroxybutyrate Production Potential of Recombinant Escherichia Coli

Willians O. Santos, Rafael David De Oliveira, Jose Gregorio Cabrera Gomez, Galo A.C. Le Roux2599



Flow Phenomena in Renal Arteries with Partial Coverage After Aneurysm

Dhurjati Chakrabarti, Laura D. Edwards2605



Thermodynamic Approach to Simulate the Hydrodeoxygenation Process of Lignin

Aristide Giuliano, Aniello Di Giacomo, Nicola Pierro, Isabella De Bari, Diego Barletta2611



Second-generation Biorefinery Location Selection in Europe Using Satellite Data and Crop Calendars

Varun Punnathanam, Raunak Bardia, Shirish Potu, Nicole Elliott, Jose Maria Gonzalez Martinez2617



Exergoeconomical and Ecological Analysis of Biogas Valorization Pathways Comparing a Combined Heat & Power Plant with a Pressurized Water Process

Fizza Tahir, Burcu Aker, Sven Nater, Keren Djuffo Jiofack, Jens-Uwe Repke, Jan Sch�neberger2623



Improving Butanol and Acetone Production by Two-stage Fermentation Coupled with Flash Distillation

Juan C. Barreiro, Paula A. Tapias, Nicolas Mu�oz, Karoll M. Rubiano, Jose M. Bernal, Carlos A. M. Riascos2629



Economic Optimization of Intensified Processes to Produce Bioethanol from Lignocellulosic Biomass.

Yulissa M. Espinoza-V�zquez, Fernando Israel G�mez-Castro, Eduardo S�nchez-Ram�rez, Araceli Guadalupe Romero Izquierdo2635



Dynamic Simulation and Evaluation of Integrated Chromatography-ultrafiltration in Mab Production

Wil Jones, Dimitrios I. Gerogiorgis2641



Multi-objective Optimisation of an Integrated Cultivation-aggregation Model for Mab Production

Wil Jones, Dimitrios I. Gerogiorgis2647



From Laboratory Scale to Innovative Spruce-based Biorefinery. Note Ii: Preliminary Techno-economic Assessment

Matteo Gilardi, Filippo Bisotti, Olaf T. Berglihn, Roman Tschentscher, Line D. Hansen, Svein J. Horn, Aniko Varnai, Bernd Wittgens2653



Novel Process for Eco-efficient Production of Formic Acid by CO2 Hydrogenation

Maximiliano Taube, Amsalia Barus, Nikolaos Kalmoukidis, Savvas Staikos, Farzad Mousazadeh, Anton A. Kiss2659



Extracting and Ranking Metabolic Pathways from Large Metabolic Networks Using Graph Theory and Metabolic Flux Analysis

Konstantinos Mexis, Stefanos Xenios, Nikos Trokanas, Antonis Kokossis2665



Intimately Coupled Photocatalysis and Biodegradation Hybrid Systems in Tetracycline Removal

Rachel Mugumo, Shepherd M. Tichapondwa, Evans M.N. Chirwa2671



Data-driven Process Variable Prediction Using Augmented Orthogonal Autoencoder

Junqing Xia, Yoshiyuki Yamashita2677



Combining Automated Machine Learning and Molecular Simulation to Advance the Discovery of Cof-based Membranes for Acid Gas Separation

Bingru Xin, Minggao Feng, Min Cheng, Zhongde Dai, Li Zhou, Yiyang Dai, Xu Ji2683



Prediction Method for Reaction Yield of Deuteration of Polyfluoroperylene Using Generative Ai Techniques

Kazuhiro Takeda, Naoya Ohtsuka, Toshiyasu Suzuki, Norie Momiyama2689



Enhancing Fault Identification in Chemical Plants: a Multimodal Approach Combining Cnn and Continuous Wavelet Transform

Chinatsu Ukawa, Yoshiyuki Yamashita2695



A Symbolic Regression Based Methodology for the Construction of Interpretable and Predictive Thermodynamic Models

Sam Kay, Edgar I. Sanchez Medina, Kai Sundmacher, Dongda Zhang2701



Investigating the Reliability and Interpretability of State-of-the-art Machine Learning Frameworks for Chemical Retrosynthesis

Friedrich Hastedt, Klaus Hellgardt, Sophia Yaliraki, Antonio Del Rio Chanona, Dongda Zhang2707



Application of Artificial Neural Networks in Predicting the Operational Behavior of an Indirect Freezing Desalination System

Caio Francescato Dos Santos, Flavio Vasconcelos da Silva2713



Towards Sustainable Wwtp Operations: Forecasting Energy Consumption with Explainable Disentangled Graph Convolutional Networks

Louis Allen, Joan Cordiner2719



Reverse Hazop: Enhancing Safety Improvements Through Natural Language Processing and Text Mining

Seyed Mojtaba Hoseyni, Weixiang Han, Joan Cordiner2725



Developing Purely Data-driven Multi-mode Process Controllers Using Inverse Reinforcement Learning

Runze Lin, Junghui Chen, Biao Huang, Lei Xie, Hongye Su2731



Finding Advanced Mofs to Capture Argon from the Air Through Machine-learning and Molecular Simulation

Xiaoyi Xu, Xu Ji, Yiyang Dai2737



Digital Twins of Waste Particles for Waste Bulk Simulations

Karim Khodier, Alisa Rizvan2743



Improved Deep Learning Architectures for the Decomposition of Mixed Integer Optimization Problems

Niki Triantafyllou, Maria M. Papathanasiou2749



Data-driven Modeling for Industrial Plants Based on Non-stationary and Sparsely Sampled Data Streams

Changrui Xie, Yujie Hu, Lingyu Zhu, Han Gong, Hongyang Li, Xi Chen2755



Adaptive Soft-sensor for Sudden Changes in Process Characteristics Based on Transfer Learning

Kaito Katayama, Kazuki Yamamoto, Koichi Fujiwara2761



Non-parametric Models for Yield Prediction in a Suzuki-miyaura Coupling

Pablo J. Salazar, Brahim Benyahia2767



Learning Interpretable Representation of Koopman Operator for Non-linear Dynamics

Deepak Kumar, Vinayak Dixit, Manojkumar Ramteke, Hariprasad Kodamana2773



Enhancing Real-time Data Querying in Chemical Engineering: a Bilevel Vocabulary-constrained Seq2seq Approach

Zeheng Zhao, Jinsong Zhao2779



Long-term Constant Relation Analysis of Variables Based on Bayesian Optimization and Ssa and Application to the Monitoring of Non-stationary Process

Jingzhi Rao, Chengyu Han, Chong Liu, Wei Sun, Jingde Wang2785



Flexibility Analysis Using Surrogate Models Generated via Symbolic Regression

Tim Forster, Daniel Vazquez, Isabela Fons Moreno-Palancas, Gonzalo Guillen-Gosalbez2791



Predicting Fts Products Through Artificial Neural Network Modelling

Federico Moretta, Arian Grainca, Flavio Manenti, Giulia Bozzano, Carlo Pirola2797



Automated Reaction Mechanism Constructor

Miguel Angel De Carvalho Servia, King Kuok (Mimi) Hii, Klaus Hellgardt, Dongda Zhang, Antonio Del Rio Chanona2803



Integrating Knowledge-guided Symbolic Regression for Model-based Design of Experiments to Automate Process Flow Diagram Development

Alexander W. Rogers, Amanda Lane, Philip Martin, Dongda Zhang2809



Harnessing Instruction-tuned Large Language Models to Mine Structured Omics Data for Predicting Chemical Toxicity

Yufan Liu, Guoping Lian, Tao Chen2815



Achieving Flexibility in High Throughput Liquid Handing Experimentation by Smart System Design

Simon Seidel, Peter Neubauer, Mariano Nicol�s Cruz-Bournazou2821



Modelling and Stochastic Optimization of a Three-compartment Electrochemical Reactor for CO2 Electroreduction to Formic Acid Using Neural Networks

Jose Antonio Abarca, Mario Coz-Cruz, Guillermo Diaz-Sainz, Angel Irabien2827



Towards Self-consistent Graph Neural Networks for Predicting the Ideal Gas Heat Capacity, Enthalpy, and Entropy

Adem R.N. Aouichaoui, Simon M�ller, Jens Abildskov2833



Prototype of Automated Physical Model Builder: Challenges and Opportunities

Shota Kato, Manabu Kano2839



A Deep Reinforcement Learning Approach to Slug Flow Control in Oil and Gas Applications

Jos� R.T. Neto, Bruno D.O. Capron, Argimiro R. Secchi, Antonio Del Rio Chanona2845



Bioprocess Control: a Shift in Methodology Towards Reinforcement Learning

Mariana Monteiro, Cleo Kontoravdi2851



From Data to Alarms: Data-driven Anomaly Detection Techniques in Industrial Settings

Rastislav Faber, Martin Mojto, Karol Lubusk� , Radoslav Paulen2857



Machine Learning Models Development for the Optimal Production of Aligned Nanofibers

Francisco Javier Lopez-Flores, Jorge Andres Ornelas-Guillen, Alejandra Perez-Nava, Janett Betzabe Gonzalez-Campos, Jos� Maria Ponce-Ortega2863



Digital Twins in Operation: the Role of Robust Surrogate Modelling

Isaac Severinsen, Wei Yu, Timothy Gordon Walmsley, Brent Young2869



Data-driven Diagnostics of Variability During Changeover in Biopharmaceutical Freeze-drying

Gianluca Lombardini, Mohamed Rami Gaddem, Stephanie Knueppel, Sara Badr, Hirokazu Sugiyama2875



Machine Learning Enabled Life Cycle Assessment for Early-stage Sustainable Process Design

Kirti M. Yenkie, Emmanuel A. Aboagye, Austin L. Lehr, John Pazik, Jared Longo, Robert P. Hesketh2881



Personalized Supply Chain Solutions for Sustainable Fashion: Leveraging Social Media Insights and Machine Learning

Sarah Hassaan, Sumaya A. Rahman, Roberto Baldacci, Brenno C. Menezes2887



Integrated Energy-water Assessment Framework for Calcium Deficiency Control in Agricultural Greenhouses: a Data-driven Model Predictive Control Approach

Ikhlas Ghiat, Farhat Mahmood, Rajesh Govindan, Tareq Al-Ansari2893



Delving Into Machine Learning Modeling of Catalytic Reactor System: a Case Study of Steam Methane Reforming

Hyeon Yang, Chanhee You, Chanmok Kim, Jiyong Kim2899



Hierarchical Deep Reinforcement Learning for Hydrogen Supply Chain Management

Geunseo Song, Vahid Khaligh, J. Jay Liu, Jonggeol Na2905



An Integrated Framework: Inverse Design for Optimal Amine Solvent Using Reinforcement Learning and Enhanced CO2 Chemical Absorption Processes

Youhyun Kim, Haeyeon Choi, Damdae Park, Kyeongsu Kim, Jonggeol Na2911



Ml-based Automated Systems Identification: a Demonstration for Complex Chemical Processes

Robin Hofmann, Thomas Gr�tzner, Isuru Udugama, Christoph Bayer2917



Hyperparameter Optimization of Matheuristics for Hoist Scheduling

Sophie Hildebrandt, Guido Sand2923



Trbo: Transfer Learning Accelerated Bayesian Optimization

Haoyang Hu, Runzhe Liang, Zhihong Yuan2929



Estimation of Long-term Power Demand of Oil and Gas Installations Using Hybrid Models

Leif Erik Andersson, Adriana Reyes-Lua, Heiner Sch�mann, Brage Rugstad Knudsen2935



An Economic Assessment Framework for Intelligent Process Monitoring Systems

Fangyuan Ma, Cheng Ji, Jingde Wang, Nan Zhang, Wei Sun2941



Data-driven Discovery of Reaction Kinetic Models in Dynamic Plug Flow Reactors Using Symbolic Regression

Ben Cohen, Burcu Beykal, George M. Bollas2947



Hybrid Machine Learning for Scale-up of Biomass Production Using Photobioreactors

Abhishek Sivaram, Alireza Mehrdadfar, Lara Greco, Christian Euler, Seyed Soheil Mansouri2953



Correlating the Partitioning of Organic Molecules Between Water and [meoempyrr]+[fap]- Through Machine Learning

Flora Esposito, Ulderico Di Caprio, Florence Vermeire, Mumin Enis Leblebici2959



Industrial Data Science for Batch Manufacturing

Mattia Vallerio, Carlos Perez-Galvan, Fransisco J. Navarro-Brull2965



Automation of Experimental Workflows for High Throughput Robotic Cultivations

Lucas Kaspersetz, Fabian Schr�der-Kleeberg, Federico M. Mione, Ernesto C. Martinez, Peter Neubauer, Mariano Nicol�s Cruz-Bournazou2971



Optimisation of a Production Chain for Active Corrosion Protection via Digitalisation

Peter Klein, Heinz A. Preisig, Thomas F. Hagelien, Natalia Konchakova2977



Fault Detection and Analysis via Latent Space Differences Between the Plant and the Model Representing Normal Operation

Enrique Luna Villagomez, Hamidreza Mahyar, Vladimir Mahalec2983



Dynamic Scheduling of Ethylene Cracking Furnaces System Leveraging Deep Reinforcement Learning

Haoran Li, Yixin Wei, Tong Qiu2989



Towards Intelligent Wastewater Treatment: Prediction of Biodegradation Processes Through the Application of Machine Learning

Jiayuan Ji, Xinwu Zhou, Yuichiro Kanematsu, Yasunori Kikuchi2995



An Efficient Approach for Droplet Coalescence Videos Processing Based on Instance Segmentation and Multi-object Tracking Algorithms

Wenle Xu, Shuyuan Zhang, Kai Wang, Tong Qiu3001



Comparison of Different Data and Information Fusion Methods to Improve the Performance of Machine Learning Models

P�l P. Hanzelik, Alex Kummer, M�rton M�cz, Szilveszter Gergely, Dori�n L. Galata, Janos Abonyi3007



Reliable Data-driven Soft Sensor Modeling with the Aid of Stable Loss Function and Sample Graph

Ruikun Zhai, Jinchuan Qian, Xiaoyu Jiang, Xinmin Zhang, Zhihuan Song, Manabu Kano3013



Industrial Edge Mlops: Overview and Challenges

Fatima Rani, Nicolas Chollet, Lucas Vogt, Leon Urbas3019



Operationalization Management: Enhancing Life Cycle Management of Digital Twins

Bal�zs Palotai, �gnes B�rk�nyi, Gabor Kis, Janos Abonyi3025



Multi-objective Reinforcement Learning for Self- Optimization of Flow Chemistry

Ashish Yewale, Yihui Yang, Neda Nazemifard, Charles D. Papageorgiou, Chris D. Rielly, Brahim Benyahia3031



Combining Predictive Models and Reinforcement Learning for Tailored Molecule Generation

Miriam Nnadili, Andrew N. Okafor, David Akinpelu, Teslim Olayiwola, Jose Romagnoli3037



Deep Learning for Fast Inference of Mechanistic Models’ Parameters

Maxim Borisyak, Stefan Born, Peter Neubauer, Mariano Nicol�s Cruz-Bournazou3043



Automation in Port Areas and Industry for Safe and Effective Management of Dangerous Goods

Tomaso Vairo, Margherita Pettinato, Evgeniia Taubert, Ahmad M. Tahir, Bruno Fabiano3049



Data Augmentation Scheme for Raman Spectra with Highly Correlated Annotations

Christoph Lange, Isabel Thiele, Lara Santolin, Sebastian L. Riedel, Maxim Borisyak, Peter Neubauer, Mariano Nicol�s Cruz-Bournazou3055



Dl Based Real-time Prediction of Product Formation in Biopharmaceutical Manufacturing

Md Nasre Alam, Sami Ullah Bhat, Hariprasad Kodamana, Anurag S. Rathore3061



Adaptive Physics-informed Neural Network for Prediction with Evolving Process Parameters

Devavrat Thosar, Abhijit Bhakte, Zukui Li, Arvind Rajendran, Rajagopalan Srinivasan, Vinay Prasad3067



Potential for Counterfactual Explanations to Support Digitalized Plant Operations

Abhijit Bhakte, Rajagopalan Srinivasan3073



Understanding Cognitive Behavior in Collaborative Control Rooms Through Eye Tracking

Haider Altaf, Jhareswar Maiti, Babji Srinivasan, Rajagopalan Srinivasan3079



A Data-driven Approach for Constructing the Prediction Bounds on the Output Variables Using a Modified Loss Function and Analysing Information Retained During Development of the Model

Waqar Muhammad Ashraf, Vivek Dua3085



Enhancing Cell Culture Understanding in the Development of Biopharmaceuticals by Integrated First-principle Modelling and Machine-learning

Edoardo Tamiazzo, Gianmarco Barberi, Paloma Diaz-Fernandez, Gary Finka, Pierantonio Facco3091



Towards Cognitive Engineering-driven Knowledge Graphs for Chemical Processes: Serialization of Abstraction Decomposition Hierarchy Using Ontocape

Nazanin Hamedi, Anselm Klose, Leon Urbas3097



Surrogate-based Optimization of the Opex of a Modular Plant for Biogas Conversion to Methanol Using the Mads Algorithm

Luis Felipe Sanchez Martinez, Andrea Galeazzi, Flavio Manenti3103



Toward Autocorrection of Chemical Process Flowsheets Using Large Language Models

Lukas Schulze Balhorn, Marc Caballero, Artur M. Schweidtmann3109



Transfer Learning of Hydroprocessing Model from Fossil Feedstocks to Waste Plastic Pyrolysis Oil

Warumporn Pejpichestakul, Per Julian Becker, Benoit Celse3115



Data-driven Forecasting for Anomaly Detection in a Compressor Unit

Aycan Sapmaz, Asli Yasmal, Gizem Kusoglu Kaya, Yasin Utar, Baris Akg�n3121



Policy Explanation of Reinforcement Learning Agent in Chemical Process Safety

Kinga Szatmari, Sandor Nemeth, Alex Kummer3127



Machine Learning Based Modeling and Optimization of an Industrial Thermal Cracking Furnace

Melike Duvanoglu, Gizem Kusoglu Kaya, Onur Savran, Erdal Aydin3133



Completing Partial Reaction Equations with Rule and Language Model-based Methods

Matthijs Van Wijngaarden, Gabriel Vogel, Jana Marie Weber3139



Lstm-based Soft Sensor for the Prediction of Microalgae Growth

Tehreem Syed, Shyam Kalliadan, Jonathan M�dler, Kris Laukens, Luc Roef, Leon Urbas3145



Adaptive Data-driven Modelling and Forecasting of Effluent Treatment Plants

Rihab Abdul Razak, Arvind Ravi, Resmi Suresh, Koen De Leeuw, Jose M. Gonzalez3151



A Comparative Study of Data-driven Offline Reinforcement Learning for Fed-batch Process Control

Omid Sobhani, Furkan Elmaz, Michiel Robeyn, Johan Van Den Hauwe, Shahab Pormoradi Gerdposhteh, Benedict Carius, Kevin Mets, Siegfried Mercelis3157



Supporting Carbon Capture, Utilization, and Storage Supply Chains (ccus) with Blockchain Technology: a Sustainable Solution for Climate Change Mitigation

Manar Y. Oqbi, Dhabia M. Al-Mohannadi3163



Hydrothermal Liquefaction Data for Use in Machine Learning Models

Geert Haarlemmer, Lucie Matricon, Anne Roubaud3169



Application of a Predictive Maintenance Strategy Based on Machine Learning in a Used Oil Refinery

Francesco Negri, Andrea Galeazzi, Francesco Gallo, Flavio Manenti3175



A Novel Hybrid Framework Integrating Artificial Intelligence and Mathematical Programming Approaches for Chemical Batch Scheduling

Dan Li, Taicheng Zheng, Jie Li3181



Benders Decomposition to Integrate Milp and Discrete-event Simulation for Flowshop Scheduling

Roderich Wallrath, Edwin Zondervan, Meik Franke3187



High-dimensional Derivative-free Optimization via Trust Region Surrogates in Linear Subspaces

Damien Van De Berg, Nilay Shah, Antonio Del Rio Chanona3193



Sequential Design of Experiments for Parameter Estimation with Markov Chain Monte Carlo

Xinyu Cao, Xi Chen, Lorenz T. Biegler3199



From Legacy Systems to Data Pipelines Modernization in Fermentation Process

Ana�lle Dessaigne, Amelie Briane, Fayza Daboussi, Julien Cescut, David Camilo Corrales3205



A Convexification-based Outer-approximation Method for Convex and Nonconvex MINLP

Zedong Peng, Kaiyu Cao, Kevin C. Furman, Can Li, Ignacio E. Grossmann, David E. Bernal Neira3211



Hybrid Symbolic-numeric Computation Based on Resultant Theory for Process Simulation

Shuhui Zhang, Fei Zhao, Xi Chen3217



Scenario Reduction Methods for Risk-averse Demand Response Scheduling under Price Uncertainty

Sonja H. M. Germscheid, Alexander Mitsos, Manuel Dahmen3223



Hybrid Optimization Strategy Applied to an Industrial Natural Gas Processing Plant

Roymel R. Carpio, Carlos R. Paiva, Thamires A.L. Guedes, Bruno V. Pinho, Tayn� E. G. Souza, Let�cia C. Santos, Leonardo D. Ribeiro, Argimiro R. Secchi3229



Multi-parametric Programming for Design Space Identification

Simon Walsh, Steven Sachio, Cleo Kontoravdi, Diogo Narciso, Maria M. Papathanasiou3235



Unveil the Subconscious Optimum: Near-pareto-optimal Design Alternatives for Industrial Energy System Transformation

Hendrik Schricker, Conrad Luka, Christiane Reinert, D�rthe Franzisca Hagedorn, Niklas Von Der Assen3241



A Cell Expansion Framework for Property-based Automatic Compartmentalization of Computational Fluid Dynamics (cfd) Models

Lide Gonzalez-Sala, Gorka Sanchez Larraona, Paloma Grau, Borja Hernandez3247



Application of Co-simulation Techniques in Process Systems Engineering and Algorithmic Challenges

Alexander Zinser, Martin Arnold3253



Multi-perspective Process Safety Analysis for Process Utility Systems Under Industry 4.0

Qijia Peng, Brent Young3259



Decomposition Methods Applied to the Design of Large-scale CO2 Supply Chains

Jose A. Alvarez-Menchero, Ruben Ruiz-Femenia, Raquel Salcedo-Diaz, Jos� A. Caballero3265



Enhancing Chemical Process Simulation Through a Gpu-optimized Framework: Implementation and Validation of Equation-oriented Methods Using Cuda

Shaoyi Yang, Xufei Tian, Shifeng Qu, Zhaoyang Duan, Minglei Yang, Feng Qian, Wenli Du3271



A Hybrid Evolutionary Algorithm for Multi-energy System Planning Under Uncertainty

Hagen Seele, Florian Seibel, D�rthe Franzisca Hagedorn, Christiane Reinert, Niklas Von Der Assen3277



Cost Optimal Desalinated Water Production

Shashank Prabhakar, Santanu Bandyopadhyay3283



Development of a Computational Tool for the Solution of Optimal Control Problems with Metaheuristic Techniques

Eduardo Herrera-Alvarez, Oscar Daniel Lara-Monta�o, Mayra Margarita May-Vazquez, Fernando Israel G�mez-Castro, Claudia Guti�rrez-Antonio, Manuel Toledano-Ayala3289



Progressive Hedging for Optimization of Tree Ensembles as Objective Functions

Bashar L. Ammari, Sergio Bugosen, Jean-Paul Watson, Emma S. Johnson, Carl D. Laird3295



An Improved Oracle Adaption for Bilevel Programs

Daniel Jungen, Alexander Mitsos3301



Modeling and Economic Optimization of an Industrial Site for Natural Gas Processing: an MINLP Approach

Tayn� E. G. Souza, Argimiro R. Secchi, Let�cia C. Santos3307



Solving Inverse Optimization Problems via Bayesian Optimization

Yen-An Lu, Vikram Kumar, Wei-Shou Hu, Joel Paulson, Qi Zhang3313



Learning Reduced-order Models for Dynamic CO2 Methanation Using Operator Inference

Luisa Peterson, Pawan Goyal, Ion Victor Gosea, Jens Bremer, Peter Benner, Kai Sundmacher3319



Discontinuous Galerkin Spectral Element Method for Continuous Chromatography: Application to the Lumped Rate Model Without Pores

Jesper Frandsen, Jan Michael Breuer, Eric Von Lieres, Johannes Schm�lder, Jakob K. Huusom, Krist V. Gernaey, Jens Abildskov3325



A Multi-agent System for Hybrid Optimization

Eric S. Fraga, Veerawat Udomvorakulchai, Lazaros G. Papageorgiou3331



Graphical Deterministic Equivalent Algorithm for Robust Process Optimization

Albertus Fuad, Edwin Zondervan, Meik Franke3337



Portfolio-based Strategy for Bayesian Optimization for Autonomous Selection of Multiple Acquisition Functions and Hyperparameters

Runzhe Liang, Haoyang Hu, Zhihong Yuan3343



Evaluation Method for Power-to-liquids Concepts for E-kerosene Production

Fredrik Nyholm, Henrik Saxen3349



Tsec: an Efficient Transition State Search Tool Driven by Machine Learning Potential

Kun Tang, Lei Zhang, Qingwei Meng, Jian Du, Qilei Liu3355



Supply Chain Optimization for Biopropane Production in Brazil

Larissa Thais Bruschi, Luiz Alexandre Kulay, Mois�s Teles Dos Santos3361



Coupling Rule-based Reasoning, Exergy Analysis and Pinch Analysis to Optimize and Improve the Energy Efficiency of Processes

Noha-Lys Senoussaoui, Rapha�le Th�ry H�treux, Gilles Hetreux3367



Scalable Modeling of Infinite-dimensional Nonlinear Programs with Infiniteexamodels.jl

Joshua Pulsipher, Sungho Shin3373



Bayesian Optimization Priors for Efficient Variational Quantum Algorithms

Farshud Sorourifar, Diana Chamaki, Norm M. Tubman, Joel Paulson, David E. Bernal Neira3379



Numerical Simulation and Experimental Validation of a Wind Turbine Using Generative Design

Martin Grardel, Cabrel Kengne Tokam, Maxime Denis, Olivier Bain, Arnaud Dujany3385



Development of an Energy Mix Evaluation Method of an Infrastructure Based on a Multi-layered Territorial Approach.

Julien Jean Victor, Chlo� Labauge, Philippe Trubert, Augustin Mpanda, Laurent Fontanelli, Sebastien Potel, Arnaud Dujany3391



Data-driven Robust Hydrogen Infrastructure Planning Under Demand Uncertainty Using a Hierarchical-based Decomposition Method

Xu Zhou, Margarita E. Efthymiadou, Lazaros G. Papageorgiou, Vassilis M. Charitopoulos3397



Case Study on Quality Assurance of Third-party Models for Co-simulation Using Fmi

Isabell Viedt, Rene Lorenz, Leon Urbas3403



Fast Algorithm for the Continuous Solution of the Population Balance Equation

Menwer Attarakih, Mark W. Hlawitschka, Hans-J�rg Bart3409



A Logic-based Implementation of the Lp/nlp Branch and Bound Algorithm

Ruben Ruiz-Femenia, Juan Javaloyes-Ant�n, Jos� A. Caballero3415



Fastman-jmp: All-in-one Tool for Data Mining and Model Building

Kyle Territo, Jose Romagnoli3421



A Fuzzy Interval Type 2 Logic Approach with Bow-tie Technique and Sensitivity Analysis

Vitor A. O. Silva, Raphael A. Santana, Raphael I. Tsukada, Savio S.V. Vianna, Flavio Vasconcelos da Silva3427



Disjunctive Programming Meets Qubo

Pedro Maciel Xavier, Pedro Ripper, Joshua Pulsipher, Joaquim Dias Garcia, Nelson Maculan, David E. Bernal Neira3433



Adopting Circular Economy Principals for Sustainable Manufacturing

Konstantina Stylianopoulou, Emilia Kondili, Christiana Papapostolou, John K. Kaldellis3439



Decarbonization Strategies by Industrial Ecology

Marianne Boix, Henri De la Vaissi�re De Verduzan, St�phane N�gny3445



Comparison of Domino Effect Analysis Tools Using Graph Theory

Niki Moradmand-Nia, Nelly Olivier-Maget, Franck Prats3451



Coping with Sustainability, Circularity and Complexity in Optimizing Industrial Symbiosis Networks Among Distributed Chemical Processes

Th�r�se Lee Chan, David A. Janes, Kyle Joshua3457



Prototyping Cloud Application for Regional Green Transformation Supported by Prospective Life Cycle Assessment

Yuichiro Kanematsu, Shoma Fujii, Yuko Oshita, Satoshi Ohara, Atsushi Komori, Daisuke Shimotoku, Katsura Iizuka, Junya Kawase, Hiroki Kobayashi, Yasunori Kikuchi3463



On Numerical Stability of Relaxations of Generalized Disjunctive Programs

Milos Bogataj, Zdravko Kravanja3469



Biological Analogues in Advanced Water Treatment with Application in 3D Printed Graphene Oxide and Metal-halide Bixoyclz/agcl Composite Heterogeneous Photocatalysis

Evans M.N. Chirwa, Shepherd M. Tichapondwa, Fisseha A. Bezza, Emmanuel O. Ichipi, Rachel Mugumo, Osemeikhian Ogbeifun, Dorcas O. Adenuga, Zakhele A. Khumalo, Emomotimi E. Bamuza-Pemu3475



Design Optimal Experiments for Parameter Identification of a Dynamic Model with Perturbed Inputs

Ran Wang, Antonios Armaou, Robert Rioux3481



Priority Planning for Methane Emissions Abatement via Marginal Abatement Cost Curves (mac) and Shapley-shubik Power Index

Adeline Shu Ting Tan, Jaya Prasanth Rajakal, Mohammad Lameh, Dhabia M. Al-Mohannadi, Bing Shen How, Viknesh Andiappan3487



Fermentai: Large Language Models in Chemical Engineering Education for Learning Fermentation Processes

Fiammetta Caccavale, Carina L. Gargalo, Krist V. Gernaey, Ulrich Kr�hne3493



Interactive Coding Templates for Courses and Undergraduate Research Using Matlab Live Scripts

Ashlee N. Ford Versypt, Carley V. Cook, Austin N. Johns3499



Teaching Process Design Quo Vadis?

Daniel R. Lewin, Thomas A. Adams II, Dominik Bongartz, Gr�goire L�onard, Seyed Soheil Mansouri, Fernando G. Martins, Iqbal M. Mujtaba, Edwin Zondervan3505



Serious Games for Active Learning in Optimization of Chemical Processes

Ismael Diaz, Emilio J. Gonzalez, Maria Gonzalez-Miquel, Manuel Rodriguez3511



Simulated-experimental Cross Validation of Multistage Batch Distillation for Water/propylene Glycol Separation as Educational Exercise

Giulia Tonsi, Elisa Zanella, Arian Grainca, Andrea Bonetti, Pietro Cassinerio, Carlo Pirola3517



An Open-source Software for Low-code Implementation of Fuzzy Logic for Process Engineering

Raphael A. Santana, Vitor A. O. Silva, Tiago F. Souza, Vitor M. V. Cruz, Ana M.F. Fileti, Flavio Vasconcelos da Silva3523



Merging Digitalization Tools for Training the New Generation of Bio-chemical Engineers: Challenges and Perspectives

Oscar Andres Prado-Rubio, Jakob K. Huusom3529



Virtual Reality and Digital Twins for Enhanced Learning in Chemical Engineering

Andrea Galeazzi, Paolo Marenghi, Lamberto Du�, Maurizio Galardo, Renato Rota, Susanna Sancassani, Flavio Manenti3535

Authors

Flavio Manenti Dipartimento di Chimica, Materiali e Ingegneria Chimica, Politecnico di Milano, Milano, Italy. Flavio Manenti (Dipartimento di Chimica, Materiali e Ingegneria Chimica, Politecnico di Milano) is experienced in chemical process simulations for design and operational purposes. He developed AG2ST technology for thermal conversion of CO2 and codeveloped BzzMath library. He is the author of peer-reviewed papers and books on the topic and is the President of the Computer Aided Process Engineering (CAPE) Working Party at the European Federation of Chemical Engineering. G.V. Rex Reklaitis Forney Hall of Chemical Engineering, Purdue University, West Lafayette, IN, USA.