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Biological Insights of Multi-Omics Technologies in Human Diseases

  • Book

  • May 2024
  • Elsevier Science and Technology
  • ID: 5917548

Biological Insights of Multi-Omics Technologies in Human Diseases provides detailed information about the basics of multi-omic technologies, including ethics, historical perspective, science, drug discovery, and development and metabolism. With a strong focus on the practical application of omics approaches in cancer, cardiovascular, neurology, respiratory, viral, gastroenterology, autoimmune diseases, PCOS and tuberculosis, this book also includes special topics related to COVID-19 and Machine learning approaches. In 13 chapters, this book provides comprehensive coverage of the challenges and opportunities facing the therapeutic implications of multi-omics from academic, regulatory, pharmaceutical, socio-ethical, and economic perspectives. The chapters are designed in a well-defined chronology such that readers will intuitively understand the central idea. This book is an ideal resource for health professionals, scientists and researchers, nutritionists, health practitioners, students, and all those who wish to broaden their knowledge in the allied field.

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Table of Contents

1. Multiomics approaches in human diseases 2. Crosstalk of multiomics approaches with medicinal plants of therapeutic importance 3. Multiomics approaches in Cancer 4. Multiomics in Cardiovascular diseases (CVD) 5. Multiomics for understanding Neurodegenerative disorders 6. Multiomics in Gastrointestinal disorders 7. Multiomics in Human viral infections 8. Multiomics in autoimmune diseases 9. Multiomics in respiratory disorders 10. Multiomics in Polycystic Ovarian Syndrome (PCOS) 11. Multi-Omics Technologies Applied to Tuberculosis Drug Discovery 12. Multiomics in COVID-19 13. Machine learning approaches for multi-omics data analysissignaling dysregulation, potential proteomic techniques, therapeutic strategies, and future perspectives. 14. Organ on a chip 15. Biomarkers of Respiratory Diseases

Authors

Aarif Ali Department of Clinical Biochemistry, School of Biological Sciences, University of Kashmir, India. Aarif Ali (Ph.D.) has recently completed Doctor of Philosophy in Clinical Biochemistry at University of Kashmir and has collaboratively worked and published research papers in different reputed National as well as International journals. He has obtained his BSc from SP College affiliated with University of Kashmir, MSc from University of Kashmir (J&K, India) respectively. Dr. Ali is reviewer of several journals like Plant Cell Biotechnology and Molecular Biology (PCBMB), Current Journal of Applied Science and Technology and Asian Journal of Advances in Medical Science. Muneeb U Rehman College of Pharmacy, King Saud University, Riyadh, Saudi Arabia. Muneeb U Rehman (Ph.D.) is a Faculty member at College of Pharmacy, King Saud University, Riyadh, Saudi Arabia. He holds a doctorate in Toxicology (specialization in cancer biology and natural product research) from Jamia Hamdard, New Delhi, India. Dr. Rehman has more than 10 years of research and teaching experience in the field of toxicology, cancer biology, natural product pharmacology and pharmacogenomics. He is the recipient of several national and international fellowships and awards. He has published more than 100 research papers in peer-reviewed, international journals, and has 5 edited books and 30 book chapters. Dr. Rehman is on the editorial boards and is a reviewer of several high-impact, international scientific journals. He is also a life member of various international societies and organizations. Currently, Dr. Rehman is engaged in studying the molecular mechanisms of cancer prevention by natural products and the role of pharmacogenomics and toxicogenomics in evaluating the effectiveness and safety of drugs. Sheikh Bilal Ahmad Division of Veterinary Biochemistry, Faculty of Veterinary Sciences, SKUAST-K, Shuhama, Alustang, Srinagar, India.

Dr. Sheikh Bilal Ahmad is a Senior faculty member at the Division of Veterinary Biochemistry, Faculty of Veterinary Sciences, SKUAST-K, Shuhama, Alustang, Srinagar, India. Dr. Sheikh Bilal Ahmad holds Doctorate in Biochemistry from Department of Biochemistry and Bioprocess Technology, Sam Higginbottom Institute of Agriculture, Technology and Sciences Allahabad, India. Dr. Sheikh Bilal Ahmad has more than twenty years of research and teaching experience in veterinary biochemistry, cancer biology, molecular biology and genetics. He has published more than 100 research papers in peer-reviewed, international journals, and has more than 30 book chapters. Dr. Sheikh Bilal Ahmad serves as an editorial board member and reviewer of several high-impact, international scientific journals.

Azher Arafah Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia. Azher Arafah works in the Department of Clinical Pharmacy, College of Pharmacy at King Saud University in Riyadh, Saudi Arabia.