Chemotherapy-Induced Nausea and Vomiting (CINV) Market Report 2025

This report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market’s historic and forecast market growth by geography.

The chemotherapy-induced nausea and vomiting (CINV) market size has grown strongly in recent years. It will grow from $2.92 billion in 2024 to $3.15 billion in 2025 at a compound annual growth rate (CAGR) of 7.9%. The growth in the historic period can be attributed to growth in chemotherapy use, improved antiemetic agents, clinical guidelines, patient advocacy.

The chemotherapy-induced nausea and vomiting (CINV) market size is expected to see strong growth in the next few years. It will grow to $4.2 billion in 2029 at a compound annual growth rate (CAGR) of 7.5%. The growth in the forecast period can be attributed to personalized medicine, advances in antiemetic agents, telehealth and remote monitoring, health equity initiatives. Major trends in the forecast period include combination antiemetic therapies, supportive care services, digital health tools, survivorship care.

The increasing incidence of cancer is set to drive the expansion of the chemotherapy-induced nausea and vomiting (CINV) market in the foreseeable future. The proliferation of cancer occurs when certain cells in the body undergo uncontrolled growth and spread to other parts of the body. With cancer cases on the rise, there is a growing impetus to develop more effective and targeted antiemetic treatments to alleviate CINV, a distressing side effect of chemotherapy. This heightened focus on managing CINV has led to advancements in understanding its underlying mechanisms and the creation of innovative therapies. For example, as of January 2023, the American Cancer Society (ACS) anticipates around 1.9 million new cancer cases (approximately 5,370 cases per day) and 609,820 cancer-related deaths (about 1,670 deaths per day) in the United States for 2023. Consequently, the increasing prevalence of cancer will be a driving force behind the chemotherapy-induced nausea and vomiting (CINV) market.

The growth of the chemotherapy-induced nausea and vomiting (CINV) market is expected to be driven by the increasing favorable regulatory initiatives. Regulatory initiatives are actions undertaken by regulatory bodies to develop, enforce, or implement regulations. These initiatives are aimed at enhancing the prevention and management of chemotherapy-induced nausea and vomiting (CINV) by establishing guidelines and policies. For example, in October 2024, the U.S. Food and Drug Administration (FDA), a federal agency focused on public health protection, reported that in 2023, its Center for Drug Evaluation and Research (CDER) approved 55 new drugs specifically for chemotherapy-induced nausea and vomiting (CINV). As a result, the growing favorable regulatory initiatives are propelling the growth of the CINV market.

Major companies in the chemotherapy-induced nausea and vomiting (CINV) market are focusing on new product innovations, such as fixed intravenous antiemetics, to gain a competitive edge. A fixed intravenous antiemetic refers to a predetermined dose of medication delivered via IV to prevent or treat nausea and vomiting, commonly used in chemotherapy or post-surgery contexts. For example, in January 2023, Glenmark Pharmaceuticals Limited, an India-based pharmaceutical manufacturer, launched AKYNZEO I.V. in India, the first fixed intravenous antiemetic combination designed to prevent chemotherapy-induced nausea and vomiting (CINV). This product combines netupitant and palonosetron, addressing both acute and delayed phases of nausea and vomiting. It offers single-dose convenience, higher complete response rates, and improved quality of life for cancer patients. Clinical studies indicate it is especially effective for patients undergoing highly emetogenic chemotherapy.

In January 2022, Cumberland Pharmaceuticals Inc., a U.S.-based specialty pharmaceutical firm, acquired SANCUSO (granisetron transdermal patch) from Kyowa Kirin Inc. for $13.5 million. This acquisition granted Cumberland full control over the U.S. rights to SANCUSO, a chemotherapy-induced nausea and vomiting (CINV) drug. This included responsibility for marketing, promotion, distribution, manufacturing, and medical support operations related to the product. Kyowa Kirin Inc. is a U.S.-based subsidiary of Kyowa Kirin Co. Ltd. in Japan, a specialty pharmaceutical company that specializes in developing innovative medicines used for preventing CINV.

Major companies operating in the chemotherapy-induced nausea and vomiting (cinv) market are Pfizer Inc., Roche Holding AG, Merck & Co. Inc., AbbVie Inc., Novartis AG, AstraZeneca PLC, GlaxoSmithKline PLC, Baxter International Inc., Teva Pharmaceuticals Industries Ltd., Bausch Health Companies Inc., Eisai Co. Ltd., Jazz Pharmaceuticals PLC, Ono Pharmaceutical Co. Ltd., Dr. Reddy’s Laboratories Ltd., Kyowa Kirin Inc., Amneal Pharmaceuticals Inc., Mundipharma International Limited, Insys Therapeutics Inc., Lupin Limited, Helsinn Holding S.A., Heron Therapeutics Inc., Camurus AB, Cadila Pharmaceuticals Limited, Acacia Pharma Ltd., Soligenix Inc.

North America was the largest region in the chemotherapy-induced nausea and vomiting (CINV) market in 2024. The regions covered in chemotherapy-induced nausea and vomiting (CINV) report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa. The countries covered in the chemotherapy-induced nausea and vomiting (CINV) market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

The chemotherapy-induced nausea and vomiting (CINV) market consists of revenues earned by entities by providing services such as pharmacologic therapy and nonpharmacologic therapy. The market value includes the value of related goods sold by the service provider or included within the service offering. The chemotherapy-induced nausea and vomiting (CINV) market also includes the sales of such as olanzapine, dexamethasone, cannabinoids, metoclopramide, promethazine and prochlorperazine. Values in this market are ‘factory gate’ values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

Chemotherapy-induced nausea and vomiting (CINV) is a condition characterized by the sensation of nausea and vomiting, often arising as a side effect of chemotherapy treatment. This common side effect can significantly impact the quality of life and treatment outcomes for many cancer patients. Fortunately, CINV can be effectively managed and treated through medications and lifestyle adjustments.

CINV presents in various forms, including injectables, oral medications, and transdermal patches. Injectables are chemical substances administered via injection to produce various therapeutic effects. Medications used for CINV management belong to different drug classes, such as 5-HT3 receptor antagonists, neurokinin-1 receptor antagonists, corticosteroids, cannabinoids, and others. The risk of developing CINV varies, with emetogenic risks categorized into highly emetogenic chemotherapy (HEC), moderately emetogenic chemotherapy (MEC), and low emetogenic chemotherapy (LEC). These treatments and medications are distributed through multiple channels, including CINV hospitals, cancer research institutes, retail pharmacies, online pharmacies, and drug stores. They find application in various medical fields such as gynecology, urology, gastrointestinal surgery, and others.

The chemotherapy-induced nausea and vomiting (CINV) market research report is one of a series of new reports that provides chemotherapy-induced nausea and vomiting (CINV) market statistics, including chemotherapy-induced nausea and vomiting (CINV) industry global market size, regional shares, competitors with a chemotherapy-induced nausea and vomiting (CINV) market share, detailed chemotherapy-induced nausea and vomiting (CINV) market segments, market trends and opportunities and any further data you may need to thrive in the chemotherapy-induced nausea and vomiting (CINV) industry. This chemotherapy-induced nausea and vomiting (CINV) market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

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