A Review on Diverse Neurological Disorders. Pathophysiology, Molecular Mechanisms, and Therapeutics

Table of Contents

1. Epidemiology and risk factors of mental disorders
2. Bacterial meningitis and neurological disorder
3. An overview on Helminthic brain infections in humans
4. Helminthic infections of the central nervous system
5. Pathogenesis and overview of central nervous system tuberculosis
6. Tuberculosis of central nervous system
7. An overview on tetanus, diphtheria, and diverse bacterial infections of the CNS
8. Tetanus, diphtheria and other bacterial infections of central nervous system
9. Pathogenesis and treatment of syphilis
10. Fungal infection of central nervous system
11. An overview on the fungal infections of the nervous system
12. Acute viral encephalitis, meningitis, and cerebral malaria
13. Neurological complications of COVID-19 infections
14. Genetic addiction risk analysis for “Preaddiction Severity Index” (PAI): A neurobiological behavioral octupus
15. Addressing the role of endocannabinoid system in rabies infection and its potential for modulation
16. Pathogenesis and Treatment of Rabies
17. An overview of pathophysiology and therapeutic approaches of Alzheimer’s disease and Parkinson’s disease
18. Ataxia and motor neuron diseases
19. Multiple system atrophy
20. Progressive supranuclear palsy
21. Epilepsy and Neurodegeneration
22. HIV/AIDS Neurological Disorders
23. Neurodegeneration and Motor Deficits
24. Neurodegeneration in autoimmune central nervous system infection
25. Inflammation and neurodegeneration in multiple sclerosis
26. Autophagy and mitophagy in amyotrophic lateral sclerosis
27. Excitation-inhibition balance in diseases of the brain: Role of NMDA and GABA receptors
28. Nutraceuticals for the prevention of stroke and cerebrovascular injury: An overview
29. HIV infection, type 1 interferons, and immune competence: Correlating brain immunity to neurodegeneration
30. Neuroinflammation: Role of adhesion molecules and signaling networks in neurovascular systems
31. Influence of Axonal Pathology in Traumatic Brain Injury
32. Axonal Pathology in Traumatic Brain Injury: An Overview
33. Ocular neurodegenerative disorders
34. Stress-associated neurodegenerative disorders: A mechanistic exploration
35. Diverse stress and neurodegeneration: An overview
36. Neurodegenerative diseases and circadian rhythm dysfunction: A bidirectional nexus
37. Advancing age, nutraceuticals, and neuroprotection
38. Novel treatments for neurodegenerative disorders predominantly presenting in children and young adults
39. CNS drugs: Classification, characterization, and binding properties towards biomacromolecules
40. The role of gut microbiome in insomnia
41. Novel therapeutics for diverse neurological disorders
42. Elucidating the potential of natural bioactive compounds in neuroprotection
43. Vitamins, micronutrients, antioxidants, and nutraceuticals in neuroprotection: An overview
44. Olive oil and mediterranean diet: The importance of olive oil constituents, and mainly of its polyphenols, in human health The redox system Xenohormesis hypothesis
45. Probiotics protect against progressive deterioration of motor functions and Parkinson’s disease
46. Neuroprotective abilities of vitamins, micronutrients, antioxidants, and nutraceuticals
47. Nutraceuticals and Natural Products in the treatment of neurological disorders
48. Unprecedented prospects as forthcoming drug targets: New boulevard in the cure and treatment of neurodegenerative disorders
49. The Threats and Therapeutics of Neurodegenerative Disorders: A Commentary

Authors

Rameshwar Nath Chaurasia Department of Neurology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India. Rameshwar Nath Chaurasia MBBS, MD, DM, MAMS received his D.M. in Neurology in 2009 from King George Medical University, Lucknow, India. He did his MBBS and M.D.(Medicine) from Institute of Medical Sciences, Banaras Hindu University, Varanasi, India. At present he is Professor & Head in the Department of Neurology, Institute of Medical Sciences, Banaras Hindu University, Varanasi. He served in the University at various administrative posts like Student Advisor, Anti Ragging Committee of University team, Deputy Chief Proctor etc.,He also served as founder Nodal officer of Ayushman Bharat Yojana (Biggest Health Scheme Yojana in World) in Sir Sundar Lal Hospital, I.M.S. BHU. He is Executive Council Member of AIIMS, Gorakhpur, Uttar Pradesh, India.

Dr. Chaurasia received various awards/prizes from different Scientific/Non-scientific organizations and Societies for creating awareness about various neurological diseases in societies. His passion is to serve the needy people of India living in remote areas of different states of India by arranging health camps with the help of National Medicos Organization and Sewa Bharati of India. He also got teacher awards on teacher's day from Governor and Chief Minister of Uttar Pradesh, India in 2017 and 2021 respectively. Dr R N Chaurasia has contributed >90 research papers in various peer reviewed national and international journals. He also contributed >10 book chapters in various books. He is reviewer of many national and international peer reviewed journals (>6). His main area of research is in the field of stroke, Epilepsy, cognitive science and CNS infections. He is member of various academic bodies in the field of neurosciences like Indian Academy of Neurology, Neurological Society of India, International Parkinson and Movement Disorder Society & American Academy of Neurology etc. Sunny Ohia Professor, College of Pharmacy and Health Sciences, Texas Southern University, Houston, TX, USA. Sunny Ohia, Ph.D., FARVO, FAS is a Professor of Pharmacology in the College of Pharmacy and Health Sciences at Texas Southern University. Dr. Ohia has over 28 years of experience in higher education having served as a member of faculty in five universities in Canada and the United States (U.S.). He holds other academic appointments as adjunct professor of ophthalmology and visual sciences at the University of Nebraska Medical Center, Omaha and as an adjunct professor of integrative biology and pharmacology at the University of Texas Health Sciences Center in Houston. Dr. Ohia is a Fellow of the Nigerian Academy of Science and a Fellow of the Association for Research in Vision and Ophthalmology. He is the author of more than 250 original papers, book chapters, books, and abstracts and, holds three U.S. and five international Patents for his scientific work. Dr. Ohia received his Ph.D. in pharmacology from the University of Glasgow, in Scotland, United Kingdom. Dr. Ohia completed postdoctoral research training fellowships in neuroscience and in ophthalmology/visual sciences at Memorial University of Newfoundland, Canada and the University of Louisville, School of Medicine, KY, respectively. Debasis Bagchi Professor, Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, USA; Chief Scientific Officer, Cepham Research Center, Piscataway, New Jersey; Adjunct Faculty, Texas Southern University, Houston, Texas, USA. Debasis Bagchi, PhD, MACN, CNS, MAIChE, received his Ph.D. in Medicinal Chemistry in 1982. He is a Professor in the Department of Pharmacological and Pharmaceutical Sciences at the University of Houston College of Pharmacy, Houston, TX, and Chief Scientific Officer at Cepham Research Center, Piscataway, NJ, Adjunct Faculty in Texas Southern University, Houston, TX. He served as the Senior Vice President of Research & Development of InterHealth Nutraceuticals Inc, Benicia, CA, from 1998 until Feb 2011, and then as Director of Innovation and Clinical Affairs, of Iovate Health Sciences, Oakville, ON, until June 2013. Dr. Bagchi received the Master of American College of Nutrition Award in October 2010. He is the Past Chairman of International Society of Nutraceuticals and Functional Foods (ISNFF), Past President of American College of Nutrition, Clearwater, FL, and Past Chair of the Nutraceuticals and Functional Foods Division of Institute of Food Technologists (IFT), Chicago, IL. He is serving as a Distinguished Advisor on the Japanese Institute for Health Food Standards (JIHFS), Tokyo, Japan. Dr. Bagchi is a Member of the Study Section and Peer Review Committee of the National Institutes of Health (NIH), Bethesda, MD. He has published 321 papers in peer reviewed journals, 30 books, and 18 patents. Dr. Bagchi is also a Member of the Society of Toxicology, Member of the New York Academy of Sciences, Fellow of the Nutrition Research Academy, and Member of the TCE stakeholder Committee of the Wright Patterson Air Force Base, OH. He is also Associate Editor for the Journal of Functional Foods, Journal of the American College of Nutrition, and the Archives of Medical and Biomedical Research, and is also serving as Editorial Board Member of numerous peer reviewed journals, including Antioxidants & Redox Signaling, Cancer Letters, Toxicology Mechanisms and Methods, and The Original Internist, among others.