Chromatography Columns Market Report 2025

This report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market’s historic and forecast market growth by geography.

The chromatography columns market size has grown strongly in recent years. It will grow from $8.4 billion in 2024 to $9.09 billion in 2025 at a compound annual growth rate (CAGR) of 8.2%. The growth in the historic period can be attributed to growing biopharmaceutical industry, demand for personalized medicine, environmental testing and monitoring, food and beverage quality control.

The chromatography columns market size is expected to see strong growth in the next few years. It will grow to $13.16 billion in 2029 at a compound annual growth rate (CAGR) of 9.7%. The growth in the forecast period can be attributed to increasing focus on environmental sustainability, globalization of pharmaceutical manufacturing, increased focus on monolith columns, adoption of preparative chromatography. Major trends in the forecast period include advancements in column technologies, high-performance liquid chromatography, multi-modal chromatography columns, customized chromatography solutions, collaborations and partnerships.

The trajectory of the chromatography columns market is expected to be fueled by the escalating demand for biopharmaceutical products in the foreseeable future. Biopharmaceuticals, derived from biological sources such as humans, animals, or microorganisms, encompass a spectrum of medicinal substances comprising sugars, proteins, nucleic acids, living cells, or tissues. These substances are either extracted or partially synthesized from biological sources. Chromatography columns play a pivotal role in the separation and purification of diverse molecules, ensuring the eventual biopharmaceutical product attains purity and is devoid of contaminants. EuroDev reported in August 2023 that biopharmaceutical revenues in Germany surged to $1.36 billion (€1.2 billion) in the third quarter of 2022, marking a remarkable 34% increase compared to the corresponding period in 2021. Hence, the burgeoning demand for biopharmaceutical products acts as a primary driver propelling the growth of the chromatography column market.

The upswing in monoclonal antibody (mAb) manufacturing is anticipated to drive the expansion of the chromatography column market. Monoclonal antibodies, engineered in laboratories to imitate the immune system's defense mechanisms against harmful pathogens such as viruses, play a crucial role in chromatography columns. These antibodies offer specificity and selectivity essential for purifying, analyzing, and characterizing biological samples. Notably, data from the National Library of Medicine in May 2023 revealed that a significant number of patients testing positive for SARS-CoV-2 infection in England and Italy received doses of monoclonal antibodies or antivirals for early COVID-19 treatment from December 2021 to October 2022. This surge in monoclonal antibody administration illustrates their increasing significance in combating viral infections. Consequently, the rise in manufacturing monoclonal antibodies contributes significantly to driving the growth of the chromatography column market.

Key industry players within the chromatography column market are actively engaged in the development of innovative products, such as size exclusion chromatography (SEC) columns, to cater to customer demands effectively. SEC columns serve the purpose of separating molecules based on size, utilizing porous particles packed within the column. This technique allows molecules to be separated based on their ability to enter and elute from the pores. For instance, in August 2023, Waters Corporation, a renowned US-based manufacturer of analytical laboratory instruments, introduced the new Waters XBridge Premier GTx BEH SEC columns. This novel range of SEC columns aims to enhance the analytical process and reduce expenses associated with gene treatments, specifically those involving adeno-associated viral (AAV) vectors. Integrating these columns with light scattering technologies from its Wyatt Technology collection enables obtaining more comprehensive data from a single test, thereby improving the production efficiency of these innovative gene delivery methods. This strategic integration of advanced technology signifies a pivotal step towards addressing market challenges and meeting evolving industry demands within the chromatography column sector.

In January 2023, UK-based biotechnology company Astrea Bioseparations acquired Delta Precision Limited for an undisclosed sum. This acquisition is intended to bolster Astrea's bioprocessing capabilities, specifically by expanding its portfolio of purification solutions for advanced therapeutics. Delta Precision Limited, also based in the UK, specializes in manufacturing chromatography columns.

Major companies operating in the chromatography columns market report are Metrohm AG, Siemens AG, Hitachi Ltd., Thermo Fisher Scientific Inc., Danaher Corporation, Merck KGaA, Corning Incorporated, Tosoh Corporation, Agilent Technologies Inc., Sartorius AG, Shimadzu Corporation, Daicel Corporation, PerkinElmer Inc., Quidel Corporation, Waters Corporation, Bio-Rad Laboratories Inc., Integra LifeSciences Holdings Corporation, Handtmann Group, Hamilton Company, Luminex Corporation, Restek Corporation, Cole-Parmer Instrument Company LLC, Phenomenex Inc., Macherey-Nagel GmbH & Co. KG, Qingdao QShenghan Chemical Co. Ltd., Biotage AB, KNAUER Wissenschaftliche Geräte GmbH, Ace Glass Incorporated, Carl Roth GmbH, Dawn Scientific Inc.

North America was the largest region in the chromatography columns market in 2024. Asia Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the chromatography columns market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa. The countries covered in the chromatography columns market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

The chromatography column market consists of sales of packed columns and capillary columns. The values in this market are ‘factory gate’ values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

Chromatography columns are analytical devices crucial for isolating specific chemical compounds from fluid-based mixtures. These instruments play a vital role in compound purification, analysis, and quantification processes across various scientific fields, including chemistry, biology, pharmaceuticals, and environmental science.

The main types of chromatography columns include normal phase chromatography columns, prepacked chromatography columns, and automated chromatography columns. Normal phase chromatography columns utilize a polar stationary phase and a nonpolar mobile phase in liquid chromatography. Chromatography types encompass ion exchange chromatography, affinity chromatography, gas chromatography, gel filtration, and others, with capacities ranging from 1-100 ml to more than 1l. Applications include sample preparation, resin screening, protein purification, anion and cation exchange, desalting, and others, used in nutraceuticals, academics, food and beverages, pharmaceuticals, environmental biotechnology, cosmetics, and more.

The chromatography columns market research report is one of a series of new reports that provides chromatography columns market statistics, including chromatography columns industry global market size, regional shares, competitors with a chromatography columns market share, detailed chromatography columns market segments, market trends and opportunities, and any further data you may need to thrive in the chromatography columns industry. This chromatography columns market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

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