Chromatography Columns Market Report 2026

The chromatography columns market size has grown strongly in recent years. It will grow from $8.98 billion in 2025 to $9.78 billion in 2026 at a compound annual growth rate (CAGR) of 8.9%. The growth in the historic period can be attributed to expansion of pharmaceutical and biotechnology research, growth in protein purification applications, increasing adoption of chromatography in food testing, availability of standardized columns, rising academic research activities.

The chromatography columns market size is expected to see rapid growth in the next few years. It will grow to $14.41 billion in 2030 at a compound annual growth rate (CAGR) of 10.2%. The growth in the forecast period can be attributed to increasing biopharmaceutical production, rising demand for personalized medicine, expansion of advanced analytical techniques, growing focus on sustainable separation processes, increasing automation in laboratory workflows. Major trends in the forecast period include increasing adoption of prepacked chromatography columns, rising demand for high-purity separation solutions, growing use in biopharmaceutical manufacturing, expansion of automated chromatography systems, enhanced focus on process efficiency.

The increasing demand for biopharmaceutical products is expected to propel the growth of the chromatography columns market going forward. Biopharmaceutical products are medicinal substances derived from biological sources such as humans, animals, or microorganisms, consisting of sugars, proteins, nucleic acids, living cells, or tissues. They are produced through extraction or partial synthesis using these biological materials. Chromatography columns play a vital role in separating and purifying molecules, ensuring that biopharmaceutical products are pure and free from contaminants. For instance, in January 2023, according to Cardinal Health Inc., a US-based healthcare company, the number of FDA-approved biosimilars in the US increased from 33 in January 2022, with 21 available on the market, to 40 in 2023, with 25 commercially available. Therefore, the rising demand for biopharmaceutical products is driving the growth of the chromatography columns market.

Major companies operating in the chromatography columns market are developing innovative products such as size exclusion chromatography (SEC) columns to offer reliable solutions to customers. SEC columns separate molecules based on size using porous particles packed within the column; molecules are separated depending on their ability to enter and elute from these pores. For example, in August 2023, Waters Corporation, a US-based manufacturer of analytical laboratory instruments, introduced the Waters XBridge Premier GTx BEH SEC columns. This new range of SEC columns is designed to enhance analytical processes and reduce costs associated with gene therapies, particularly those involving adeno-associated viral (AAV) vectors. When combined with light scattering technologies from Waters’ Wyatt Technology portfolio, these columns provide more detailed data in a single test, improving the development of advanced gene delivery methods.

In January 2023, Astrea Bioseparations, a UK-based biotechnology company, acquired Delta Precision Limited for an undisclosed amount. The acquisition aims to strengthen Astrea’s bioprocessing capabilities by expanding its portfolio of purification solutions for advanced therapeutics. Delta Precision Limited is a UK-based manufacturer of chromatography columns.

Major companies operating in the chromatography columns market are Metrohm AG, Siemens AG, Hitachi Ltd., Thermo Fisher Scientific Inc., Danaher Corporation, Merck KGaA, Corning Incorporated, Tosoh Corporation, Agilent Technologies Inc., Sartorius AG, Shimadzu Corporation, Daicel Corporation, PerkinElmer Inc., Waters Corporation, Bio-Rad Laboratories Inc., Integra LifeSciences Holdings Corporation, Handtmann Group, Hamilton Company, Luminex Corporation, Restek Corporation, Cole-Parmer Instrument Company LLC, Phenomenex Inc., Macherey-Nagel GmbH & Co. KG, Qingdao QShenghan Chemical Co. Ltd, Biotage AB, KNAUER Wissenschaftliche Geräte GmbH, Ace Glass Incorporated, Carl Roth GmbH, Dawn Scientific Inc.

North America was the largest region in the chromatography columns market in 2025. Asia Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the chromatography columns market report are Asia-Pacific, South East Asia, Western Europe, Eastern Europe, North America, South America, Middle East, Africa. The countries covered in the chromatography columns market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Taiwan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

The chromatography column market consists of sales of packed columns and capillary columns. The values in this market are ‘factory gate’ values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

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